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The map label for this gene is rtcR [H]

Identifier: 108758086

GI number: 108758086

Start: 6231048

End: 6232670

Strand: Direct

Name: rtcR [H]

Synonym: MXAN_4983

Alternate gene names: 108758086

Gene position: 6231048-6232670 (Clockwise)

Preceding gene: 108763469

Following gene: 108760639

Centisome position: 68.18

GC content: 70.18

Gene sequence:

>1623_bases
ATGGCGAAATCGCGCGCGCGCAAGACGGTGGTCCTGGGGATGCTCGGGACGACGCTGGACAACGGGCAGGGGCCGCAGCG
CTGGGCGCGGTGGCGGCCCACGGTGGCGCTGTGCCAGCAGGAGGACCTGTTGGTGCACCGGCTGGAGTTGTTGCATCCAC
CGAACGCGACCTCGCTCGCGGCCACACTGGCGGGGGACATCCGCCAGGTGTCACCGGAGACGGAGGTGCGGGGCAGGCCC
CTGCGCATCCAGAACCCGTGGGACCTGGAGGAGACCTACGGCGCGCTGCTCGACTACGTGCGCGGCTATGCCTTCAACCC
CGAGGCGGAGGACTACCTGGTCCACATCACCACGGGCACGCACATCGCGCAGATCTGCATGTTCCTGCTGGTGGAGAGCC
GGCTCATCCCCGGCAAGCTGGTCCAGGTGTCACCCGACCCCCGGGACCGCGCGGGCGCGGGTACGCACACCCTCATCGAC
CTGGACTTGTCCCAGTACGACACCCTGGCCGCGCGCTTCCGGCAGGAGCAGCGAGAAGGCCTGGCCTTCCTCAAGTCCGG
CATCGACACCCGCAACGCGGCGTTCAACCGCCTCATCGAGCGCATCGAACAGGTGGCCGTCCAGTCCCGCGCGCCCCTGC
TCATCACGGGCCCCACCGGCGCGGGCAAGTCGCAGCTCGCGCGGCGCATCTACGCGCTGAAGAAGTCGCGGCGCGGCGTG
GCGGGCCCCTTCGTGGACCTCAACTGCGCCACGCTCCGGGGCGACGGCGCCATGTCCGCGCTCTTCGGCCACGTGAAGGG
CGCCTTCACGGGCGCGCTGAGCGACAGGCCCGGTCTGCTGCGGCAGGCGAATGGCGGCGTGCTGTTCCTGGACGAAATCG
GCGAGCTGGGCGCGGACGAGCAGGCCATGTTGCTCCGCGCGCTGGAGGACAAGCGCTTCTTGCCCGTGGGCGCGGACCGA
GAGGTGGAGAGCGACTTCCAGCTCATCGCCGGCACCAACCGGGACCTCCAAGTCGAGGTCGAGCGCGGGCGCTTCCGGGA
GGACCTGCTCGCGCGCATCAACCTGTGGACGTTCCGGCTGCCCGCGCTGCGCGAGCGCCCGGAGGACATTCCACCCAACC
TGCTCTTCGAACTGGACCAGTCCTCCGAGGCCGTGGGCACGCGCGTCACCATGAACAAGGAGGCGCAGGAGCGCTTTCTG
GACTTCGCCACGTCCACCGAGGCGAGGTGGGCAGGCAACTTCCGGGACCTCAACGCGGCGGTGCTGCGCATGGCCACGCT
GGCGGCGGGCGGACGGATTACTCGGGACGTGGTGGACGAGGAGCTCGAACGGCTGCGCGAGCAGTGGCGGCCCTCCGGAG
CGAAGGCGGCGGTCGTCGCCGGGGACCTGGTCGCGGAGGTGCTGGGAGAGAACCTCGCCAGCGAGCTGGACCGTTTCGAC
CGGGTCCAACTCGCGGACGTGCTGAGCGTCTGCCGGGCATCACGCTCGTTGTCGGACGCGGGGCGCTTGCTGTTCGCTCA
GTCACGCGCCCAGAAGAAGAGCGTCAACGACGCGGACCGGCTGAAGAAGTACCTGGCCCGCTTCGGACTCACGTGGGCGG
ACGCCAGCGGGCGAGGCGCGTAG

Upstream 100 bases:

>100_bases
CGGAGGAGGCCTAGAGCAGCCGGCGTGCCAACACCGCTTCCGAGGGGAGCCCTCCAAGCGAGCTGGCATTCCCTATCCCC
ATAGATAAAATCCTATCTCG

Downstream 100 bases:

>100_bases
GCCGGGCTCAGAGCATGGGCATGCCACGCGTCGTCACGCCCTTGCCTCCCTTTGCGCCCTGACTTCGCTGCCCGCCCTGC
CCATCGCGGCCCAGGAGGTA

Product: sigma-54 dependent transcriptional regulator RtcR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MAKSRARKTVVLGMLGTTLDNGQGPQRWARWRPTVALCQQEDLLVHRLELLHPPNATSLAATLAGDIRQVSPETEVRGRP
LRIQNPWDLEETYGALLDYVRGYAFNPEAEDYLVHITTGTHIAQICMFLLVESRLIPGKLVQVSPDPRDRAGAGTHTLID
LDLSQYDTLAARFRQEQREGLAFLKSGIDTRNAAFNRLIERIEQVAVQSRAPLLITGPTGAGKSQLARRIYALKKSRRGV
AGPFVDLNCATLRGDGAMSALFGHVKGAFTGALSDRPGLLRQANGGVLFLDEIGELGADEQAMLLRALEDKRFLPVGADR
EVESDFQLIAGTNRDLQVEVERGRFREDLLARINLWTFRLPALRERPEDIPPNLLFELDQSSEAVGTRVTMNKEAQERFL
DFATSTEARWAGNFRDLNAAVLRMATLAAGGRITRDVVDEELERLREQWRPSGAKAAVVAGDLVAEVLGENLASELDRFD
RVQLADVLSVCRASRSLSDAGRLLFAQSRAQKKSVNDADRLKKYLARFGLTWADASGRGA

Sequences:

>Translated_540_residues
MAKSRARKTVVLGMLGTTLDNGQGPQRWARWRPTVALCQQEDLLVHRLELLHPPNATSLAATLAGDIRQVSPETEVRGRP
LRIQNPWDLEETYGALLDYVRGYAFNPEAEDYLVHITTGTHIAQICMFLLVESRLIPGKLVQVSPDPRDRAGAGTHTLID
LDLSQYDTLAARFRQEQREGLAFLKSGIDTRNAAFNRLIERIEQVAVQSRAPLLITGPTGAGKSQLARRIYALKKSRRGV
AGPFVDLNCATLRGDGAMSALFGHVKGAFTGALSDRPGLLRQANGGVLFLDEIGELGADEQAMLLRALEDKRFLPVGADR
EVESDFQLIAGTNRDLQVEVERGRFREDLLARINLWTFRLPALRERPEDIPPNLLFELDQSSEAVGTRVTMNKEAQERFL
DFATSTEARWAGNFRDLNAAVLRMATLAAGGRITRDVVDEELERLREQWRPSGAKAAVVAGDLVAEVLGENLASELDRFD
RVQLADVLSVCRASRSLSDAGRLLFAQSRAQKKSVNDADRLKKYLARFGLTWADASGRGA
>Mature_539_residues
AKSRARKTVVLGMLGTTLDNGQGPQRWARWRPTVALCQQEDLLVHRLELLHPPNATSLAATLAGDIRQVSPETEVRGRPL
RIQNPWDLEETYGALLDYVRGYAFNPEAEDYLVHITTGTHIAQICMFLLVESRLIPGKLVQVSPDPRDRAGAGTHTLIDL
DLSQYDTLAARFRQEQREGLAFLKSGIDTRNAAFNRLIERIEQVAVQSRAPLLITGPTGAGKSQLARRIYALKKSRRGVA
GPFVDLNCATLRGDGAMSALFGHVKGAFTGALSDRPGLLRQANGGVLFLDEIGELGADEQAMLLRALEDKRFLPVGADRE
VESDFQLIAGTNRDLQVEVERGRFREDLLARINLWTFRLPALRERPEDIPPNLLFELDQSSEAVGTRVTMNKEAQERFLD
FATSTEARWAGNFRDLNAAVLRMATLAAGGRITRDVVDEELERLREQWRPSGAKAAVVAGDLVAEVLGENLASELDRFDR
VQLADVLSVCRASRSLSDAGRLLFAQSRAQKKSVNDADRLKKYLARFGLTWADASGRGA

Specific function: Transcriptional repressor of the rtcAB genes. Interacts with sigma-54 [H]

COG id: COG4650

COG function: function code KT; Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789828, Length=530, Percent_Identity=60.188679245283, Blast_Score=634, Evalue=0.0,
Organism=Escherichia coli, GI1788905, Length=260, Percent_Identity=38.0769230769231, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1788550, Length=362, Percent_Identity=33.7016574585635, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1790437, Length=250, Percent_Identity=40.4, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI87082152, Length=247, Percent_Identity=40.8906882591093, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790299, Length=237, Percent_Identity=38.3966244725738, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1789233, Length=240, Percent_Identity=36.25, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87082117, Length=254, Percent_Identity=35.8267716535433, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789087, Length=286, Percent_Identity=35.3146853146853, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787583, Length=242, Percent_Identity=39.6694214876033, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081872, Length=232, Percent_Identity=36.2068965517241, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1786524, Length=260, Percent_Identity=35, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI87081858, Length=237, Percent_Identity=30.379746835443, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR002078
- InterPro:   IPR009715
- InterPro:   IPR017183 [H]

Pfam domain/function: PF06956 RtcR; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 59727; Mature: 59596

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSRARKTVVLGMLGTTLDNGQGPQRWARWRPTVALCQQEDLLVHRLELLHPPNATSLA
CCCCHHHHEEEEEHHHCCCCCCCCHHHHHHCCCHHHHHCHHHHHHHHHHHCCCCCHHHHH
ATLAGDIRQVSPETEVRGRPLRIQNPWDLEETYGALLDYVRGYAFNPEAEDYLVHITTGT
HHHHHHHHHCCCCHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCH
HIAQICMFLLVESRLIPGKLVQVSPDPRDRAGAGTHTLIDLDLSQYDTLAARFRQEQREG
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
LAFLKSGIDTRNAAFNRLIERIEQVAVQSRAPLLITGPTGAGKSQLARRIYALKKSRRGV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCC
AGPFVDLNCATLRGDGAMSALFGHVKGAFTGALSDRPGLLRQANGGVLFLDEIGELGADE
CCCEEECEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEEEECHHCCCCCH
QAMLLRALEDKRFLPVGADREVESDFQLIAGTNRDLQVEVERGRFREDLLARINLWTFRL
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEHHCCHHHHHHHHHHHHEEEC
PALRERPEDIPPNLLFELDQSSEAVGTRVTMNKEAQERFLDFATSTEARWAGNFRDLNAA
CHHHCCCCCCCCHHEEEECCCCCCCCEEEEECHHHHHHHHHHHCCCCHHHCCCCHHHHHH
VLRMATLAAGGRITRDVVDEELERLREQWRPSGAKAAVVAGDLVAEVLGENLASELDRFD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
RVQLADVLSVCRASRSLSDAGRLLFAQSRAQKKSVNDADRLKKYLARFGLTWADASGRGA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCCC
>Mature Secondary Structure 
AKSRARKTVVLGMLGTTLDNGQGPQRWARWRPTVALCQQEDLLVHRLELLHPPNATSLA
CCCHHHHEEEEEHHHCCCCCCCCHHHHHHCCCHHHHHCHHHHHHHHHHHCCCCCHHHHH
ATLAGDIRQVSPETEVRGRPLRIQNPWDLEETYGALLDYVRGYAFNPEAEDYLVHITTGT
HHHHHHHHHCCCCHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCH
HIAQICMFLLVESRLIPGKLVQVSPDPRDRAGAGTHTLIDLDLSQYDTLAARFRQEQREG
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
LAFLKSGIDTRNAAFNRLIERIEQVAVQSRAPLLITGPTGAGKSQLARRIYALKKSRRGV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCC
AGPFVDLNCATLRGDGAMSALFGHVKGAFTGALSDRPGLLRQANGGVLFLDEIGELGADE
CCCEEECEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEEEECHHCCCCCH
QAMLLRALEDKRFLPVGADREVESDFQLIAGTNRDLQVEVERGRFREDLLARINLWTFRL
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEHHCCHHHHHHHHHHHHEEEC
PALRERPEDIPPNLLFELDQSSEAVGTRVTMNKEAQERFLDFATSTEARWAGNFRDLNAA
CHHHCCCCCCCCHHEEEECCCCCCCCEEEEECHHHHHHHHHHHCCCCHHHCCCCHHHHHH
VLRMATLAAGGRITRDVVDEELERLREQWRPSGAKAAVVAGDLVAEVLGENLASELDRFD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
RVQLADVLSVCRASRSLSDAGRLLFAQSRAQKKSVNDADRLKKYLARFGLTWADASGRGA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3045764; 7984428; 7920643; 9738023 [H]