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The map label for this gene is arsA [H]

Identifier: 108758691

GI number: 108758691

Start: 4949264

End: 4951231

Strand: Reverse

Name: arsA [H]

Synonym: MXAN_4041

Alternate gene names: 108758691

Gene position: 4951231-4949264 (Counterclockwise)

Preceding gene: 108761709

Following gene: 108761085

Centisome position: 54.17

GC content: 70.58

Gene sequence:

>1968_bases
ATGAGCGACGCGCGAGTACTTCACTTCTTCGGCGGCAAAGGCGGGGTAGGTAAGACCACGCTCGCGGCGGCATATGCGTT
GAGGCTGTCGGAGGATGCGCCCAAGGAGCGGGTGCTGCTCGTGTCGTTGGATCCGGTCCGCTCCCTGTCGGACCTGGTGA
AGAAGAAGCTCCCGGCCAAGGCGACCAAGCTGGTCCCGGGTAAGGGAGACGGCGGCGTGTACGGCCTGGAAGTGGAGCCG
GCGGCGCTGATGAAGCCCTTCCTGGCCTCCTACCTGCCAGCGCTGTCGAAGGCCGCGGCGAAGGGCACGCACGTGTCGGA
AGACGACATGGGCAAGCTGTACCAGCAGGCCGTGCCGGGGCTGGAGGAGTTGGTGGCGCTCTTCCACGTGGTGGACCTGC
TGGAGGGCGAGGAGTTCGACCGCATCGTGGTGGACGCCGCGCCGACCAGCCACACCCTGCGGCTGTTCGACCTGCCGACG
AGCCTGCGCAAGTTCCTGGGCCTGGTGAAGGCCGGTGGGGACAAGACGGAGGCGCCGCCGAAGAAGGGCAAGAAGGCGGC
GGCCGCGGCCGAGGCGCCCGGCTTCCTGGAGCAGGTGGGGCAGAAGGCGGAGAAGCTGCTGGCGCTGCTGAAGGACCCCG
CGCGCACGGCCTTCCACCTGGTGGCGCTGGCGGAGCCGGTGCCCGAGGCGCAGACGCGCATGCTCTTCACCCAGCTTCGC
GAGCGCGGGCTGCCGGTGACGGAGATCGTCGTCAATCAGATCGAGGACAAGGACGGCTGTCCCGCGTGCCAGGGCCGTCG
CGGCCTACAGGCCCCCCACGTCCGCAAGTTCCAGGCACTGGACAAGACGGTGCCGGTGCACCTGCTGGGCCGGCGTGAAG
TGGCGCCGCGCGGGCTGGATGGCCTGGCGCTGTTCGCCAAGGCGTGGGCCGCTGGCAAGGAGACCAAGGCGCTGGAGTTC
GCCGCGGCCGAAGGGCCTCCGGCGCTGGTGCGCGCGCCGTCCATGCCGCCCATCGCCGCGCCGCCGCTGCCGCCCACGCG
GCTCATCTTCTTCGTGGGGCAGGGCGGGGTGGGCAAGAGCTCCTGCGCCGCCGCCGCCGCGGTGACGCTGACGGAGAAGG
AGGGGCCGGTGCTCCTCATCTCCACGGATCCGGCGCACTCGCTGTCGGACGTGCTGCAGAGCCGCCTGACGGACACGGAG
ACGCAGGTGAAGGGCACCAAGGGCCTATACGCTCGCGAGCTGGACATCGCCGGCTGGTTCAATGCCCTGCGCAAGCGGGT
GAAGGAGAAGGCGGAGAAGGCGTTCGAGGGCGCGCCCCGGTCGGGCAGCGAGGTGCCCGCGGATCTGCTCTACCTGCGCA
ACCTTCTGGAGTGCGCGCCGCCGGGCATCGACGAGCTGGCCGCGCTGTCCTGTCTGACGGACGCGCTGGTGCAGGAGCGC
TTCAAGCGCATCGTGGTGGACTCGGCGCCGGTGGTGACGTCCGTGCGCGTGGTGGAAATGGCGGAGACGGCCAAGACGTG
GCTGGGCGCGCTGCACGCGGTGCTGACCAAGCACCGCGCCAAGGGCCTGGCCGAGCTGGCGGACGACATCGCCGGGATGA
TCAAGCACGTGAAGCGCTTCGAGGACGCGCTGGCCTCCCCGAGCGAGGCGCGCTTCGTGGTCGTCACGCGCGGCGAGGAG
CTGGCCGCGGCCCGCACCGAGCGGCTGGTGGAGTACCTGAAGGAGAAGAAGCTCCCCGTGGAGCGGGTGCTCGTCAACCG
CGTGGGCCCCAAGTCCACCTGCGACAAGTGCGAGAGCCGGCGCAAGCTGGAGTTCAACGCGGCGAAGGCCATCGAGAAGA
AGCTGGGCCTGCCCGTGACCATGGCGCCGGCCCTGGGCCGTCACCCGGCGGGTCTGCGCGAGCTGAAGGCCTTCCGCACG
GCGTGGTACGCGCTGTCGCCGCCGGCCGCCAAGACCAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
ATGTTCCACGCCTCGGGCAACTCCAGCGGCGCCAATCTATTCGGGCGCCCCGGAGTGTGCATCGGGTGCCGCGGGGGGGC
ACAAGGAAGGCCACAACGCA

