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The map label for this gene is atoS [H]

Identifier: 108757476

GI number: 108757476

Start: 5984971

End: 5986620

Strand: Reverse

Name: atoS [H]

Synonym: MXAN_4786

Alternate gene names: 108757476

Gene position: 5986620-5984971 (Counterclockwise)

Preceding gene: 108759237

Following gene: 108759138

Centisome position: 65.5

GC content: 71.39

Gene sequence:

>1650_bases
ATGACTTCCGCCCACCTGCCGCCAACACCACCGCCACTGCCGACGCTGACCCCCACGCCGGGTGAGCTGGCCCACGCGCA
GCGGCGCGGGGGGCGCTCCGCGCTCGTCGGTCTGGGGCTGGTGGGGCTGGTGGCGCTGACGAGCCCCGTGCTGGGCTACG
TGGAGGACGTGCGCAACGCGCGCGAGGAGCTGCTGAGCCGGCTGCTCAACCAGGCGCAGGTGCAGTCGGAGGCGCTGGGC
GTCCACCTGGGGCTGTTGGAGGCGGAGCTGGCCCGCGTGGCCGGGCACCCCGCGCTGTCTCCTGAGGACGGCGCCTCCCC
GGCGGAGCTGGCCCTGCTGGAGAGCGCCTTCTACCATTCGTCCCTCTTCTCGGAGGGCGTGGCCCTGCTGACGCCCGCGG
GCGAGCGCGTCTGGAGCGACCCTCCGGACATGCCGCTGGGGCGCTCGCCGCTGACGCTGCGGCCCTGGTTCCGCCGGATG
GTGGAGGGCCGCCAGCCGGAAATCGACCTGCTGGAAGGGGAGGGGGGGCCCATCGTGGTCGCCGTCCCCATGTTCCAGGA
GGGCCGCTTCAAGGGTGTGCTGCTGGGAGAGCTCCGCGCCAGCGCGCTGCCCACGCGGCCCACCGCGCAGACGTCACTGG
TGCTGATGGATGACCAGGGTCAGATCCTGATGCCAGTGGGGTTCAATCTGGGCGCCGGGGACATCACGGGGGGGCTGCGC
GCGCTGGCGAACATGCCGGGGCCGCTGACGCTGGATGACAAGCACATGATGGGCGCGGGCGCGTGGGTGGGGAAGAGCGA
CCTGCTGTTGGTCGTCCTGGAGGAGGAGACGGCCACCGCGGGCCTCCGGGCGCGCTTCCTGCGGCAGCTGGCGTTCCACA
TCGCCCTGCTGAGCAGCACGCTCATCATCTTCATCCTCCTGCTGCGGCACTCCTACCGTTCGCTGCTGGCGGCCGAGGAG
CGGCTGCGACGCCAGGAGACCATGGCGGCGCTGGGGACCGCGGCCTCGCTCATCGCGCATGAGGTGAAGAACGCCCTCAA
CGGCATCCAGGCCGCGCTGTCCGTGCTCCGGCATACCCCCGCGGGCAGCGAGCTGCCCGTGGGCGCGCTGCGCTCGCAGG
TGGAGCGCTTGAGCCATCTGGCGCGCTCGCTGCTGTCCTTCGGGGCGCCTCGTGCCGCGCTGCGCCGCCGCTGCGAGGTG
CACCTGCTGGTGAAGGACGCGCTCCAGGGCGTGAAGCTGCTGCCGGAGTCAGAGGCCGTGGCACTGACTACGTCCCTGGA
GGAGTCCCTGTGGGTCCAGGGGGATGCGGCGCTGCTGGTGTCCGCCATCGACAACGTGTTGCGCAACGCGGTGGAGGCAG
GCGCGGTGGCGAAGGACACAGGGATGCAGTTGGCACCGTGGGTCAGCGTGAGTCTGACGCGGGACGAACATGACGCCGTG
CTCGTGGTGGAGGACAATGCGGGCGGCGTGGATCCGCGTCTCGAGCCCAGGTTGTGGGAACCTTTCGCCACCGGGCGGGC
GAAGGGCGTGGGGCTGGGACTGCCCATGGCGCGTGCCTCCGTGGAGGCCCATGGTGGCAGTCTGAACTATGTCCGGAGTC
CGCTGGGAAGCCGCTTCACGCTGCGCCTTCCGTTGGAGGTGGCCCGATGA

Upstream 100 bases:

>100_bases
GGGGCGATGGCCGGCCCTCCAGCGGGCGGGCCCCTGGCCAGGTGGCCTGATTGCGCGTGAAGGTGCTTCCGCGCCGAGGT
AAACCCCAGGGAGCTCTGTC

Downstream 100 bases:

>100_bases
GCACCTATCTGTTGCTGGTCGATGACGACCGGACCTTCGCCTCGCTGGCGGCCTCCGTGCTGCGACACGAGGGCTTCCGC
GTCACGCTGGCGCATTCACT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTSAHLPPTPPPLPTLTPTPGELAHAQRRGGRSALVGLGLVGLVALTSPVLGYVEDVRNAREELLSRLLNQAQVQSEALG
VHLGLLEAELARVAGHPALSPEDGASPAELALLESAFYHSSLFSEGVALLTPAGERVWSDPPDMPLGRSPLTLRPWFRRM
VEGRQPEIDLLEGEGGPIVVAVPMFQEGRFKGVLLGELRASALPTRPTAQTSLVLMDDQGQILMPVGFNLGAGDITGGLR
ALANMPGPLTLDDKHMMGAGAWVGKSDLLLVVLEEETATAGLRARFLRQLAFHIALLSSTLIIFILLLRHSYRSLLAAEE
RLRRQETMAALGTAASLIAHEVKNALNGIQAALSVLRHTPAGSELPVGALRSQVERLSHLARSLLSFGAPRAALRRRCEV
HLLVKDALQGVKLLPESEAVALTTSLEESLWVQGDAALLVSAIDNVLRNAVEAGAVAKDTGMQLAPWVSVSLTRDEHDAV
LVVEDNAGGVDPRLEPRLWEPFATGRAKGVGLGLPMARASVEAHGGSLNYVRSPLGSRFTLRLPLEVAR

Sequences:

>Translated_549_residues
MTSAHLPPTPPPLPTLTPTPGELAHAQRRGGRSALVGLGLVGLVALTSPVLGYVEDVRNAREELLSRLLNQAQVQSEALG
VHLGLLEAELARVAGHPALSPEDGASPAELALLESAFYHSSLFSEGVALLTPAGERVWSDPPDMPLGRSPLTLRPWFRRM
VEGRQPEIDLLEGEGGPIVVAVPMFQEGRFKGVLLGELRASALPTRPTAQTSLVLMDDQGQILMPVGFNLGAGDITGGLR
ALANMPGPLTLDDKHMMGAGAWVGKSDLLLVVLEEETATAGLRARFLRQLAFHIALLSSTLIIFILLLRHSYRSLLAAEE
RLRRQETMAALGTAASLIAHEVKNALNGIQAALSVLRHTPAGSELPVGALRSQVERLSHLARSLLSFGAPRAALRRRCEV
HLLVKDALQGVKLLPESEAVALTTSLEESLWVQGDAALLVSAIDNVLRNAVEAGAVAKDTGMQLAPWVSVSLTRDEHDAV
LVVEDNAGGVDPRLEPRLWEPFATGRAKGVGLGLPMARASVEAHGGSLNYVRSPLGSRFTLRLPLEVAR
>Mature_548_residues
TSAHLPPTPPPLPTLTPTPGELAHAQRRGGRSALVGLGLVGLVALTSPVLGYVEDVRNAREELLSRLLNQAQVQSEALGV
HLGLLEAELARVAGHPALSPEDGASPAELALLESAFYHSSLFSEGVALLTPAGERVWSDPPDMPLGRSPLTLRPWFRRMV
EGRQPEIDLLEGEGGPIVVAVPMFQEGRFKGVLLGELRASALPTRPTAQTSLVLMDDQGQILMPVGFNLGAGDITGGLRA
LANMPGPLTLDDKHMMGAGAWVGKSDLLLVVLEEETATAGLRARFLRQLAFHIALLSSTLIIFILLLRHSYRSLLAAEER
LRRQETMAALGTAASLIAHEVKNALNGIQAALSVLRHTPAGSELPVGALRSQVERLSHLARSLLSFGAPRAALRRRCEVH
LLVKDALQGVKLLPESEAVALTTSLEESLWVQGDAALLVSAIDNVLRNAVEAGAVAKDTGMQLAPWVSVSLTRDEHDAVL
VVEDNAGGVDPRLEPRLWEPFATGRAKGVGLGLPMARASVEAHGGSLNYVRSPLGSRFTLRLPLEVAR

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=27.5720164609054, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=27.1698113207547, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=28.0851063829787, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58508; Mature: 58377

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAHLPPTPPPLPTLTPTPGELAHAQRRGGRSALVGLGLVGLVALTSPVLGYVEDVRNA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REELLSRLLNQAQVQSEALGVHLGLLEAELARVAGHPALSPEDGASPAELALLESAFYHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
SLFSEGVALLTPAGERVWSDPPDMPLGRSPLTLRPWFRRMVEGRQPEIDLLEGEGGPIVV
HHHHCCEEEEECCCCHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEE
AVPMFQEGRFKGVLLGELRASALPTRPTAQTSLVLMDDQGQILMPVGFNLGAGDITGGLR
EECCCCCCCCCEEEEHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHHHHHH
ALANMPGPLTLDDKHMMGAGAWVGKSDLLLVVLEEETATAGLRARFLRQLAFHIALLSST
HHHCCCCCCEECCCHHCCCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LIIFILLLRHSYRSLLAAEERLRRQETMAALGTAASLIAHEVKNALNGIQAALSVLRHTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGSELPVGALRSQVERLSHLARSLLSFGAPRAALRRRCEVHLLVKDALQGVKLLPESEAV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEHHHHHHHHHEECCCCCCE
ALTTSLEESLWVQGDAALLVSAIDNVLRNAVEAGAVAKDTGMQLAPWVSVSLTRDEHDAV
EEEEHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEEECCCCEE
LVVEDNAGGVDPRLEPRLWEPFATGRAKGVGLGLPMARASVEAHGGSLNYVRSPLGSRFT
EEEECCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCEEE
LRLPLEVAR
EEECHHCCC
>Mature Secondary Structure 
TSAHLPPTPPPLPTLTPTPGELAHAQRRGGRSALVGLGLVGLVALTSPVLGYVEDVRNA
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REELLSRLLNQAQVQSEALGVHLGLLEAELARVAGHPALSPEDGASPAELALLESAFYHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
SLFSEGVALLTPAGERVWSDPPDMPLGRSPLTLRPWFRRMVEGRQPEIDLLEGEGGPIVV
HHHHCCEEEEECCCCHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEE
AVPMFQEGRFKGVLLGELRASALPTRPTAQTSLVLMDDQGQILMPVGFNLGAGDITGGLR
EECCCCCCCCCEEEEHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHHHHHH
ALANMPGPLTLDDKHMMGAGAWVGKSDLLLVVLEEETATAGLRARFLRQLAFHIALLSST
HHHCCCCCCEECCCHHCCCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LIIFILLLRHSYRSLLAAEERLRRQETMAALGTAASLIAHEVKNALNGIQAALSVLRHTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGSELPVGALRSQVERLSHLARSLLSFGAPRAALRRRCEVHLLVKDALQGVKLLPESEAV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEHHHHHHHHHEECCCCCCE
ALTTSLEESLWVQGDAALLVSAIDNVLRNAVEAGAVAKDTGMQLAPWVSVSLTRDEHDAV
EEEEHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEEECCCCEE
LVVEDNAGGVDPRLEPRLWEPFATGRAKGVGLGLPMARASVEAHGGSLNYVRSPLGSRFT
EEEECCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCEEE
LRLPLEVAR
EEECHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]