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The map label for this gene is 108562862

Identifier: 108562862

GI number: 108562862

Start: 447285

End: 448544

Strand: Reverse

Name: 108562862

Synonym: HPAG1_0437

Alternate gene names: NA

Gene position: 448544-447285 (Counterclockwise)

Preceding gene: 108562863

Following gene: 108562861

Centisome position: 28.1

GC content: 31.98

Gene sequence:

>1260_bases
ATGACTAAACTTTTAGATTTAAAAAATAATTCAGTAATTACTATCAATCAAAACAACTACACTAAAGAAGACAATTACAA
AAAAGTTTATTATTTAGATACTGATAATATCACAAACAATAAAATAAATGCTTTTCTAAAAATTGATTTAACAAAAGAAA
AATTGCCTTCAAGAGCTAAACGAAAATGCTCCATTAATAGCATTATTTATTCTAGTGTAAGACCTAACCAACGCCACTTT
GGGATTATCAAAGAAATTCCCAAAAATTTTTTAGTTTCTACCGCTTTTATCGTAATAGATATTATAGACTTAAAAAAATT
AGACCCTAATTATTTGTATTACTATATTACGCAAGATAAAATCACTCATTACTTGCAACGCATTGCAGAATGTGGGACTT
CTAGCTACCCCTCTATCACGCCCTTAGATTTTCTTAATATTAAAATCAAACTTTACCCACTAGAAACACAACAAAAAATC
GCCCGCACGCTTTCTGTCTTAGATCAAAAAATAGAGAACAACCACAAAATCAATGAGCTTTTACACAAGATCCTAGAACT
TCTTTATGAGCAATACTTCGTTCGTTTTGATTTTTTAGATGAAAACAACAAACCCTATCAAACTAGCGGCGGGAAAATGA
AATTCTCTAAAGAATTAAACCGCCTTATCCCCAACGATTTTGAAGTCAAAACGCTAGGGGATAATCCCCTATGTAACACG
ATCAAAACCGGAGTAACCCCCTTTAAACAAAAAGTGTATTATGAAACAAAACATATACAAGAAACCCTATCTCTTAATCA
AGGACTTAAAGTTAGCTATAACAAACGCCCTAATAGAGCCAACATGCAACCCACCATATACTCAGTATGGTTTGCCAAAA
TGAAAGACACTAAAAAACATTTATTTTTAAACCAACACATGCAATCATGGATAAAAGAAAGCATATTATCCACAGGTTTT
TGTGGCTTGCAATGTCAAAAACATACTTTTGAATACATAGCTTCCACGATCAAATACTCCCCTTTTGAAACAAGAAAAAA
TAATCTAGCGACCGGTGCTACACAAAAAGCTATCAACATTGAGATGCTAGACTATATTTTCATTCTTATACCAAATAAAG
AGCTACTAGATAATTATTCTAAAATAACTAAACCACTCTATGAAAAAATCTCTAATAATATCATTGAAGCCCAAACCCTA
ACCGCGCTCAGAGACTTTCTACTCCCCCTACTCTTAAAACAGCAAGTCAAACCTAAATAA

Upstream 100 bases:

>100_bases
GAAAACCTAATGCAACAATATTCAAGCGAATTAACAAGCCTTTTTGATGAAAGCCAGAGCTTGCAACAAGAAATTTTAGA
AACTTTAGGAAATCTTAATT

Downstream 100 bases:

>100_bases
AAAACCTTATAGTAAAACTCATTTCCTTAAGGGGATAGGGGGTATTTTGCGATAACACCCCCCTTAACCCCCTTAAAATC
CCCCTAACCCCCTAAGACCG

Product: type I restriction enzyme S protein

Products: NA

Alternate protein names: S.HindVIIP; Type I restriction enzyme HindVIIP specificity protein; S protein [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTKLLDLKNNSVITINQNNYTKEDNYKKVYYLDTDNITNNKINAFLKIDLTKEKLPSRAKRKCSINSIIYSSVRPNQRHF
GIIKEIPKNFLVSTAFIVIDIIDLKKLDPNYLYYYITQDKITHYLQRIAECGTSSYPSITPLDFLNIKIKLYPLETQQKI
ARTLSVLDQKIENNHKINELLHKILELLYEQYFVRFDFLDENNKPYQTSGGKMKFSKELNRLIPNDFEVKTLGDNPLCNT
IKTGVTPFKQKVYYETKHIQETLSLNQGLKVSYNKRPNRANMQPTIYSVWFAKMKDTKKHLFLNQHMQSWIKESILSTGF
CGLQCQKHTFEYIASTIKYSPFETRKNNLATGATQKAINIEMLDYIFILIPNKELLDNYSKITKPLYEKISNNIIEAQTL
TALRDFLLPLLLKQQVKPK

Sequences:

>Translated_419_residues
MTKLLDLKNNSVITINQNNYTKEDNYKKVYYLDTDNITNNKINAFLKIDLTKEKLPSRAKRKCSINSIIYSSVRPNQRHF
GIIKEIPKNFLVSTAFIVIDIIDLKKLDPNYLYYYITQDKITHYLQRIAECGTSSYPSITPLDFLNIKIKLYPLETQQKI
ARTLSVLDQKIENNHKINELLHKILELLYEQYFVRFDFLDENNKPYQTSGGKMKFSKELNRLIPNDFEVKTLGDNPLCNT
IKTGVTPFKQKVYYETKHIQETLSLNQGLKVSYNKRPNRANMQPTIYSVWFAKMKDTKKHLFLNQHMQSWIKESILSTGF
CGLQCQKHTFEYIASTIKYSPFETRKNNLATGATQKAINIEMLDYIFILIPNKELLDNYSKITKPLYEKISNNIIEAQTL
TALRDFLLPLLLKQQVKPK
>Mature_418_residues
TKLLDLKNNSVITINQNNYTKEDNYKKVYYLDTDNITNNKINAFLKIDLTKEKLPSRAKRKCSINSIIYSSVRPNQRHFG
IIKEIPKNFLVSTAFIVIDIIDLKKLDPNYLYYYITQDKITHYLQRIAECGTSSYPSITPLDFLNIKIKLYPLETQQKIA
RTLSVLDQKIENNHKINELLHKILELLYEQYFVRFDFLDENNKPYQTSGGKMKFSKELNRLIPNDFEVKTLGDNPLCNTI
KTGVTPFKQKVYYETKHIQETLSLNQGLKVSYNKRPNRANMQPTIYSVWFAKMKDTKKHLFLNQHMQSWIKESILSTGFC
GLQCQKHTFEYIASTIKYSPFETRKNNLATGATQKAINIEMLDYIFILIPNKELLDNYSKITKPLYEKISNNIIEAQTLT
ALRDFLLPLLLKQQVKPK

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity [H]

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 49061; Mature: 48929

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLLDLKNNSVITINQNNYTKEDNYKKVYYLDTDNITNNKINAFLKIDLTKEKLPSRAK
CCCEEEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECHHHCCHHHH
RKCSINSIIYSSVRPNQRHFGIIKEIPKNFLVSTAFIVIDIIDLKKLDPNYLYYYITQDK
HCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCEEEEEEEHHH
ITHYLQRIAECGTSSYPSITPLDFLNIKIKLYPLETQQKIARTLSVLDQKIENNHKINEL
HHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHH
LHKILELLYEQYFVRFDFLDENNKPYQTSGGKMKFSKELNRLIPNDFEVKTLGDNPLCNT
HHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEHHHHHHHHCCCCCEEEECCCCCCHHH
IKTGVTPFKQKVYYETKHIQETLSLNQGLKVSYNKRPNRANMQPTIYSVWFAKMKDTKKH
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
LFLNQHMQSWIKESILSTGFCGLQCQKHTFEYIASTIKYSPFETRKNNLATGATQKAINI
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCCCCHHCCCCCCCCCCHHHEEE
EMLDYIFILIPNKELLDNYSKITKPLYEKISNNIIEAQTLTALRDFLLPLLLKQQVKPK
EEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKLLDLKNNSVITINQNNYTKEDNYKKVYYLDTDNITNNKINAFLKIDLTKEKLPSRAK
CCEEEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECHHHCCHHHH
RKCSINSIIYSSVRPNQRHFGIIKEIPKNFLVSTAFIVIDIIDLKKLDPNYLYYYITQDK
HCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCEEEEEEEHHH
ITHYLQRIAECGTSSYPSITPLDFLNIKIKLYPLETQQKIARTLSVLDQKIENNHKINEL
HHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHH
LHKILELLYEQYFVRFDFLDENNKPYQTSGGKMKFSKELNRLIPNDFEVKTLGDNPLCNT
HHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEHHHHHHHHCCCCCEEEECCCCCCHHH
IKTGVTPFKQKVYYETKHIQETLSLNQGLKVSYNKRPNRANMQPTIYSVWFAKMKDTKKH
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
LFLNQHMQSWIKESILSTGFCGLQCQKHTFEYIASTIKYSPFETRKNNLATGATQKAINI
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCCCCHHCCCCCCCCCCHHHEEE
EMLDYIFILIPNKELLDNYSKITKPLYEKISNNIIEAQTLTALRDFLLPLLLKQQVKPK
EEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]