Click here to switch to the map view.

The map label for this gene is selA [H]

Identifier: 108758722

GI number: 108758722

Start: 3890672

End: 3892069

Strand: Direct

Name: selA [H]

Synonym: MXAN_3346

Alternate gene names: 108758722

Gene position: 3890672-3892069 (Clockwise)

Preceding gene: 108759696

Following gene: 108757518

Centisome position: 42.57

GC content: 72.6

Gene sequence:

>1398_bases
ATGGGCGCCCCGTCGAACAGTGGAGACGGTGGGAAGAATGCGCTCTTGCGCGCGCTCCCCTCCGTCGAGCAGCTCCTGCG
GCGCCCGTCGCTGGAACCCCTGTTGAGCGGAGTCCCCAGGGCCCGCGCCGTGGCCGCGCTCCGGCTGGCGGTGGACCGGG
CCCGGGGCCGGTTGGTGGCGTCGGGCGGGCCGGGCTTCGAGGATGCGGACGTCCAGCACGCCCTGGACACGCTGGCCACA
CCGGGGCTGCGGCCCGTGCTCAACGCCACCGGGGTGGTGCTGCACACCAACCTGGGACGCGCACCCCTGGCGGCCTCGGC
CGTGGCGCGCGTGGCGGAGGTGGCTCGGGGGTACTCCAACCTCGAGTACGACCTGGATGAGGGAGAGCGGGGCAGTCGCT
ACGCGCCGTTGGTGGGGCTGCTGCGCTCGCTGACGGGCGCGGAGGACGCGGTCGTCGTCAACAACTGCGCGGGCGCGGTG
CTGCTGGTGCTGGCGGCGTTGGCGTCCGGCCGCGAGTGCGTGGTGTCGCGCGGTGAGCTGGTGGAGATTGGCGGCGGCTT
CCGCGTCCCGGAGGTGATGCGACAGTCGGGCGCGAAGCTGGTGGAGGTGGGCACCACCAACCGGACGCGGCTGTCGGATT
ACTCGGCGGCGCTGGGCCCGGAGTCGGCGCTGCTGGTGAAGGTGCACCGCTCCAACTTCGCGTTGGTGGGCTTCACGGAA
GAGGTGGAGGTCGCGGAGCTCTCGGCGTTGGGCCGCGCGCGCGGCGTGCCGGTGTTCCAGGACCTGGGCGCGGGCGCGCT
GGTGCCGCTGAAGGGCGAGGGCCTGAGCCGGGAGCTCACGGTGGCCCAGGCCGTGGCGGCGGGCGCGGACGTGGTCGCCT
TTTCGGGAGACAAGCTGTTGGGAGGACCCCAGGCGGGAGTCGTGGTGGGCCGGTCTGTGCTGCTGGCACGCATCAAGGCT
CATCCGCTCATGCGGGCCCTGCGGGTGGACAAGCTGACGGTCGCCGCGCTTGAAGCCACCCTGGCGCTGTACCGGGATGG
CCGGGCGGAAGAGGTTCCGGTGCATCGCCTGCTTGCCCAGTCGCCGGAAGACCTGCGCGCCCGAGCGGTACGGCTGCAAG
GCCTGCTGGCGGGGCAGGGTGTGCGTGCGCGGGTGGCCAGCGTGGAGGGGCAGGTGGGTGGGGGTGCCATGCCGCTGGCC
AGGTTGCCGTCCTCCGCGTGCATCCTCACCCTAGGGACGCCGGAAGAATTCCTGGAGCGCCTGCGCGGAGGCATGTCGCC
GGTTATTGGGAGGATCGCGGATGGCGAGGTGCTCCTCGACGTCCGGTGTCTCGAGGAGGAGGAGCTCCAGGCCGTCGCGG
ATGCCGTCGCGGCCGCCATTCCAGGGAACCCGCCATGA

Upstream 100 bases:

>100_bases
GGCTCAGTCTCCCCGAGGGAGGCTGGGCCTTTTCCTTTTGTCACCCCGATGTTCCAGGGCGCGCCTGGAACTTGCCCGGC
GGCTCCCCTAGACTCGGGGC

Downstream 100 bases:

>100_bases
TCAACAGCGCCGTGCTTGTCCTCAACCGGTACTACCAGCCGGTGCATGTCACCTCGGTGAAGCGGGCGTTCTCGCTCCTG
TACCTGGGGGTGGCCAAGGC

Product: L-seryl-tRNA selenium transferase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MGAPSNSGDGGKNALLRALPSVEQLLRRPSLEPLLSGVPRARAVAALRLAVDRARGRLVASGGPGFEDADVQHALDTLAT
PGLRPVLNATGVVLHTNLGRAPLAASAVARVAEVARGYSNLEYDLDEGERGSRYAPLVGLLRSLTGAEDAVVVNNCAGAV
LLVLAALASGRECVVSRGELVEIGGGFRVPEVMRQSGAKLVEVGTTNRTRLSDYSAALGPESALLVKVHRSNFALVGFTE
EVEVAELSALGRARGVPVFQDLGAGALVPLKGEGLSRELTVAQAVAAGADVVAFSGDKLLGGPQAGVVVGRSVLLARIKA
HPLMRALRVDKLTVAALEATLALYRDGRAEEVPVHRLLAQSPEDLRARAVRLQGLLAGQGVRARVASVEGQVGGGAMPLA
RLPSSACILTLGTPEEFLERLRGGMSPVIGRIADGEVLLDVRCLEEEELQAVADAVAAAIPGNPP

Sequences:

>Translated_465_residues
MGAPSNSGDGGKNALLRALPSVEQLLRRPSLEPLLSGVPRARAVAALRLAVDRARGRLVASGGPGFEDADVQHALDTLAT
PGLRPVLNATGVVLHTNLGRAPLAASAVARVAEVARGYSNLEYDLDEGERGSRYAPLVGLLRSLTGAEDAVVVNNCAGAV
LLVLAALASGRECVVSRGELVEIGGGFRVPEVMRQSGAKLVEVGTTNRTRLSDYSAALGPESALLVKVHRSNFALVGFTE
EVEVAELSALGRARGVPVFQDLGAGALVPLKGEGLSRELTVAQAVAAGADVVAFSGDKLLGGPQAGVVVGRSVLLARIKA
HPLMRALRVDKLTVAALEATLALYRDGRAEEVPVHRLLAQSPEDLRARAVRLQGLLAGQGVRARVASVEGQVGGGAMPLA
RLPSSACILTLGTPEEFLERLRGGMSPVIGRIADGEVLLDVRCLEEEELQAVADAVAAAIPGNPP
>Mature_464_residues
GAPSNSGDGGKNALLRALPSVEQLLRRPSLEPLLSGVPRARAVAALRLAVDRARGRLVASGGPGFEDADVQHALDTLATP
GLRPVLNATGVVLHTNLGRAPLAASAVARVAEVARGYSNLEYDLDEGERGSRYAPLVGLLRSLTGAEDAVVVNNCAGAVL
LVLAALASGRECVVSRGELVEIGGGFRVPEVMRQSGAKLVEVGTTNRTRLSDYSAALGPESALLVKVHRSNFALVGFTEE
VEVAELSALGRARGVPVFQDLGAGALVPLKGEGLSRELTVAQAVAAGADVVAFSGDKLLGGPQAGVVVGRSVLLARIKAH
PLMRALRVDKLTVAALEATLALYRDGRAEEVPVHRLLAQSPEDLRARAVRLQGLLAGQGVRARVASVEGQVGGGAMPLAR
LPSSACILTLGTPEEFLERLRGGMSPVIGRIADGEVLLDVRCLEEEELQAVADAVAAAIPGNPP

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=449, Percent_Identity=49.6659242761693, Blast_Score=345, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 48048; Mature: 47917

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAPSNSGDGGKNALLRALPSVEQLLRRPSLEPLLSGVPRARAVAALRLAVDRARGRLVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHCCEEEE
SGGPGFEDADVQHALDTLATPGLRPVLNATGVVLHTNLGRAPLAASAVARVAEVARGYSN
CCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
LEYDLDEGERGSRYAPLVGLLRSLTGAEDAVVVNNCAGAVLLVLAALASGRECVVSRGEL
CEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHCCCCEEECCCCE
VEIGGGFRVPEVMRQSGAKLVEVGTTNRTRLSDYSAALGPESALLVKVHRSNFALVGFTE
EEECCCCCCHHHHHHCCCEEEEECCCCCCCCCCHHHHCCCCCEEEEEEECCCEEEEEECC
EVEVAELSALGRARGVPVFQDLGAGALVPLKGEGLSRELTVAQAVAAGADVVAFSGDKLL
CHHHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCC
GGPQAGVVVGRSVLLARIKAHPLMRALRVDKLTVAALEATLALYRDGRAEEVPVHRLLAQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHC
SPEDLRARAVRLQGLLAGQGVRARVASVEGQVGGGAMPLARLPSSACILTLGTPEEFLER
CCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHH
LRGGMSPVIGRIADGEVLLDVRCLEEEELQAVADAVAAAIPGNPP
HHCCCCHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GAPSNSGDGGKNALLRALPSVEQLLRRPSLEPLLSGVPRARAVAALRLAVDRARGRLVA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHCCEEEE
SGGPGFEDADVQHALDTLATPGLRPVLNATGVVLHTNLGRAPLAASAVARVAEVARGYSN
CCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
LEYDLDEGERGSRYAPLVGLLRSLTGAEDAVVVNNCAGAVLLVLAALASGRECVVSRGEL
CEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHCCCCEEECCCCE
VEIGGGFRVPEVMRQSGAKLVEVGTTNRTRLSDYSAALGPESALLVKVHRSNFALVGFTE
EEECCCCCCHHHHHHCCCEEEEECCCCCCCCCCHHHHCCCCCEEEEEEECCCEEEEEECC
EVEVAELSALGRARGVPVFQDLGAGALVPLKGEGLSRELTVAQAVAAGADVVAFSGDKLL
CHHHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCC
GGPQAGVVVGRSVLLARIKAHPLMRALRVDKLTVAALEATLALYRDGRAEEVPVHRLLAQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHC
SPEDLRARAVRLQGLLAGQGVRARVASVEGQVGGGAMPLARLPSSACILTLGTPEEFLER
CCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHH
LRGGMSPVIGRIADGEVLLDVRCLEEEELQAVADAVAAAIPGNPP
HHCCCCHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA