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The map label for this gene is nuoC [H]

Identifier: 108563631

GI number: 108563631

Start: 1267273

End: 1268073

Strand: Direct

Name: nuoC [H]

Synonym: HPAG1_1206

Alternate gene names: 108563631

Gene position: 1267273-1268073 (Clockwise)

Preceding gene: 108563630

Following gene: 108563632

Centisome position: 79.38

GC content: 41.95

Gene sequence:

>801_bases
GTGATGGTAAGAAAACAATCCCCCTATGAAGATGTGCAAAAACAATCGCGCCAGCATGACCCCTATAAAATCATAGAACC
CACCCCTAAAAAATATTTAGAGGGCAGCGCTTATGAGGTCATTTATAACCACCTTTCTTACAAGCATGAGGTTTTAGACA
AGTATATAGAAACTAACACGGCGGTGTTTTGGGTCAAAAAAGACGATATTTTTTCTGTCGCTACGACTTTAAGGCATTTG
GGTTATGAGTGTTTGAGCGAAATGAGCGCGATAGATTTGTGCGCTAAAAAAGGGCATTTTGAATTGTTTTATCAATTTGT
GGGTTTTAGCGATAGTTGCAAGAACCGCCGTAGGGTGCGCGTGAAATGCATTCTGTTGCCTAATGAAAGCGTGGATTCTT
TGAGTTTTTTATACCGCTCGGCTAATTGGAGCGAGAGGGAAGCGTATGATTTGCTTGGCATTGTGTTTGACAAACACCCC
TATTTGAAGCGCCTTATCATGCCGCATGATTGGGTAGGCCACCCTTTGTTGCGTTCTTACCCGCTCAAAGGCGATGAATT
CGCCCAATGGTATGAAGTGGATAAAATTTTTGGTAAAGAATACCGAGAAGTGGTGGGTAAAGAGCAACGAGACAGCGCGA
GAGTGGATGAAAAAGACACTTTCAATTTCGCTAAAATTGGCTATGAGCAGGGCAAGGGCGAAGAATTGAAAGAAACAGAA
GAAAAGCATGCGTTTAAGAAAATCCCTTTTGTCAAAGATTTGCACAAAATCGCCCCCACTATCTTAAAAAAGAGGCTATA
A

Upstream 100 bases:

>100_bases
GCGCACCGCGCCCAGAGACTTTACAATACGCTCTTATGGTTTTACAAGATAAAATCAGACGCTCTAAAGCGATCAAACAA
GACGCTCCTAAAAGGTTAGT

Downstream 100 bases:

>100_bases
AATGGCTCAAAATTTCACGAAACTCAACCCCCAGTTTGAAAACATCATTTTTGAACATGACGACAACCAAATGATTTTAA
ACTTTGGTCCCCAACACCCC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MMVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEVLDKYIETNTAVFWVKKDDIFSVATTLRHL
GYECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRVKCILLPNESVDSLSFLYRSANWSEREAYDLLGIVFDKHP
YLKRLIMPHDWVGHPLLRSYPLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETE
EKHAFKKIPFVKDLHKIAPTILKKRL

Sequences:

>Translated_266_residues
MMVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEVLDKYIETNTAVFWVKKDDIFSVATTLRHL
GYECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRVKCILLPNESVDSLSFLYRSANWSEREAYDLLGIVFDKHP
YLKRLIMPHDWVGHPLLRSYPLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETE
EKHAFKKIPFVKDLHKIAPTILKKRL
>Mature_266_residues
MMVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEVLDKYIETNTAVFWVKKDDIFSVATTLRHL
GYECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRVKCILLPNESVDSLSFLYRSANWSEREAYDLLGIVFDKHP
YLKRLIMPHDWVGHPLLRSYPLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETE
EKHAFKKIPFVKDLHKIAPTILKKRL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=147, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI145693162, Length=182, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990788, Length=103, Percent_Identity=31.0679611650485, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32563621, Length=103, Percent_Identity=31.0679611650485, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24656494, Length=103, Percent_Identity=32.0388349514563, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 31475; Mature: 31475

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEVLDKYIETNT
CCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
AVFWVKKDDIFSVATTLRHLGYECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVR
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCEEE
VKCILLPNESVDSLSFLYRSANWSEREAYDLLGIVFDKHPYLKRLIMPHDWVGHPLLRSY
EEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHC
PLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCCCCCHHHHHH
EKHAFKKIPFVKDLHKIAPTILKKRL
HHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEVLDKYIETNT
CCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
AVFWVKKDDIFSVATTLRHLGYECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVR
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCEEE
VKCILLPNESVDSLSFLYRSANWSEREAYDLLGIVFDKHPYLKRLIMPHDWVGHPLLRSY
EEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHC
PLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCCCCCHHHHHH
EKHAFKKIPFVKDLHKIAPTILKKRL
HHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA