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The map label for this gene is dtd

Identifier: 108757378

GI number: 108757378

Start: 1244659

End: 1245120

Strand: Reverse

Name: dtd

Synonym: MXAN_1068

Alternate gene names: 108757378

Gene position: 1245120-1244659 (Counterclockwise)

Preceding gene: 108758097

Following gene: 108758786

Centisome position: 13.62

GC content: 70.35

Gene sequence:

>462_bases
ATGAGAGCGGTGGTGCAGCGCGTGCTGGAGGCGTCGGTGACGGTGGAGGGCCAGCGCGTGAGCGACATCGGCCCGGGCCT
GCTGGTGCTGCTGGGCGTGGGCAAGGGCGACACGGAGGCGGACGTGGCGTGGATGGTGGAGAAGCTGGCCACGCTGCGCA
TCTTCGAGGACGCCGCCGGGAAGATGAACCTGTCGCTGGAGGAGACGTCCCGGCAGCTCATCGTCGTCAGCCAGTTCACG
CTCTACGGCGACGCGCGCAAGGGGCGCAGGCCCAGCTTCATCGACGCGATGGAGCCCGTGAGCGCCAAGGCCCTCTATGA
GCGCACCTGTGAGCTGCTGCGCCAGCGCGGCCTGAGCGTGGGCACCGGCATCTTCGCCGCGGACATGAAGGTGGCGCTCG
TCAACGACGGCCCCGTCACGCTGCTGCTGGAGAGCCCCGGGCCGGCCGCGCCCAAAGGCTAG

Upstream 100 bases:

>100_bases
GCGCTCGCTCTTCCAGCAGGCGGAAACCTGACATTCCAACTGTAACGGCGTGACTGACGCGAGCCCCCGGTCAGACACGC
TTGTCCACGAGGTGACTTCG

Downstream 100 bases:

>100_bases
ATTCGGACGCCGGAGCCCTTCGTCACCAGCGCCGCCAGCCCCTGCTTCGCCAGCGCCGCGCCGCGAAGGTGCGCGGTGAG
GGCACCCAGCTCGCGAATCC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MRAVVQRVLEASVTVEGQRVSDIGPGLLVLLGVGKGDTEADVAWMVEKLATLRIFEDAAGKMNLSLEETSRQLIVVSQFT
LYGDARKGRRPSFIDAMEPVSAKALYERTCELLRQRGLSVGTGIFAADMKVALVNDGPVTLLLESPGPAAPKG

Sequences:

>Translated_153_residues
MRAVVQRVLEASVTVEGQRVSDIGPGLLVLLGVGKGDTEADVAWMVEKLATLRIFEDAAGKMNLSLEETSRQLIVVSQFT
LYGDARKGRRPSFIDAMEPVSAKALYERTCELLRQRGLSVGTGIFAADMKVALVNDGPVTLLLESPGPAAPKG
>Mature_153_residues
MRAVVQRVLEASVTVEGQRVSDIGPGLLVLLGVGKGDTEADVAWMVEKLATLRIFEDAAGKMNLSLEETSRQLIVVSQFT
LYGDARKGRRPSFIDAMEPVSAKALYERTCELLRQRGLSVGTGIFAADMKVALVNDGPVTLLLESPGPAAPKG

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=151, Percent_Identity=45.0331125827815, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=51.3888888888889, Blast_Score=141, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=39.8648648648649, Blast_Score=99, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=37.1621621621622, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281361569, Length=148, Percent_Identity=44.5945945945946, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_MYXXD (Q1DDE5)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_629328.1
- ProteinModelPortal:   Q1DDE5
- SMR:   Q1DDE5
- STRING:   Q1DDE5
- GeneID:   4100519
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_1068
- TIGR:   MXAN_1068
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q1DDE5
- ProtClustDB:   PRK05273
- BioCyc:   MXAN246197:MXAN_1068-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16370; Mature: 16370

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVQRVLEASVTVEGQRVSDIGPGLLVLLGVGKGDTEADVAWMVEKLATLRIFEDAAG
CHHHHHHHHHHHCEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
KMNLSLEETSRQLIVVSQFTLYGDARKGRRPSFIDAMEPVSAKALYERTCELLRQRGLSV
CEEEEHHCCCCEEEEEEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GTGIFAADMKVALVNDGPVTLLLESPGPAAPKG
CCCEEEECEEEEEECCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MRAVVQRVLEASVTVEGQRVSDIGPGLLVLLGVGKGDTEADVAWMVEKLATLRIFEDAAG
CHHHHHHHHHHHCEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
KMNLSLEETSRQLIVVSQFTLYGDARKGRRPSFIDAMEPVSAKALYERTCELLRQRGLSV
CEEEEHHCCCCEEEEEEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GTGIFAADMKVALVNDGPVTLLLESPGPAAPKG
CCCEEEECEEEEEECCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA