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The map label for this gene is selD

Identifier: 108758025

GI number: 108758025

Start: 2334752

End: 2335810

Strand: Direct

Name: selD

Synonym: MXAN_2002

Alternate gene names: 108758025

Gene position: 2334752-2335810 (Clockwise)

Preceding gene: 108761898

Following gene: 108758052

Centisome position: 25.54

GC content: 69.78

Gene sequence:

>1059_bases
ATGGCGGAGAAGAAGACGGACAAGGTGAAGCGCCTCACCGAGCTGAGCCACTGCGCGGGCTGCGCGGCGAAGCTGCGGGC
CTCGGACCTGGCGCAGGTGCTGGGGGGGCTGAAGTCCACGAAGGGCCCCCAGGCGCTGGTGGGGTTCTCCACGAATGACG
ACGCGGCCGTGTACCGGCTGGCGCCCGGCATGGCCGTGGTGGAGACGGTGGACTTCTTTCCCCCGGTGGTGGACGACCCG
TTCCAGTTCGGGGCCATTGCCGCGGCGAACGCGCTGTCGGACATCTACGCCATGGGCGCGCGGCCCCTCTTCGCGCTCAA
CCTGGTGTGCTTCCCGGATGAGCTCCCGCTGAAGGTGCTGTCGAAAATCCTGGCGGGCGGCCAGTCCAAGGCGGACGAGG
CCGGCATCCCCATCCTGGGCGGCCACAGCATCCGTGACCCCGAGCCGAAGTTCGGCATGGCCGTCACCGGCGTGGTGCAC
CCGAAGAAGGTGCTCACCAACGCGGGCGCGAAGCCGGGGGACGTGCTCTTTCTCACCAAGCCCCTGGGCTCGGGCATCGC
GACCACCGCCATCAAGCGGGGCGTGGCGTCCAAGCAGTTGGCGAAGCGGGCCCTGGGGGTGATGACGACGCTCAACCGGG
CCGCCGGCGAGGTGTTCGCCTCCGGGAAGTTCAAGGTGAACGCCCTCACGGACGTGACGGGCTACGGCTTGTTGGGGCAC
TTGCTGGAGATGATGACCGCGGCGAAGGCGCGCGCCACGCTGGACCTGGAGCGCATCCCGCTCATCGCCGAGGTCCCCGC
GCTGGCGGAGGACGGCGTGGTGCCCGGCGGTACGAAGTCGAACCTCGCCCACGTCCACAAGAAGGTCCGCTTCCCCGAAG
GACTGCCCGAGTGCATCCAGTGGGTGCTCGCGGATGCGCAGACCAACGGCGGCCTCCTGGCCAGCGTCCCCGCACGTCAG
GCGCTCAAGGCGCTCAAGGCGCTGGAGGCGGCCGGCGTGGACGCGGCGCTGATTGGTGAAGTCCAGGCGGGGAAGCCGGG
CATCGACGTGGTGGGCTGA

Upstream 100 bases:

>100_bases
GCAACTGCTCAAGCGGGACTACATCCGAGCGGCCTGAGCGGTGAACGGGCCGGGCCCTTTCCGGGGCCCGTGCCGGGACG
GCGAGGCGTGGGGAGCGGGC

Downstream 100 bases:

>100_bases
GGCCCGGATTTCGCTCTGGCGGCCGGGCTCCGCTAGCATGCGGCCCCAGCATGCCGTCGCCGCGCCGCCCCCTCCTCGGC
CTCCTGGCCCTGCTCTGGCT

Product: selenide, water dikinase

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAEKKTDKVKRLTELSHCAGCAAKLRASDLAQVLGGLKSTKGPQALVGFSTNDDAAVYRLAPGMAVVETVDFFPPVVDDP
FQFGAIAAANALSDIYAMGARPLFALNLVCFPDELPLKVLSKILAGGQSKADEAGIPILGGHSIRDPEPKFGMAVTGVVH
PKKVLTNAGAKPGDVLFLTKPLGSGIATTAIKRGVASKQLAKRALGVMTTLNRAAGEVFASGKFKVNALTDVTGYGLLGH
LLEMMTAAKARATLDLERIPLIAEVPALAEDGVVPGGTKSNLAHVHKKVRFPEGLPECIQWVLADAQTNGGLLASVPARQ
ALKALKALEAAGVDAALIGEVQAGKPGIDVVG

Sequences:

>Translated_352_residues
MAEKKTDKVKRLTELSHCAGCAAKLRASDLAQVLGGLKSTKGPQALVGFSTNDDAAVYRLAPGMAVVETVDFFPPVVDDP
FQFGAIAAANALSDIYAMGARPLFALNLVCFPDELPLKVLSKILAGGQSKADEAGIPILGGHSIRDPEPKFGMAVTGVVH
PKKVLTNAGAKPGDVLFLTKPLGSGIATTAIKRGVASKQLAKRALGVMTTLNRAAGEVFASGKFKVNALTDVTGYGLLGH
LLEMMTAAKARATLDLERIPLIAEVPALAEDGVVPGGTKSNLAHVHKKVRFPEGLPECIQWVLADAQTNGGLLASVPARQ
ALKALKALEAAGVDAALIGEVQAGKPGIDVVG
>Mature_351_residues
AEKKTDKVKRLTELSHCAGCAAKLRASDLAQVLGGLKSTKGPQALVGFSTNDDAAVYRLAPGMAVVETVDFFPPVVDDPF
QFGAIAAANALSDIYAMGARPLFALNLVCFPDELPLKVLSKILAGGQSKADEAGIPILGGHSIRDPEPKFGMAVTGVVHP
KKVLTNAGAKPGDVLFLTKPLGSGIATTAIKRGVASKQLAKRALGVMTTLNRAAGEVFASGKFKVNALTDVTGYGLLGHL
LEMMTAAKARATLDLERIPLIAEVPALAEDGVVPGGTKSNLAHVHKKVRFPEGLPECIQWVLADAQTNGGLLASVPARQA
LKALKALEAAGVDAALIGEVQAGKPGIDVVG

Specific function: Synthesizes selenophosphate from selenide and ATP

COG id: COG0709

COG function: function code E; Selenophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily

Homologues:

Organism=Homo sapiens, GI24797148, Length=374, Percent_Identity=27.807486631016, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI15011844, Length=307, Percent_Identity=29.3159609120521, Blast_Score=118, Evalue=8e-27,
Organism=Escherichia coli, GI1788062, Length=343, Percent_Identity=42.5655976676385, Blast_Score=231, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17543426, Length=355, Percent_Identity=29.8591549295775, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24653602, Length=304, Percent_Identity=32.5657894736842, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24653604, Length=304, Percent_Identity=32.5657894736842, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574119, Length=349, Percent_Identity=26.647564469914, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28574118, Length=258, Percent_Identity=29.0697674418605, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SELD_MYXXD (Q1DAT6)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_630237.1
- ProteinModelPortal:   Q1DAT6
- SMR:   Q1DAT6
- STRING:   Q1DAT6
- GeneID:   4105182
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_2002
- TIGR:   MXAN_2002
- eggNOG:   COG0709
- HOGENOM:   HBG383791
- OMA:   HKLARAS
- PhylomeDB:   Q1DAT6
- BioCyc:   MXAN246197:MXAN_2002-MONOMER
- HAMAP:   MF_00625
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061
- PIRSF:   PIRSF036407
- TIGRFAMs:   TIGR00476

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =2.7.9.3

Molecular weight: Translated: 36360; Mature: 36229

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: ACT_SITE 21-21

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKTDKVKRLTELSHCAGCAAKLRASDLAQVLGGLKSTKGPQALVGFSTNDDAAVYRL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEE
APGMAVVETVDFFPPVVDDPFQFGAIAAANALSDIYAMGARPLFALNLVCFPDELPLKVL
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHH
SKILAGGQSKADEAGIPILGGHSIRDPEPKFGMAVTGVVHPKKVLTNAGAKPGDVLFLTK
HHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHCCCCCCCCEEEEEC
PLGSGIATTAIKRGVASKQLAKRALGVMTTLNRAAGEVFASGKFKVNALTDVTGYGLLGH
CCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
LLEMMTAAKARATLDLERIPLIAEVPALAEDGVVPGGTKSNLAHVHKKVRFPEGLPECIQ
HHHHHHHHHHHHHCCHHHCCHHHHCCCHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
WVLADAQTNGGLLASVPARQALKALKALEAAGVDAALIGEVQAGKPGIDVVG
HHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCC
>Mature Secondary Structure 
AEKKTDKVKRLTELSHCAGCAAKLRASDLAQVLGGLKSTKGPQALVGFSTNDDAAVYRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEE
APGMAVVETVDFFPPVVDDPFQFGAIAAANALSDIYAMGARPLFALNLVCFPDELPLKVL
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHH
SKILAGGQSKADEAGIPILGGHSIRDPEPKFGMAVTGVVHPKKVLTNAGAKPGDVLFLTK
HHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHCCCCCCCCEEEEEC
PLGSGIATTAIKRGVASKQLAKRALGVMTTLNRAAGEVFASGKFKVNALTDVTGYGLLGH
CCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
LLEMMTAAKARATLDLERIPLIAEVPALAEDGVVPGGTKSNLAHVHKKVRFPEGLPECIQ
HHHHHHHHHHHHHCCHHHCCHHHHCCCHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
WVLADAQTNGGLLASVPARQALKALKALEAAGVDAALIGEVQAGKPGIDVVG
HHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA