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The map label for this gene is 108563170

Identifier: 108563170

GI number: 108563170

Start: 781310

End: 782899

Strand: Reverse

Name: 108563170

Synonym: HPAG1_0745

Alternate gene names: NA

Gene position: 782899-781310 (Counterclockwise)

Preceding gene: 108563171

Following gene: 108563154

Centisome position: 49.04

GC content: 42.39

Gene sequence:

>1590_bases
ATGAGCAGCGGGTTAATTTACATTTCATTAGAAGTATTAGTAGCGTGTTTGATTACCGCTCTAATCATGTATTATGTGAT
GAAAAAGATCTATTACGCTAGAGGGCAAGCCGCTTTAAAAAGCGCTTCAGCTAAAGCCAAATTGATGGAGTTTCAAGCGA
AATCTTTTGTGGAAGCTGAAGAGGTGCGCATGAAAAGCCAAGAATGCAAATTGCAACAGCAATATGAAAACAAGAACTTG
CAACTAAAAACCCATTTTGAAAAAAAAGAAGTGCATTTGAAGCATTTAGAAGCGCAACACAAAGAATTTGTAAGAGATGA
AAAACGCTATTTAGAAAAGGAAAAAAAAGAGCTTGAAAAAGAACGCCAAATTTTAGAACAAGAAAAAGAAAATTTTAAAA
AACAGCGCGTTGTTTGCAAAGAAGCTCAAGCCAAAGCGCTAGACGCGATGCTCAATTACATGGCTTACACTAAAGATGAA
ATTAAAAACATGATTTTAGAGCAGTTAGAAGAAGAATTAGAAGCGCAAAAAAGCGCGTTAATCAGGCGTTATGAAAAAGA
AGCCAAAGAAGAGGGCAAGAAAAAATCGTATGCCATTTTAGCGGAAGCGACAGCCCGTTTTGCGGGTAATTATGCGACAG
AGAATTTAACAACTCGTATTGCTTTGCCTTGCTCAGATTATATCGGTCGTGTGATAGGCAAAGACGGGAAAAATATTGAA
GCGTTTAAAAAGGTCAGCGGGGTGGATATAGAATTTAGCGAAGATAGCAGCGAATTGTGTTTGTCCAGTTTCAATCTTTA
TCGGCGTGAAGTAGCGAGCGAGACGCTTAAAATTTTAATAGAAGACGGCCGTATCCAGCCTAACAGGATTGAAGAGGTTT
ATCATAGAGTCGCGCGCAACCTGGAAAAAGAATTGCTTTCTGAAGGGGAGAGCGTGGTGTTAGAATTAGAGCTTGGGGCT
ATGGAAGATGAGCTTAAAATTTTAATAGGCAAAATGCGTTACCGCTCCAGTTTTGGGCAAAACGCTTTACAGCATTCTAA
AGAAGTCGCTCTTTTAGCCGGCTTGATTGCAGAACAGCTTGGGGGGGATAAAAAGCTCGCCAGAAGAGCCGGTATTTTGC
ATGATATTGGTAAAGCGCTCACTCAAGAGCTTGGGAGAGACCATGTGAATTTAGGGGTTGAGGTGTGCAAGCGCCATAAA
GAAGACCCGGTTGTGATTAATGCGATTTATGCCCACCATGGGCATGAAGAGATTTTGAGCGTGGAGTGCGCGAGCGTGTG
CGCGGCTGATGCGCTTTCAGCAGGGCGTCCTGGGGCTAGAAGAAAGAGCGATGAAGAATACGCTAAACGCATGCAAGCTT
TAGAAGAGATTGCGTTAGAATTTGATGGGGTGGAAAAAGCGTATGCGATGGAGAGCGGGCGAGAATTAAGAGTGATTGTC
AAATCCAACCAAGTCAGGGACAATCAAGTGCCAATTATTGCCAGAAAGATCGCTAAAAAGATAGAAGAGAGCGCTCAGTA
TGTGGGCGAAGTGGGCGTGCAAGTGGTGCGAGAAAATCGTTTCAAAACGACCGCTACGCTCAAGCAATGA

Upstream 100 bases:

>100_bases
TTAGCGATAGCTAATGGTGTTCTTACAGACGCCTATGACATTGAAGCGGATCTTTATATGAATGCTCGTATCGTTATGAA
GAATAATAGAAGGAAACATT

Downstream 100 bases:

>100_bases
TCAAGCCTTTTTCCCGCACCTTTTCCATATGCCTTTAGAAAAAACTTTATAGTAGATGAATGAGCGCAAAAAAGTTTCTG
ATGCGATCACTACAAAAATA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MSSGLIYISLEVLVACLITALIMYYVMKKIYYARGQAALKSASAKAKLMEFQAKSFVEAEEVRMKSQECKLQQQYENKNL
QLKTHFEKKEVHLKHLEAQHKEFVRDEKRYLEKEKKELEKERQILEQEKENFKKQRVVCKEAQAKALDAMLNYMAYTKDE
IKNMILEQLEEELEAQKSALIRRYEKEAKEEGKKKSYAILAEATARFAGNYATENLTTRIALPCSDYIGRVIGKDGKNIE
AFKKVSGVDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARNLEKELLSEGESVVLELELGA
MEDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGRDHVNLGVEVCKRHK
EDPVVINAIYAHHGHEEILSVECASVCAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIV
KSNQVRDNQVPIIARKIAKKIEESAQYVGEVGVQVVRENRFKTTATLKQ

Sequences:

>Translated_529_residues
MSSGLIYISLEVLVACLITALIMYYVMKKIYYARGQAALKSASAKAKLMEFQAKSFVEAEEVRMKSQECKLQQQYENKNL
QLKTHFEKKEVHLKHLEAQHKEFVRDEKRYLEKEKKELEKERQILEQEKENFKKQRVVCKEAQAKALDAMLNYMAYTKDE
IKNMILEQLEEELEAQKSALIRRYEKEAKEEGKKKSYAILAEATARFAGNYATENLTTRIALPCSDYIGRVIGKDGKNIE
AFKKVSGVDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARNLEKELLSEGESVVLELELGA
MEDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGRDHVNLGVEVCKRHK
EDPVVINAIYAHHGHEEILSVECASVCAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIV
KSNQVRDNQVPIIARKIAKKIEESAQYVGEVGVQVVRENRFKTTATLKQ
>Mature_528_residues
SSGLIYISLEVLVACLITALIMYYVMKKIYYARGQAALKSASAKAKLMEFQAKSFVEAEEVRMKSQECKLQQQYENKNLQ
LKTHFEKKEVHLKHLEAQHKEFVRDEKRYLEKEKKELEKERQILEQEKENFKKQRVVCKEAQAKALDAMLNYMAYTKDEI
KNMILEQLEEELEAQKSALIRRYEKEAKEEGKKKSYAILAEATARFAGNYATENLTTRIALPCSDYIGRVIGKDGKNIEA
FKKVSGVDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARNLEKELLSEGESVVLELELGAM
EDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGRDHVNLGVEVCKRHKE
DPVVINAIYAHHGHEEILSVECASVCAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIVK
SNQVRDNQVPIIARKIAKKIEESAQYVGEVGVQVVRENRFKTTATLKQ

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA [H]

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675 [H]

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1 [H]

EC number: =3.1.4.16 [H]

Molecular weight: Translated: 60239; Mature: 60108

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGLIYISLEVLVACLITALIMYYVMKKIYYARGQAALKSASAKAKLMEFQAKSFVEAE
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVRMKSQECKLQQQYENKNLQLKTHFEKKEVHLKHLEAQHKEFVRDEKRYLEKEKKELEK
HHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERQILEQEKENFKKQRVVCKEAQAKALDAMLNYMAYTKDEIKNMILEQLEEELEAQKSAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRRYEKEAKEEGKKKSYAILAEATARFAGNYATENLTTRIALPCSDYIGRVIGKDGKNIE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHCCCCEEEEECCHHHHHHHHHCCCCCCHH
AFKKVSGVDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARN
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LEKELLSEGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQL
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
GGDKKLARRAGILHDIGKALTQELGRDHVNLGVEVCKRHKEDPVVINAIYAHHGHEEILS
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHH
VECASVCAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIV
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEE
KSNQVRDNQVPIIARKIAKKIEESAQYVGEVGVQVVRENRFKTTATLKQ
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure 
SSGLIYISLEVLVACLITALIMYYVMKKIYYARGQAALKSASAKAKLMEFQAKSFVEAE
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVRMKSQECKLQQQYENKNLQLKTHFEKKEVHLKHLEAQHKEFVRDEKRYLEKEKKELEK
HHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERQILEQEKENFKKQRVVCKEAQAKALDAMLNYMAYTKDEIKNMILEQLEEELEAQKSAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRRYEKEAKEEGKKKSYAILAEATARFAGNYATENLTTRIALPCSDYIGRVIGKDGKNIE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHCCCCEEEEECCHHHHHHHHHCCCCCCHH
AFKKVSGVDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARN
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LEKELLSEGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQL
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
GGDKKLARRAGILHDIGKALTQELGRDHVNLGVEVCKRHKEDPVVINAIYAHHGHEEILS
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHH
VECASVCAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIV
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEE
KSNQVRDNQVPIIARKIAKKIEESAQYVGEVGVQVVRENRFKTTATLKQ
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA