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The map label for this gene is yrbH [C]

Identifier: 108563779

GI number: 108563779

Start: 1405155

End: 1406144

Strand: Reverse

Name: yrbH [C]

Synonym: HPAG1_1354

Alternate gene names: 108563779

Gene position: 1406144-1405155 (Counterclockwise)

Preceding gene: 108563780

Following gene: 108563778

Centisome position: 88.08

GC content: 42.73

Gene sequence:

>990_bases
ATGCCCATGCTTTTTGATTGTAACGCTACCGCTATACAAGTCTTAAAAGATGAAGCGAGCGCGCTTTTAGAAAGCGTTAA
ACAATTCCAAGAACCTAATGATTTAGAAGCGATTGTCAAGCTCATTTTAAAAAGCCAAGAAAAAGGGGGTAAGCTTGTGA
TAGTGGGCGTGGGCAAGAGCGCTTTAGTGGCGCAAAAAATCACTGCTTCCATGCTAAGCACCGGTAACAGGAGCGCGTTT
TTACACCCAACAGAAGCCATGCATGGGGATTTGGGCATGGTGGAAAAAAACGATGTGATCTTAATGATTAGTTACGGGGG
CGAGTCTTTAGAATTATTGAATCTGGTGAGCCATTTAAAACGCTTGAGTCATAAAATCATCACTTTCACTAAAAGCCCTA
ATAGCTCGCTCTCCAAACTCGGCGATTATTATTTGAGCTTGAAAATTCAAAAAGAAGCTTGCCCGATCAACACCGCTCCA
ACGACTTCTACCACCCTAACTCTAGCGTTAGGCGATGTTTTAATGGCATGCTTGATGCGAGCGAAAAACTTTAGCCAAGA
AGATTTTGCCTCCTTTCATCCGGGCGGGCTTTTAGGCAAAAAACTTTTTGTCAAGGTTAAAGATTTACTGCAAACCACGA
ACCTCCCCCTAATCGCTCCTAATACAAGTTTTAAAGACGCGCTCATAGAAATGAGTGAAAAACGCTTAGGCAGCGCGATT
TTAGTCAATGAGGCTAACGAGCTTGTGGGGGTGTTAAGCGATGGCGATGTCCGTAGGGCGTTATTAAAAGGGGTGAGTTT
AAAGAGCGAAGTGAGGCATTTTGCCACTTTAAAGCCTAAAAGCTTTAAGAATTTAGACGCTCTTCTTTTAGAGGCGTTAG
AATTTTTAGAGCGCCATAAGATCCAGCTTTTGGTGTGCGTGGATGATTGTAATAAGGTTTTAGGGGTCTTGCACTTGCAC
CAACTTTTAGAATTAGGGCTTAAAGCATGA

Upstream 100 bases:

>100_bases
GAAATTTTGAATAACCCTAAAAAATTAGAAGATCACACTCGTAATTTCATCAGAAAGGCGCTCTTTAAAAAGTTTAGAAA
ATACCCGGCTATCGTTTGTC

Downstream 100 bases:

>100_bases
AAGCGAGCATTTATGATTTCACTTTAGATGAATTGAGTCAGCTTTTAAAACCAAGTTTTAGGGCTAAACAGCTTTATTTG
TGGCTCTATGCGAAGTATAA

Product: polysialic acid capsule expression protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPMLFDCNATAIQVLKDEASALLESVKQFQEPNDLEAIVKLILKSQEKGGKLVIVGVGKSALVAQKITASMLSTGNRSAF
LHPTEAMHGDLGMVEKNDVILMISYGGESLELLNLVSHLKRLSHKIITFTKSPNSSLSKLGDYYLSLKIQKEACPINTAP
TTSTTLTLALGDVLMACLMRAKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPNTSFKDALIEMSEKRLGSAI
LVNEANELVGVLSDGDVRRALLKGVSLKSEVRHFATLKPKSFKNLDALLLEALEFLERHKIQLLVCVDDCNKVLGVLHLH
QLLELGLKA

Sequences:

>Translated_329_residues
MPMLFDCNATAIQVLKDEASALLESVKQFQEPNDLEAIVKLILKSQEKGGKLVIVGVGKSALVAQKITASMLSTGNRSAF
LHPTEAMHGDLGMVEKNDVILMISYGGESLELLNLVSHLKRLSHKIITFTKSPNSSLSKLGDYYLSLKIQKEACPINTAP
TTSTTLTLALGDVLMACLMRAKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPNTSFKDALIEMSEKRLGSAI
LVNEANELVGVLSDGDVRRALLKGVSLKSEVRHFATLKPKSFKNLDALLLEALEFLERHKIQLLVCVDDCNKVLGVLHLH
QLLELGLKA
>Mature_328_residues
PMLFDCNATAIQVLKDEASALLESVKQFQEPNDLEAIVKLILKSQEKGGKLVIVGVGKSALVAQKITASMLSTGNRSAFL
HPTEAMHGDLGMVEKNDVILMISYGGESLELLNLVSHLKRLSHKIITFTKSPNSSLSKLGDYYLSLKIQKEACPINTAPT
TSTTLTLALGDVLMACLMRAKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPNTSFKDALIEMSEKRLGSAIL
VNEANELVGVLSDGDVRRALLKGVSLKSEVRHFATLKPKSFKNLDALLLEALEFLERHKIQLLVCVDDCNKVLGVLHLHQ
LLELGLKA

Specific function: Unknown

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789588, Length=326, Percent_Identity=38.6503067484663, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI87082151, Length=279, Percent_Identity=36.9175627240143, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR004800
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00571 CBS; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 35912; Mature: 35781

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMLFDCNATAIQVLKDEASALLESVKQFQEPNDLEAIVKLILKSQEKGGKLVIVGVGKS
CCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCH
ALVAQKITASMLSTGNRSAFLHPTEAMHGDLGMVEKNDVILMISYGGESLELLNLVSHLK
HHHHHHHHHHHHCCCCCCEEECCHHHHCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
RLSHKIITFTKSPNSSLSKLGDYYLSLKIQKEACPINTAPTTSTTLTLALGDVLMACLMR
HHHHHEEEEECCCCHHHHHHCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPNTSFKDALIEMSEKRLGSAI
HCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCEE
LVNEANELVGVLSDGDVRRALLKGVSLKSEVRHFATLKPKSFKNLDALLLEALEFLERHK
EEECHHHHEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
IQLLVCVDDCNKVLGVLHLHQLLELGLKA
EEEEEEEHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PMLFDCNATAIQVLKDEASALLESVKQFQEPNDLEAIVKLILKSQEKGGKLVIVGVGKS
CEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCH
ALVAQKITASMLSTGNRSAFLHPTEAMHGDLGMVEKNDVILMISYGGESLELLNLVSHLK
HHHHHHHHHHHHCCCCCCEEECCHHHHCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
RLSHKIITFTKSPNSSLSKLGDYYLSLKIQKEACPINTAPTTSTTLTLALGDVLMACLMR
HHHHHEEEEECCCCHHHHHHCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPNTSFKDALIEMSEKRLGSAI
HCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCEE
LVNEANELVGVLSDGDVRRALLKGVSLKSEVRHFATLKPKSFKNLDALLLEALEFLERHK
EEECHHHHEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
IQLLVCVDDCNKVLGVLHLHQLLELGLKA
EEEEEEEHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]