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The map label for this gene is kinA [H]

Identifier: 108758532

GI number: 108758532

Start: 707603

End: 709774

Strand: Direct

Name: kinA [H]

Synonym: MXAN_0612

Alternate gene names: 108758532

Gene position: 707603-709774 (Clockwise)

Preceding gene: 108757538

Following gene: 108760215

Centisome position: 7.74

GC content: 71.59

Gene sequence:

>2172_bases
GTGGCAGACGAGCAACGGGACGCGGCGGTCATGGACGCTCCCGGGAAGGCTTCAGGGACGGCTCCCGCCGACATGGCGTG
TGACCTGCTCCCCCCCATGAAGTCGCAGGCGTCACACGCTGGGAGCCAGGTGGAGTCCGAGCGCTTCCGGCACCTGTCCG
AGCTGCTGCACGAGGTGGTGTTCCAGCTCGACGCGCAGGGGCGGCTCGCGGTGCTGGGCGGTGCCTGGGAGCGGCTCACC
GGGACGCCCGTGTCCGCGTGGCGGGGCCGCGCGCTCTTGGAGGCCATCCACCCGGAGGACCGCGAGCGCGCCCAGGCGTT
GCTGGCGTACACGCCCGGCATCCCCGTTTCGCGCCAGGAAGTACGCGTGGACACGGGCGGCGGCCATGGCGTCCGTTGGG
TGGAGCTGTCCGCCCGGGCCCTGGCCACCGTGCCGGGCGAGGTGATGGGGACGCTCCTGGACGTGACGTCGCGACGCACG
GCGGAGGAGGCCGTCACCACCCGCGAGCGCTACCTGGACGCCATGGTGCAGGTGCAGCGGCGGATGATGGGGCACGATTT
GCCGGACGACCTGTACGGCGCCGTCGTCGAGCCGTTGGGCCACGTGTCCGCCGCCAGCCGCGTCTACGTCTTCGAGATGC
ACTTCGCCGAGGACGGCACGCTGCTGGCGTCGCAGCGCGCGGAGTGGTGCGCGCCGGGGATTCCTCCCAACCTGGAGGAC
CCCAACATGCACGGCCTGCCCTTCGACGCGGCCCTGCGGCCCCATCAGTCCGAACAGTTGCAGCGCGGCGAGCCGGTGCA
GGGCCAGCCGCGAGACTTCTCGGAGCTGCTGGCGCCCATGCTGGAGGCGCAGGGCGTCCGCTCCGTGCTGCTGCTGCCCA
TGCACGTCCACGGGCAGCTCTTCGGCGTCATCGGCTTCGACAACTGCCGCGAACCCGAGTCCTGGGGCCCCATCGAGGTG
AACCTGTTGTCGGGCGCGGCGGGCGCGCTGTCCCTGGCGCTGGAGCAGCGCACGGCCAACGCGCTGCGCATGCGCACGGA
GACGACGCTGCGGCGCACCGAGGCCGGCGTCCACCTGCTCATCGAGGCCTTCCCGGACCCGGTGCTGGTGCACGTGGGCG
ACGGCGTGCTGCTCTCCGTCAACCCGGCGCTGGTGCAGTACCTGGGCTTCCGCGACGCCTCGGAGTTGGTGGGCCGCCAC
ATGCTGGACCTGGTCCGCCCCGAGGACCGGGGGGCCGCGCAGCTCCACCTGAGCCAGGCGCTGGAGGGCAAGAGCGCGGC
GCGCGTGGTGGAGATGCCGCTGGTGCGCAGCGACGGCGAGGTGGTGGTGGCGGACCTGGTGACGCTGGCCGTGGTGCTGG
ACGGCTCGCCCGCGCGCATCACCGTGGCGCGCGACTTCACCGAGCGCAAGCGCACCCAGGCGCAGCTCATGCTGACCGAC
CGCATGGCCTCCATGGGCCTCCTGGCCGCCGGCATCGCCCACGAGCTCAACAACCCCCTGGCCTACGTGCTGTCCAACCT
GGACTTCCTCCACAGCGCCGTGGGCGGCGTGCGTCCACGGATGCTCTCCCCGGAGGACATGGTGGAGCTGCGGCAGGTGC
TCGACGACGCCCGTGAGGGTGCCGAGCGCATGCGCCAGATTGTCCGCCAACTGCGCGTCTTCTCCCGCGTGGAGGACGGC
AAGGAAGAGTCGGTGGACGTCCACGCGGTGCTCGAATCCGTGACGCAGATGGCCGCCAGCGTGGTGCGCGCCCGCGCCCG
GCTGGTGAAGGACTACGGTGAGGTGCCGTTCGTCCGTGGCAACGAGGGCAAGCTGTTCCAGGTGTTCCTCAACCTCCTCA
TCAACGCCGCGCACGCCATCGAAGAGGGCGATTCGGAGGCGAACGAAATTCGCCTCACCACCCGCACGGAGGTGGGCGGC
CGGGTGATGGTGGTGGTGAGCGACACGGGCCAGGGCATCCCCCCGGAGCACCTGCGCCGCATCTTCGACCCCTTCTTCAC
CACCAAGTCCTCCGGCCTGGGCACCGGCCTGGGGCTGTCCATCTGTGACACGATTGTGACGGCGCTGGGCGGCCACATCT
CCGTGGAGTCGTCGATAGGGGCCGGCACCACCTTCCGCGTGGCGCTCAGCGCCGCGCCGCCCAAGGCCCCGGCGAACCGG
CCGGGCGCGTGA

Upstream 100 bases:

>100_bases
CCACGGGAGGGGAACCGCAGGGTCTGGAATCGTTCCCGGCAGCCGTAGGTGCTGTCAGGGCTCCAGCCCCTCTCCGATGA
GGCGCTAGGGAGGCCAGCAC

Downstream 100 bases:

>100_bases
GCGCTGAGACGGCCGGTGTCACCTCCGGCCCTCGCGCGGACTGTAGCCCTCTCGACGGCTCGTTCTTCCGGTACTGCGCG
CCCGCCCTGAAGCGTTATCC

Product: sensory box histidine kinase

Products: NA

Alternate protein names: Stage II sporulation protein F; Stage II sporulation protein J [H]

Number of amino acids: Translated: 723; Mature: 722

Protein sequence:

>723_residues
MADEQRDAAVMDAPGKASGTAPADMACDLLPPMKSQASHAGSQVESERFRHLSELLHEVVFQLDAQGRLAVLGGAWERLT
GTPVSAWRGRALLEAIHPEDRERAQALLAYTPGIPVSRQEVRVDTGGGHGVRWVELSARALATVPGEVMGTLLDVTSRRT
AEEAVTTRERYLDAMVQVQRRMMGHDLPDDLYGAVVEPLGHVSAASRVYVFEMHFAEDGTLLASQRAEWCAPGIPPNLED
PNMHGLPFDAALRPHQSEQLQRGEPVQGQPRDFSELLAPMLEAQGVRSVLLLPMHVHGQLFGVIGFDNCREPESWGPIEV
NLLSGAAGALSLALEQRTANALRMRTETTLRRTEAGVHLLIEAFPDPVLVHVGDGVLLSVNPALVQYLGFRDASELVGRH
MLDLVRPEDRGAAQLHLSQALEGKSAARVVEMPLVRSDGEVVVADLVTLAVVLDGSPARITVARDFTERKRTQAQLMLTD
RMASMGLLAAGIAHELNNPLAYVLSNLDFLHSAVGGVRPRMLSPEDMVELRQVLDDAREGAERMRQIVRQLRVFSRVEDG
KEESVDVHAVLESVTQMAASVVRARARLVKDYGEVPFVRGNEGKLFQVFLNLLINAAHAIEEGDSEANEIRLTTRTEVGG
RVMVVVSDTGQGIPPEHLRRIFDPFFTTKSSGLGTGLGLSICDTIVTALGGHISVESSIGAGTTFRVALSAAPPKAPANR
PGA

Sequences:

>Translated_723_residues
MADEQRDAAVMDAPGKASGTAPADMACDLLPPMKSQASHAGSQVESERFRHLSELLHEVVFQLDAQGRLAVLGGAWERLT
GTPVSAWRGRALLEAIHPEDRERAQALLAYTPGIPVSRQEVRVDTGGGHGVRWVELSARALATVPGEVMGTLLDVTSRRT
AEEAVTTRERYLDAMVQVQRRMMGHDLPDDLYGAVVEPLGHVSAASRVYVFEMHFAEDGTLLASQRAEWCAPGIPPNLED
PNMHGLPFDAALRPHQSEQLQRGEPVQGQPRDFSELLAPMLEAQGVRSVLLLPMHVHGQLFGVIGFDNCREPESWGPIEV
NLLSGAAGALSLALEQRTANALRMRTETTLRRTEAGVHLLIEAFPDPVLVHVGDGVLLSVNPALVQYLGFRDASELVGRH
MLDLVRPEDRGAAQLHLSQALEGKSAARVVEMPLVRSDGEVVVADLVTLAVVLDGSPARITVARDFTERKRTQAQLMLTD
RMASMGLLAAGIAHELNNPLAYVLSNLDFLHSAVGGVRPRMLSPEDMVELRQVLDDAREGAERMRQIVRQLRVFSRVEDG
KEESVDVHAVLESVTQMAASVVRARARLVKDYGEVPFVRGNEGKLFQVFLNLLINAAHAIEEGDSEANEIRLTTRTEVGG
RVMVVVSDTGQGIPPEHLRRIFDPFFTTKSSGLGTGLGLSICDTIVTALGGHISVESSIGAGTTFRVALSAAPPKAPANR
PGA
>Mature_722_residues
ADEQRDAAVMDAPGKASGTAPADMACDLLPPMKSQASHAGSQVESERFRHLSELLHEVVFQLDAQGRLAVLGGAWERLTG
TPVSAWRGRALLEAIHPEDRERAQALLAYTPGIPVSRQEVRVDTGGGHGVRWVELSARALATVPGEVMGTLLDVTSRRTA
EEAVTTRERYLDAMVQVQRRMMGHDLPDDLYGAVVEPLGHVSAASRVYVFEMHFAEDGTLLASQRAEWCAPGIPPNLEDP
NMHGLPFDAALRPHQSEQLQRGEPVQGQPRDFSELLAPMLEAQGVRSVLLLPMHVHGQLFGVIGFDNCREPESWGPIEVN
LLSGAAGALSLALEQRTANALRMRTETTLRRTEAGVHLLIEAFPDPVLVHVGDGVLLSVNPALVQYLGFRDASELVGRHM
LDLVRPEDRGAAQLHLSQALEGKSAARVVEMPLVRSDGEVVVADLVTLAVVLDGSPARITVARDFTERKRTQAQLMLTDR
MASMGLLAAGIAHELNNPLAYVLSNLDFLHSAVGGVRPRMLSPEDMVELRQVLDDAREGAERMRQIVRQLRVFSRVEDGK
EESVDVHAVLESVTQMAASVVRARARLVKDYGEVPFVRGNEGKLFQVFLNLLINAAHAIEEGDSEANEIRLTTRTEVGGR
VMVVVSDTGQGIPPEHLRRIFDPFFTTKSSGLGTGLGLSICDTIVTALGGHISVESSIGAGTTFRVALSAAPPKAPANRP
GA

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=376, Percent_Identity=28.7234042553192, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1790436, Length=269, Percent_Identity=30.1115241635688, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786600, Length=361, Percent_Identity=26.0387811634349, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=27.4900398406374, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=29.957805907173, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=404, Percent_Identity=22.5247524752475, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790300, Length=253, Percent_Identity=29.6442687747036, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78276; Mature: 78145

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEQRDAAVMDAPGKASGTAPADMACDLLPPMKSQASHAGSQVESERFRHLSELLHEVV
CCCCCCCCEEECCCCCCCCCCCHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
FQLDAQGRLAVLGGAWERLTGTPVSAWRGRALLEAIHPEDRERAQALLAYTPGIPVSRQE
HHCCCCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHEEHEECCCCCCCCCE
VRVDTGGGHGVRWVELSARALATVPGEVMGTLLDVTSRRTAEEAVTTRERYLDAMVQVQR
EEEECCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMMGHDLPDDLYGAVVEPLGHVSAASRVYVFEMHFAEDGTLLASQRAEWCAPGIPPNLED
HHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCEEHHCCHHHCCCCCCCCCCC
PNMHGLPFDAALRPHQSEQLQRGEPVQGQPRDFSELLAPMLEAQGVRSVLLLPMHVHGQL
CCCCCCCCHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCEE
FGVIGFDNCREPESWGPIEVNLLSGAAGALSLALEQRTANALRMRTETTLRRTEAGVHLL
EEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IEAFPDPVLVHVGDGVLLSVNPALVQYLGFRDASELVGRHMLDLVRPEDRGAAQLHLSQA
EECCCCCEEEEECCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LEGKSAARVVEMPLVRSDGEVVVADLVTLAVVLDGSPARITVARDFTERKRTQAQLMLTD
HCCCHHHHHHCCCEECCCCCEEHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHHH
RMASMGLLAAGIAHELNNPLAYVLSNLDFLHSAVGGVRPRMLSPEDMVELRQVLDDAREG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
AERMRQIVRQLRVFSRVEDGKEESVDVHAVLESVTQMAASVVRARARLVKDYGEVPFVRG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NEGKLFQVFLNLLINAAHAIEEGDSEANEIRLTTRTEVGGRVMVVVSDTGQGIPPEHLRR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCHHHHHH
IFDPFFTTKSSGLGTGLGLSICDTIVTALGGHISVESSIGAGTTFRVALSAAPPKAPANR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCC
PGA
CCC
>Mature Secondary Structure 
ADEQRDAAVMDAPGKASGTAPADMACDLLPPMKSQASHAGSQVESERFRHLSELLHEVV
CCCCCCCEEECCCCCCCCCCCHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
FQLDAQGRLAVLGGAWERLTGTPVSAWRGRALLEAIHPEDRERAQALLAYTPGIPVSRQE
HHCCCCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHEEHEECCCCCCCCCE
VRVDTGGGHGVRWVELSARALATVPGEVMGTLLDVTSRRTAEEAVTTRERYLDAMVQVQR
EEEECCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMMGHDLPDDLYGAVVEPLGHVSAASRVYVFEMHFAEDGTLLASQRAEWCAPGIPPNLED
HHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCEEHHCCHHHCCCCCCCCCCC
PNMHGLPFDAALRPHQSEQLQRGEPVQGQPRDFSELLAPMLEAQGVRSVLLLPMHVHGQL
CCCCCCCCHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCEE
FGVIGFDNCREPESWGPIEVNLLSGAAGALSLALEQRTANALRMRTETTLRRTEAGVHLL
EEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IEAFPDPVLVHVGDGVLLSVNPALVQYLGFRDASELVGRHMLDLVRPEDRGAAQLHLSQA
EECCCCCEEEEECCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LEGKSAARVVEMPLVRSDGEVVVADLVTLAVVLDGSPARITVARDFTERKRTQAQLMLTD
HCCCHHHHHHCCCEECCCCCEEHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHHH
RMASMGLLAAGIAHELNNPLAYVLSNLDFLHSAVGGVRPRMLSPEDMVELRQVLDDAREG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
AERMRQIVRQLRVFSRVEDGKEESVDVHAVLESVTQMAASVVRARARLVKDYGEVPFVRG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NEGKLFQVFLNLLINAAHAIEEGDSEANEIRLTTRTEVGGRVMVVVSDTGQGIPPEHLRR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCHHHHHH
IFDPFFTTKSSGLGTGLGLSICDTIVTALGGHISVESSIGAGTTFRVALSAAPPKAPANR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCC
PGA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104615; 2509430; 9384377 [H]