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The map label for this gene is ribD [H]

Identifier: 108757223

GI number: 108757223

Start: 5965155

End: 5966318

Strand: Reverse

Name: ribD [H]

Synonym: MXAN_4764

Alternate gene names: 108757223

Gene position: 5966318-5965155 (Counterclockwise)

Preceding gene: 108760844

Following gene: 108758043

Centisome position: 65.28

GC content: 72.08

Gene sequence:

>1164_bases
ATGCGGCTGTTGACACGGGCAAGGTTGGAAGCGACACGGGCGCCCCGGGCGAAGCGAGCGGCGGACTTCGACCGGGCGGT
GGCTGAGTTCTTCATGCGCATCGCGCTGGAGGAAGCCGCCAAGGGCCTGGGCCGCACCAGCCCCAACCCCGTCGTGGGCG
CGGTGCTGGTGAAGGGCGGGCGCATCATCGCCCGCGGCTACCACAAGAAGGCGGGCAGCGCGCACGCGGAGGTCGTCGCG
CTGGAGGCCGCCGGTGCGCGCGCCAAGGGCGCGGACCTCTACACCACGCTGGAGCCGTGCGACCACTACGGGCGTACCCC
GCCGTGCAGCATGGCCATCATCGAGGCGGGCGTCCGGCGCGTCATCTGCGCGTCGGCGGACCCCAACCCGAAGGTGAGCG
GCAAGGGCGTGTCGCGGATGCGGCGCGCCGGCCTCAAGGTCCTCACGGGCGTGCTCGCGGAGGATGCGGACCGCCTCAAC
CGGCCCTTCTTCAAGATGATCCGCACGGGCCTGCCCTGGGTGACGCTCAAGGCGGCGGTGACGCTGGACGGGAAGCTGGC
CACCGCGACTGGTGACTCGCGCTGGGTGACGGGGGCGCCGGCGCGCGCCTGGGTCCACCGGCTGCGGGACTCGGTGGACG
TCATCCTGGTGGGCGCCAACACTGTCCGGAAGGACGACCCGAAGCTGACCACGCGGCTGCCCGGAGGCGGCGGGAAGGAC
CCGCTGCGCGTGGTGGTGGACAGCCACCTGCGCCTTTCCCCGGGCTACACCATCTTCACGCAGCGCAGCGCCGCGCGCAC
CGTGGTGGCCACGCTGGAGGATCCGGAGGGCCGCAAGGCGCGGCGCTTCCTGGCCCAGGGTGTGGACGTCTGGCAGCTCC
GCGAGAAGGCGGGACAGGTGGACCTCAAGGCCCTGCTGCGGCGGCTGGCGAAGGGCGGCCACAACCACGTCATGGTGGAG
GGCGGCGCGGAGATGTACGGCTCCTTCCTGCGTGGGCGCCTGGCGGATTCGCTGGCGCTGTTCCTGGCGCCCAAGCTGAT
TGGCAGCCCGGGCCTGTCGTGGGCCGGCGACCTGGGGGTGAAGGAGATGGCCCAGGCCCTGGCGGTGAAGGACCTCGCCT
TCGAACGCCATGGCGACGACATCCTGCTCCAGGCGCTGTTGTAG

Upstream 100 bases:

>100_bases
GTTCATGGACGAGCTGAAGGCCCTGCGCGAGGCGGAGGCGCGCGAGCAGCGCCAGGCGCCTCCCTCGGCACCGGTGGACA
AGGGCGGTTAGAGAAAGCAC

Downstream 100 bases:

>100_bases
GACACGAGCGGCCGTGGGCGCAGGCGGGGCCGGTCCGTTATAAGCGGCCCCATGTTTACCGGCCTCATTCAGGACCTTGG
CAGGGTGGAGCGCGTCATTC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MRLLTRARLEATRAPRAKRAADFDRAVAEFFMRIALEEAAKGLGRTSPNPVVGAVLVKGGRIIARGYHKKAGSAHAEVVA
LEAAGARAKGADLYTTLEPCDHYGRTPPCSMAIIEAGVRRVICASADPNPKVSGKGVSRMRRAGLKVLTGVLAEDADRLN
RPFFKMIRTGLPWVTLKAAVTLDGKLATATGDSRWVTGAPARAWVHRLRDSVDVILVGANTVRKDDPKLTTRLPGGGGKD
PLRVVVDSHLRLSPGYTIFTQRSAARTVVATLEDPEGRKARRFLAQGVDVWQLREKAGQVDLKALLRRLAKGGHNHVMVE
GGAEMYGSFLRGRLADSLALFLAPKLIGSPGLSWAGDLGVKEMAQALAVKDLAFERHGDDILLQALL

Sequences:

>Translated_387_residues
MRLLTRARLEATRAPRAKRAADFDRAVAEFFMRIALEEAAKGLGRTSPNPVVGAVLVKGGRIIARGYHKKAGSAHAEVVA
LEAAGARAKGADLYTTLEPCDHYGRTPPCSMAIIEAGVRRVICASADPNPKVSGKGVSRMRRAGLKVLTGVLAEDADRLN
RPFFKMIRTGLPWVTLKAAVTLDGKLATATGDSRWVTGAPARAWVHRLRDSVDVILVGANTVRKDDPKLTTRLPGGGGKD
PLRVVVDSHLRLSPGYTIFTQRSAARTVVATLEDPEGRKARRFLAQGVDVWQLREKAGQVDLKALLRRLAKGGHNHVMVE
GGAEMYGSFLRGRLADSLALFLAPKLIGSPGLSWAGDLGVKEMAQALAVKDLAFERHGDDILLQALL
>Mature_387_residues
MRLLTRARLEATRAPRAKRAADFDRAVAEFFMRIALEEAAKGLGRTSPNPVVGAVLVKGGRIIARGYHKKAGSAHAEVVA
LEAAGARAKGADLYTTLEPCDHYGRTPPCSMAIIEAGVRRVICASADPNPKVSGKGVSRMRRAGLKVLTGVLAEDADRLN
RPFFKMIRTGLPWVTLKAAVTLDGKLATATGDSRWVTGAPARAWVHRLRDSVDVILVGANTVRKDDPKLTTRLPGGGGKD
PLRVVVDSHLRLSPGYTIFTQRSAARTVVATLEDPEGRKARRFLAQGVDVWQLREKAGQVDLKALLRRLAKGGHNHVMVE
GGAEMYGSFLRGRLADSLALFLAPKLIGSPGLSWAGDLGVKEMAQALAVKDLAFERHGDDILLQALL

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=370, Percent_Identity=40, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=32.4675324675325, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 41632; Mature: 41632

Theoretical pI: Translated: 10.99; Mature: 10.99

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLTRARLEATRAPRAKRAADFDRAVAEFFMRIALEEAAKGLGRTSPNPVVGAVLVKGG
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
RIIARGYHKKAGSAHAEVVALEAAGARAKGADLYTTLEPCDHYGRTPPCSMAIIEAGVRR
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCHHHHCCCCCCHHHHHHHHHHHE
VICASADPNPKVSGKGVSRMRRAGLKVLTGVLAEDADRLNRPFFKMIRTGLPWVTLKAAV
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEEE
TLDGKLATATGDSRWVTGAPARAWVHRLRDSVDVILVGANTVRKDDPKLTTRLPGGGGKD
EECCEEEECCCCCCEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECCCCCCCC
PLRVVVDSHLRLSPGYTIFTQRSAARTVVATLEDPEGRKARRFLAQGVDVWQLREKAGQV
HHEEEECCCEEECCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCC
DLKALLRRLAKGGHNHVMVEGGAEMYGSFLRGRLADSLALFLAPKLIGSPGLSWAGDLGV
CHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
KEMAQALAVKDLAFERHGDDILLQALL
HHHHHHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure
MRLLTRARLEATRAPRAKRAADFDRAVAEFFMRIALEEAAKGLGRTSPNPVVGAVLVKGG
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
RIIARGYHKKAGSAHAEVVALEAAGARAKGADLYTTLEPCDHYGRTPPCSMAIIEAGVRR
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCHHHHCCCCCCHHHHHHHHHHHE
VICASADPNPKVSGKGVSRMRRAGLKVLTGVLAEDADRLNRPFFKMIRTGLPWVTLKAAV
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEEE
TLDGKLATATGDSRWVTGAPARAWVHRLRDSVDVILVGANTVRKDDPKLTTRLPGGGGKD
EECCEEEECCCCCCEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECCCCCCCC
PLRVVVDSHLRLSPGYTIFTQRSAARTVVATLEDPEGRKARRFLAQGVDVWQLREKAGQV
HHEEEECCCEEECCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCC
DLKALLRRLAKGGHNHVMVEGGAEMYGSFLRGRLADSLALFLAPKLIGSPGLSWAGDLGV
CHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
KEMAQALAVKDLAFERHGDDILLQALL
HHHHHHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]