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The map label for this gene is pqqL [C]

Identifier: 108758171

GI number: 108758171

Start: 4427422

End: 4428735

Strand: Direct

Name: pqqL [C]

Synonym: MXAN_3712

Alternate gene names: 108758171

Gene position: 4427422-4428735 (Clockwise)

Preceding gene: 108760620

Following gene: 108763119

Centisome position: 48.44

GC content: 66.89

Gene sequence:

>1314_bases
ATGTCCAAGGCTTCCCCGAGCAAAGTACCCACTCGCGTGGCGGACCCCGCACTCGAGTCCCTGTTCGACGTCCACGAGGC
CACGCTTCCCAACGGCCTCCAGGTGCGGTTGCTCGCCAACCACCAGGCTCCTGTCGTCAGTCTCTACACCGTGTTCCAGG
TCGGCAGCCGCAACGAGCGGCCCGGCATCACCGGCATCAGCCACCTGTTCGAGCACATGATGTTCAACGGGGCGAAGAAG
TACGGCCCCAAGATGTTCGACAAGACGCTGGAGTCCAACGGCGGCCGCTCGAACGCGTACACGTCCACGGACTTGACGGT
GTACTACGACGACTTCTCCGCCGACGCGCTGGAGACGGTGCTGGACCTGGAGTCGGACCGGATGCGCTCGCTGCGCATCT
CCCAGCAGACGCTCACCAGCGAGCGCGAGGTGGTGAAGGAAGAGCGCCGCGTCCGCGTGGACAACGACATCTTCGGCCTC
ATGGACGAGGAGCTGGGCACGCTCGTCTACAAGGCGCATCCCTACCGCTGGCCTGTCATTGGATGGATGGCGGACATCGA
GGCCATCCGCCGCGAGGACTGCCAGGACTACTTCCGCACCTACTACGCGCCCAACAACGCGGTGCTCTACATCGTCGGGG
CCATCGACCCGAAGAAGACGCTGGCGCTGGTGCGCAAGTACTACGGGAGCATCCCCAAGGGCCCCGCGCCCGCGGCGGTG
CTCAACTCCGAGCCCGAGCAGAAGGGCGAGCGCCGCGCCGAGGTCCGCCACCCCGCGCAGTCCCCCGCGCTGATGCTGGG
CTTCCGGGGGCCGGCCTCGCGCGATGACGACACCTTCGTGCTGGACGTCATCCAGTACGTGCTGACGAAGGGGGAGGGGA
GCCGGCTGATCCGCTCGCTGGTGTACGAGCAGAAGCTGGCCGTGTCGCTGATGCTCGACTGGAGCTGGCGCATCGACCCG
GGCACCATCCTCTTCTACCTGGCCCTGAAGCCGGACTCCGACCCGAAGAAGGTGGAGGCCGCGCTGTACGCCGAACTGGA
GAAGATCGCGCGAGAGGGCATCACCGAGCGCGAGCTGCAGAAGGCGCAGAACAACCTGCGCTCGGACCACCTGCGCGAGC
TGGCCACGAACAGCGGCCGGGCGCATGCCCTGGGCCACTACGAGGCGCTGCTCGGTGACTGGCGCCGGTTGCTGACGCTG
CCCTCCACCTACACCTCCATTACCAACGACCAGGTCAAGGCCGTGGCCGCGAAGTACTTCGCGCCCGAGCACCGCTCCGT
GGTGACGCTGGTTCCCGCGCCCACCGAAGCCTGA

Upstream 100 bases:

>100_bases
CCGGAAGATGGGCGTCAACTCTCACGTGGAGGCCGTGGTGATGGCCCTGCGTGCGGGTGTCGTGGATCTATAGCCACGCT
CTGGTTAGGTTCGGGGTCCT

Downstream 100 bases:

>100_bases
GCCCGGTCCGTACAAGGAAACCTTCCGATATGGCTTCTCGCAAGAGCCCCTCCCGAAAGTCCCCCGCACGTCCGGCGAAG
CGCGCCGGCGGCAAGGCCCC

Product: M16 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSKASPSKVPTRVADPALESLFDVHEATLPNGLQVRLLANHQAPVVSLYTVFQVGSRNERPGITGISHLFEHMMFNGAKK
YGPKMFDKTLESNGGRSNAYTSTDLTVYYDDFSADALETVLDLESDRMRSLRISQQTLTSEREVVKEERRVRVDNDIFGL
MDEELGTLVYKAHPYRWPVIGWMADIEAIRREDCQDYFRTYYAPNNAVLYIVGAIDPKKTLALVRKYYGSIPKGPAPAAV
LNSEPEQKGERRAEVRHPAQSPALMLGFRGPASRDDDTFVLDVIQYVLTKGEGSRLIRSLVYEQKLAVSLMLDWSWRIDP
GTILFYLALKPDSDPKKVEAALYAELEKIAREGITERELQKAQNNLRSDHLRELATNSGRAHALGHYEALLGDWRRLLTL
PSTYTSITNDQVKAVAAKYFAPEHRSVVTLVPAPTEA

Sequences:

