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The map label for this gene is silB [H]

Identifier: 108563698

GI number: 108563698

Start: 1319577

End: 1320593

Strand: Direct

Name: silB [H]

Synonym: HPAG1_1273

Alternate gene names: 108563698

Gene position: 1319577-1320593 (Clockwise)

Preceding gene: 108563697

Following gene: 108563699

Centisome position: 82.66

GC content: 38.15

Gene sequence:

>1017_bases
ATGAAACGGATTTTATTTTTAGCCTTGATTTTATTTTTTAGCCCCTTATTCGCTAACGCTCAAAAAACTCAAGAAATTAA
AGAAACTAAAGAAGCTAAAAGCCAAACCCGTTTTAATATTTCCACCACTAAAGTCATAGAAAAAGAATTTTCTCAAAGCC
GGCGCTATTACGCGCTCCTAGAGCCTAATGAAGCGCTGATTTTTTCTCAAACCCTGCGTTTTGATGGCTATGTGGAAAAG
CTTTATGCGAATAAAACCTATACCCCCATTAAAAAGGGCGATCGGTTATTGAGCGTGTATTCCCCTGAATTAGTGAGCGC
TCAAAGCGAATTGCTATCATCATTGAAATTCAACCAGCAAGTGGGAGCGATTAAAGAAAAATTAAAACTATTGGGGCTAG
AAAACTTTAGCATTGAAAAAACCATCAGCGCTCATAAAGTCCAAAATGAAATGACTATTTACTCTCGTTTCAACGGCGTT
ATTTTTAAAAAAAGCCCGGATCTCAATGAGGGGAGCTTCATTAAAAAAGGGCAAGAGTTGTTTCAAATCATAGATTTAAG
CCAATTGTGGGCGCTGGTTAAAGTCAATCAAGAGGATTTAGAATTTTTAAAAAACACGCATAAAGCGATCTTGTTCGTAG
AAGGGATTAAAGGCGAGCAAGAAATCACGCTTGAAAACATCAACCCCATCATAAATGCGCAAGATAAAATGCTAGAAGCG
CGCTTCAATGTGCCTAATGTCAAACAGCTTTATTACCCTAACATGTTCGCTCAAGTAGAAATCTTTCAAAAACCACAAAA
AATGAAGATTTTGCCTAAAGAAGCGGTTTTGATTAAAGGGGGGAAAGCTATCGTGTTCAAAAAAGACGATTTTGGCTTAA
GCCCGTTAGAAATTAAAGCCGTCCGCTTGAGCGATGGGAGTTATGAAATTTTAGAGGGTTTAAAAGCGGGCGAAGAAGTG
GCTAATAACGCTTTATTCGTGCTAGACGCTGACGCTCAAAACAATGGGGATTATTGA

Upstream 100 bases:

>100_bases
ACGCTTTTAACGACAAAATCACTATCCAAATCACCCAGCTTGAAACCTTAAGCGCTCTAAATAGTGCTTATTTGTCTTTA
CAAAACCTTAAAGGATTAGA

Downstream 100 bases:

>100_bases
ATGATAGAAAAAATCATTGATTTAAGCGTTAAAAACAAACTCCTTACCACTTTAGTAACCCTACTCATTTTTTTAGCCTC
TTTGTGGGCGATAAAAAGCG

Product: cation efflux system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKRILFLALILFFSPLFANAQKTQEIKETKEAKSQTRFNISTTKVIEKEFSQSRRYYALLEPNEALIFSQTLRFDGYVEK
LYANKTYTPIKKGDRLLSVYSPELVSAQSELLSSLKFNQQVGAIKEKLKLLGLENFSIEKTISAHKVQNEMTIYSRFNGV
IFKKSPDLNEGSFIKKGQELFQIIDLSQLWALVKVNQEDLEFLKNTHKAILFVEGIKGEQEITLENINPIINAQDKMLEA
RFNVPNVKQLYYPNMFAQVEIFQKPQKMKILPKEAVLIKGGKAIVFKKDDFGLSPLEIKAVRLSDGSYEILEGLKAGEEV
ANNALFVLDADAQNNGDY

Sequences:

>Translated_338_residues
MKRILFLALILFFSPLFANAQKTQEIKETKEAKSQTRFNISTTKVIEKEFSQSRRYYALLEPNEALIFSQTLRFDGYVEK
LYANKTYTPIKKGDRLLSVYSPELVSAQSELLSSLKFNQQVGAIKEKLKLLGLENFSIEKTISAHKVQNEMTIYSRFNGV
IFKKSPDLNEGSFIKKGQELFQIIDLSQLWALVKVNQEDLEFLKNTHKAILFVEGIKGEQEITLENINPIINAQDKMLEA
RFNVPNVKQLYYPNMFAQVEIFQKPQKMKILPKEAVLIKGGKAIVFKKDDFGLSPLEIKAVRLSDGSYEILEGLKAGEEV
ANNALFVLDADAQNNGDY
>Mature_338_residues
MKRILFLALILFFSPLFANAQKTQEIKETKEAKSQTRFNISTTKVIEKEFSQSRRYYALLEPNEALIFSQTLRFDGYVEK
LYANKTYTPIKKGDRLLSVYSPELVSAQSELLSSLKFNQQVGAIKEKLKLLGLENFSIEKTISAHKVQNEMTIYSRFNGV
IFKKSPDLNEGSFIKKGQELFQIIDLSQLWALVKVNQEDLEFLKNTHKAILFVEGIKGEQEITLENINPIINAQDKMLEA
RFNVPNVKQLYYPNMFAQVEIFQKPQKMKILPKEAVLIKGGKAIVFKKDDFGLSPLEIKAVRLSDGSYEILEGLKAGEEV
ANNALFVLDADAQNNGDY

Specific function: Component of the sil cation efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=270, Percent_Identity=25.5555555555556, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38553; Mature: 38553

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILFLALILFFSPLFANAQKTQEIKETKEAKSQTRFNISTTKVIEKEFSQSRRYYALL
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCEEEEE
EPNEALIFSQTLRFDGYVEKLYANKTYTPIKKGDRLLSVYSPELVSAQSELLSSLKFNQQ
CCCCEEEEEEHHHHHHHHHHHHCCCCCCCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
VGAIKEKLKLLGLENFSIEKTISAHKVQNEMTIYSRFNGVIFKKSPDLNEGSFIKKGQEL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCHHHHHHHHH
FQIIDLSQLWALVKVNQEDLEFLKNTHKAILFVEGIKGEQEITLENINPIINAQDKMLEA
HHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHH
RFNVPNVKQLYYPNMFAQVEIFQKPQKMKILPKEAVLIKGGKAIVFKKDDFGLSPLEIKA
HCCCCCCHHHHCCCHHEEEHHHCCCCCCEECCCCEEEEECCEEEEEECCCCCCCCEEEEE
VRLSDGSYEILEGLKAGEEVANNALFVLDADAQNNGDY
EEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MKRILFLALILFFSPLFANAQKTQEIKETKEAKSQTRFNISTTKVIEKEFSQSRRYYALL
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCEEEEE
EPNEALIFSQTLRFDGYVEKLYANKTYTPIKKGDRLLSVYSPELVSAQSELLSSLKFNQQ
CCCCEEEEEEHHHHHHHHHHHHCCCCCCCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
VGAIKEKLKLLGLENFSIEKTISAHKVQNEMTIYSRFNGVIFKKSPDLNEGSFIKKGQEL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCHHHHHHHHH
FQIIDLSQLWALVKVNQEDLEFLKNTHKAILFVEGIKGEQEITLENINPIINAQDKMLEA
HHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHH
RFNVPNVKQLYYPNMFAQVEIFQKPQKMKILPKEAVLIKGGKAIVFKKDDFGLSPLEIKA
HCCCCCCHHHHCCCHHEEEHHHCCCCCCEECCCCEEEEECCEEEEEECCCCCCCCEEEEE
VRLSDGSYEILEGLKAGEEVANNALFVLDADAQNNGDY
EEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]