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The map label for this gene is dcrA [H]

Identifier: 108563004

GI number: 108563004

Start: 596642

End: 597943

Strand: Reverse

Name: dcrA [H]

Synonym: HPAG1_0579

Alternate gene names: 108563004

Gene position: 597943-596642 (Counterclockwise)

Preceding gene: 108563005

Following gene: 108563003

Centisome position: 37.46

GC content: 38.94

Gene sequence:

>1302_bases
ATGTTTGGGAATAAGCAGTTGCAACTTCAGATCAGTCAAAAAGATTCTGAAATTACGGAGTTAAAAAAAGAAATCAATCT
CTATCAAAGCCTTTTAAATTTGTGCTTGCATGAAGGTTTTGTAGGTATTAAAAACAATAAAGTCGTTTTTAAGAGTGGGA
ATCTTGCAAGCTTAAACAATTTAGAAGAACAAAGCGTTCATTTCAAAGAAAATGCAGAGAGCGTTAATTTACAAGGGGTT
TCTTATTCTTTAAAAAGCCAAAATATTGATGGCGTGCAGTATTTTTCGTTGGCTAAAAACACAAGTTGTGTGGGGGAATA
CCATAAAAATGATTTGTTTAAGACTTTTTGCGCGAGCTTAAAAGAAGGCTTAGAGAACGCACAAGAAAGCATGCAGTATT
TCCATCAAGAAACCGGTGCTCTTTTAAATGCGGCTAAAAATGGCGAAGCGCATTCTACTGAAGGATTAGGGACCGTTAAT
AAAACGGGGCAAGACATTGAATCGCTTTATGAAAAGATGCAAAACGCCACTTCGTTAGCGGACTCTCTCAACCAACGGAG
TAATGAAATCACTCAAGTCATTTCTTTGATTGATGATATTGCAGAACAAACCAATCTCTTAGCCCTAAACGCCGCTATTG
AGGCCGCGCGAGCGGGCGAGCATGGGAGAGGGTTTGCGGTGGTGGCTGATGAGGTGAGAAAACTCGCTGAAAAAACCCAA
AAAGCCACTAAAGAAATCGCCGTTGTCGTTAAAAGCATGCAACAAGAAGCGAACGATATTCAAACCAATACCCACGATAT
TAATTCCATTGTAGGTTCTATTAAGGGCGATGTGGAAGAGCTTAAATCCACCGTAAAAAATAACATGATTGTCGCGCAAG
CGGCAAAATACACCATCTACAATGTCAATAACCGGGTGTTTTGCGGTCTGGCCAAACTTGATCATGTGGTCTTTAAAAAC
AATCTTTATGGCATGGTTTTTGGTCTCAATTCCTTTGACATTACCAGCCATAAGAATTGCCGCTTAGGCAAATGGTATTA
TGAGGGTGCGGGCAAAGAGAATTTTTCCAACACTTCAGGCTATAGAGCTTTAGAAAGCCACCATGCGAGCGTGCATGCTG
AAGCTAATGATTTGGTTAAAGCCGTTCAAGAGGACCACATTACCGATTCAAAATACCTAGAGCATAAAGTGCATTTAATG
GAAGATAGCGCTAAACATGTTAGAGAAAATATTGATAAGATGTTTTATGAAAAACAAGATGAACTCAATAAAATCATTGA
AAAAATCCAAAAAGGCGAATGA

Upstream 100 bases:

>100_bases
CTGAATTGTTTTTGAAGCAACAATACTAACGAGCGATTAAAATGTTTGGTAATTTTGGGTATAATCCCAAAAGATTCAAA
TTTAAATAAGGAATGCCACC

Downstream 100 bases:

>100_bases
TTTTATTCAATGAAGTGTTTTGATGTTTTCTAAATCTTTAGAAGCCCTACGCCATGCCAAACGCTACCGCAAAAGAGAGT
TGTTTGACCCTTCATTAAAG

Product: hemolysin secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MFGNKQLQLQISQKDSEITELKKEINLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNNLEEQSVHFKENAESVNLQGV
SYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASLKEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVN
KTGQDIESLYEKMQNATSLADSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
KATKEIAVVVKSMQQEANDIQTNTHDINSIVGSIKGDVEELKSTVKNNMIVAQAAKYTIYNVNNRVFCGLAKLDHVVFKN
NLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSGYRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLM
EDSAKHVRENIDKMFYEKQDELNKIIEKIQKGE

Sequences:

>Translated_433_residues
MFGNKQLQLQISQKDSEITELKKEINLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNNLEEQSVHFKENAESVNLQGV
SYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASLKEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVN
KTGQDIESLYEKMQNATSLADSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
KATKEIAVVVKSMQQEANDIQTNTHDINSIVGSIKGDVEELKSTVKNNMIVAQAAKYTIYNVNNRVFCGLAKLDHVVFKN
NLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSGYRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLM
EDSAKHVRENIDKMFYEKQDELNKIIEKIQKGE
>Mature_433_residues
MFGNKQLQLQISQKDSEITELKKEINLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNNLEEQSVHFKENAESVNLQGV
SYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASLKEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVN
KTGQDIESLYEKMQNATSLADSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
KATKEIAVVVKSMQQEANDIQTNTHDINSIVGSIKGDVEELKSTVKNNMIVAQAAKYTIYNVNNRVFCGLAKLDHVVFKN
NLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSGYRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLM
EDSAKHVRENIDKMFYEKQDELNKIIEKIQKGE

Specific function: Receptor For The Attractant L-Aspartate And Related Amino And Dicarboxylic Acids. Tar Also Mediates Taxis To The Attractant Maltose VIa An Interaction With The Periplasmic Maltose Binding Protein. Tar Mediates Taxis Away From The Repellents Cobalt And Ni

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=116, Percent_Identity=45.6896551724138, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI2367378, Length=89, Percent_Identity=48.314606741573, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788194, Length=152, Percent_Identity=40.7894736842105, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789453, Length=203, Percent_Identity=32.512315270936, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787690, Length=84, Percent_Identity=48.8095238095238, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 48362; Mature: 48362

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGNKQLQLQISQKDSEITELKKEINLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNN
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCHHHCC
LEEQSVHFKENAESVNLQGVSYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASL
CHHHHHHHHCCCCEEEEECEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVNKTGQDIESLYEKMQNATSLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
HHHHHHHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHH
KATKEIAVVVKSMQQEANDIQTNTHDINSIVGSIKGDVEELKSTVKNNMIVAQAAKYTIY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECEEEEE
NVNNRVFCGLAKLDHVVFKNNLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSG
ECCCEEEEEHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCC
YRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLMEDSAKHVRENIDKMFYEKQD
HHHHHHHCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNKIIEKIQKGE
HHHHHHHHHHCCC
>Mature Secondary Structure
MFGNKQLQLQISQKDSEITELKKEINLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNN
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCHHHCC
LEEQSVHFKENAESVNLQGVSYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASL
CHHHHHHHHCCCCEEEEECEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVNKTGQDIESLYEKMQNATSLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
HHHHHHHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHH
KATKEIAVVVKSMQQEANDIQTNTHDINSIVGSIKGDVEELKSTVKNNMIVAQAAKYTIY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECEEEEE
NVNNRVFCGLAKLDHVVFKNNLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSG
ECCCEEEEEHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCC
YRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLMEDSAKHVRENIDKMFYEKQD
HHHHHHHCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNKIIEKIQKGE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1548224 [H]