>Translated_437_residues
MSKASPSKVPTRVADPALESLFDVHEATLPNGLQVRLLANHQAPVVSLYTVFQVGSRNERPGITGISHLFEHMMFNGAKK
YGPKMFDKTLESNGGRSNAYTSTDLTVYYDDFSADALETVLDLESDRMRSLRISQQTLTSEREVVKEERRVRVDNDIFGL
MDEELGTLVYKAHPYRWPVIGWMADIEAIRREDCQDYFRTYYAPNNAVLYIVGAIDPKKTLALVRKYYGSIPKGPAPAAV
LNSEPEQKGERRAEVRHPAQSPALMLGFRGPASRDDDTFVLDVIQYVLTKGEGSRLIRSLVYEQKLAVSLMLDWSWRIDP
GTILFYLALKPDSDPKKVEAALYAELEKIAREGITERELQKAQNNLRSDHLRELATNSGRAHALGHYEALLGDWRRLLTL
PSTYTSITNDQVKAVAAKYFAPEHRSVVTLVPAPTEA
>Mature_436_residues
SKASPSKVPTRVADPALESLFDVHEATLPNGLQVRLLANHQAPVVSLYTVFQVGSRNERPGITGISHLFEHMMFNGAKKY
GPKMFDKTLESNGGRSNAYTSTDLTVYYDDFSADALETVLDLESDRMRSLRISQQTLTSEREVVKEERRVRVDNDIFGLM
DEELGTLVYKAHPYRWPVIGWMADIEAIRREDCQDYFRTYYAPNNAVLYIVGAIDPKKTLALVRKYYGSIPKGPAPAAVL
NSEPEQKGERRAEVRHPAQSPALMLGFRGPASRDDDTFVLDVIQYVLTKGEGSRLIRSLVYEQKLAVSLMLDWSWRIDPG
TILFYLALKPDSDPKKVEAALYAELEKIAREGITERELQKAQNNLRSDHLRELATNSGRAHALGHYEALLGDWRRLLTLP
STYTSITNDQVKAVAAKYFAPEHRSVVTLVPAPTEA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=300, Percent_Identity=25, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI94538354, Length=187, Percent_Identity=27.807486631016, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI155969707, Length=229, Percent_Identity=27.9475982532751, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI24308013, Length=212, Percent_Identity=27.3584905660377, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787770, Length=365, Percent_Identity=27.1232876712329, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71999683, Length=425, Percent_Identity=23.2941176470588, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17553678, Length=370, Percent_Identity=21.8918918918919, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=211, Percent_Identity=28.9099526066351, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321813, Length=381, Percent_Identity=23.6220472440945, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357875, Length=417, Percent_Identity=23.2613908872902, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646943, Length=417, Percent_Identity=23.2613908872902, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49160; Mature: 49029

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKASPSKVPTRVADPALESLFDVHEATLPNGLQVRLLANHQAPVVSLYTVFQVGSRNER
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCC
PGITGISHLFEHMMFNGAKKYGPKMFDKTLESNGGRSNAYTSTDLTVYYDDFSADALETV
CCCHHHHHHHHHHHHCCHHHHCHHHHHHHHHCCCCCCCCEECCCEEEEECCCCHHHHHHH
LDLESDRMRSLRISQQTLTSEREVVKEERRVRVDNDIFGLMDEELGTLVYKAHPYRWPVI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHEEEECCCCCCCHH
GWMADIEAIRREDCQDYFRTYYAPNNAVLYIVGAIDPKKTLALVRKYYGSIPKGPAPAAV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHH
LNSEPEQKGERRAEVRHPAQSPALMLGFRGPASRDDDTFVLDVIQYVLTKGEGSRLIRSL
HCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
VYEQKLAVSLMLDWSWRIDPGTILFYLALKPDSDPKKVEAALYAELEKIAREGITERELQ
HHHHHHEEEEEEECCEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
KAQNNLRSDHLRELATNSGRAHALGHYEALLGDWRRLLTLPSTYTSITNDQVKAVAAKYF
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHC
APEHRSVVTLVPAPTEA
CCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SKASPSKVPTRVADPALESLFDVHEATLPNGLQVRLLANHQAPVVSLYTVFQVGSRNER
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCC
PGITGISHLFEHMMFNGAKKYGPKMFDKTLESNGGRSNAYTSTDLTVYYDDFSADALETV
CCCHHHHHHHHHHHHCCHHHHCHHHHHHHHHCCCCCCCCEECCCEEEEECCCCHHHHHHH
LDLESDRMRSLRISQQTLTSEREVVKEERRVRVDNDIFGLMDEELGTLVYKAHPYRWPVI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHEEEECCCCCCCHH
GWMADIEAIRREDCQDYFRTYYAPNNAVLYIVGAIDPKKTLALVRKYYGSIPKGPAPAAV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHH
LNSEPEQKGERRAEVRHPAQSPALMLGFRGPASRDDDTFVLDVIQYVLTKGEGSRLIRSL
HCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
VYEQKLAVSLMLDWSWRIDPGTILFYLALKPDSDPKKVEAALYAELEKIAREGITERELQ
HHHHHHEEEEEEECCEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
KAQNNLRSDHLRELATNSGRAHALGHYEALLGDWRRLLTLPSTYTSITNDQVKAVAAKYF
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHC
APEHRSVVTLVPAPTEA
CCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]