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The map label for this gene is amiC [H]

Identifier: 108758052

GI number: 108758052

Start: 2335861

End: 2336670

Strand: Direct

Name: amiC [H]

Synonym: MXAN_2003

Alternate gene names: 108758052

Gene position: 2335861-2336670 (Clockwise)

Preceding gene: 108758025

Following gene: 108758625

Centisome position: 25.56

GC content: 72.84

Gene sequence:

>810_bases
ATGCCGTCGCCGCGCCGCCCCCTCCTCGGCCTCCTGGCCCTGCTCTGGCTGGTCCCCGTCATCGCCGGGGCGGCGGAGCG
TCCCGCGCGCATCATCATCGACCCGGGACACGGTGGTGCGAAGGAAGGCGCCAAGGGCCCCGGCAAGCTGCGGGAGAAGG
ACGTCGCGCTCCAGATTTCGCTCCGCCTCCGGGACAAGCTCGAGGCCGCGGGGGGCGACGTGTTCCTGACGCGCGAGCAC
GACACGCTGGTGTCGTTGACGGAGCGCGTGGCGTGGAGCAATGACCACGCGCCCGACCTCTTCATCTCCATCCACGCCAA
CTCCATGCCCACGAAGCGGATGCGCGCGCGCACCGAGGGCGTGGAGACGTACTTTCTGTCCGCCAGCGCCTCGGGTGACG
CCGCGCTCGCCGTGGCGGATCGGGAGAACGCGGAGGCGCCCATGTCGCGCGCCACGCGGACGGACTCCACGCTGGCCTTC
ATCCTCCAGGACCTGGCGCGCACGGAGGCGCACGCGGATTCCTCGCGCCTGGCCTACGCCATCCACCCGCGCCTCGTGCG
CGGCACCCGCGCGGTGAACCGGGGCGTGCAGCAGGCGCCCTTCTTCGTCCTCTCCGGCGTGGAGTGCCCGGCCGTCCTCG
TGGAGGTGGGCTACATCTCCCATCCCGTGGAGGGGCCCCGGCTGGGCCGGCCGGAGTACCAGGAGAAGCTGGCCGAGGCG
ATTACCGAGGGCGTGCTGGCCTTCCTCAAGGAGACGCGCCGCCGGGACGCCGCCCGGGGGACCGAGGTGGCTGGCCCCGT
GTCGCCCTGA

Upstream 100 bases:

>100_bases
TGATTGGTGAAGTCCAGGCGGGGAAGCCGGGCATCGACGTGGTGGGCTGAGGCCCGGATTTCGCTCTGGCGGCCGGGCTC
CGCTAGCATGCGGCCCCAGC

Downstream 100 bases:

>100_bases
GTGCAACGGCGCCAAGGCAATCGACACCCGCGCGGCGTGGCTCTGGTAGAGAAGGGGACGCTCGTCCTCATTTCCCAGGA
GCCTGCTGTGCGTTCCTTTC

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MPSPRRPLLGLLALLWLVPVIAGAAERPARIIIDPGHGGAKEGAKGPGKLREKDVALQISLRLRDKLEAAGGDVFLTREH
DTLVSLTERVAWSNDHAPDLFISIHANSMPTKRMRARTEGVETYFLSASASGDAALAVADRENAEAPMSRATRTDSTLAF
ILQDLARTEAHADSSRLAYAIHPRLVRGTRAVNRGVQQAPFFVLSGVECPAVLVEVGYISHPVEGPRLGRPEYQEKLAEA
ITEGVLAFLKETRRRDAARGTEVAGPVSP

Sequences:

>Translated_269_residues
MPSPRRPLLGLLALLWLVPVIAGAAERPARIIIDPGHGGAKEGAKGPGKLREKDVALQISLRLRDKLEAAGGDVFLTREH
DTLVSLTERVAWSNDHAPDLFISIHANSMPTKRMRARTEGVETYFLSASASGDAALAVADRENAEAPMSRATRTDSTLAF
ILQDLARTEAHADSSRLAYAIHPRLVRGTRAVNRGVQQAPFFVLSGVECPAVLVEVGYISHPVEGPRLGRPEYQEKLAEA
ITEGVLAFLKETRRRDAARGTEVAGPVSP
>Mature_268_residues
PSPRRPLLGLLALLWLVPVIAGAAERPARIIIDPGHGGAKEGAKGPGKLREKDVALQISLRLRDKLEAAGGDVFLTREHD
TLVSLTERVAWSNDHAPDLFISIHANSMPTKRMRARTEGVETYFLSASASGDAALAVADRENAEAPMSRATRTDSTLAFI
LQDLARTEAHADSSRLAYAIHPRLVRGTRAVNRGVQQAPFFVLSGVECPAVLVEVGYISHPVEGPRLGRPEYQEKLAEAI
TEGVLAFLKETRRRDAARGTEVAGPVSP

Specific function: Cell-wall hydrolase involved in septum cleavage during cell division [H]

COG id: COG0860

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

Organism=Escherichia coli, GI87082163, Length=229, Percent_Identity=33.6244541484716, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788776, Length=222, Percent_Identity=35.1351351351351, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790611, Length=229, Percent_Identity=29.6943231441048, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021731
- InterPro:   IPR002508
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01520 Amidase_3; PF11741 AMIN [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 29045; Mature: 28913

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPRRPLLGLLALLWLVPVIAGAAERPARIIIDPGHGGAKEGAKGPGKLREKDVALQIS
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEE
LRLRDKLEAAGGDVFLTREHDTLVSLTERVAWSNDHAPDLFISIHANSMPTKRMRARTEG
EHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCC
VETYFLSASASGDAALAVADRENAEAPMSRATRTDSTLAFILQDLARTEAHADSSRLAYA
CEEEEEEECCCCCEEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEE
IHPRLVRGTRAVNRGVQQAPFFVLSGVECPAVLVEVGYISHPVEGPRLGRPEYQEKLAEA
ECHHHHHHHHHHHCCHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ITEGVLAFLKETRRRDAARGTEVAGPVSP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PSPRRPLLGLLALLWLVPVIAGAAERPARIIIDPGHGGAKEGAKGPGKLREKDVALQIS
CCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEE
LRLRDKLEAAGGDVFLTREHDTLVSLTERVAWSNDHAPDLFISIHANSMPTKRMRARTEG
EHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCC
VETYFLSASASGDAALAVADRENAEAPMSRATRTDSTLAFILQDLARTEAHADSSRLAYA
CEEEEEEECCCCCEEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEE
IHPRLVRGTRAVNRGVQQAPFFVLSGVECPAVLVEVGYISHPVEGPRLGRPEYQEKLAEA
ECHHHHHHHHHHHCCHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ITEGVLAFLKETRRRDAARGTEVAGPVSP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]