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The map label for this gene is 108562864

Identifier: 108562864

GI number: 108562864

Start: 450161

End: 452467

Strand: Reverse

Name: 108562864

Synonym: HPAG1_0439

Alternate gene names: NA

Gene position: 452467-450161 (Counterclockwise)

Preceding gene: 108562865

Following gene: 108562863

Centisome position: 28.34

GC content: 35.59

Gene sequence:

>2307_bases
ATGTTTGCGAGCTTGAATGTTTTAAAAGAATTGCAAAAGCATTATGAAACCGACCCAAACCCAAAAGATCCCCTAAAAGG
CATCATCTGGCACACGCAAGGCAGCGGTAAAACCGCTTTAACCTACCATTTAACCAAACTCATCAGAGACTTTTTTAGCC
CGCTAAACAAAAAGACTAAATTTTATTTTATTGTGGACAGGTTGGATTTATTAGAACAAGCCAAAAACGAGTTTTTAAAA
AGAGGCCTTTGTGCGCATGAGGCAGAAAATAAAGAGGATTTGAGTCAAAAATTAAAAAGCTCTAGCGTGTTTGAAAACCC
TCAAGGGAATGATGAAATCATCGTTGTGAATATCCAAAAATTCAAAGCCCCCAATGAAGAAAAAGCCCCCAATGAAGAAA
AAGCCCCCAATGAAGACCCCTCTAATAGCACTCCTAAAGAAATCATTTCTAAAACAGAATTACAAGCATCCATTCAAAAC
AGCCGCAATTTACAAAGGGTATTTATCATAGATGAAGCCCACAGGAGCTATGACCCTAAAGGTTGCTTTTATGCCAATTT
GATAGAATGCGACAAGACAGCGATTAAAATCGCCCTCACAGGCACGCCCCTGTTAGAAGACAACGCGCAAGATAAAGCCA
CTAAAAACACTTTTGGCAACTACTTGCACACCTATTCTTATACAGAATCCATTAAAGACAAACACACCCTAACGCTCCAG
TTAGAAAGCATTGAAACGAGCTACAAAGAAAAATTACAAGCAATCTATCGCCTTTTACAAGAAAGCATCACTATTGAAGA
CATAGAGGTTAAAAAAGAAACGATTTTTAATCATGAAAGATACATTAAAGAAATGCTCTTTTATATCATCAGAGATTTAT
TGAATTTCAGGCGTGTAAATAATGATGAAAATTTAAAGGCTATGGTGGTTTGTTTTTCAAGCGCCCAAGCCAAGTTAGCC
AATTTATTTTTTAATGAAGTCCAAGAAAAAGTCTTACAAGAAAACCCTAACCTGAAAATTTTAAACAAACTCAAATCCAG
CCTCATTTTGCATGACGAACAAGAAGTCAAAGAAAAGATTCATTCTTTTAAACATGAAGATACGGATATAGTCTTTGTGT
TTAACATGCTTTTAACCGGCTTTGATTTACCCAGTCTCAAACGCCTTTATATCCACAGAGAATTAAAAGATCACAATTTG
CTCCAAGCCCTAGCCAGAGTGAATCGCTCCTATAACAACATGTCTTTTGGCTATCTTATAGATTTCGTAGGGATTCAAGA
GAATTTTGACAAAACGACTGATGATTACTTGAAAGAATTAAACCGATTCAATCAAAGCGGTGCCCATAGCGATTCTAATA
TCAAAGACATCTTTGCGGATCGTAAGACTTTAGAAGAAGACATTAAAAACGCCTATGATGATCTTTTTGATTACCCCATT
GACGATATAGAGGCCATGACTAGCGCCATTGTTAGTATCAGCGAAATGAGTGAGCTTTTAAAAGTCTCACAAGCCATTAA
CACGCTTAAAGAGCGCTACAATTTAATCCGCACTTCTAGCGATGAAAAAATCCTTTCCTTAAAAGAAAAAATGGATATTG
AAAAGATCAATAAAATCTCTTCAATGCTTCATCAAAAAGCCAAATACCTCCATGCGTTAAAAAATATCAATGAGCCTAAA
AACCCAAACGATTTAATGATTTTAGAAGACCTCATCGCTCTTTTAGACTTTAAAATAGAGTTTAAAGAACGCAAAGAATT
ACGCTTTAAAGAACAAGAAGAAATTACCACCAAACAAAAGCAAGCTAAAGAGATTTTAGAAAAAATCCCGGATCAACAAG
ATAAAGAAATCCAAAAGTTTTACAAAGACTTTTCAAAACTACTCCAAACGCCCGCAACAAGCCAGAATTTTGAGGAAATT
TCTCATTCCTATGATGCGATCATTTCACAACTCAAACAACACAAAGAACAAACCACCCACTTATTAAATAAATACGACAA
TGATTTATCGTATGCGATCACGCATCAGCGCCTTCATAAGCGCCTTATGGAAGAAAACATTTCTAATCCAACGGGAATTT
TCACGATTTTAAGCGCCTTAAAAAAATCTATTGATGAGCGTATTTCTAAGCGTCAAGAAATCTTAAACGAAGAATATCAC
CTAAAAAATGCCATAAAACTAGAATTAAGGAACGCTTTCAAAGAAAACCCCTCCTTAAAAGATTTGGAAAAAGAAAAAGA
ACTTATCATTCAAACCCTTTTTAACGAACTCACACAAAACCACCATCAAGGAAATTCACATGCCTAA

Upstream 100 bases:

>100_bases
GTTTTGATCCCCAAAAAGGCTTTGCTTTATCCTAAAATACGGCATCAGTTTCTTAAAAGAAAGATCAGAGTTTAAAAAAC
ACATTTGGCGTTATGCGCAG

Downstream 100 bases:

>100_bases
TAACGCTTTATTGCAAATCAAACAAGACACCCTAAGCCTCATTGATGATTTAAAAGTCATTTGCGCAAGTTTTGGTTTAG
GGAATGACGGCAACGAATAC

Product: type I restriction enzyme R protein

Products: NA

Alternate protein names: Putative type I restriction enzyme MjaXP R protein [H]

Number of amino acids: Translated: 768; Mature: 768

Protein sequence:

>768_residues
MFASLNVLKELQKHYETDPNPKDPLKGIIWHTQGSGKTALTYHLTKLIRDFFSPLNKKTKFYFIVDRLDLLEQAKNEFLK
RGLCAHEAENKEDLSQKLKSSSVFENPQGNDEIIVVNIQKFKAPNEEKAPNEEKAPNEDPSNSTPKEIISKTELQASIQN
SRNLQRVFIIDEAHRSYDPKGCFYANLIECDKTAIKIALTGTPLLEDNAQDKATKNTFGNYLHTYSYTESIKDKHTLTLQ
LESIETSYKEKLQAIYRLLQESITIEDIEVKKETIFNHERYIKEMLFYIIRDLLNFRRVNNDENLKAMVVCFSSAQAKLA
NLFFNEVQEKVLQENPNLKILNKLKSSLILHDEQEVKEKIHSFKHEDTDIVFVFNMLLTGFDLPSLKRLYIHRELKDHNL
LQALARVNRSYNNMSFGYLIDFVGIQENFDKTTDDYLKELNRFNQSGAHSDSNIKDIFADRKTLEEDIKNAYDDLFDYPI
DDIEAMTSAIVSISEMSELLKVSQAINTLKERYNLIRTSSDEKILSLKEKMDIEKINKISSMLHQKAKYLHALKNINEPK
NPNDLMILEDLIALLDFKIEFKERKELRFKEQEEITTKQKQAKEILEKIPDQQDKEIQKFYKDFSKLLQTPATSQNFEEI
SHSYDAIISQLKQHKEQTTHLLNKYDNDLSYAITHQRLHKRLMEENISNPTGIFTILSALKKSIDERISKRQEILNEEYH
LKNAIKLELRNAFKENPSLKDLEKEKELIIQTLFNELTQNHHQGNSHA

Sequences:

>Translated_768_residues
MFASLNVLKELQKHYETDPNPKDPLKGIIWHTQGSGKTALTYHLTKLIRDFFSPLNKKTKFYFIVDRLDLLEQAKNEFLK
RGLCAHEAENKEDLSQKLKSSSVFENPQGNDEIIVVNIQKFKAPNEEKAPNEEKAPNEDPSNSTPKEIISKTELQASIQN
SRNLQRVFIIDEAHRSYDPKGCFYANLIECDKTAIKIALTGTPLLEDNAQDKATKNTFGNYLHTYSYTESIKDKHTLTLQ
LESIETSYKEKLQAIYRLLQESITIEDIEVKKETIFNHERYIKEMLFYIIRDLLNFRRVNNDENLKAMVVCFSSAQAKLA
NLFFNEVQEKVLQENPNLKILNKLKSSLILHDEQEVKEKIHSFKHEDTDIVFVFNMLLTGFDLPSLKRLYIHRELKDHNL
LQALARVNRSYNNMSFGYLIDFVGIQENFDKTTDDYLKELNRFNQSGAHSDSNIKDIFADRKTLEEDIKNAYDDLFDYPI
DDIEAMTSAIVSISEMSELLKVSQAINTLKERYNLIRTSSDEKILSLKEKMDIEKINKISSMLHQKAKYLHALKNINEPK
NPNDLMILEDLIALLDFKIEFKERKELRFKEQEEITTKQKQAKEILEKIPDQQDKEIQKFYKDFSKLLQTPATSQNFEEI
SHSYDAIISQLKQHKEQTTHLLNKYDNDLSYAITHQRLHKRLMEENISNPTGIFTILSALKKSIDERISKRQEILNEEYH
LKNAIKLELRNAFKENPSLKDLEKEKELIIQTLFNELTQNHHQGNSHA
>Mature_768_residues
MFASLNVLKELQKHYETDPNPKDPLKGIIWHTQGSGKTALTYHLTKLIRDFFSPLNKKTKFYFIVDRLDLLEQAKNEFLK
RGLCAHEAENKEDLSQKLKSSSVFENPQGNDEIIVVNIQKFKAPNEEKAPNEEKAPNEDPSNSTPKEIISKTELQASIQN
SRNLQRVFIIDEAHRSYDPKGCFYANLIECDKTAIKIALTGTPLLEDNAQDKATKNTFGNYLHTYSYTESIKDKHTLTLQ
LESIETSYKEKLQAIYRLLQESITIEDIEVKKETIFNHERYIKEMLFYIIRDLLNFRRVNNDENLKAMVVCFSSAQAKLA
NLFFNEVQEKVLQENPNLKILNKLKSSLILHDEQEVKEKIHSFKHEDTDIVFVFNMLLTGFDLPSLKRLYIHRELKDHNL
LQALARVNRSYNNMSFGYLIDFVGIQENFDKTTDDYLKELNRFNQSGAHSDSNIKDIFADRKTLEEDIKNAYDDLFDYPI
DDIEAMTSAIVSISEMSELLKVSQAINTLKERYNLIRTSSDEKILSLKEKMDIEKINKISSMLHQKAKYLHALKNINEPK
NPNDLMILEDLIALLDFKIEFKERKELRFKEQEEITTKQKQAKEILEKIPDQQDKEIQKFYKDFSKLLQTPATSQNFEEI
SHSYDAIISQLKQHKEQTTHLLNKYDNDLSYAITHQRLHKRLMEENISNPTGIFTILSALKKSIDERISKRQEILNEEYH
LKNAIKLELRNAFKENPSLKDLEKEKELIIQTLFNELTQNHHQGNSHA

Specific function: Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG0610

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR021810
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR011254
- InterPro:   IPR004473
- InterPro:   IPR006935
- InterPro:   IPR007409 [H]

Pfam domain/function: PF11867 DUF3387; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 89693; Mature: 89693

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFASLNVLKELQKHYETDPNPKDPLKGIIWHTQGSGKTALTYHLTKLIRDFFSPLNKKTK
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCE
FYFIVDRLDLLEQAKNEFLKRGLCAHEAENKEDLSQKLKSSSVFENPQGNDEIIVVNIQK
EEEHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEHH
FKAPNEEKAPNEEKAPNEDPSNSTPKEIISKTELQASIQNSRNLQRVFIIDEAHRSYDPK
HCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCC
GCFYANLIECDKTAIKIALTGTPLLEDNAQDKATKNTFGNYLHTYSYTESIKDKHTLTLQ
CCEEHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LESIETSYKEKLQAIYRLLQESITIEDIEVKKETIFNHERYIKEMLFYIIRDLLNFRRVN
EHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDENLKAMVVCFSSAQAKLANLFFNEVQEKVLQENPNLKILNKLKSSLILHDEQEVKEKI
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
HSFKHEDTDIVFVFNMLLTGFDLPSLKRLYIHRELKDHNLLQALARVNRSYNNMSFGYLI
HHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DFVGIQENFDKTTDDYLKELNRFNQSGAHSDSNIKDIFADRKTLEEDIKNAYDDLFDYPI
HHHCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
DDIEAMTSAIVSISEMSELLKVSQAINTLKERYNLIRTSSDEKILSLKEKMDIEKINKIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
SMLHQKAKYLHALKNINEPKNPNDLMILEDLIALLDFKIEFKERKELRFKEQEEITTKQK
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHH
QAKEILEKIPDQQDKEIQKFYKDFSKLLQTPATSQNFEEISHSYDAIISQLKQHKEQTTH
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLNKYDNDLSYAITHQRLHKRLMEENISNPTGIFTILSALKKSIDERISKRQEILNEEYH
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKNAIKLELRNAFKENPSLKDLEKEKELIIQTLFNELTQNHHQGNSHA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFASLNVLKELQKHYETDPNPKDPLKGIIWHTQGSGKTALTYHLTKLIRDFFSPLNKKTK
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCE
FYFIVDRLDLLEQAKNEFLKRGLCAHEAENKEDLSQKLKSSSVFENPQGNDEIIVVNIQK
EEEHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEHH
FKAPNEEKAPNEEKAPNEDPSNSTPKEIISKTELQASIQNSRNLQRVFIIDEAHRSYDPK
HCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCC
GCFYANLIECDKTAIKIALTGTPLLEDNAQDKATKNTFGNYLHTYSYTESIKDKHTLTLQ
CCEEHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LESIETSYKEKLQAIYRLLQESITIEDIEVKKETIFNHERYIKEMLFYIIRDLLNFRRVN
EHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDENLKAMVVCFSSAQAKLANLFFNEVQEKVLQENPNLKILNKLKSSLILHDEQEVKEKI
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
HSFKHEDTDIVFVFNMLLTGFDLPSLKRLYIHRELKDHNLLQALARVNRSYNNMSFGYLI
HHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DFVGIQENFDKTTDDYLKELNRFNQSGAHSDSNIKDIFADRKTLEEDIKNAYDDLFDYPI
HHHCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
DDIEAMTSAIVSISEMSELLKVSQAINTLKERYNLIRTSSDEKILSLKEKMDIEKINKIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
SMLHQKAKYLHALKNINEPKNPNDLMILEDLIALLDFKIEFKERKELRFKEQEEITTKQK
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHH
QAKEILEKIPDQQDKEIQKFYKDFSKLLQTPATSQNFEEISHSYDAIISQLKQHKEQTTH
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLNKYDNDLSYAITHQRLHKRLMEENISNPTGIFTILSALKKSIDERISKRQEILNEEYH
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKNAIKLELRNAFKENPSLKDLEKEKELIIQTLFNELTQNHHQGNSHA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]