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The map label for this gene is rdxA

Identifier: 108563363

GI number: 108563363

Start: 979731

End: 980363

Strand: Reverse

Name: rdxA

Synonym: HPAG1_0938

Alternate gene names: 108563363

Gene position: 980363-979731 (Counterclockwise)

Preceding gene: 108563364

Following gene: 108563362

Centisome position: 61.41

GC content: 40.92

Gene sequence:

>633_bases
ATGAAATTTTTGGATCAAGAAAAAAGAAGACGATTATTAAACGAGCGCCATTCTTGCAAGATGTTTGATAGCCATTATGA
GTTTTCTAGCACAGAATTAGAAGAAATCGCTGAAATCGCCAGGCTATCGCCAAGCTCTTACAACACGCAGCCATGGCATT
TTGTGATGGTTACCAATAAGGATTTAAAAAAACAAATTGCAGCGCACAGCTACTTTAATGAAGAAATGATTAAAAGCGCT
TCAGCGTTAATGGTGGTATGCTCTTTAAGACCCAGCGAGTTGTTACCACACGGCCACTACATGCAAAACCTTTACCCGGA
GTCTTATAAGGTTAGAGTGATCCCCTCTTTTGCTCAAATGCTTGGCGTGAGATTCAACCACAGCATGCAAAGATTAGAAA
GCTATATTTTAGAGCAATGCTATATCGCTGTGGGGCAAATTTGCATGGGCGTGAGCTTAATGGGATTGGATAGTTGCATT
ATTGGAGGCTTTGATCCTTTAAAGGTGGGCGAAGTTTTAGAAGAGCGTATCAATAAGCCTAAAATCGCATGCTTGATCGC
TTTGGGTAAGAGGGTGGCAGAAGCGAGCCAAAAATCAAGAAAATCAAAAGTTGATGCGATTACTTGGTTGTGA

Upstream 100 bases:

>100_bases
AATTTGAGCATGGGGCAGATTTTAAGCTTATTTATGGTAATTGTTTCGTTAGGGATTTTATTGTATGCTACGAAAAATTC
TAAAAAATAAAGGAAAATCA

Downstream 100 bases:

>100_bases
TTAAACAAAATCAAAAACTTTTTAACTATAATCAAACCTAAATTAAAGTTTAAGGAGTGGCATTTTGTTTAAAAGAATGG
TATTAATCGCTCTTTTAGGG

Product: oxygen-insensitive NADPH nitroreductase

Products: NAD(P)(+); @TETR01.txt*5,6,7,8-Tetrahydropteridine!. [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKFLDQEKRRRLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTNKDLKKQIAAHSYFNEEMIKSA
SALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQMLGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCI
IGGFDPLKVGEVLEERINKPKIACLIALGKRVAEASQKSRKSKVDAITWL

Sequences:

>Translated_210_residues
MKFLDQEKRRRLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTNKDLKKQIAAHSYFNEEMIKSA
SALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQMLGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCI
IGGFDPLKVGEVLEERINKPKIACLIALGKRVAEASQKSRKSKVDAITWL
>Mature_210_residues
MKFLDQEKRRRLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTNKDLKKQIAAHSYFNEEMIKSA
SALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQMLGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCI
IGGFDPLKVGEVLEERINKPKIACLIALGKRVAEASQKSRKSKVDAITWL

Specific function: Reduction of a variety of nitroaromatic compounds using NADPH as source of reducing equivalents; two electrons are transferred

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitroreductase family

Homologues:

Organism=Escherichia coli, GI1786792, Length=160, Percent_Identity=29.375, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): RDXA_HELPH (Q1CSR7)

Other databases:

- EMBL:   CP000241
- RefSeq:   YP_627679.1
- ProteinModelPortal:   Q1CSR7
- SMR:   Q1CSR7
- STRING:   Q1CSR7
- GeneID:   4097956
- GenomeReviews:   CP000241_GR
- KEGG:   hpa:HPAG1_0938
- eggNOG:   COG0778
- HOGENOM:   HBG501873
- OMA:   ATAKGWA
- ProtClustDB:   CLSK496297
- BioCyc:   HPYL357544:HPAG1_0938-MONOMER
- InterPro:   IPR000415

Pfam domain/function: PF00881 Nitroreductase; SSF55469 Nitroreductase

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24095; Mature: 24095

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDQEKRRRLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTNK
CCCCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECH
DLKKQIAAHSYFNEEMIKSASALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHCCCCCEEEEECHHHHHH
LGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCIIGGFDPLKVGEVLEERINKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
KIACLIALGKRVAEASQKSRKSKVDAITWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFLDQEKRRRLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTNK
CCCCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECH
DLKKQIAAHSYFNEEMIKSASALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHCCCCCEEEEECHHHHHH
LGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCIIGGFDPLKVGEVLEERINKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
KIACLIALGKRVAEASQKSRKSKVDAITWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H; 6,7-Dihydropteridine [C]

Specific reaction: NAD(P)H + 6,7-Dihydropteridine = NAD(P)(+) + @TETR01.txt*5,6,7,8-Tetrahydropteridine!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA