Click here to switch to the map view.

The map label for this gene is phoR [H]

Identifier: 108757104

GI number: 108757104

Start: 358250

End: 360394

Strand: Reverse

Name: phoR [H]

Synonym: MXAN_0304

Alternate gene names: 108757104

Gene position: 360394-358250 (Counterclockwise)

Preceding gene: 108763250

Following gene: 108757429

Centisome position: 3.94

GC content: 69.04

Gene sequence:

>2145_bases
GTGCGCGGCTCCTCCCCAGCGGTATGCATGCAGCCGGCCGGGAGCCCGCCCCTGACCATGCACGCTCGTCCGGAACGACA
TCACCCACTCTGGGCTTCACGCGCCGGACGTTATGGCGTCGCGCTCCTCGCCTTCGTCGCGGCGTGGCTCATCCAGGCGG
GCACGATGTCGTTCATCCCAGCCACCCCGTTCCTGTTCTTCTTCGGCGCGGTGATGGTGTCCGGCTGGTGGGGTGGCTGG
GGCCCCGCCCTGGCGACGACGCTCCTGTCGGTGGTGGTGGTGGACTTCTACTTCCTGGAGCCACTGCTCAACCTGATGCC
GGGCACGGGAGGGGCTGTCTCGCTGGCGGTCTTCGTCGTGCTCGCGCTGCTGATGACGAAGCTGAACGTCATGCTGCGCA
AGGCCAACGCGGAGCGGGCGCGACTGCTGGAGCGGGAGCGGGCAGCCCGAAGCGAGGCGGAGGCCGGGCAGGCACGGCTC
CACGCGCTCTTCCGGGACGCGCCCGCCGCCATCATCCTCATGCATGGCCCCCGGCACATCTATTCCTTCTCCAACACGAT
GAACAACACACTGATGGGGACGGACACGCTGGTGGGCCAGGAGGCGAGCAAGGCCCTGCCGTGGGCGGAGTCGCGAGGCT
TCATCACCCTGCTGGACGAGGTCTACCGCACCGGCGTCCCTTTCACGGGCAATGCGGTGCCGTTCCCTCGCAAGCCCCCC
CATGACGAGATACAGGAGACGTATCTCAACATCGTGTATCAGCCCACGCGGAACGAGCAGGGTGAGGTCGACGGCATCGC
CGGCTTCGGTTTCGACGTGACGGACCTGGTCCGGGCCCGACAGCGCGCCGAGGCCCTGACGCACGAGCTCCAGCTCGCCG
AGGCACGTGACTGGCTCCTCGCGGAGTCGGGCGCGGTGCTGGCGTCATCGCTCGACGACGAGACGACGCTGCGGAACATG
GCGAAGCTGGTGGTGCCCACGTTCGCGGACTGGTGCCTCGTCGACGTGGCGGAGCCGGATGGGACGTTCCGGCGACTGGA
GGCGGCACACTTCCGGCTCGAGGACGACGCGCTGGCCGAGGACATCCTCCGCTTCGGAATGCAGCCCAGCGGCAATCCGG
GGCATCCCCCCACGGGCGCCCTGCTGAAGGCGGAGACGGTTCACGTCGAGCGGTTGACCCGGGAACGGATTCACGAGCTC
GCACACGACGCGGAACACGCCCGGGTGCTGGAAGCGATAGGGCCCGTCTCCTTCATCGCCGTGCCCTTGATTGCACGCGG
ACAGGTGTTGGGGGTGCTCAGCTTCATCCACGCCCACTCCGGCCGGCATTACTCGACGTCAGACCTGGCGTTCGCCAAGG
AACTGGCACACCGGGCCGCGCTCTCCCTGGAGAATGCCCGGCTCTATGCGGAGGCTCGGGAGGCCATCCGCCTGCGCGAT
GAGTTCATGTCCATTGCCAGCCACGAACTGAAGACGCCGCTCACCCCGCTGAGCCTGAAGCTCCAGGCGCTCTCGCGGGA
GCTGGCCCGCCACCCGGGCCCGGTTCCTCGCAACCTGGTGGAGAGCTACGTGGCGGTGGGCGCACGGCAGGTGCAGAAGC
TGGCGGAGCTGGTGGGCGACCTGCTCGACGTGTCGCGCATCTCCGCGGGGCGGCTCTCGCTGGAGTTGGAGGAGCTCGAG
CTGGGGTCGCTCGTCCGGGACGTCGTCACCCGGTATGAACCCCAGGCCGCGCGCACCGGCTCCCCCTTGCAGTTGGAGGC
GGGAGACTTCGACATCGTGGGCCGGTGGGACCGGCTGCGTCTGGAGCAGGTCATCACCAACCTGGTGGACAACGCCGTGA
AGTACGGCAACGGCAGGCCCATCCACGTGCGCCTGGAGCCGCATGACGGCGGAGCGCGGCTGACGGTGCGGGACGAGGGC
ATCGGCATCGAGCCCCAGCATCTGCCCCGCCTCTTCGGCCGCTTCGAACGCGCCGTGTCCGAGCGCAACTACGGGGGCCT
GGGCCTGGGCCTGTACATCACCCGCACGCTGGTGGAGGCCATGGGCGGCCGGGTCCACGTGGAGAGCAGGCTGGGGCGAG
GCTCCACCTTCACCGTGGAGCTGCCCAGCCACCTGGGCGCGGAGCAGGCCCGTCAAGCCCCCTGA

