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The map label for this gene is dgk [H]

Identifier: 108757889

GI number: 108757889

Start: 2386086

End: 2386730

Strand: Direct

Name: dgk [H]

Synonym: MXAN_2054

Alternate gene names: 108757889

Gene position: 2386086-2386730 (Clockwise)

Preceding gene: 108758752

Following gene: 108756848

Centisome position: 26.11

GC content: 62.79

Gene sequence:

>645_bases
ATGGACTACCGGTATATCGTGGTGGAAGGGCCCATTGGCGTGGGCAAGACGAGCCTCTCCAATATCCTCGCGGAGCGTCT
GGCGGGACGGCGCATCCTCGAAGTGGTGGAGGAGAACCCCTTCCTGTCCAGCTTCTACACGGACCGGCAGAAGTTCGCGT
TCCAGACGCAGATCTTCTTCCTGCTGTCGCGCTTCCGTCAGCAGCAGGAGCTGTTCCAGCAGGACCTCTTCAGCTCGATG
ACGGTCAGCGACTACCTGTTCGCCAAGGACCGCATCTTCGCGCACCTCAACCTGGACGCGCACGAGCTGGCCCTCTACGA
GCGCGTCTTCGAGGCGCTGGGGCCCCGCGTGGCCAAGCCGGACCTGGTCATCTACCTCCAGGCCCGACTGGACGTGCTCC
TGCACCGCATCAAGAAGCGCGGCCGGGAGTTCGAGCGCAAGTTCGACCCCACGTACCTGGAGGGGCTCGTCCACTCCTAC
AACAACTTCTTCTTCCACTACACGGACACCCCGCTCCTCGTCGTGGATACCTCCGACATCGACTTCGTGAATGTCGAGGC
AGACAGGGAAGACCTGCTTGCCACCATCCGGAAGGCGAAGCCGGGCACGCAGCATTACGTTCCGAAGGCTTCCCGCCGGG
GCTGA

Upstream 100 bases:

>100_bases
CCGTGTTGTGTTATCCGCCCGCGTGCGTGGCCGCGCCTTCGCGCGATGTCTCGCGCGCGCGGTCTCAAAGCGCATTCCGC
GGGCGGGAGGCCTCGGGCGG

Downstream 100 bases:

>100_bases
AAGTCAGGCTCCTGGTGGGACGTCCGCCTTCAACCTCCCCACGGCCGGCGCGGTGGCGTTAGAGTGCGGTGGCGGGCCCA
GGGCTCCCGGCGATCCCCGG

Product: deoxynucleoside kinase family protein

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MDYRYIVVEGPIGVGKTSLSNILAERLAGRRILEVVEENPFLSSFYTDRQKFAFQTQIFFLLSRFRQQQELFQQDLFSSM
TVSDYLFAKDRIFAHLNLDAHELALYERVFEALGPRVAKPDLVIYLQARLDVLLHRIKKRGREFERKFDPTYLEGLVHSY
NNFFFHYTDTPLLVVDTSDIDFVNVEADREDLLATIRKAKPGTQHYVPKASRRG

Sequences:

>Translated_214_residues
MDYRYIVVEGPIGVGKTSLSNILAERLAGRRILEVVEENPFLSSFYTDRQKFAFQTQIFFLLSRFRQQQELFQQDLFSSM
TVSDYLFAKDRIFAHLNLDAHELALYERVFEALGPRVAKPDLVIYLQARLDVLLHRIKKRGREFERKFDPTYLEGLVHSY
NNFFFHYTDTPLLVVDTSDIDFVNVEADREDLLATIRKAKPGTQHYVPKASRRG
>Mature_214_residues
MDYRYIVVEGPIGVGKTSLSNILAERLAGRRILEVVEENPFLSSFYTDRQKFAFQTQIFFLLSRFRQQQELFQQDLFSSM
TVSDYLFAKDRIFAHLNLDAHELALYERVFEALGPRVAKPDLVIYLQARLDVLLHRIKKRGREFERKFDPTYLEGLVHSY
NNFFFHYTDTPLLVVDTSDIDFVNVEADREDLLATIRKAKPGTQHYVPKASRRG

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 25048; Mature: 25048

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRYIVVEGPIGVGKTSLSNILAERLAGRRILEVVEENPFLSSFYTDRQKFAFQTQIFF
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LLSRFRQQQELFQQDLFSSMTVSDYLFAKDRIFAHLNLDAHELALYERVFEALGPRVAKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCCCC
DLVIYLQARLDVLLHRIKKRGREFERKFDPTYLEGLVHSYNNFFFHYTDTPLLVVDTSDI
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCEEEEEECCCC
DFVNVEADREDLLATIRKAKPGTQHYVPKASRRG
CEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDYRYIVVEGPIGVGKTSLSNILAERLAGRRILEVVEENPFLSSFYTDRQKFAFQTQIFF
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LLSRFRQQQELFQQDLFSSMTVSDYLFAKDRIFAHLNLDAHELALYERVFEALGPRVAKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCCCC
DLVIYLQARLDVLLHRIKKRGREFERKFDPTYLEGLVHSYNNFFFHYTDTPLLVVDTSDI
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCEEEEEECCCC
DFVNVEADREDLLATIRKAKPGTQHYVPKASRRG
CEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]