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The map label for this gene is yheS [H]

Identifier: 108757726

GI number: 108757726

Start: 3882602

End: 3884575

Strand: Direct

Name: yheS [H]

Synonym: MXAN_3339

Alternate gene names: 108757726

Gene position: 3882602-3884575 (Clockwise)

Preceding gene: 108759295

Following gene: 108761379

Centisome position: 42.48

GC content: 68.24

Gene sequence:

>1974_bases
ATGAGCCTCGTCATCGCCCAGGACCTCTGTCTCTCCTACGGAAAGAAGGTCCTCTTCGATCAGGACAGTTTCACACTGGG
TCCCAGGGACCGGGTGGGCCTCGTAGGGGCCAACGGGACGGGTAAGAGCTCGCTGATGAAAATCCTGGCGGGCGTGTCCC
AGGCCGACTCGGGGACGGTGCAATACAGCCGCAAGGCCCGAGCGGGCTACCTGCCGCAGGAAATCGCCGGGTTGCCGGAT
GGCACCGTGGTGGAGGCGGTGATGAGCACCGTGCCCGGCCGCGATGCCATGGAGGCGCGCCTCAAGGAGACGGAGGCTGC
GCTCGCCGCCGCCACGGACGAGGAGGACCAGCTGGAGCTGTCCCAGTCCCTGGCGGACCTGCATGCGGAGCTGGACGACT
TCGAGAACCGCTACGGCCGCCACCACGCCGAGCGCATCCTCAAGGGTCTGGGCTTCCGCGACACGGACCTGGCCAAGCCC
ACCTCCGCGCTGTCCGGCGGCTGGCGGATGCGCGCGGCCCTGGCGGGACTGCTGCTCCAGGACCCCGACCTGCTCCTGTT
GGACGAGCCCACCAACCACCTGGACGTGCCCACGCTCACGTGGTTCGACGACTTCATGCGCCGCTCCAACAAGGCGCTGG
TGCTCATCTCCCACGACAAGGACTTCCTCAACCGGCAGATCAACCGGGTGGTGTCCCTGGAAGTGGAGGGCGTGCGCGAG
TACGCGGGGAACTACGACGAATACAAGCGCCTGCGCGCGGAGGAGAAGGAGCTGTTGAGGGCCCGCGCCGAGAAGGTGGA
GTCGCGCCGCGCGGAGCTGCAGGGCTTCATCGACCGCTTCGGCGCCAAGGCCACCAAGGCGCGTCAGGCCCAGAGCCGCG
CCAAGATGTTGGAGAAGCTGGAGAAGGTGCAGGTCCTGGAGGAGCGGACGTCGATGAAGTTCCGCTTCCCCGAGGTCGAG
CGGAGCGGGCGCGACGTGGTGACGCTGGAGGGCATCACCAAACGGTACGGCGCGCAGACCATCTACGACGGCCTCACCGG
GCGCGTGGAGCGTGGGCAGCGCATCGCCGTGGTGGGCGCGAACGGCGCGGGCAAGACGACACTCCTGAAGATGGTCGCTG
GCGAGCTGGCGCCGGACACCGGGACGGTGACGCTGGGGCACAACGTGGTGGTGGGCTATTACGCGCAGCACCACGCGGAC
AAGCTGAACCGGCAGAACACCATCATCGAAGAGGTGCGCCCGCTGGCCGCGGACAAGCCGGAGAGCTACGTGCGCGGCGT
GCTGGGCGCGTTCCTCTTCAGCGGCGATGAGGTGGAGAAGCCCATTGGCGTGCTGAGTGGTGGTGAGCGCGCGCGGGTGG
CGCTGGCCAAGCTGTTGCTGGTGCCGTCCAACTTCCTGCTGATGGACGAGCCCACCAACCACCTGGACCTGGACTCGGCC
GAGATGCTGATTGAAGCGCTGAAGGGCTACGGCGGCACGTTGCTGTTCGTCAGCCACAGCCGGAGCTTCATCAACGGCCT
GGCGTCGCACGTGTGGGAGGTCGCGGATGGGAAGCTCACGCCGCATCCGGGCAACCTGGACGACTACCTGTACCACCAGC
AGAAGCTCCAGCAGGCGGCGGCGGAGGCCTCGGCCCTGGCGGCGGGCCAGGCGCGGGGTGAGAAGGTGGCCTCCGGGCCG
ATGACGGAGAAGGACCGCAAGCGGCTGGAGGCGGAGGCGCGCCAGCGCCGCAGCGTGGTGGAGGGGCCCCTCAAGAAGGA
AATTGCGAAGCTGGAGGCGCGCATCGCCGAGGTGGAGGCCGGACAGAAGGAGCGCGAGGCGCAGCTCGCGGACCCGGCCC
TCTACAACGACTTCGCGCGCGCCAAGCCGCTGATGGACACGCACCGCGCGAGCAAGGAGGAGCTGGAAGACCTCTATGCC
CGCTGGGAGGCTGCGCAGGAGAAGCTGGCCGAGGCGTCCGCGTCACTGGGATGA

Upstream 100 bases:

>100_bases
CCCCGGCCCAACCCGGAAAGCCCCTGTAGGGCCCCAGAGCGAACGGGCGGGCACATCCGACATTCCCGAGGGGCTCGCGG
GCTGTTACATCCCCGGCGCC

Downstream 100 bases:

>100_bases
GGGCCGCGCGGCGCTCGCCCGGCTCATCGGGTGAGCATCCGGTGGAGCAGCCACATCAAGCCCTCGGAGGCGTACCCGGC
CAGGTTGAAGGTCTGGCCTC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 656

Protein sequence:

>657_residues
MSLVIAQDLCLSYGKKVLFDQDSFTLGPRDRVGLVGANGTGKSSLMKILAGVSQADSGTVQYSRKARAGYLPQEIAGLPD
GTVVEAVMSTVPGRDAMEARLKETEAALAAATDEEDQLELSQSLADLHAELDDFENRYGRHHAERILKGLGFRDTDLAKP
TSALSGGWRMRAALAGLLLQDPDLLLLDEPTNHLDVPTLTWFDDFMRRSNKALVLISHDKDFLNRQINRVVSLEVEGVRE
YAGNYDEYKRLRAEEKELLRARAEKVESRRAELQGFIDRFGAKATKARQAQSRAKMLEKLEKVQVLEERTSMKFRFPEVE
RSGRDVVTLEGITKRYGAQTIYDGLTGRVERGQRIAVVGANGAGKTTLLKMVAGELAPDTGTVTLGHNVVVGYYAQHHAD
KLNRQNTIIEEVRPLAADKPESYVRGVLGAFLFSGDEVEKPIGVLSGGERARVALAKLLLVPSNFLLMDEPTNHLDLDSA
EMLIEALKGYGGTLLFVSHSRSFINGLASHVWEVADGKLTPHPGNLDDYLYHQQKLQQAAAEASALAAGQARGEKVASGP
MTEKDRKRLEAEARQRRSVVEGPLKKEIAKLEARIAEVEAGQKEREAQLADPALYNDFARAKPLMDTHRASKEELEDLYA
RWEAAQEKLAEASASLG

Sequences:

>Translated_657_residues
MSLVIAQDLCLSYGKKVLFDQDSFTLGPRDRVGLVGANGTGKSSLMKILAGVSQADSGTVQYSRKARAGYLPQEIAGLPD
GTVVEAVMSTVPGRDAMEARLKETEAALAAATDEEDQLELSQSLADLHAELDDFENRYGRHHAERILKGLGFRDTDLAKP
TSALSGGWRMRAALAGLLLQDPDLLLLDEPTNHLDVPTLTWFDDFMRRSNKALVLISHDKDFLNRQINRVVSLEVEGVRE
YAGNYDEYKRLRAEEKELLRARAEKVESRRAELQGFIDRFGAKATKARQAQSRAKMLEKLEKVQVLEERTSMKFRFPEVE
RSGRDVVTLEGITKRYGAQTIYDGLTGRVERGQRIAVVGANGAGKTTLLKMVAGELAPDTGTVTLGHNVVVGYYAQHHAD
KLNRQNTIIEEVRPLAADKPESYVRGVLGAFLFSGDEVEKPIGVLSGGERARVALAKLLLVPSNFLLMDEPTNHLDLDSA
EMLIEALKGYGGTLLFVSHSRSFINGLASHVWEVADGKLTPHPGNLDDYLYHQQKLQQAAAEASALAAGQARGEKVASGP
MTEKDRKRLEAEARQRRSVVEGPLKKEIAKLEARIAEVEAGQKEREAQLADPALYNDFARAKPLMDTHRASKEELEDLYA
RWEAAQEKLAEASASLG
>Mature_656_residues
SLVIAQDLCLSYGKKVLFDQDSFTLGPRDRVGLVGANGTGKSSLMKILAGVSQADSGTVQYSRKARAGYLPQEIAGLPDG
TVVEAVMSTVPGRDAMEARLKETEAALAAATDEEDQLELSQSLADLHAELDDFENRYGRHHAERILKGLGFRDTDLAKPT
SALSGGWRMRAALAGLLLQDPDLLLLDEPTNHLDVPTLTWFDDFMRRSNKALVLISHDKDFLNRQINRVVSLEVEGVREY
AGNYDEYKRLRAEEKELLRARAEKVESRRAELQGFIDRFGAKATKARQAQSRAKMLEKLEKVQVLEERTSMKFRFPEVER
SGRDVVTLEGITKRYGAQTIYDGLTGRVERGQRIAVVGANGAGKTTLLKMVAGELAPDTGTVTLGHNVVVGYYAQHHADK
LNRQNTIIEEVRPLAADKPESYVRGVLGAFLFSGDEVEKPIGVLSGGERARVALAKLLLVPSNFLLMDEPTNHLDLDSAE
MLIEALKGYGGTLLFVSHSRSFINGLASHVWEVADGKLTPHPGNLDDYLYHQQKLQQAAAEASALAAGQARGEKVASGPM
TEKDRKRLEAEARQRRSVVEGPLKKEIAKLEARIAEVEAGQKEREAQLADPALYNDFARAKPLMDTHRASKEELEDLYAR
WEAAQEKLAEASASLG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=530, Percent_Identity=33.3962264150943, Blast_Score=299, Evalue=5e-81,
Organism=Homo sapiens, GI10947137, Length=534, Percent_Identity=32.7715355805243, Blast_Score=251, Evalue=2e-66,
Organism=Homo sapiens, GI27881506, Length=534, Percent_Identity=33.1460674157303, Blast_Score=250, Evalue=3e-66,
Organism=Homo sapiens, GI69354671, Length=543, Percent_Identity=29.6500920810313, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI10947135, Length=543, Percent_Identity=29.6500920810313, Blast_Score=215, Evalue=1e-55,
Organism=Escherichia coli, GI1789751, Length=654, Percent_Identity=36.2385321100917, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI1787041, Length=531, Percent_Identity=36.9114877589454, Blast_Score=354, Evalue=1e-98,
Organism=Escherichia coli, GI1787182, Length=654, Percent_Identity=30.5810397553517, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI2367384, Length=535, Percent_Identity=32.7102803738318, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1788165, Length=185, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788225, Length=223, Percent_Identity=26.457399103139, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787164, Length=206, Percent_Identity=28.1553398058252, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786803, Length=217, Percent_Identity=30.4147465437788, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48995001, Length=185, Percent_Identity=28.1081081081081, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI87081782, Length=200, Percent_Identity=29, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=533, Percent_Identity=33.2082551594747, Blast_Score=281, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17555318, Length=530, Percent_Identity=30.9433962264151, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17559834, Length=543, Percent_Identity=30.5709023941068, Blast_Score=244, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6321121, Length=539, Percent_Identity=32.0964749536178, Blast_Score=272, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6320874, Length=548, Percent_Identity=33.7591240875912, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6323278, Length=392, Percent_Identity=28.5714285714286, Blast_Score=147, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6324314, Length=407, Percent_Identity=27.5184275184275, Blast_Score=147, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6325030, Length=409, Percent_Identity=26.4058679706601, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=35.673624288425, Blast_Score=336, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24642252, Length=528, Percent_Identity=33.9015151515151, Blast_Score=271, Evalue=9e-73,
Organism=Drosophila melanogaster, GI18859989, Length=528, Percent_Identity=33.9015151515151, Blast_Score=271, Evalue=9e-73,
Organism=Drosophila melanogaster, GI24641342, Length=519, Percent_Identity=30.635838150289, Blast_Score=246, Evalue=5e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72336; Mature: 72205

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVIAQDLCLSYGKKVLFDQDSFTLGPRDRVGLVGANGTGKSSLMKILAGVSQADSGTV
CCEEHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCE
QYSRKARAGYLPQEIAGLPDGTVVEAVMSTVPGRDAMEARLKETEAALAAATDEEDQLEL
EECHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
SQSLADLHAELDDFENRYGRHHAERILKGLGFRDTDLAKPTSALSGGWRMRAALAGLLLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHC
DPDLLLLDEPTNHLDVPTLTWFDDFMRRSNKALVLISHDKDFLNRQINRVVSLEVEGVRE
CCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHEEEHHHHHH
YAGNYDEYKRLRAEEKELLRARAEKVESRRAELQGFIDRFGAKATKARQAQSRAKMLEKL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EKVQVLEERTSMKFRFPEVERSGRDVVTLEGITKRYGAQTIYDGLTGRVERGQRIAVVGA
HHHHHHHHHHCCEEECCHHHCCCCCEEEECCHHHHHCCHHHHHHHCCHHCCCCEEEEEEC
NGAGKTTLLKMVAGELAPDTGTVTLGHNVVVGYYAQHHADKLNRQNTIIEEVRPLAADKP
CCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ESYVRGVLGAFLFSGDEVEKPIGVLSGGERARVALAKLLLVPSNFLLMDEPTNHLDLDSA
HHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHH
EMLIEALKGYGGTLLFVSHSRSFINGLASHVWEVADGKLTPHPGNLDDYLYHQQKLQQAA
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
AEASALAAGQARGEKVASGPMTEKDRKRLEAEARQRRSVVEGPLKKEIAKLEARIAEVEA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
GQKEREAQLADPALYNDFARAKPLMDTHRASKEELEDLYARWEAAQEKLAEASASLG
CCHHHHHHHCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLVIAQDLCLSYGKKVLFDQDSFTLGPRDRVGLVGANGTGKSSLMKILAGVSQADSGTV
CEEHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCE
QYSRKARAGYLPQEIAGLPDGTVVEAVMSTVPGRDAMEARLKETEAALAAATDEEDQLEL
EECHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
SQSLADLHAELDDFENRYGRHHAERILKGLGFRDTDLAKPTSALSGGWRMRAALAGLLLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHC
DPDLLLLDEPTNHLDVPTLTWFDDFMRRSNKALVLISHDKDFLNRQINRVVSLEVEGVRE
CCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHEEEHHHHHH
YAGNYDEYKRLRAEEKELLRARAEKVESRRAELQGFIDRFGAKATKARQAQSRAKMLEKL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EKVQVLEERTSMKFRFPEVERSGRDVVTLEGITKRYGAQTIYDGLTGRVERGQRIAVVGA
HHHHHHHHHHCCEEECCHHHCCCCCEEEECCHHHHHCCHHHHHHHCCHHCCCCEEEEEEC
NGAGKTTLLKMVAGELAPDTGTVTLGHNVVVGYYAQHHADKLNRQNTIIEEVRPLAADKP
CCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ESYVRGVLGAFLFSGDEVEKPIGVLSGGERARVALAKLLLVPSNFLLMDEPTNHLDLDSA
HHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHH
EMLIEALKGYGGTLLFVSHSRSFINGLASHVWEVADGKLTPHPGNLDDYLYHQQKLQQAA
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
AEASALAAGQARGEKVASGPMTEKDRKRLEAEARQRRSVVEGPLKKEIAKLEARIAEVEA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
GQKEREAQLADPALYNDFARAKPLMDTHRASKEELEDLYARWEAAQEKLAEASASLG
CCHHHHHHHCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]