Upstream 100 bases:

>100_bases
GCACCAAGCCACAGCCGTTCCGCCGGCTGCGCTGAGCAGCCTTGCATGACAGCGCGGCGAGCAAGATGTCATGCAGTGGG
TTCCGGTGCTTACCTGAGAA

Downstream 100 bases:

>100_bases
CTGTCGTTTCCAGGCTCGAAGGTCATGCGAAGCCGGGAGTCTCCAGTTAGAGGGGCGTCACCACGAGGAAGGAGCGAGGG
ACATGGAGACTCGGAAGCTG

Product: putative sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 714

Protein sequence:

>714_residues
MRGSSPAVCMQPAGSPPLTMHARPERHHPLWASRAGRYGVALLAFVAAWLIQAGTMSFIPATPFLFFFGAVMVSGWWGGW
GPALATTLLSVVVVDFYFLEPLLNLMPGTGGAVSLAVFVVLALLMTKLNVMLRKANAERARLLERERAARSEAEAGQARL
HALFRDAPAAIILMHGPRHIYSFSNTMNNTLMGTDTLVGQEASKALPWAESRGFITLLDEVYRTGVPFTGNAVPFPRKPP
HDEIQETYLNIVYQPTRNEQGEVDGIAGFGFDVTDLVRARQRAEALTHELQLAEARDWLLAESGAVLASSLDDETTLRNM
AKLVVPTFADWCLVDVAEPDGTFRRLEAAHFRLEDDALAEDILRFGMQPSGNPGHPPTGALLKAETVHVERLTRERIHEL
AHDAEHARVLEAIGPVSFIAVPLIARGQVLGVLSFIHAHSGRHYSTSDLAFAKELAHRAALSLENARLYAEAREAIRLRD
EFMSIASHELKTPLTPLSLKLQALSRELARHPGPVPRNLVESYVAVGARQVQKLAELVGDLLDVSRISAGRLSLELEELE
LGSLVRDVVTRYEPQAARTGSPLQLEAGDFDIVGRWDRLRLEQVITNLVDNAVKYGNGRPIHVRLEPHDGGARLTVRDEG
IGIEPQHLPRLFGRFERAVSERNYGGLGLGLYITRTLVEAMGGRVHVESRLGRGSTFTVELPSHLGAEQARQAP

Sequences:

>Translated_714_residues
MRGSSPAVCMQPAGSPPLTMHARPERHHPLWASRAGRYGVALLAFVAAWLIQAGTMSFIPATPFLFFFGAVMVSGWWGGW
GPALATTLLSVVVVDFYFLEPLLNLMPGTGGAVSLAVFVVLALLMTKLNVMLRKANAERARLLERERAARSEAEAGQARL
HALFRDAPAAIILMHGPRHIYSFSNTMNNTLMGTDTLVGQEASKALPWAESRGFITLLDEVYRTGVPFTGNAVPFPRKPP
HDEIQETYLNIVYQPTRNEQGEVDGIAGFGFDVTDLVRARQRAEALTHELQLAEARDWLLAESGAVLASSLDDETTLRNM
AKLVVPTFADWCLVDVAEPDGTFRRLEAAHFRLEDDALAEDILRFGMQPSGNPGHPPTGALLKAETVHVERLTRERIHEL
AHDAEHARVLEAIGPVSFIAVPLIARGQVLGVLSFIHAHSGRHYSTSDLAFAKELAHRAALSLENARLYAEAREAIRLRD
EFMSIASHELKTPLTPLSLKLQALSRELARHPGPVPRNLVESYVAVGARQVQKLAELVGDLLDVSRISAGRLSLELEELE
LGSLVRDVVTRYEPQAARTGSPLQLEAGDFDIVGRWDRLRLEQVITNLVDNAVKYGNGRPIHVRLEPHDGGARLTVRDEG
IGIEPQHLPRLFGRFERAVSERNYGGLGLGLYITRTLVEAMGGRVHVESRLGRGSTFTVELPSHLGAEQARQAP
>Mature_714_residues
MRGSSPAVCMQPAGSPPLTMHARPERHHPLWASRAGRYGVALLAFVAAWLIQAGTMSFIPATPFLFFFGAVMVSGWWGGW
GPALATTLLSVVVVDFYFLEPLLNLMPGTGGAVSLAVFVVLALLMTKLNVMLRKANAERARLLERERAARSEAEAGQARL
HALFRDAPAAIILMHGPRHIYSFSNTMNNTLMGTDTLVGQEASKALPWAESRGFITLLDEVYRTGVPFTGNAVPFPRKPP
HDEIQETYLNIVYQPTRNEQGEVDGIAGFGFDVTDLVRARQRAEALTHELQLAEARDWLLAESGAVLASSLDDETTLRNM
AKLVVPTFADWCLVDVAEPDGTFRRLEAAHFRLEDDALAEDILRFGMQPSGNPGHPPTGALLKAETVHVERLTRERIHEL
AHDAEHARVLEAIGPVSFIAVPLIARGQVLGVLSFIHAHSGRHYSTSDLAFAKELAHRAALSLENARLYAEAREAIRLRD
EFMSIASHELKTPLTPLSLKLQALSRELARHPGPVPRNLVESYVAVGARQVQKLAELVGDLLDVSRISAGRLSLELEELE
LGSLVRDVVTRYEPQAARTGSPLQLEAGDFDIVGRWDRLRLEQVITNLVDNAVKYGNGRPIHVRLEPHDGGARLTVRDEG
IGIEPQHLPRLFGRFERAVSERNYGGLGLGLYITRTLVEAMGGRVHVESRLGRGSTFTVELPSHLGAEQARQAP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=264, Percent_Identity=34.8484848484849, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI145693157, Length=277, Percent_Identity=28.5198555956679, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1786600, Length=276, Percent_Identity=30.7971014492754, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=32.9317269076305, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=25.7936507936508, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=32.7510917030568, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=30.1310043668122, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI48994928, Length=275, Percent_Identity=27.6363636363636, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=275, Percent_Identity=29.4545454545455, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=28.8288288288288, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=30, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=26.9565217391304, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=29.004329004329, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=25.5506607929515, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78417; Mature: 78417

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGSSPAVCMQPAGSPPLTMHARPERHHPLWASRAGRYGVALLAFVAAWLIQAGTMSFIP
CCCCCCCEEECCCCCCCEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHCC
ATPFLFFFGAVMVSGWWGGWGPALATTLLSVVVVDFYFLEPLLNLMPGTGGAVSLAVFVV
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LALLMTKLNVMLRKANAERARLLERERAARSEAEAGQARLHALFRDAPAAIILMHGPRHI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHH
YSFSNTMNNTLMGTDTLVGQEASKALPWAESRGFITLLDEVYRTGVPFTGNAVPFPRKPP
HHHHHHHCCCCCCCHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
HDEIQETYLNIVYQPTRNEQGEVDGIAGFGFDVTDLVRARQRAEALTHELQLAEARDWLL
HHHHHHHHHHEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AESGAVLASSLDDETTLRNMAKLVVPTFADWCLVDVAEPDGTFRRLEAAHFRLEDDALAE
HCCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHH
DILRFGMQPSGNPGHPPTGALLKAETVHVERLTRERIHELAHDAEHARVLEAIGPVSFIA
HHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VPLIARGQVLGVLSFIHAHSGRHYSTSDLAFAKELAHRAALSLENARLYAEAREAIRLRD
HHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFMSIASHELKTPLTPLSLKLQALSRELARHPGPVPRNLVESYVAVGARQVQKLAELVGD
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLDVSRISAGRLSLELEELELGSLVRDVVTRYEPQAARTGSPLQLEAGDFDIVGRWDRLR
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHCCCCCEEEECCCEEEECCHHHHH
LEQVITNLVDNAVKYGNGRPIHVRLEPHDGGARLTVRDEGIGIEPQHLPRLFGRFERAVS
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
ERNYGGLGLGLYITRTLVEAMGGRVHVESRLGRGSTFTVELPSHLGAEQARQAP
HCCCCCCCHHHHHHHHHHHHHCCEEEEHHHCCCCCEEEEECCHHCCHHHHCCCC
>Mature Secondary Structure
MRGSSPAVCMQPAGSPPLTMHARPERHHPLWASRAGRYGVALLAFVAAWLIQAGTMSFIP
CCCCCCCEEECCCCCCCEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHCC
ATPFLFFFGAVMVSGWWGGWGPALATTLLSVVVVDFYFLEPLLNLMPGTGGAVSLAVFVV
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LALLMTKLNVMLRKANAERARLLERERAARSEAEAGQARLHALFRDAPAAIILMHGPRHI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHH
YSFSNTMNNTLMGTDTLVGQEASKALPWAESRGFITLLDEVYRTGVPFTGNAVPFPRKPP
HHHHHHHCCCCCCCHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
HDEIQETYLNIVYQPTRNEQGEVDGIAGFGFDVTDLVRARQRAEALTHELQLAEARDWLL
HHHHHHHHHHEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AESGAVLASSLDDETTLRNMAKLVVPTFADWCLVDVAEPDGTFRRLEAAHFRLEDDALAE
HCCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHH
DILRFGMQPSGNPGHPPTGALLKAETVHVERLTRERIHELAHDAEHARVLEAIGPVSFIA
HHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VPLIARGQVLGVLSFIHAHSGRHYSTSDLAFAKELAHRAALSLENARLYAEAREAIRLRD
HHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFMSIASHELKTPLTPLSLKLQALSRELARHPGPVPRNLVESYVAVGARQVQKLAELVGD
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLDVSRISAGRLSLELEELELGSLVRDVVTRYEPQAARTGSPLQLEAGDFDIVGRWDRLR
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHCCCCCEEEECCCEEEECCHHHHH
LEQVITNLVDNAVKYGNGRPIHVRLEPHDGGARLTVRDEGIGIEPQHLPRLFGRFERAVS
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
ERNYGGLGLGLYITRTLVEAMGGRVHVESRLGRGSTFTVELPSHLGAEQARQAP
HCCCCCCCHHHHHHHHHHHHHCCEEEEHHHCCCCCEEEEECCHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]