Click here to switch to the map view.

The map label for this gene is hrcA [H]

Identifier: 108562536

GI number: 108562536

Start: 116344

End: 117174

Strand: Reverse

Name: hrcA [H]

Synonym: HPAG1_0111

Alternate gene names: 108562536

Gene position: 117174-116344 (Counterclockwise)

Preceding gene: 108562539

Following gene: 108562535

Centisome position: 7.34

GC content: 38.75

Gene sequence:

>831_bases
ATGGTGATTGACGAGATTTTTCAAATAATGATGTTAAGAAGAATTAAAGTAGGTTCTAATTTGAATAAAAAAGAGAGTTT
GTTAGATGCGTTTGTTAAAACCTATCTGCAGATTTTAGAACCCATTAGCTCTAAACGCTTGAAAGAGTTGGCAAACTTGA
AAATATCTTGCGCGACGATCAGGAATTATTTTCAAATCCTTTCTAAAGAAGGCATGCTCCATCAAGCCCATTCTAGCGGT
GCTAGATTGCCCACTTTTAAGGCGTTTGAAAACTATTGGCACAAGTCGTTGCGCTTTGAAGTTTTAAAGGTGAATGAAAA
ACGCTTAAAAAGCGCGAGTGAAAATTTTGGGCTTTTCACGCTGTTAAAAAAACCCAGTTTGGAGCGTTTAGAAAGAGTCA
TTGAGTGCGAAAAACGCTTTTTGATTTTGGATTTTTTGGCGTTTTCTTGCGCGCTGGGTTACAGCGTTAAAATGGAGAAG
TTTTTATTGGAGCTTGTGGGCAAAAGCGTTAAAGAAGTGCGCTCCATCGCTACTTCTGTCAATGCGTTGAGTTTGGCCAG
GCAATTAGAGCGTTTGGAGTATTCCAGTGCACAAATGACACGCTTTAATCTGATGGGGTTAAAAACGCTTTTAAACAGCC
CTTTATTTTTTGACATTTTAGAGGGTAAGGTTTTGGAGCGTTTCAAAAAGGGGTTGCATTTTATAGAGCCTGATTGCATG
CTGGTAATACGCCCCATAGAATTTCAAAACAAGCGGATACAACTGCTTTGCGTGGGGAAATTAGAATGCGATTATGAAGG
GTTTTTTCAAACGATTTCTGAGGAGGAATAA

Upstream 100 bases:

>100_bases
TAAACTTTAAAGAAAAATCGGGTAATTTTTATCACTTTTTTAAAACAAGTGATAGATTATTAACTTTTTGCGCTATAATG
CGAGGGTTCTTTCATCAAGA

Downstream 100 bases:

>100_bases
TGAAAGATGAACACAACCAAGAACACGATCATTTAAGCCAAAAAGAGCCAGAGTCTTATCAAAAGGCTTGCGCTTGCAAA
GAACAACAGGGTGAAGAAAA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATIRNYFQILSKEGMLHQAHSSG
ARLPTFKAFENYWHKSLRFEVLKVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEK
FLLELVGKSVKEVRSIATSVNALSLARQLERLEYSSAQMTRFNLMGLKTLLNSPLFFDILEGKVLERFKKGLHFIEPDCM
LVIRPIEFQNKRIQLLCVGKLECDYEGFFQTISEEE

Sequences:

>Translated_276_residues
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATIRNYFQILSKEGMLHQAHSSG
ARLPTFKAFENYWHKSLRFEVLKVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEK
FLLELVGKSVKEVRSIATSVNALSLARQLERLEYSSAQMTRFNLMGLKTLLNSPLFFDILEGKVLERFKKGLHFIEPDCM
LVIRPIEFQNKRIQLLCVGKLECDYEGFFQTISEEE
>Mature_276_residues
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATIRNYFQILSKEGMLHQAHSSG
ARLPTFKAFENYWHKSLRFEVLKVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEK
FLLELVGKSVKEVRSIATSVNALSLARQLERLEYSSAQMTRFNLMGLKTLLNSPLFFDILEGKVLERFKKGLHFIEPDCM
LVIRPIEFQNKRIQLLCVGKLECDYEGFFQTISEEE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32066; Mature: 32066

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATI
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RNYFQILSKEGMLHQAHSSGARLPTFKAFENYWHKSLRFEVLKVNEKRLKSASENFGLFT
HHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHCCCCCCEEE
LLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEKFLLELVGKSVKEVRSIATSV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NALSLARQLERLEYSSAQMTRFNLMGLKTLLNSPLFFDILEGKVLERFKKGLHFIEPDCM
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEECCCCE
LVIRPIEFQNKRIQLLCVGKLECDYEGFFQTISEEE
EEEECCCCCCCEEEEEEEECCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATI
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RNYFQILSKEGMLHQAHSSGARLPTFKAFENYWHKSLRFEVLKVNEKRLKSASENFGLFT
HHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHCCCCCCEEE
LLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEKFLLELVGKSVKEVRSIATSV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NALSLARQLERLEYSSAQMTRFNLMGLKTLLNSPLFFDILEGKVLERFKKGLHFIEPDCM
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEECCCCE
LVIRPIEFQNKRIQLLCVGKLECDYEGFFQTISEEE
EEEECCCCCCCEEEEEEEECCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]