| Definition | Helicobacter pylori HPAG1 chromosome, complete genome. |
|---|---|
| Accession | NC_008086 |
| Length | 1,596,366 |
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The map label for this gene is speA [H]
Identifier: 108563397
GI number: 108563397
Start: 1021469
End: 1023316
Strand: Reverse
Name: speA [H]
Synonym: HPAG1_0972
Alternate gene names: 108563397
Gene position: 1023316-1021469 (Counterclockwise)
Preceding gene: 108563398
Following gene: 108563391
Centisome position: 64.1
GC content: 40.21
Gene sequence:
>1848_bases ATGCAAGAAGTCCATGATTATGGGATTAAATTTTGGAGCAATAACGAATTTAAGATAGAAAAAGGCTTGGTTAAAGTTTG CCATGGCAAAAACCCCTCGCTTTTAGAAATCGTTCAAAGCGTGCGCGATAAGGGCTATAGAGGGCCTTTGTTAGTGCGAT TCCCCCATTTGGTGCAAAAACAAATCAAAAGCCTGTTTGATGCGTTTTCTTCAGCGATTAAAGAGTATCAATACAGCGGG GCTTTTAAGGCGGTTTTCCCTTTAAAGGTCAATCAAATGCCCTCGTTTGTTTTCCCTTTAGTGCAAGGGGCTAAGGGTTT GGATTACGGGTTAGAAGCTGGGAGCAAGTCTGAGCTCATCATTGCGATGAGTTACACTAACCCTAAAGCCCCTATCACCG TGAATGGTTTTAAAGACAAAGAAATGATTGAGCTTGGCTTTATCGCTAAAAGCATGCAGCATGAAATCACTTTAACGATT GAGGGTTTGAATGAGTTAAAAACCATTATCGCTGTGGCTAAACAAAACGATTTTGTAGCATGCCCTAAAATTGGCATTCG CATCCGTTTGCACAGCGCTGGCACTGGCGTTTGGGCAAAGAGTGGGGGAATCAATTCTAAATTTGGTCTTAGCAGCACTG AAGTTTTAGAAGCGATACGCCTTTTAGAAGAAAACGACTTACTAGAGCATTTCCACATGATACATTTCCACATAGGCTCT CAAATCAGCGATATTTCGCCTTTAAAAAAGGCTTTAAGAGAAGCGGGAAACTTGTATGCAGAATTGCGTAAAATGGGCGC TAAAAATCTTAATAGCGTGAATATTGGAGGGGGGTTAGCCGTAGAATACACCCAGCACAAGCACCACCAAGATAAAAACT ACACTTTAGAAGAATTCAGCGCTGATGTGGTGTTTTTATTGAGGGAAATTGTGAAAAACAAGCAGGAAATAGAGCCGGAT ATTTTCATTGAATCAGGCCGTTATATTTCCGCTAACCATGCCGTTTTAGTGGCCCCGGTGTTAGAATTGTTTTCGCATGA ATACAATGAAAAATCCCTAAAAATCAAAGAAAATAATAACCCCCCTTTGATTGATGAAATGCTAGACTTGCTCGCTAATA TCAATGAAAAAAACGCCATTGAATACTTGCATGATAGTTTTGATCACACCGAGTCGCTGTTCACGCTTTTTGATTTGGGC TATATTGATTTGATTGACAGAAGCAACACTGAAGTTTTAGCCCATTTGATCGTCAAAAAAGCGGTGCAATTGCTTTATGT TAAGGATCATAACGATATTTTACGCATTCAAGAGCAGGTCCAAGAGCGCTATTTATTGAATTGCTCGTTTTTCCAAAGCT TGCCGGATTATTGGGGCTTGAGACAGAATTTCCCGGTCATGCCTTTGAATAAATTAGATGAAAAGCCCACCAGGAGCGCG AGCTTGTGGGATATTACTTGCGATAGCGATGGGGAAATCGCTTTTGATTCCACGAAGCCCTTGTTTTTGCATGATATAGA CATAGATGAAGAAGAATACTTTTTAGCGTTCTTTTTAGTGGGAGCGTATCAAGAAGTTTTAGGCATGAAACACAATTTAT TCACGCACCCTACGGAATTTAGCGTGGTTTTTGATGAAAAAGGCGATTATGAAGTGGAAGATATTTGCGAAGCCCAAACG ATTTTAGATGTGCTAGACGATTTAGACTATGACACTAAAGAAATTGAGCGCCTTTTAAAACAAAAAATTGAAGACAACAA CCAACTGGACATGGAAGAAAAAAAAGAAATCATGGGGCGCTTGTATGTCATGCTGAGCGAAAACGGGTATTTGCGCACGA TTTCTTAA
Upstream 100 bases:
>100_bases ATTCAGTCATTCAAATTGAAAAAGTTTATGAAGAAGCGATCAGAGATTTTAAAAATAACCCCCATCTTTTTAAAACCTTA TCGTAGCAAAAGGATAAAAA
Downstream 100 bases:
>100_bases AAGAACGCTATAAATGGATTTAAACGGCTTTAATCGCTATAAATCAATAGAAGAATGAGAAAAAGAAAAGAGATTAAAAA AAGAGAGCCACCCACAAGGG
Product: arginine decarboxylase
Products: NA
Alternate protein names: ADC [H]
Number of amino acids: Translated: 615; Mature: 615
Protein sequence:
>615_residues MQEVHDYGIKFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQKQIKSLFDAFSSAIKEYQYSG AFKAVFPLKVNQMPSFVFPLVQGAKGLDYGLEAGSKSELIIAMSYTNPKAPITVNGFKDKEMIELGFIAKSMQHEITLTI EGLNELKTIIAVAKQNDFVACPKIGIRIRLHSAGTGVWAKSGGINSKFGLSSTEVLEAIRLLEENDLLEHFHMIHFHIGS QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFSADVVFLLREIVKNKQEIEPD IFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKENNNPPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLG YIDLIDRSNTEVLAHLIVKKAVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA SLWDITCDSDGEIAFDSTKPLFLHDIDIDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEFSVVFDEKGDYEVEDICEAQT ILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGRLYVMLSENGYLRTIS
Sequences:
>Translated_615_residues MQEVHDYGIKFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQKQIKSLFDAFSSAIKEYQYSG AFKAVFPLKVNQMPSFVFPLVQGAKGLDYGLEAGSKSELIIAMSYTNPKAPITVNGFKDKEMIELGFIAKSMQHEITLTI EGLNELKTIIAVAKQNDFVACPKIGIRIRLHSAGTGVWAKSGGINSKFGLSSTEVLEAIRLLEENDLLEHFHMIHFHIGS QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFSADVVFLLREIVKNKQEIEPD IFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKENNNPPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLG YIDLIDRSNTEVLAHLIVKKAVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA SLWDITCDSDGEIAFDSTKPLFLHDIDIDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEFSVVFDEKGDYEVEDICEAQT ILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGRLYVMLSENGYLRTIS >Mature_615_residues MQEVHDYGIKFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQKQIKSLFDAFSSAIKEYQYSG AFKAVFPLKVNQMPSFVFPLVQGAKGLDYGLEAGSKSELIIAMSYTNPKAPITVNGFKDKEMIELGFIAKSMQHEITLTI EGLNELKTIIAVAKQNDFVACPKIGIRIRLHSAGTGVWAKSGGINSKFGLSSTEVLEAIRLLEENDLLEHFHMIHFHIGS QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFSADVVFLLREIVKNKQEIEPD IFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKENNNPPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLG YIDLIDRSNTEVLAHLIVKKAVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA SLWDITCDSDGEIAFDSTKPLFLHDIDIDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEFSVVFDEKGDYEVEDICEAQT ILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGRLYVMLSENGYLRTIS
Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]
COG id: COG1166
COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)
Gene ontology:
Cell location: Periplasmic Protein [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]
Homologues:
Organism=Escherichia coli, GI1789307, Length=615, Percent_Identity=32.6829268292683, Blast_Score=333, Evalue=2e-92,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009006 - InterPro: IPR002985 - InterPro: IPR022643 - InterPro: IPR022644 - InterPro: IPR022653 - InterPro: IPR000183 [H]
Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]
EC number: =4.1.1.19 [H]
Molecular weight: Translated: 70255; Mature: 70255
Theoretical pI: Translated: 5.02; Mature: 5.02
Prosite motif: PS00012 PHOSPHOPANTETHEINE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQEVHDYGIKFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQK CCCCHHCCCEEECCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHH QIKSLFDAFSSAIKEYQYSGAFKAVFPLKVNQMPSFVFPLVQGAKGLDYGLEAGSKSELI HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCEE IAMSYTNPKAPITVNGFKDKEMIELGFIAKSMQHEITLTIEGLNELKTIIAVAKQNDFVA EEEECCCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEE CPKIGIRIRLHSAGTGVWAKSGGINSKFGLSSTEVLEAIRLLEENDLLEHFHMIHFHIGS CCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFS CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEHHHHCCCCCCCCHHHHH ADVVFLLREIVKNKQEIEPDIFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKENNN HHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCC PPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLGYIDLIDRSNTEVLAHLIVKK CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHH AVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA HHHEEEEECCCHHHHHHHHHHHHHHCCHHHHHHCHHHCCCCCCCCCCCCHHCCCCCCCCC SLWDITCDSDGEIAFDSTKPLFLHDIDIDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEF EEEEEEECCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCE SVVFDEKGDYEVEDICEAQTILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGR EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH LYVMLSENGYLRTIS EEEEEECCCEEEECC >Mature Secondary Structure MQEVHDYGIKFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQK CCCCHHCCCEEECCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHH QIKSLFDAFSSAIKEYQYSGAFKAVFPLKVNQMPSFVFPLVQGAKGLDYGLEAGSKSELI HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCEE IAMSYTNPKAPITVNGFKDKEMIELGFIAKSMQHEITLTIEGLNELKTIIAVAKQNDFVA EEEECCCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEE CPKIGIRIRLHSAGTGVWAKSGGINSKFGLSSTEVLEAIRLLEENDLLEHFHMIHFHIGS CCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFS CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEHHHHCCCCCCCCHHHHH ADVVFLLREIVKNKQEIEPDIFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKENNN HHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCC PPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLGYIDLIDRSNTEVLAHLIVKK CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHH AVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA HHHEEEEECCCHHHHHHHHHHHHHHCCHHHHHHCHHHCCCCCCCCCCCCHHCCCCCCCCC SLWDITCDSDGEIAFDSTKPLFLHDIDIDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEF EEEEEEECCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCE SVVFDEKGDYEVEDICEAQTILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGR EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH LYVMLSENGYLRTIS EEEEEECCCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10567266 [H]