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The map label for this gene is rho [H]

Identifier: 108757528

GI number: 108757528

Start: 2885918

End: 2887618

Strand: Reverse

Name: rho [H]

Synonym: MXAN_2479

Alternate gene names: 108757528

Gene position: 2887618-2885918 (Counterclockwise)

Preceding gene: 108758821

Following gene: 108757783

Centisome position: 31.59

GC content: 70.55

Gene sequence:

>1701_bases
TTGGGCCGCCAGGGTGCTCCAGGAAACGGCGGTTCGGCCTGCTCGTCACCAGGGCCCCGCGTCCGCTTCCTGTCCCACGG
CCTGAGTCACCTTGCGTCCCCGCCCTCCTCGTGGAGCGGCCGCCCGGGGCGCACACAGTCTGGAACGTTCATGAGCGAAA
ACCCCGATAACCGCGACCCACGTGATGCCCCCCCCGTTCCCGCCGCCCGCGCCGTGGCGCCGCCCGAGCCGGACGATGAC
GGTGGCGACGAGGGCGACGACGAGGGGCCCGACGACGGTGATTCCGGCGGGGGCGCACAGGGTGGCGCCCCCGGGCAGCC
TGGCCAGGCCACCGGCCGCCGCCGCCGCCGTCGGCGCCGTCGCCGTGGCGCGCAGGTCCTCTTCACCCCGGACGGCCAGG
CCTACCGGATGCAGCCTGGAGCGGACGGCCAGCAGGTCCAGGTGTTCCTCACGCCGCAGGAGCTGGAGCAGTACCGCCAG
CGACAGGCGCAGCAACAACAGCAACAGCAGCAACCACCGCAGCCGGCGCACGGCGGCGGGGGCCAGCAGCACGCCCGCCA
CGCGCAGCACGGGGGCGGCGGCCAGCAGGCCTCGCAGCAGGCGAACCTGTCGCCGGTGGAGGGCGTGCTGGACACGGAGG
CCAAGGGCCCCAACGCCTTCCTGCGCCAGCTCAAGCGCAACCTGCTGGCGGCGCCGGATGACCCGGAGCTGCCGAAGAAT
CTGGTCCAGAAGCTGCGCCTGCGGCAGGGCCAGTACATCACCGCTTTCGCGCAGATGCGGGGCCACAAGGGCGTCATCCA
GAAGGTGGACACGGTGGACGGCCGGCCGCTCGAGGGCGCGCCGCGGCTGCCGCACTTCGCGGACCTGACGTCGGTGGACC
CCACCGAGCGGCTCAAGCTGGAGAACGGTCACAAGGAGATGGTGACCCGGGTGCTGGACCTCATCTCGCCCATTGGCAAG
GGCCAGCGCGCGCTCATCGTCGCCCCGCCCAAGACGGGCAAGACGATCATGCTCCAGCGCATCGCCCAGGCCATCCTCTC
CAACCACCCAGAGTGCCACGTCATGGTGGTGCTCATCGACGAGCGTCCAGAAGAAGTGACGGACATGCGGCGGGGCATCA
AGGCGGAGGTCCTGGCCTCCAGCTCCGACCGCCCCACCGCGGACCACCTCAAGGTGGCGGAGCTGGCCCTGGAGCGCGCG
CGCCGGCTGGTGGAGTCCGGCAAGGACGTGGTCGTCCTCCTGGACTCGATTACGCGTCTGGCCCGCGCCTTCAACAAGGA
GGTCGACAACTCCGGCCGCACCATGACCGGCGGCGTGGACAGCCGCGCCCTGGAGCGCCCCAAGCGCCTCTTCGGCGCCG
CCCGCGCGACGGAGGAGGCCGGCACGCTGACCATCATCGGCACGGCGCTCATCGACACCGGCAGCCGCATGGACGAGGTC
ATCTTCGAGGAGTTCAAGGGAACGGGTAACTCCGAGGTCACCCTGGACCGGCTCCTGGCGGAGAAGCGCGTCTTCCCGGC
CGTCAACATCGCCCAGTCCGGCACGCGCAAGGAGGAGAAGCTCTTCACCCTGCGCGAGTACGAGAAGGTGAAGAAGCTGC
GGCAGATGCTCTTCTCCGTGAAGCCGGTGGAGGCCATGGAGGCGCTCGTGAAGCGGCTGTCCCGCTACACGTACAACGAC
GAGTTCCTCGACGAGCTGTAG

Upstream 100 bases:

>100_bases
TGAATCAACAGGTGGGGGGTCGGCCGGACGACACCGCGCGAAAAAAGCGGCGGCGCCGTCCCCGGCCTCTGTTACTGTTA
CCCCTGCACTCCGGACGGCT

Downstream 100 bases:

>100_bases
TCCCCCGCTTCGGGAGTGGTACGGCGGGCCCGGGTGTGCGTTAAGGTGGCGGCATGATTCAAGGCTCGGGCCGCTGCCAC
TACCACCCGGAGCGCGCCGG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MGRQGAPGNGGSACSSPGPRVRFLSHGLSHLASPPSSWSGRPGRTQSGTFMSENPDNRDPRDAPPVPAARAVAPPEPDDD
GGDEGDDEGPDDGDSGGGAQGGAPGQPGQATGRRRRRRRRRRGAQVLFTPDGQAYRMQPGADGQQVQVFLTPQELEQYRQ
RQAQQQQQQQQPPQPAHGGGGQQHARHAQHGGGGQQASQQANLSPVEGVLDTEAKGPNAFLRQLKRNLLAAPDDPELPKN
LVQKLRLRQGQYITAFAQMRGHKGVIQKVDTVDGRPLEGAPRLPHFADLTSVDPTERLKLENGHKEMVTRVLDLISPIGK
GQRALIVAPPKTGKTIMLQRIAQAILSNHPECHVMVVLIDERPEEVTDMRRGIKAEVLASSSDRPTADHLKVAELALERA
RRLVESGKDVVVLLDSITRLARAFNKEVDNSGRTMTGGVDSRALERPKRLFGAARATEEAGTLTIIGTALIDTGSRMDEV
IFEEFKGTGNSEVTLDRLLAEKRVFPAVNIAQSGTRKEEKLFTLREYEKVKKLRQMLFSVKPVEAMEALVKRLSRYTYND
EFLDEL

Sequences:

>Translated_566_residues
MGRQGAPGNGGSACSSPGPRVRFLSHGLSHLASPPSSWSGRPGRTQSGTFMSENPDNRDPRDAPPVPAARAVAPPEPDDD
GGDEGDDEGPDDGDSGGGAQGGAPGQPGQATGRRRRRRRRRRGAQVLFTPDGQAYRMQPGADGQQVQVFLTPQELEQYRQ
RQAQQQQQQQQPPQPAHGGGGQQHARHAQHGGGGQQASQQANLSPVEGVLDTEAKGPNAFLRQLKRNLLAAPDDPELPKN
LVQKLRLRQGQYITAFAQMRGHKGVIQKVDTVDGRPLEGAPRLPHFADLTSVDPTERLKLENGHKEMVTRVLDLISPIGK
GQRALIVAPPKTGKTIMLQRIAQAILSNHPECHVMVVLIDERPEEVTDMRRGIKAEVLASSSDRPTADHLKVAELALERA
RRLVESGKDVVVLLDSITRLARAFNKEVDNSGRTMTGGVDSRALERPKRLFGAARATEEAGTLTIIGTALIDTGSRMDEV
IFEEFKGTGNSEVTLDRLLAEKRVFPAVNIAQSGTRKEEKLFTLREYEKVKKLRQMLFSVKPVEAMEALVKRLSRYTYND
EFLDEL
>Mature_565_residues
GRQGAPGNGGSACSSPGPRVRFLSHGLSHLASPPSSWSGRPGRTQSGTFMSENPDNRDPRDAPPVPAARAVAPPEPDDDG
GDEGDDEGPDDGDSGGGAQGGAPGQPGQATGRRRRRRRRRRGAQVLFTPDGQAYRMQPGADGQQVQVFLTPQELEQYRQR
QAQQQQQQQQPPQPAHGGGGQQHARHAQHGGGGQQASQQANLSPVEGVLDTEAKGPNAFLRQLKRNLLAAPDDPELPKNL
VQKLRLRQGQYITAFAQMRGHKGVIQKVDTVDGRPLEGAPRLPHFADLTSVDPTERLKLENGHKEMVTRVLDLISPIGKG
QRALIVAPPKTGKTIMLQRIAQAILSNHPECHVMVVLIDERPEEVTDMRRGIKAEVLASSSDRPTADHLKVAELALERAR
RLVESGKDVVVLLDSITRLARAFNKEVDNSGRTMTGGVDSRALERPKRLFGAARATEEAGTLTIIGTALIDTGSRMDEVI
FEEFKGTGNSEVTLDRLLAEKRVFPAVNIAQSGTRKEEKLFTLREYEKVKKLRQMLFSVKPVEAMEALVKRLSRYTYNDE
FLDEL

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=368, Percent_Identity=50.8152173913043, Blast_Score=347, Evalue=1e-96,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 61836; Mature: 61704

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRQGAPGNGGSACSSPGPRVRFLSHGLSHLASPPSSWSGRPGRTQSGTFMSENPDNRDP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RDAPPVPAARAVAPPEPDDDGGDEGDDEGPDDGDSGGGAQGGAPGQPGQATGRRRRRRRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RRGAQVLFTPDGQAYRMQPGADGQQVQVFLTPQELEQYRQRQAQQQQQQQQPPQPAHGGG
HCCCEEEECCCCCEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQQHARHAQHGGGGQQASQQANLSPVEGVLDTEAKGPNAFLRQLKRNLLAAPDDPELPKN
CHHHHHHHHCCCCCHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHH
LVQKLRLRQGQYITAFAQMRGHKGVIQKVDTVDGRPLEGAPRLPHFADLTSVDPTERLKL
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCC
ENGHKEMVTRVLDLISPIGKGQRALIVAPPKTGKTIMLQRIAQAILSNHPECHVMVVLID
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEC
ERPEEVTDMRRGIKAEVLASSSDRPTADHLKVAELALERARRLVESGKDVVVLLDSITRL
CCCHHHHHHHCCCCEEEHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
ARAFNKEVDNSGRTMTGGVDSRALERPKRLFGAARATEEAGTLTIIGTALIDTGSRMDEV
HHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCHHHHH
IFEEFKGTGNSEVTLDRLLAEKRVFPAVNIAQSGTRKEEKLFTLREYEKVKKLRQMLFSV
HHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KPVEAMEALVKRLSRYTYNDEFLDEL
CCHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
GRQGAPGNGGSACSSPGPRVRFLSHGLSHLASPPSSWSGRPGRTQSGTFMSENPDNRDP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RDAPPVPAARAVAPPEPDDDGGDEGDDEGPDDGDSGGGAQGGAPGQPGQATGRRRRRRRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RRGAQVLFTPDGQAYRMQPGADGQQVQVFLTPQELEQYRQRQAQQQQQQQQPPQPAHGGG
HCCCEEEECCCCCEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQQHARHAQHGGGGQQASQQANLSPVEGVLDTEAKGPNAFLRQLKRNLLAAPDDPELPKN
CHHHHHHHHCCCCCHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHH
LVQKLRLRQGQYITAFAQMRGHKGVIQKVDTVDGRPLEGAPRLPHFADLTSVDPTERLKL
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCC
ENGHKEMVTRVLDLISPIGKGQRALIVAPPKTGKTIMLQRIAQAILSNHPECHVMVVLID
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEC
ERPEEVTDMRRGIKAEVLASSSDRPTADHLKVAELALERARRLVESGKDVVVLLDSITRL
CCCHHHHHHHCCCCEEEHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
ARAFNKEVDNSGRTMTGGVDSRALERPKRLFGAARATEEAGTLTIIGTALIDTGSRMDEV
HHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCHHHHH
IFEEFKGTGNSEVTLDRLLAEKRVFPAVNIAQSGTRKEEKLFTLREYEKVKKLRQMLFSV
HHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KPVEAMEALVKRLSRYTYNDEFLDEL
CCHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]