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The map label for this gene is fabD [H]

Identifier: 108562516

GI number: 108562516

Start: 93372

End: 94301

Strand: Reverse

Name: fabD [H]

Synonym: HPAG1_0091

Alternate gene names: 108562516

Gene position: 94301-93372 (Counterclockwise)

Preceding gene: 108562519

Following gene: 108562515

Centisome position: 5.91

GC content: 43.01

Gene sequence:

>930_bases
ATGCAATACGCGCTATTATTTCCAGGGCAAGGCTCGCAATGTATAGGAATGGGAAAGTCATTCTATGAGAGCCACACCCT
AGCTAAAGAATTGTTTGAAAGGGCTTCTAACGCGCTTAAAGTGGATATGAAAAAAACGCTTTTTGAAGAAAACGAGCTTT
TAAAAGAGAGCGCTTACACCCAGCCTGCCATTTATTTAGTGAGCTATATCGCTTACCAATTGCTCAACAAGCAAGTGAAT
GGAGGGTTAAAACCCGTTTTTGCTTTAGGGCATTCGCTCGGCGAAGTGAGCGCGGTGTCTTTGAGCGGGGCGTTAGATTT
TGAAAAAGCCCTTAAACTCACGCACCAAAGAGGCAAAATGATGCAAGAAGCGTGCGCGAATAAAGACGCTTCCATGATGG
TCGTTTTGGGCGTTTCTGAAGAGAGTCTTTTGAGTTTGTGTCAAAGAACCAAAAATGTGTGGTGCGCGAATTTCAATGGC
GGCTTGCAAGTGGTTTTAGCCGGGATTAAAGACGATTTGAAAGCCCTAGAGCCGACTTTAAAGGAAATGGGGGCTAAAAG
AGTGGTTTTTTTAGAAATGAGCGTGGCGAGCCATTGCCCTTTTTTAGAGCCTATGATTTTTAAATTCCAGGAATTGCTAG
AAAAAAGCCTGAAAGATAAATTCCATTTTGAAATCATCTCCAATGCGACTAACGAAGCGTATCACAACAAAGCAAAAGCC
GTTGAACTATTGAGCTTGCAACTCACTCAGCCGGTGCGTTATCAAGACTGCGTGAAATCCAACAATGACCGAGTGGATGT
CTTTTTTGAATTAGGCTGTGGGAGTGTGTTAAAAGGGCTTAACAAGCGATTGAGCAACAAGCCTACTATAAGCGTGGGGG
ATAATAAAGGGCTTGATGAAGCGATTGAGTTTTTAGAAGAATACGTGTGA

Upstream 100 bases:

>100_bases
GTTAAAATAAACCTTAAACTTTAATGGTTTCTAAACAAAACTAAGGGCTTTTATATTACAATTTTAAATTATGGATTAAT
AAAATTTAAAGGATAACACC

Downstream 100 bases:

>100_bases
TGGGGAAAAAATGGTGCAAAAAATTGGCATTTTAGGAGCGATGAGAGAAGAAATAACCCCTATACTAGAATTGTTTGGTG
CGGGTTTTGAAGAGATCCCT

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MQYALLFPGQGSQCIGMGKSFYESHTLAKELFERASNALKVDMKKTLFEENELLKESAYTQPAIYLVSYIAYQLLNKQVN
GGLKPVFALGHSLGEVSAVSLSGALDFEKALKLTHQRGKMMQEACANKDASMMVVLGVSEESLLSLCQRTKNVWCANFNG
GLQVVLAGIKDDLKALEPTLKEMGAKRVVFLEMSVASHCPFLEPMIFKFQELLEKSLKDKFHFEIISNATNEAYHNKAKA
VELLSLQLTQPVRYQDCVKSNNDRVDVFFELGCGSVLKGLNKRLSNKPTISVGDNKGLDEAIEFLEEYV

Sequences:

>Translated_309_residues
MQYALLFPGQGSQCIGMGKSFYESHTLAKELFERASNALKVDMKKTLFEENELLKESAYTQPAIYLVSYIAYQLLNKQVN
GGLKPVFALGHSLGEVSAVSLSGALDFEKALKLTHQRGKMMQEACANKDASMMVVLGVSEESLLSLCQRTKNVWCANFNG
GLQVVLAGIKDDLKALEPTLKEMGAKRVVFLEMSVASHCPFLEPMIFKFQELLEKSLKDKFHFEIISNATNEAYHNKAKA
VELLSLQLTQPVRYQDCVKSNNDRVDVFFELGCGSVLKGLNKRLSNKPTISVGDNKGLDEAIEFLEEYV
>Mature_309_residues
MQYALLFPGQGSQCIGMGKSFYESHTLAKELFERASNALKVDMKKTLFEENELLKESAYTQPAIYLVSYIAYQLLNKQVN
GGLKPVFALGHSLGEVSAVSLSGALDFEKALKLTHQRGKMMQEACANKDASMMVVLGVSEESLLSLCQRTKNVWCANFNG
GLQVVLAGIKDDLKALEPTLKEMGAKRVVFLEMSVASHCPFLEPMIFKFQELLEKSLKDKFHFEIISNATNEAYHNKAKA
VELLSLQLTQPVRYQDCVKSNNDRVDVFFELGCGSVLKGLNKRLSNKPTISVGDNKGLDEAIEFLEEYV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=27.3026315789474, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1787334, Length=295, Percent_Identity=34.2372881355932, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17550940, Length=290, Percent_Identity=26.8965517241379, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71984332, Length=300, Percent_Identity=25.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665753, Length=288, Percent_Identity=29.1666666666667, Blast_Score=104, Evalue=9e-23,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34397; Mature: 34397

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYALLFPGQGSQCIGMGKSFYESHTLAKELFERASNALKVDMKKTLFEENELLKESAYT
CCEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCC
QPAIYLVSYIAYQLLNKQVNGGLKPVFALGHSLGEVSAVSLSGALDFEKALKLTHQRGKM
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHH
MQEACANKDASMMVVLGVSEESLLSLCQRTKNVWCANFNGGLQVVLAGIKDDLKALEPTL
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCEEEECCCCHHHEEHHHHHHHHHHHHHH
KEMGAKRVVFLEMSVASHCPFLEPMIFKFQELLEKSLKDKFHFEIISNATNEAYHNKAKA
HHCCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VELLSLQLTQPVRYQDCVKSNNDRVDVFFELGCGSVLKGLNKRLSNKPTISVGDNKGLDE
HHHHHHHHCCCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCHHH
AIEFLEEYV
HHHHHHHCC
>Mature Secondary Structure
MQYALLFPGQGSQCIGMGKSFYESHTLAKELFERASNALKVDMKKTLFEENELLKESAYT
CCEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCC
QPAIYLVSYIAYQLLNKQVNGGLKPVFALGHSLGEVSAVSLSGALDFEKALKLTHQRGKM
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHH
MQEACANKDASMMVVLGVSEESLLSLCQRTKNVWCANFNGGLQVVLAGIKDDLKALEPTL
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCEEEECCCCHHHEEHHHHHHHHHHHHHH
KEMGAKRVVFLEMSVASHCPFLEPMIFKFQELLEKSLKDKFHFEIISNATNEAYHNKAKA
HHCCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VELLSLQLTQPVRYQDCVKSNNDRVDVFFELGCGSVLKGLNKRLSNKPTISVGDNKGLDE
HHHHHHHHCCCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCHHH
AIEFLEEYV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]