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The map label for this gene is 108758657

Identifier: 108758657

GI number: 108758657

Start: 163224

End: 164681

Strand: Reverse

Name: 108758657

Synonym: MXAN_0140

Alternate gene names: NA

Gene position: 164681-163224 (Counterclockwise)

Preceding gene: 108757057

Following gene: 108764096

Centisome position: 1.8

GC content: 72.15

Gene sequence:

>1458_bases
ATGACCGCCAGGCTGGACCCGTTCGTCCCCGCAGCTTCGCCGCAGGCCGTGCCCACGCCCGAGCTCACCGCTCCGTCGTC
AGACGCGGCCGCGAAGCGTGAAGCCCGCCGGCTCGCGCACGAAGCGTTGCTCGTCCGCGCGAAGGCCATCGACGAAGCGG
GCGGCGCCGACGACTGGGTGCAGGCGCAGCTCGTCTCCAAGGGCCTCGCGGTGGAGGACCTGGACTTCTCCAGCGCCTCC
GAGAAGGACAAGAAGGCCTGGAAGGAGAAGAAGAAGGCCGAGGCCACCGAGCGCCGCGCGCTGAAGCGTCAGGCGCACGA
GGCGTGGAAGGCCACGCACGTGGGCCACCTGGGCGCGGGCGTGCACTGGGCGGAGGACCGCCTGGCCGACGCGTTCGACG
TGCCCCACCGCGAGGAGCGCGCCCGGGCCAACGGCCTGACGGAGCTGGACTCGGCGGAGGCGCTGGCCAAGGCGCTGGGG
CTGAGCGTGTCCAAGCTGCGCTGGTTCGCGTTCCACCGCGAGGTGGACACGGCCACGCACTACGTGAGCTGGACGATTCC
GAAGCGGGACGGCAGCAAGCGCACGATTACGTCCCCCAAGCCTGAGCTGAAGGCAGCGCAGCGCTGGGTGCTGTCCAACG
TCGTGGAGCGGCTGCCGGTGCACGGCGCGGCGCACGGCTTCGTGGCGGGACGCTCCATCCTCACCAACGCGCTGGCCCAC
CAGGGCGCGGACGTGGTGGTGAAGGTGGACCTCAAGGACTTCTTCCCCTCCGTCACCTGGCGCCGGGTGAAGGGCCTGTT
GCGCAAGGGCGGCCTGCCGGAGGGCACGTCCACGCTGCTGTCGCTGCTCTCCACGGAAGCGCCGCGGGAGGCGGTGCAGT
TCCGGGGCAAGCTGCTGCACGTGGCCAAGGGCCCGCGCGCGCTGCCCCAGGGCGCGCCCACGTCGCCGGGCATCACCAAC
GCGCTGTGCCTGAAGCTGGACAAGCGGCTGTCCGCGCTCGCGAAGCGGCTGGGCTTCACGTACACGCGCTACGCGGACGA
CCTGACCTTCTCGTGGACGAAGGCGAAGCAGCCCAAGCCGCGGCGGACGCAGCGTCCCCCGGTGGCGGTGCTGCTGTCTC
GCGTGCAGGAAGTGGTGGAGGCGGAGGGCTTCCGCGTGCACCCGGACAAGACGCGCGTGGCGCGCAAGGGCACGCGGCAG
CGGGTGACGGGGCTGGTCGTGAATGCGGCGGGCAAGGACGCGCCGGCGGCCCGAGTCCCGCGCGACGTGGTGCGCCAGCT
CCGCGCCGCCATCCACAACCGGAAGAAGGGCAAGCCGGGCCGCGAGGGCGAGTCGCTGGAGCAGCTCAAGGGCATGGCCG
CCTTCATCCACATGACGGACCCGGCCAAGGGCCGCGCCTTCCTGGCTCAGCTCACGGAGCTGGAGTCCACGGCGAGCGCG
GCTCCGCAGGCGGAGTGA

Upstream 100 bases:

>100_bases
GCTACCGTGCCCCAGGTAAGATGGTGGTGCTTTCCCGGCCTCCCTCGACTGCTCGCGCCATGTCCCGTCTTCCATCGCCG
CGCCCGCCCAAGGTGCAGAC

Downstream 100 bases:

>100_bases
CGCTCAGCGCGCGTCCGTCGCCGAGGTGCCGCGCGCCAGCAACGCGGCATTGAGGAAGTCCGTCAGCCGGCGCGGGTACG
CCTCTGGCTCGGTGGCGCTG

Product: RNA-directed DNA polymerase domain-containing protein

Products: NA

Alternate protein names: Mx162-RT; Reverse transcriptase [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTARLDPFVPAASPQAVPTPELTAPSSDAAAKREARRLAHEALLVRAKAIDEAGGADDWVQAQLVSKGLAVEDLDFSSAS
EKDKKAWKEKKKAEATERRALKRQAHEAWKATHVGHLGAGVHWAEDRLADAFDVPHREERARANGLTELDSAEALAKALG
LSVSKLRWFAFHREVDTATHYVSWTIPKRDGSKRTITSPKPELKAAQRWVLSNVVERLPVHGAAHGFVAGRSILTNALAH
QGADVVVKVDLKDFFPSVTWRRVKGLLRKGGLPEGTSTLLSLLSTEAPREAVQFRGKLLHVAKGPRALPQGAPTSPGITN
ALCLKLDKRLSALAKRLGFTYTRYADDLTFSWTKAKQPKPRRTQRPPVAVLLSRVQEVVEAEGFRVHPDKTRVARKGTRQ
RVTGLVVNAAGKDAPAARVPRDVVRQLRAAIHNRKKGKPGREGESLEQLKGMAAFIHMTDPAKGRAFLAQLTELESTASA
APQAE

Sequences:

>Translated_485_residues
MTARLDPFVPAASPQAVPTPELTAPSSDAAAKREARRLAHEALLVRAKAIDEAGGADDWVQAQLVSKGLAVEDLDFSSAS
EKDKKAWKEKKKAEATERRALKRQAHEAWKATHVGHLGAGVHWAEDRLADAFDVPHREERARANGLTELDSAEALAKALG
LSVSKLRWFAFHREVDTATHYVSWTIPKRDGSKRTITSPKPELKAAQRWVLSNVVERLPVHGAAHGFVAGRSILTNALAH
QGADVVVKVDLKDFFPSVTWRRVKGLLRKGGLPEGTSTLLSLLSTEAPREAVQFRGKLLHVAKGPRALPQGAPTSPGITN
ALCLKLDKRLSALAKRLGFTYTRYADDLTFSWTKAKQPKPRRTQRPPVAVLLSRVQEVVEAEGFRVHPDKTRVARKGTRQ
RVTGLVVNAAGKDAPAARVPRDVVRQLRAAIHNRKKGKPGREGESLEQLKGMAAFIHMTDPAKGRAFLAQLTELESTASA
APQAE
>Mature_484_residues
TARLDPFVPAASPQAVPTPELTAPSSDAAAKREARRLAHEALLVRAKAIDEAGGADDWVQAQLVSKGLAVEDLDFSSASE
KDKKAWKEKKKAEATERRALKRQAHEAWKATHVGHLGAGVHWAEDRLADAFDVPHREERARANGLTELDSAEALAKALGL
SVSKLRWFAFHREVDTATHYVSWTIPKRDGSKRTITSPKPELKAAQRWVLSNVVERLPVHGAAHGFVAGRSILTNALAHQ
GADVVVKVDLKDFFPSVTWRRVKGLLRKGGLPEGTSTLLSLLSTEAPREAVQFRGKLLHVAKGPRALPQGAPTSPGITNA
LCLKLDKRLSALAKRLGFTYTRYADDLTFSWTKAKQPKPRRTQRPPVAVLLSRVQEVVEAEGFRVHPDKTRVARKGTRQR
VTGLVVNAAGKDAPAARVPRDVVRQLRAAIHNRKKGKPGREGESLEQLKGMAAFIHMTDPAKGRAFLAQLTELESTASAA
PQAE

Specific function: Participates in the synthesis of a msDNA (a branched RNA linked by a 2',5'-phosphodiester linkage to a single-stranded DNA) of unknown function. The retron transcript serves as primer and template to the reaction, and codes for the RT [H]

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000123
- InterPro:   IPR000477 [H]

Pfam domain/function: PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 52959; Mature: 52828

Theoretical pI: Translated: 10.95; Mature: 10.95

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARLDPFVPAASPQAVPTPELTAPSSDAAAKREARRLAHEALLVRAKAIDEAGGADDWV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
QAQLVSKGLAVEDLDFSSASEKDKKAWKEKKKAEATERRALKRQAHEAWKATHVGHLGAG
HHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VHWAEDRLADAFDVPHREERARANGLTELDSAEALAKALGLSVSKLRWFAFHREVDTATH
CCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHE
YVSWTIPKRDGSKRTITSPKPELKAAQRWVLSNVVERLPVHGAAHGFVAGRSILTNALAH
EEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
QGADVVVKVDLKDFFPSVTWRRVKGLLRKGGLPEGTSTLLSLLSTEAPREAVQFRGKLLH
CCCCEEEEEEHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHE
VAKGPRALPQGAPTSPGITNALCLKLDKRLSALAKRLGFTYTRYADDLTFSWTKAKQPKP
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCCCC
RRTQRPPVAVLLSRVQEVVEAEGFRVHPDKTRVARKGTRQRVTGLVVNAAGKDAPAARVP
CCCCCCHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHEEEEECCCCCCCHHCCC
RDVVRQLRAAIHNRKKGKPGREGESLEQLKGMAAFIHMTDPAKGRAFLAQLTELESTASA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHCC
APQAE
CCCCC
>Mature Secondary Structure 
TARLDPFVPAASPQAVPTPELTAPSSDAAAKREARRLAHEALLVRAKAIDEAGGADDWV
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
QAQLVSKGLAVEDLDFSSASEKDKKAWKEKKKAEATERRALKRQAHEAWKATHVGHLGAG
HHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VHWAEDRLADAFDVPHREERARANGLTELDSAEALAKALGLSVSKLRWFAFHREVDTATH
CCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHE
YVSWTIPKRDGSKRTITSPKPELKAAQRWVLSNVVERLPVHGAAHGFVAGRSILTNALAH
EEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
QGADVVVKVDLKDFFPSVTWRRVKGLLRKGGLPEGTSTLLSLLSTEAPREAVQFRGKLLH
CCCCEEEEEEHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHE
VAKGPRALPQGAPTSPGITNALCLKLDKRLSALAKRLGFTYTRYADDLTFSWTKAKQPKP
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCCCC
RRTQRPPVAVLLSRVQEVVEAEGFRVHPDKTRVARKGTRQRVTGLVVNAAGKDAPAARVP
CCCCCCHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHEEEEECCCCCCCHHCCC
RDVVRQLRAAIHNRKKGKPGREGESLEQLKGMAAFIHMTDPAKGRAFLAQLTELESTASA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHCC
APQAE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2465092; 2465091 [H]