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The map label for this gene is ackA [H]

Identifier: 108563309

GI number: 108563309

Start: 920149

End: 920670

Strand: Reverse

Name: ackA [H]

Synonym: HPAG1_0884

Alternate gene names: 108563309

Gene position: 920670-920149 (Counterclockwise)

Preceding gene: 108563310

Following gene: 108563308

Centisome position: 57.67

GC content: 41.19

Gene sequence:

>522_bases
TTGATGGAAATTTTAGTGTTGAATCTGGGCAGTTCGTCTATCAAGTTTAAATTGTTTGACATGAAAGAAAATAAGCCCTT
AGCGAGCGGTTTAGCTGAAAAAATCGGCGAAGAAATAGGGCAGTTGAAAATCAAATCGCATTTGCACCATAACGATCAAG
AATTAAAAGAAAAGCTTGTGATTAAAGATCATGCGAGCGGGCTTTTAATGATTCGTGAGAATTTAACGAAAATGGGCATT
ATCAAAGATTTCAACCAAATTGACGCTATAGGGCATCGTGTGGTTCAAGGGGGGGATAAATTCCATGCCCCGGTGTTAGT
GGATGAAAAAGTCATGCAAGAAATTGGCAATCTTTCTATTTTAGCCCCCTTACACAACCCGGCGAATTTAGCCGGTATTG
AGTTTGTTCAAAAAGCACACCCCCATATCCTTCAAATCGCTGTTTTTGACACCGCATTCCATGTCTATGGGGCTAACCCC
ACTAGAGGGCTTGATTATGGGCACAAGGTGTGGGGATATTGA

Upstream 100 bases:

>100_bases
AGCCCATTAACGATTTGAGTAGGGGTGCTTTAGTGGAAGATATTATCAACACCGTTTTGATTAGCGCCCTTCAAGCGCAA
GATTAATTGACTAGGAGGAA

Downstream 100 bases:

>100_bases
CCCCACTGTGGTGGAATACATTGCGCAATGCGCAAATAAGAGCTTAGAAGAAGTGATGAAAATTTTAAATCATGAAAGCG
GCTTGAAAGGCATTTGTGGG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MMEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNDQELKEKLVIKDHASGLLMIRENLTKMGI
IKDFNQIDAIGHRVVQGGDKFHAPVLVDEKVMQEIGNLSILAPLHNPANLAGIEFVQKAHPHILQIAVFDTAFHVYGANP
TRGLDYGHKVWGY

Sequences:

>Translated_173_residues
MMEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNDQELKEKLVIKDHASGLLMIRENLTKMGI
IKDFNQIDAIGHRVVQGGDKFHAPVLVDEKVMQEIGNLSILAPLHNPANLAGIEFVQKAHPHILQIAVFDTAFHVYGANP
TRGLDYGHKVWGY
>Mature_173_residues
MMEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNDQELKEKLVIKDHASGLLMIRENLTKMGI
IKDFNQIDAIGHRVVQGGDKFHAPVLVDEKVMQEIGNLSILAPLHNPANLAGIEFVQKAHPHILQIAVFDTAFHVYGANP
TRGLDYGHKVWGY

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=153, Percent_Identity=38.562091503268, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI145693184, Length=155, Percent_Identity=36.1290322580645, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 19288; Mature: 19288

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS01075 ACETATE_KINASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNDQELKEKLV
CEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IKDHASGLLMIRENLTKMGIIKDFNQIDAIGHRVVQGGDKFHAPVLVDEKVMQEIGNLSI
HHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHCCEEE
LAPLHNPANLAGIEFVQKAHPHILQIAVFDTAFHVYGANPTRGLDYGHKVWGY
EEECCCCCCHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNDQELKEKLV
CEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IKDHASGLLMIRENLTKMGIIKDFNQIDAIGHRVVQGGDKFHAPVLVDEKVMQEIGNLSI
HHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHCCEEE
LAPLHNPANLAGIEFVQKAHPHILQIAVFDTAFHVYGANPTRGLDYGHKVWGY
EEECCCCCCHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]