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The map label for this gene is mltD [H]

Identifier: 108758438

GI number: 108758438

Start: 7053609

End: 7055639

Strand: Direct

Name: mltD [H]

Synonym: MXAN_5690

Alternate gene names: 108758438

Gene position: 7053609-7055639 (Clockwise)

Preceding gene: 108758850

Following gene: 108757350

Centisome position: 77.17

GC content: 68.93

Gene sequence:

>2031_bases
ATGCCGCCTCTACCTCTGCTCCTGCTCGCCCTGGCCTCAGCCCCTGCCTCGGGGCTCACCCCACCGCCCGTGGGGCCCGT
TCCTGCCAAGGCTCAGGTGGTGGAATCCGAGGGTGCGCAGGCACCCGCAGCGCAGTCTCCGGCCGAGAAGGAACCAACGG
CCGCCACGGAACCTGGCGCCGCGGATACCGGGACCGATGCTGTCGATGAGCCCGGTTTGGAGCCGCTGGAGCCCGGCACG
CCGATGGTGGCCGAGGACGCCTCCGAGCAAGGCGAGGCCACGCGCGACGCGGTTGAGTCCGAGTCCGCTGAGTTGGAGGA
ACTGCGTGCACTGGAAGGCGCCGCGCTGGACCCGGCGTCGCGCTCCACCGCGGAGGTGATGCAGTCGCTGCGGCGGCTCG
GGGTCGCCAACCCGCTGCGGATGCGCATGCTGGACGCGCTCGACGAGCACACCTTCCGCGAGGACGAAGAGCTGCCGGAG
ATTCCGCTCATCACGGACCTGGCCACTTTCGACGTGGGGCAGATTCAGGACCGTTACGACATCCCAGTGGAGATGCAGCC
GCTGGTGGCCCAGTACGTCCAGTTCTTCCAGGGGCCCGGGCGACGCTGGTTCCGCAAGTGGATGTCGCGCGCGGCCCGGT
ACGTGCCGGTGATGCACCCCATCCTGGAGCAGTACGGCCTGCCGAAGGACACGGTGTACCTGGCGATGATTGAGAGCGGC
TTCTCGGCGCATGCCTATTCGTGGGCGCACGCGGCGGGGCCGTGGCAGTTCATCTCCAGCACTGGCAAGCAGTACGGGCT
GAAGCAGGACTTCTGGGTGGACGAGCGGCGGGACCCCATCAAGGCCACCCACGCCGCGGCGTCCTATCTGAAGGACCTCA
AGCGCGAGCTGGGGCACTGGTACCTGGCATGGGCCGGATACAACACCGGCTCCGGGCGCGTCCGGCGGATGGTGGAGCGG
CACGGGACGACGAACTTCTGGCTCCTGTCCGAAGAGCGCGGCCTGGCGAAGGAGACGAAGCACTACGTGCCCAAGCTGAT
TGCCGCGGCGCTGGTGGCCAAGCACCCGGCGGCGTTCGGCTTCAACGAGAACGAGTTCGACCCCGAGCCCGTGCTCGACT
TCGATGAGGTGCAGCTCACCGACGCGGCGGACCTGGACGTCGTCGCCCGCGCGGCCGGCGTGCCCGTCAAGGTGGTGCAG
GACCTCAACCCTGAGCTGAAGCGCTGGTGCACCCCGCCGGCGACGGCCAAGAAGCCCTACACGCTCCGGCTTCCCAAGGG
GGCAGGGACGCAGTTCGCGGACAACTACAAGCGCATCAGCCCCGCGGAGCGGCTCACCTTCCGCATCCACAAGGTGAAGC
GCGGCGACACCCTGTCCCAGATCGCGGAGACGTACGGCACGGCGTCCGAGGCCATCCTCCAAATGAACCAGCTGAAGTCG
GCCCGGACGTTGCGCGTGGGTGGAGAGCTGGTGATTCCGATTCCCGCCGGCAAGAGCTCGGGCGGCGCGCTGGCGACGAA
GGTGGCGCAGGCCCGCCGCAGCGGCGTGGTGGTGCGGCCCGAGGACGAGGTACCAGCGGGCACGCCCAAAGGCCCGGTGG
CCGCGGGCCCCGTGAAGAAGGAGACCATCAACGGGCGCACGCGCGTGACGTACGGCGTGATGTCCGGCGACAGCCTCTGG
GTGATTGCGAACAAGTTCAACGTGTCGGTGGACTCGCTGAAGCAGTGGAACAACCTCAAGCGGCGCAACCCGACGCTCCA
GGTGGGCTCCACGCTGTTCGTCTGGCCCGATGGCAACACGGCCACCGCCAGCGTGCAGGAGCGCGGCGGCACGGTGCTGG
CGAAGCACTCGGTGAGCGTCGCCAAGCCCGCGGGCAAGGCTGGCAAGGTCCACGCGCTGGCGGAGGGCGAGACGCTCTGG
TCCGTCGCGCAGCGCTACGGCGTCAGCGTGGACGACATCATGCGGTGGAACAAGATCAAGGACCACCGCACCCTCCCCAC
GGGGAAGGTGCTCCTCCTCAGCGCCCCGTAG

Upstream 100 bases:

>100_bases
AAACAAGACGCGCAGGCCGCGACTCCTTGTTTGACTGTCAAGGAAAAGGGCGATTACTTCCCGCTTTCGCCCGCCTCCGG
GCGCCCGTTCCCGCGACTGT

Downstream 100 bases:

>100_bases
TCTCCGGCGCGTACACGGTGAAGGCGAGCTCCGCACCCACACTGGCGAGCTGCTGGACGACGAGTTCCGGCACGGGGAAG
GCGCTCGAATGGGGCTCCAG

Product: Slt family transglycosylase

Products: 1,6-Anhydrobond In The Muramic Acid Residue [C]

Alternate protein names: Murein hydrolase D; Regulatory protein dniR [H]

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MPPLPLLLLALASAPASGLTPPPVGPVPAKAQVVESEGAQAPAAQSPAEKEPTAATEPGAADTGTDAVDEPGLEPLEPGT
PMVAEDASEQGEATRDAVESESAELEELRALEGAALDPASRSTAEVMQSLRRLGVANPLRMRMLDALDEHTFREDEELPE
IPLITDLATFDVGQIQDRYDIPVEMQPLVAQYVQFFQGPGRRWFRKWMSRAARYVPVMHPILEQYGLPKDTVYLAMIESG
FSAHAYSWAHAAGPWQFISSTGKQYGLKQDFWVDERRDPIKATHAAASYLKDLKRELGHWYLAWAGYNTGSGRVRRMVER
HGTTNFWLLSEERGLAKETKHYVPKLIAAALVAKHPAAFGFNENEFDPEPVLDFDEVQLTDAADLDVVARAAGVPVKVVQ
DLNPELKRWCTPPATAKKPYTLRLPKGAGTQFADNYKRISPAERLTFRIHKVKRGDTLSQIAETYGTASEAILQMNQLKS
ARTLRVGGELVIPIPAGKSSGGALATKVAQARRSGVVVRPEDEVPAGTPKGPVAAGPVKKETINGRTRVTYGVMSGDSLW
VIANKFNVSVDSLKQWNNLKRRNPTLQVGSTLFVWPDGNTATASVQERGGTVLAKHSVSVAKPAGKAGKVHALAEGETLW
SVAQRYGVSVDDIMRWNKIKDHRTLPTGKVLLLSAP

Sequences:

>Translated_676_residues
MPPLPLLLLALASAPASGLTPPPVGPVPAKAQVVESEGAQAPAAQSPAEKEPTAATEPGAADTGTDAVDEPGLEPLEPGT
PMVAEDASEQGEATRDAVESESAELEELRALEGAALDPASRSTAEVMQSLRRLGVANPLRMRMLDALDEHTFREDEELPE
IPLITDLATFDVGQIQDRYDIPVEMQPLVAQYVQFFQGPGRRWFRKWMSRAARYVPVMHPILEQYGLPKDTVYLAMIESG
FSAHAYSWAHAAGPWQFISSTGKQYGLKQDFWVDERRDPIKATHAAASYLKDLKRELGHWYLAWAGYNTGSGRVRRMVER
HGTTNFWLLSEERGLAKETKHYVPKLIAAALVAKHPAAFGFNENEFDPEPVLDFDEVQLTDAADLDVVARAAGVPVKVVQ
DLNPELKRWCTPPATAKKPYTLRLPKGAGTQFADNYKRISPAERLTFRIHKVKRGDTLSQIAETYGTASEAILQMNQLKS
ARTLRVGGELVIPIPAGKSSGGALATKVAQARRSGVVVRPEDEVPAGTPKGPVAAGPVKKETINGRTRVTYGVMSGDSLW
VIANKFNVSVDSLKQWNNLKRRNPTLQVGSTLFVWPDGNTATASVQERGGTVLAKHSVSVAKPAGKAGKVHALAEGETLW
SVAQRYGVSVDDIMRWNKIKDHRTLPTGKVLLLSAP
>Mature_675_residues
PPLPLLLLALASAPASGLTPPPVGPVPAKAQVVESEGAQAPAAQSPAEKEPTAATEPGAADTGTDAVDEPGLEPLEPGTP
MVAEDASEQGEATRDAVESESAELEELRALEGAALDPASRSTAEVMQSLRRLGVANPLRMRMLDALDEHTFREDEELPEI
PLITDLATFDVGQIQDRYDIPVEMQPLVAQYVQFFQGPGRRWFRKWMSRAARYVPVMHPILEQYGLPKDTVYLAMIESGF
SAHAYSWAHAAGPWQFISSTGKQYGLKQDFWVDERRDPIKATHAAASYLKDLKRELGHWYLAWAGYNTGSGRVRRMVERH
GTTNFWLLSEERGLAKETKHYVPKLIAAALVAKHPAAFGFNENEFDPEPVLDFDEVQLTDAADLDVVARAAGVPVKVVQD
LNPELKRWCTPPATAKKPYTLRLPKGAGTQFADNYKRISPAERLTFRIHKVKRGDTLSQIAETYGTASEAILQMNQLKSA
RTLRVGGELVIPIPAGKSSGGALATKVAQARRSGVVVRPEDEVPAGTPKGPVAAGPVKKETINGRTRVTYGVMSGDSLWV
IANKFNVSVDSLKQWNNLKRRNPTLQVGSTLFVWPDGNTATASVQERGGTVLAKHSVSVAKPAGKAGKVHALAEGETLWS
VAQRYGVSVDDIMRWNKIKDHRTLPTGKVLLLSAP

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786405, Length=402, Percent_Identity=29.3532338308458, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR010511
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01476 LysM; PF06474 MLTD_N; PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 73573; Mature: 73442

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPLPLLLLALASAPASGLTPPPVGPVPAKAQVVESEGAQAPAAQSPAEKEPTAATEPGA
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCC
ADTGTDAVDEPGLEPLEPGTPMVAEDASEQGEATRDAVESESAELEELRALEGAALDPAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RSTAEVMQSLRRLGVANPLRMRMLDALDEHTFREDEELPEIPLITDLATFDVGQIQDRYD
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCHHHCCCCCC
IPVEMQPLVAQYVQFFQGPGRRWFRKWMSRAARYVPVMHPILEQYGLPKDTVYLAMIESG
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCC
FSAHAYSWAHAAGPWQFISSTGKQYGLKQDFWVDERRDPIKATHAAASYLKDLKRELGHW
CCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
YLAWAGYNTGSGRVRRMVERHGTTNFWLLSEERGLAKETKHYVPKLIAAALVAKHPAAFG
EEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
FNENEFDPEPVLDFDEVQLTDAADLDVVARAAGVPVKVVQDLNPELKRWCTPPATAKKPY
CCCCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCCHHHHHCCCHHHHHHCCCCCCCCCCE
TLRLPKGAGTQFADNYKRISPAERLTFRIHKVKRGDTLSQIAETYGTASEAILQMNQLKS
EEECCCCCCCCHHHHHHHCCHHHHHHHHEEHHCCCCHHHHHHHHHCCHHHHHHHHHHHHC
ARTLRVGGELVIPIPAGKSSGGALATKVAQARRSGVVVRPEDEVPAGTPKGPVAAGPVKK
CCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCH
ETINGRTRVTYGVMSGDSLWVIANKFNVSVDSLKQWNNLKRRNPTLQVGSTLFVWPDGNT
HHCCCCEEEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCEEEEECCCCC
ATASVQERGGTVLAKHSVSVAKPAGKAGKVHALAEGETLWSVAQRYGVSVDDIMRWNKIK
EEEEHHHCCCEEEEECCCHHCCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHCC
DHRTLPTGKVLLLSAP
CCCCCCCCCEEEEECC
>Mature Secondary Structure 
PPLPLLLLALASAPASGLTPPPVGPVPAKAQVVESEGAQAPAAQSPAEKEPTAATEPGA
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCC
ADTGTDAVDEPGLEPLEPGTPMVAEDASEQGEATRDAVESESAELEELRALEGAALDPAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RSTAEVMQSLRRLGVANPLRMRMLDALDEHTFREDEELPEIPLITDLATFDVGQIQDRYD
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCHHHCCCCCC
IPVEMQPLVAQYVQFFQGPGRRWFRKWMSRAARYVPVMHPILEQYGLPKDTVYLAMIESG
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCC
FSAHAYSWAHAAGPWQFISSTGKQYGLKQDFWVDERRDPIKATHAAASYLKDLKRELGHW
CCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
YLAWAGYNTGSGRVRRMVERHGTTNFWLLSEERGLAKETKHYVPKLIAAALVAKHPAAFG
EEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
FNENEFDPEPVLDFDEVQLTDAADLDVVARAAGVPVKVVQDLNPELKRWCTPPATAKKPY
CCCCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCCHHHHHCCCHHHHHHCCCCCCCCCCE
TLRLPKGAGTQFADNYKRISPAERLTFRIHKVKRGDTLSQIAETYGTASEAILQMNQLKS
EEECCCCCCCCHHHHHHHCCHHHHHHHHEEHHCCCCHHHHHHHHHCCHHHHHHHHHHHHC
ARTLRVGGELVIPIPAGKSSGGALATKVAQARRSGVVVRPEDEVPAGTPKGPVAAGPVKK
CCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCH
ETINGRTRVTYGVMSGDSLWVIANKFNVSVDSLKQWNNLKRRNPTLQVGSTLFVWPDGNT
HHCCCCEEEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCEEEEECCCCC
ATASVQERGGTVLAKHSVSVAKPAGKAGKVHALAEGETLWSVAQRYGVSVDDIMRWNKIK
EEEEHHHCCCEEEEECCCHHCCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHCC
DHRTLPTGKVLLLSAP
CCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]