Downstream 100 bases:

>100_bases
GGTCCAGGCTCGTCGTGAATCGAGCCAAGGAAGCCCTGCCGGGCTTCGTTCCACCCGGCGGGAGTGTCCTGGCTGTTGTG
CAGAAGTAGAGGGGGCCGCC

Product: arsenical pump-driving ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 655; Mature: 654

Protein sequence:

>655_residues
MSDARVLHFFGGKGGVGKTTLAAAYALRLSEDAPKERVLLVSLDPVRSLSDLVKKKLPAKATKLVPGKGDGGVYGLEVEP
AALMKPFLASYLPALSKAAAKGTHVSEDDMGKLYQQAVPGLEELVALFHVVDLLEGEEFDRIVVDAAPTSHTLRLFDLPT
SLRKFLGLVKAGGDKTEAPPKKGKKAAAAAEAPGFLEQVGQKAEKLLALLKDPARTAFHLVALAEPVPEAQTRMLFTQLR
ERGLPVTEIVVNQIEDKDGCPACQGRRGLQAPHVRKFQALDKTVPVHLLGRREVAPRGLDGLALFAKAWAAGKETKALEF
AAAEGPPALVRAPSMPPIAAPPLPPTRLIFFVGQGGVGKSSCAAAAAVTLTEKEGPVLLISTDPAHSLSDVLQSRLTDTE
TQVKGTKGLYARELDIAGWFNALRKRVKEKAEKAFEGAPRSGSEVPADLLYLRNLLECAPPGIDELAALSCLTDALVQER
FKRIVVDSAPVVTSVRVVEMAETAKTWLGALHAVLTKHRAKGLAELADDIAGMIKHVKRFEDALASPSEARFVVVTRGEE
LAAARTERLVEYLKEKKLPVERVLVNRVGPKSTCDKCESRRKLEFNAAKAIEKKLGLPVTMAPALGRHPAGLRELKAFRT
AWYALSPPAAKTKAA

Sequences:

>Translated_655_residues
MSDARVLHFFGGKGGVGKTTLAAAYALRLSEDAPKERVLLVSLDPVRSLSDLVKKKLPAKATKLVPGKGDGGVYGLEVEP
AALMKPFLASYLPALSKAAAKGTHVSEDDMGKLYQQAVPGLEELVALFHVVDLLEGEEFDRIVVDAAPTSHTLRLFDLPT
SLRKFLGLVKAGGDKTEAPPKKGKKAAAAAEAPGFLEQVGQKAEKLLALLKDPARTAFHLVALAEPVPEAQTRMLFTQLR
ERGLPVTEIVVNQIEDKDGCPACQGRRGLQAPHVRKFQALDKTVPVHLLGRREVAPRGLDGLALFAKAWAAGKETKALEF
AAAEGPPALVRAPSMPPIAAPPLPPTRLIFFVGQGGVGKSSCAAAAAVTLTEKEGPVLLISTDPAHSLSDVLQSRLTDTE
TQVKGTKGLYARELDIAGWFNALRKRVKEKAEKAFEGAPRSGSEVPADLLYLRNLLECAPPGIDELAALSCLTDALVQER
FKRIVVDSAPVVTSVRVVEMAETAKTWLGALHAVLTKHRAKGLAELADDIAGMIKHVKRFEDALASPSEARFVVVTRGEE
LAAARTERLVEYLKEKKLPVERVLVNRVGPKSTCDKCESRRKLEFNAAKAIEKKLGLPVTMAPALGRHPAGLRELKAFRT
AWYALSPPAAKTKAA
>Mature_654_residues
SDARVLHFFGGKGGVGKTTLAAAYALRLSEDAPKERVLLVSLDPVRSLSDLVKKKLPAKATKLVPGKGDGGVYGLEVEPA
ALMKPFLASYLPALSKAAAKGTHVSEDDMGKLYQQAVPGLEELVALFHVVDLLEGEEFDRIVVDAAPTSHTLRLFDLPTS
LRKFLGLVKAGGDKTEAPPKKGKKAAAAAEAPGFLEQVGQKAEKLLALLKDPARTAFHLVALAEPVPEAQTRMLFTQLRE
RGLPVTEIVVNQIEDKDGCPACQGRRGLQAPHVRKFQALDKTVPVHLLGRREVAPRGLDGLALFAKAWAAGKETKALEFA
AAEGPPALVRAPSMPPIAAPPLPPTRLIFFVGQGGVGKSSCAAAAAVTLTEKEGPVLLISTDPAHSLSDVLQSRLTDTET
QVKGTKGLYARELDIAGWFNALRKRVKEKAEKAFEGAPRSGSEVPADLLYLRNLLECAPPGIDELAALSCLTDALVQERF
KRIVVDSAPVVTSVRVVEMAETAKTWLGALHAVLTKHRAKGLAELADDIAGMIKHVKRFEDALASPSEARFVVVTRGEEL
AAARTERLVEYLKEKKLPVERVLVNRVGPKSTCDKCESRRKLEFNAAKAIEKKLGLPVTMAPALGRHPAGLRELKAFRTA
WYALSPPAAKTKAA

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=302, Percent_Identity=26.158940397351, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17557003, Length=281, Percent_Identity=27.0462633451957, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320103, Length=307, Percent_Identity=26.7100977198697, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24586297, Length=297, Percent_Identity=26.9360269360269, Blast_Score=96, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016300
- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 70254; Mature: 70123

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDARVLHFFGGKGGVGKTTLAAAYALRLSEDAPKERVLLVSLDPVRSLSDLVKKKLPAK
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCH
ATKLVPGKGDGGVYGLEVEPAALMKPFLASYLPALSKAAAKGTHVSEDDMGKLYQQAVPG
HHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
LEELVALFHVVDLLEGEEFDRIVVDAAPTSHTLRLFDLPTSLRKFLGLVKAGGDKTEAPP
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCC
KKGKKAAAAAEAPGFLEQVGQKAEKLLALLKDPARTAFHLVALAEPVPEAQTRMLFTQLR
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ERGLPVTEIVVNQIEDKDGCPACQGRRGLQAPHVRKFQALDKTVPVHLLGRREVAPRGLD
HCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCH
GLALFAKAWAAGKETKALEFAAAEGPPALVRAPSMPPIAAPPLPPTRLIFFVGQGGVGKS
HHHHHHHHHHCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCH
SCAAAAAVTLTEKEGPVLLISTDPAHSLSDVLQSRLTDTETQVKGTKGLYARELDIAGWF
HHHHHHEEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHH
NALRKRVKEKAEKAFEGAPRSGSEVPADLLYLRNLLECAPPGIDELAALSCLTDALVQER
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FKRIVVDSAPVVTSVRVVEMAETAKTWLGALHAVLTKHRAKGLAELADDIAGMIKHVKRF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDALASPSEARFVVVTRGEELAAARTERLVEYLKEKKLPVERVLVNRVGPKSTCDKCESR
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHC
RKLEFNAAKAIEKKLGLPVTMAPALGRHPAGLRELKAFRTAWYALSPPAAKTKAA
CCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SDARVLHFFGGKGGVGKTTLAAAYALRLSEDAPKERVLLVSLDPVRSLSDLVKKKLPAK
CCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCH
ATKLVPGKGDGGVYGLEVEPAALMKPFLASYLPALSKAAAKGTHVSEDDMGKLYQQAVPG
HHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
LEELVALFHVVDLLEGEEFDRIVVDAAPTSHTLRLFDLPTSLRKFLGLVKAGGDKTEAPP
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCC
KKGKKAAAAAEAPGFLEQVGQKAEKLLALLKDPARTAFHLVALAEPVPEAQTRMLFTQLR
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ERGLPVTEIVVNQIEDKDGCPACQGRRGLQAPHVRKFQALDKTVPVHLLGRREVAPRGLD
HCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCH
GLALFAKAWAAGKETKALEFAAAEGPPALVRAPSMPPIAAPPLPPTRLIFFVGQGGVGKS
HHHHHHHHHHCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCH
SCAAAAAVTLTEKEGPVLLISTDPAHSLSDVLQSRLTDTETQVKGTKGLYARELDIAGWF
HHHHHHEEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHH
NALRKRVKEKAEKAFEGAPRSGSEVPADLLYLRNLLECAPPGIDELAALSCLTDALVQER
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FKRIVVDSAPVVTSVRVVEMAETAKTWLGALHAVLTKHRAKGLAELADDIAGMIKHVKRF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDALASPSEARFVVVTRGEELAAARTERLVEYLKEKKLPVERVLVNRVGPKSTCDKCESR
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHC
RKLEFNAAKAIEKKLGLPVTMAPALGRHPAGLRELKAFRTAWYALSPPAAKTKAA
CCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9847077; 11016950 [H]