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The map label for this gene is cdsA [H]

Identifier: 108562641

GI number: 108562641

Start: 221294

End: 222094

Strand: Direct

Name: cdsA [H]

Synonym: HPAG1_0216

Alternate gene names: 108562641

Gene position: 221294-222094 (Clockwise)

Preceding gene: 108562640

Following gene: 108562642

Centisome position: 13.86

GC content: 43.07

Gene sequence:

>801_bases
GTGAAAGAAGAGTTATTTAAAGAAAAATCTCGTTACATTACAGGGTTTGTTTTAATCATTGCGGCAGGCTTGATTTTATA
TGCGGACAATTTGTTGTTGTTTTGGGCGGTTTTAGGGGGGATTTATCTAGTAGGGTTTTCTGAAGCGTTAAGACTATTCC
AAGTTAAAGCGAGCTTTAGCCTGTATTTCATTTTAGTGTTGTCATGGGTGGCGGCGTATTTTAACGGGCGCCCTATAGAA
TGCGCTCTTATCAGTGCGATGGTCATGGCTAGCATCATTGCTTATCAAAAAGTGCACCATAGCGAAGCCATTTTACCCTT
TTTATACCCGGGCGTTGGGTTTTTTGCACTTTTTGGGGTTTATAAGGATTTTGGTGCAGTAGCGATCATTTGGCTTTTAG
TCGTGGTGGTTGCAAGCGATGTGGGGGCGTTTTTTGGAGGCAAGCTTTTAGGCAAAACCCCTTTCACGCCCACTTCACCG
AATAAAACCTTAGAGGGCGCGTTGATTGGCGTTGTTTTGGCGAGTGTTTTAGGATCGTTTGTGGGCATGGGGAAATTGAG
CGGAGGCTTTTTTATGGCGCTTCTATTTAGTTTTTTAATCGCTCTTATGGCGGTGTTTGGGGATTTGTATGAAAGCTATT
TGAAAAGAAAGGTCGGGATCAAAGATAGCGGTAAGATTTTACCTGGGCATGGGGGCGTTTTAGACCGATTGGATTCCATG
CTTTTTGGGGCTTTAGGCTTGCATGCGTTGTTGTATTTTTTAGAAATTTGGAAAGAAACGGCGGTGTTTTTGGGGGATTG
A

Upstream 100 bases:

>100_bases
GATTAAAGCCGGTTTGTGGCTTAATTTGGTGGGCGTTGTTTTGATTAGCGCGTTTAGCTATTGTTTAGTTTCGCTGGTAT
TTAATTGATTAAGGAAAAAA

Downstream 100 bases:

>100_bases
ATGGTTGTTTTAGGAAGCACCGGCTCTATTGGGAAAAACGCCCTAAAAATCGCAAAAAAATTTGGCGTAGAAATAGAAGC
CTTGAGCTGTGGGAAAAATA

Product: CDP-diacylglycerol synthetase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKEELFKEKSRYITGFVLIIAAGLILYADNLLLFWAVLGGIYLVGFSEALRLFQVKASFSLYFILVLSWVAAYFNGRPIE
CALISAMVMASIIAYQKVHHSEAILPFLYPGVGFFALFGVYKDFGAVAIIWLLVVVVASDVGAFFGGKLLGKTPFTPTSP
NKTLEGALIGVVLASVLGSFVGMGKLSGGFFMALLFSFLIALMAVFGDLYESYLKRKVGIKDSGKILPGHGGVLDRLDSM
LFGALGLHALLYFLEIWKETAVFLGD

Sequences:

>Translated_266_residues
MKEELFKEKSRYITGFVLIIAAGLILYADNLLLFWAVLGGIYLVGFSEALRLFQVKASFSLYFILVLSWVAAYFNGRPIE
CALISAMVMASIIAYQKVHHSEAILPFLYPGVGFFALFGVYKDFGAVAIIWLLVVVVASDVGAFFGGKLLGKTPFTPTSP
NKTLEGALIGVVLASVLGSFVGMGKLSGGFFMALLFSFLIALMAVFGDLYESYLKRKVGIKDSGKILPGHGGVLDRLDSM
LFGALGLHALLYFLEIWKETAVFLGD
>Mature_266_residues
MKEELFKEKSRYITGFVLIIAAGLILYADNLLLFWAVLGGIYLVGFSEALRLFQVKASFSLYFILVLSWVAAYFNGRPIE
CALISAMVMASIIAYQKVHHSEAILPFLYPGVGFFALFGVYKDFGAVAIIWLLVVVVASDVGAFFGGKLLGKTPFTPTSP
NKTLEGALIGVVLASVLGSFVGMGKLSGGFFMALLFSFLIALMAVFGDLYESYLKRKVGIKDSGKILPGHGGVLDRLDSM
LFGALGLHALLYFLEIWKETAVFLGD

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=144, Percent_Identity=40.2777777777778, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787677, Length=108, Percent_Identity=40.7407407407407, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 28930; Mature: 28930

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]