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The map label for this gene is mtnN [H]

Identifier: 108562515

GI number: 108562515

Start: 92666

End: 93361

Strand: Reverse

Name: mtnN [H]

Synonym: HPAG1_0090

Alternate gene names: 108562515

Gene position: 93361-92666 (Counterclockwise)

Preceding gene: 108562516

Following gene: 108562514

Centisome position: 5.85

GC content: 42.82

Gene sequence:

>696_bases
ATGGTGCAAAAAATTGGCATTTTAGGAGCGATGAGAGAAGAAATAACCCCTATACTAGAATTGTTTGGTGCGGGTTTTGA
AGAGATCCCTTTAGGGGGGAATGTTTTCCATAAAGGCGTTTATTGCAACAAGGAAATCATTGTCGCTTATAGCAAGATTG
GCAAGGTGCATTCCACTTTAACCACAACGAGCATGATTTTAGCGTTTGGCGTTCAAAAAGTGCTTTTTAGCGGGGTGGCT
GGAAGCTTAGTTAAAGATTTAAAAATCAATGATTTGTTAGTGGCCAACCAATTAGTCCAGCATGATGTGGATTTGAGCGC
GTTTGATCACCCTTTAGGGTTTATCCCAGAAAGTGCGATTTTTATTGAAACGAGTGAAAGTTTGAACGCTTTAGCTAAAA
AAGTCGCTAATGAGCAGCATATCGCGCTCAAAGAAGGCGTCATCGCATCAGGCGATCAGTTTGTGCATAGCAAAGAAAGG
AAAGAGTTTTTAGTTAGCGAGTTCAAAGCGAGCGCGGTGGAAATGGAGGGGGCGAGCGTGGCGTTTGTGTGCCAAAAATT
TGGCGTGCCATGCTGCGTGCTAAGGAGCATTAGCGATAACGCTGACGAGGAAGCTAACATGAGCTTTGATGCGTTTTTAG
AAAAAAGCGCTCAAACTTCAGCGAAATTCTTAAAAAGCATGGTGGATAAGCTTTAG

Upstream 100 bases:

>100_bases
AACAAGCGATTGAGCAACAAGCCTACTATAAGCGTGGGGGATAATAAAGGGCTTGATGAAGCGATTGAGTTTTTAGAAGA
ATACGTGTGATGGGGAAAAA

Downstream 100 bases:

>100_bases
GGCTTGTTTTTATAGAGTTATGGAATGGAGTGGTGGAATGTAAAAAAGCTTTTTAGTATTTTTTACATTTTGTGATGAAT
ATTTAATAAAGTGGGGAAAA

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MVQKIGILGAMREEITPILELFGAGFEEIPLGGNVFHKGVYCNKEIIVAYSKIGKVHSTLTTTSMILAFGVQKVLFSGVA
GSLVKDLKINDLLVANQLVQHDVDLSAFDHPLGFIPESAIFIETSESLNALAKKVANEQHIALKEGVIASGDQFVHSKER
KEFLVSEFKASAVEMEGASVAFVCQKFGVPCCVLRSISDNADEEANMSFDAFLEKSAQTSAKFLKSMVDKL

Sequences:

>Translated_231_residues
MVQKIGILGAMREEITPILELFGAGFEEIPLGGNVFHKGVYCNKEIIVAYSKIGKVHSTLTTTSMILAFGVQKVLFSGVA
GSLVKDLKINDLLVANQLVQHDVDLSAFDHPLGFIPESAIFIETSESLNALAKKVANEQHIALKEGVIASGDQFVHSKER
KEFLVSEFKASAVEMEGASVAFVCQKFGVPCCVLRSISDNADEEANMSFDAFLEKSAQTSAKFLKSMVDKL
>Mature_231_residues
MVQKIGILGAMREEITPILELFGAGFEEIPLGGNVFHKGVYCNKEIIVAYSKIGKVHSTLTTTSMILAFGVQKVLFSGVA
GSLVKDLKINDLLVANQLVQHDVDLSAFDHPLGFIPESAIFIETSESLNALAKKVANEQHIALKEGVIASGDQFVHSKER
KEFLVSEFKASAVEMEGASVAFVCQKFGVPCCVLRSISDNADEEANMSFDAFLEKSAQTSAKFLKSMVDKL

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=233, Percent_Identity=34.7639484978541, Blast_Score=114, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 25060; Mature: 25060

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQKIGILGAMREEITPILELFGAGFEEIPLGGNVFHKGVYCNKEIIVAYSKIGKVHSTL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHCCEEECCHHEEHHHHHHHHHHHH
TTTSMILAFGVQKVLFSGVAGSLVKDLKINDLLVANQLVQHDVDLSAFDHPLGFIPESAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEE
FIETSESLNALAKKVANEQHIALKEGVIASGDQFVHSKERKEFLVSEFKASAVEMEGASV
EEECHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AFVCQKFGVPCCVLRSISDNADEEANMSFDAFLEKSAQTSAKFLKSMVDKL
HHHHHHHCCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVQKIGILGAMREEITPILELFGAGFEEIPLGGNVFHKGVYCNKEIIVAYSKIGKVHSTL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHCCEEECCHHEEHHHHHHHHHHHH
TTTSMILAFGVQKVLFSGVAGSLVKDLKINDLLVANQLVQHDVDLSAFDHPLGFIPESAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEE
FIETSESLNALAKKVANEQHIALKEGVIASGDQFVHSKERKEFLVSEFKASAVEMEGASV
EEECHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AFVCQKFGVPCCVLRSISDNADEEANMSFDAFLEKSAQTSAKFLKSMVDKL
HHHHHHHCCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]