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The map label for this gene is coaD [H]

Identifier: 108563863

GI number: 108563863

Start: 1496297

End: 1496770

Strand: Direct

Name: coaD [H]

Synonym: HPAG1_1438

Alternate gene names: 108563863

Gene position: 1496297-1496770 (Clockwise)

Preceding gene: 108563862

Following gene: 108563864

Centisome position: 93.73

GC content: 41.56

Gene sequence:

>474_bases
ATGCAAAAAATCGGCATTTATCCGGGCACTTTTGATCCGGTCACTAACGGGCATATAGACATCATCCATCGATCCAGCGA
ATTGTTTGAAAAGCTCATTGTCGCTGTGGCGCATTCAAGTGCTAAAAACCCCATGTTTAGTTTGAAAGAGCGCTTAAAAA
TGATGCAACTGGCCACTAAAAGTTTTAAAAATGTAGAATGCGTGGCGTTTGAAGGGCTGTTAGCCAATCTGGCTAAAGAA
TACCATTGTAAGGTGCTAGTTAGGGGCTTAAGGGTGGTGAGCGATTTTGAATACGAATTGCAAATGGGCTATGCGAACAA
ATCCTTAAACCACGAATTAGAAACCTTGTATTTCATGCCCACTTTGCAAAACGCTTTCATCAGCTCTTCTATCGTGCGAT
CCATTATCGCGCATAAGGGTGATGCGAGCCATTTAGTGCCTAAAGAAATTTATCCTTTGATTTCAAAGGCTTAA

Upstream 100 bases:

>100_bases
AGAGCAAGACTTTAGAGGCGATGCAAGATTTTTTAGTGGGGAAGTGGTTTGACAGCTTAGGGATAGAAAATGACTTATAC
CCACGATGGGGAATGAACTG

Downstream 100 bases:

>100_bases
AATGTATGTGGTGTTAGAAGGCGTTGATGGCGTGGGCAAAAGCACTCAAGTAGGATTGTTAAAAGACCGGTTTAAAAACG
CCCTTTTTACCAAAGAGCCA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLKMMQLATKSFKNVECVAFEGLLANLAKE
YHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA

Sequences:

>Translated_157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLKMMQLATKSFKNVECVAFEGLLANLAKE
YHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA
>Mature_157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLKMMQLATKSFKNVECVAFEGLLANLAKE
YHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=151, Percent_Identity=49.6688741721854, Blast_Score=178, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17699; Mature: 17699

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLKMMQLATK
CCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHHEECH
TLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLKMMQLATK
CCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHHEECH
TLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA