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The map label for this gene is degU [H]

Identifier: 108760620

GI number: 108760620

Start: 4426723

End: 4427394

Strand: Direct

Name: degU [H]

Synonym: MXAN_3711

Alternate gene names: 108760620

Gene position: 4426723-4427394 (Clockwise)

Preceding gene: 108760459

Following gene: 108758171

Centisome position: 48.43

GC content: 65.33

Gene sequence:

>672_bases
GTGACCATGGACCCGACCCGCATCTTCGTCGTCGAGGATCAACCCCAGCTCCTCAAGAACCTGGTGAAGGTGCTGGCCAC
CTTCCCCGAACTGGAGGTGGTAGGCACCTCCCAGGAAGGGGAGGCCGCGGTGGAGGACATCGTCCAGCTCCGCCCCCAGC
TCGTCCTCCTGGACCTGGAGTTGCCCGGCATCAACGGCATCCAGGTGACCCAGCGGGTGAAGCGCCGCGCCCCGGAGGTG
GAGATCCTCATCCTCACGTCCTTCGATGACGAGACGAAGGTCTACGAGGCCATCCAGGCCGGGGCCTCCGGCTACCTGGT
GAAGCGGGTGGGGCCGGAGAAGATCCGCTCCGGCATCCAGGAGGTGATGGAGGGCGGGACAGTCTTGGAGCCCATCATCG
CCAAGCGCTTCTGGAACTACTTCCAGTCCGTTCAGGCGAAGTCCACCCAGGCGGAGAAGAAGCTGGAGAACCCCTGGGCG
CTCACGCCGCTGGAGTTCGAGGTGCTGCGCTACGTGGCCAAGGGCCTGTCCAACGCCGAGGTGGGGCACGTGATGACGCT
GGAGCGGCGGACGGTGCGCACGCACCTGTCGCATATCTACCGGAAGATGGGCGTCAACTCTCACGTGGAGGCCGTGGTGA
TGGCCCTGCGTGCGGGTGTCGTGGATCTATAG

Upstream 100 bases:

>100_bases
TGGTGTCCGTCGCCACCGGTGAGCCCAAGGAGCTGGACCTGCGCATCACGCGGGGGCAGCACCTCAAGGTCCTGGTGGAC
TCGTTCACGTCTCCGAGGCG

Downstream 100 bases:

>100_bases
CCACGCTCTGGTTAGGTTCGGGGTCCTATGTCCAAGGCTTCCCCGAGCAAAGTACCCACTCGCGTGGCGGACCCCGCACT
CGAGTCCCTGTTCGACGTCC

Product: LuxR family DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTMDPTRIFVVEDQPQLLKNLVKVLATFPELEVVGTSQEGEAAVEDIVQLRPQLVLLDLELPGINGIQVTQRVKRRAPEV
EILILTSFDDETKVYEAIQAGASGYLVKRVGPEKIRSGIQEVMEGGTVLEPIIAKRFWNYFQSVQAKSTQAEKKLENPWA
LTPLEFEVLRYVAKGLSNAEVGHVMTLERRTVRTHLSHIYRKMGVNSHVEAVVMALRAGVVDL

Sequences:

>Translated_223_residues
MTMDPTRIFVVEDQPQLLKNLVKVLATFPELEVVGTSQEGEAAVEDIVQLRPQLVLLDLELPGINGIQVTQRVKRRAPEV
EILILTSFDDETKVYEAIQAGASGYLVKRVGPEKIRSGIQEVMEGGTVLEPIIAKRFWNYFQSVQAKSTQAEKKLENPWA
LTPLEFEVLRYVAKGLSNAEVGHVMTLERRTVRTHLSHIYRKMGVNSHVEAVVMALRAGVVDL
>Mature_222_residues
TMDPTRIFVVEDQPQLLKNLVKVLATFPELEVVGTSQEGEAAVEDIVQLRPQLVLLDLELPGINGIQVTQRVKRRAPEVE
ILILTSFDDETKVYEAIQAGASGYLVKRVGPEKIRSGIQEVMEGGTVLEPIIAKRFWNYFQSVQAKSTQAEKKLENPWAL
TPLEFEVLRYVAKGLSNAEVGHVMTLERRTVRTHLSHIYRKMGVNSHVEAVVMALRAGVVDL

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=214, Percent_Identity=29.4392523364486, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786747, Length=217, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788222, Length=216, Percent_Identity=26.8518518518519, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=27.4038461538462, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787473, Length=214, Percent_Identity=29.4392523364486, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=24.6305418719212, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24972; Mature: 24841

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMDPTRIFVVEDQPQLLKNLVKVLATFPELEVVGTSQEGEAAVEDIVQLRPQLVLLDLE
CCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEEE
LPGINGIQVTQRVKRRAPEVEILILTSFDDETKVYEAIQAGASGYLVKRVGPEKIRSGIQ
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
EVMEGGTVLEPIIAKRFWNYFQSVQAKSTQAEKKLENPWALTPLEFEVLRYVAKGLSNAE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCC
VGHVMTLERRTVRTHLSHIYRKMGVNSHVEAVVMALRAGVVDL
CCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TMDPTRIFVVEDQPQLLKNLVKVLATFPELEVVGTSQEGEAAVEDIVQLRPQLVLLDLE
CCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEEE
LPGINGIQVTQRVKRRAPEVEILILTSFDDETKVYEAIQAGASGYLVKRVGPEKIRSGIQ
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
EVMEGGTVLEPIIAKRFWNYFQSVQAKSTQAEKKLENPWALTPLEFEVLRYVAKGLSNAE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCC
VGHVMTLERRTVRTHLSHIYRKMGVNSHVEAVVMALRAGVVDL
CCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]