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The map label for this gene is rimO [H]

Identifier: 108563143

GI number: 108563143

Start: 756637

End: 757956

Strand: Reverse

Name: rimO [H]

Synonym: HPAG1_0718

Alternate gene names: 108563143

Gene position: 757956-756637 (Counterclockwise)

Preceding gene: 108563144

Following gene: 108563142

Centisome position: 47.48

GC content: 41.52

Gene sequence:

>1320_bases
ATGCAAGTTAAAGAAAACAAACAACTTTGCCTGATCTCATTAGGTTGTTCTAAAAATTTGGTGGATTCAGAGGTGATGTT
AGGCAAGCTTTATAATTACACGCTCACTAATGACGCTAAGAGCGCTGATGTGATTTTGATCAACACTTGCGGTTTTATTG
AAAGCGCTAAACAAGAGAGTATCCAAACCATTCTCAACGCCGCCAAAGACAAAAAAGAGGGAGCGATTTTGATTGCGAGC
GGGTGCTTGAGCGAGCGCTATAAAGATGAAATTAAAGAATTGATCCCTGAAGTGGATATTTTTACGGGCGTGGGGGATTA
TGACAAAATTGATATTTTGATCGCTAAAAAACAAAACCAGTTCAGCGAGCAAGTGTTTTTAAGCGAGCATTATAACGCGC
GCATCATCACCGGTTCTAGCGTGCATGCTTATGTGAAAATTTCTGAGGGCTGTAACCAAAAATGCTCTTTTTGCGCTATC
CCTAGCTTTAAGGGGAAATTGCAAAGCAGGGAATTGGACTCCATTTTAAAAGAAGTGGAAAATCTGGCTCTTAAAGGTTA
TAAGGATATGACTTTTATCGCTCAAGACTCTAGCTCGTTTTTATACGACAAGGGCCAAAAAGACGGCTTGATCCAGCTCA
TCAAAGCGATTGACAAACAGCAAGCCTTAAAAAGCGCTCGCATTCTATACCTCTACCCTTCTAGCACCACGCTAGAGCTT
ATTGGCGCGATTGAAAGTTCGCCCATTTTTCAAAATTATTTTGACATGCCCATCCAGCACATCAGCGACTCCATGCTTAA
AAAGATGCGGCGCAACTCCAGCCAAGCACACCATTTAAAGCTTTTAGATGCCATGAAGCAGGTTAAAGAAAGCTTTATCA
GAAGCACGATCATTGTAGGGCATCCGGAAGAAAATGAGGGCGAATTTGAGGAATTGAGCGCGTTTTTGGACGAGTTCCGG
TTTGACCGGTTGAATATTTTTGCTTTCAGCGCTGAAGAAAACACGCATGCCTATTCTTTAGAGAAAGTGCCTAAAAAAAC
CATCAACGCCCGCATCAAAGCCTTGAATAAAATCGCTTTAAAACACCAAAACCATTCCTTTAAGGCTTTGTTAAATAAGC
CCATTAAGGCGTTAGTGGAACATAAAGAGGGCGAGTATTTTTACAAAGCAAGGGATCTTAGGTGGGCGCCTGAAGTGGAT
GGGGAAATTTTAATCAATGATAGCGAATTAGCCACCCCTTTACAACCCGGGCATTATACGATTGTGCCTAGCGTCTTTAA
AGACAATATCTTACTCGCTAAGGTTTTAAGCCCTTTTTAA

Upstream 100 bases:

>100_bases
ACAAGCGCGAAATACAAAGCCGATGCGTTTTTAAAAGACGCTCCTGAATGGATTGATTTCTTTTGGGAAGTGGATTTGAA
AAATTTAAAAAGCCATTAAC

Downstream 100 bases:

>100_bases
AAGTTAGGGCTAAAAGCGCGGCTATAGCGTGGCTAGAGGGTGGGGGTTTGCGTTTTTTTTGTTAAAATGCGTCAGAAAAA
TTCGGCATGAGGGCAAAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: S12 MTTase; S12 methylthiotransferase; Ribosome maturation factor RimO [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MQVKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDAKSADVILINTCGFIESAKQESIQTILNAAKDKKEGAILIAS
GCLSERYKDEIKELIPEVDIFTGVGDYDKIDILIAKKQNQFSEQVFLSEHYNARIITGSSVHAYVKISEGCNQKCSFCAI
PSFKGKLQSRELDSILKEVENLALKGYKDMTFIAQDSSSFLYDKGQKDGLIQLIKAIDKQQALKSARILYLYPSSTTLEL
IGAIESSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLDAMKQVKESFIRSTIIVGHPEENEGEFEELSAFLDEFR
FDRLNIFAFSAEENTHAYSLEKVPKKTINARIKALNKIALKHQNHSFKALLNKPIKALVEHKEGEYFYKARDLRWAPEVD
GEILINDSELATPLQPGHYTIVPSVFKDNILLAKVLSPF

Sequences:

>Translated_439_residues
MQVKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDAKSADVILINTCGFIESAKQESIQTILNAAKDKKEGAILIAS
GCLSERYKDEIKELIPEVDIFTGVGDYDKIDILIAKKQNQFSEQVFLSEHYNARIITGSSVHAYVKISEGCNQKCSFCAI
PSFKGKLQSRELDSILKEVENLALKGYKDMTFIAQDSSSFLYDKGQKDGLIQLIKAIDKQQALKSARILYLYPSSTTLEL
IGAIESSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLDAMKQVKESFIRSTIIVGHPEENEGEFEELSAFLDEFR
FDRLNIFAFSAEENTHAYSLEKVPKKTINARIKALNKIALKHQNHSFKALLNKPIKALVEHKEGEYFYKARDLRWAPEVD
GEILINDSELATPLQPGHYTIVPSVFKDNILLAKVLSPF
>Mature_439_residues
MQVKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDAKSADVILINTCGFIESAKQESIQTILNAAKDKKEGAILIAS
GCLSERYKDEIKELIPEVDIFTGVGDYDKIDILIAKKQNQFSEQVFLSEHYNARIITGSSVHAYVKISEGCNQKCSFCAI
PSFKGKLQSRELDSILKEVENLALKGYKDMTFIAQDSSSFLYDKGQKDGLIQLIKAIDKQQALKSARILYLYPSSTTLEL
IGAIESSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLDAMKQVKESFIRSTIIVGHPEENEGEFEELSAFLDEFR
FDRLNIFAFSAEENTHAYSLEKVPKKTINARIKALNKIALKHQNHSFKALLNKPIKALVEHKEGEYFYKARDLRWAPEVD
GEILINDSELATPLQPGHYTIVPSVFKDNILLAKVLSPF

Specific function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 [H]

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI28872782, Length=464, Percent_Identity=25.4310344827586, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI28872784, Length=464, Percent_Identity=25.4310344827586, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI93277076, Length=371, Percent_Identity=24.2587601078167, Blast_Score=112, Evalue=9e-25,
Organism=Escherichia coli, GI1787057, Length=430, Percent_Identity=31.1627906976744, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786882, Length=393, Percent_Identity=26.4631043256997, Blast_Score=129, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17553146, Length=456, Percent_Identity=23.4649122807018, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71996771, Length=218, Percent_Identity=24.7706422018349, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356207, Length=455, Percent_Identity=23.5164835164835, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI19922432, Length=378, Percent_Identity=22.7513227513227, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR012340
- InterPro:   IPR007197
- InterPro:   IPR005840 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 49605; Mature: 49605

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDAKSADVILINTCGFIESAKQES
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHEEEECCCCCCCCEEEEECCCCHHHHHHHH
IQTILNAAKDKKEGAILIASGCLSERYKDEIKELIPEVDIFTGVGDYDKIDILIAKKQNQ
HHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCC
FSEQVFLSEHYNARIITGSSVHAYVKISEGCNQKCSFCAIPSFKGKLQSRELDSILKEVE
HHHHHHHHCCCCEEEEECCCEEEEEEECCCCCCCCCEEECCCHHCHHHHHHHHHHHHHHH
NLALKGYKDMTFIAQDSSSFLYDKGQKDGLIQLIKAIDKQQALKSARILYLYPSSTTLEL
HHHHCCCCCEEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHH
IGAIESSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLDAMKQVKESFIRSTIIVG
HHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCEEEEE
HPEENEGEFEELSAFLDEFRFDRLNIFAFSAEENTHAYSLEKVPKKTINARIKALNKIAL
CCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
KHQNHSFKALLNKPIKALVEHKEGEYFYKARDLRWAPEVDGEILINDSELATPLQPGHYT
HCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCEE
IVPSVFKDNILLAKVLSPF
EECHHHCCCCHHHHHHCCC
>Mature Secondary Structure
MQVKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDAKSADVILINTCGFIESAKQES
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHEEEECCCCCCCCEEEEECCCCHHHHHHHH
IQTILNAAKDKKEGAILIASGCLSERYKDEIKELIPEVDIFTGVGDYDKIDILIAKKQNQ
HHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCC
FSEQVFLSEHYNARIITGSSVHAYVKISEGCNQKCSFCAIPSFKGKLQSRELDSILKEVE
HHHHHHHHCCCCEEEEECCCEEEEEEECCCCCCCCCEEECCCHHCHHHHHHHHHHHHHHH
NLALKGYKDMTFIAQDSSSFLYDKGQKDGLIQLIKAIDKQQALKSARILYLYPSSTTLEL
HHHHCCCCCEEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHH
IGAIESSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLDAMKQVKESFIRSTIIVG
HHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCEEEEE
HPEENEGEFEELSAFLDEFRFDRLNIFAFSAEENTHAYSLEKVPKKTINARIKALNKIAL
CCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
KHQNHSFKALLNKPIKALVEHKEGEYFYKARDLRWAPEVDGEILINDSELATPLQPGHYT
HCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCEE
IVPSVFKDNILLAKVLSPF
EECHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA