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The map label for this gene is cdd [H]

Identifier: 107023141

GI number: 107023141

Start: 1764094

End: 1764483

Strand: Reverse

Name: cdd [H]

Synonym: Bcen_1590

Alternate gene names: 107023141

Gene position: 1764483-1764094 (Counterclockwise)

Preceding gene: 107023142

Following gene: 107023135

Centisome position: 53.56

GC content: 67.69

Gene sequence:

>390_bases
ATGGAACGAGACGAACTGATCGAACAGGCGAAGGCGGCGCGCGAACGCGCGTATGCGCCGTATTCGCGCTTCAAGGTCGG
CGCGGCGCTGCTGGCGCGCGACGGGACGGTCTTCCACGGCTGCAACGTCGAGAACGCGTCGTACGGCCTGTGCAATTGCG
CGGAACGCACGGCGCTGTTCGCGGCGATCGCCGCCGGCTATCGGCCCGGGGATTTCGCGCGGCTCGCGGTGGTGGGCGAC
ACGGACGGACCGATCGCGCCGTGCGGCGCATGTCGTCAGGTGATCATCGAGATCGGCAAGCCCGACATCGAAGTGATCCT
CACGAACCTGAAAGGGGCCGTCGAGATCACGACGGCCCGCGCATTGCTGCCGGGCGCGTTCACGCTGTAG

Upstream 100 bases:

>100_bases
GATGCGATCCGCCGCGGCTACGTGCTCGGCGAGACCGGCGAAGCGCCGCCGACCCTTTACCAGCGCGTCGACTGACCGCG
CTCCCGGAGGCTTCACCACG

Downstream 100 bases:

>100_bases
CGGCGCGCGCCGCGGCGCGCCGCGCGTTACGCGCTGTCGCGCACGTCGCGAATCGGGATCACGGTGCGCGCGCCGCACTG
GCGCAGCAGGTCGCGCAGCT

Product: cytidine deaminase, homotetrameric

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MERDELIEQAKAARERAYAPYSRFKVGAALLARDGTVFHGCNVENASYGLCNCAERTALFAAIAAGYRPGDFARLAVVGD
TDGPIAPCGACRQVIIEIGKPDIEVILTNLKGAVEITTARALLPGAFTL

Sequences:

>Translated_129_residues
MERDELIEQAKAARERAYAPYSRFKVGAALLARDGTVFHGCNVENASYGLCNCAERTALFAAIAAGYRPGDFARLAVVGD
TDGPIAPCGACRQVIIEIGKPDIEVILTNLKGAVEITTARALLPGAFTL
>Mature_129_residues
MERDELIEQAKAARERAYAPYSRFKVGAALLARDGTVFHGCNVENASYGLCNCAERTALFAAIAAGYRPGDFARLAVVGD
TDGPIAPCGACRQVIIEIGKPDIEVILTNLKGAVEITTARALLPGAFTL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=125, Percent_Identity=45.6, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17540514, Length=124, Percent_Identity=49.1935483870968, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17551074, Length=127, Percent_Identity=45.6692913385827, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323274, Length=128, Percent_Identity=39.84375, Blast_Score=97, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24582741, Length=131, Percent_Identity=46.5648854961832, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24582744, Length=139, Percent_Identity=40.2877697841727, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920920, Length=106, Percent_Identity=45.2830188679245, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13671; Mature: 13671

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERDELIEQAKAARERAYAPYSRFKVGAALLARDGTVFHGCNVENASYGLCNCAERTALF
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHH
AAIAAGYRPGDFARLAVVGDTDGPIAPCGACRQVIIEIGKPDIEVILTNLKGAVEITTAR
HHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHH
ALLPGAFTL
HHCCCCCCC
>Mature Secondary Structure
MERDELIEQAKAARERAYAPYSRFKVGAALLARDGTVFHGCNVENASYGLCNCAERTALF
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHH
AAIAAGYRPGDFARLAVVGDTDGPIAPCGACRQVIIEIGKPDIEVILTNLKGAVEITTAR
HHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHH
ALLPGAFTL
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]