Click here to switch to the map view.

The map label for this gene is deoR [H]

Identifier: 107023093

GI number: 107023093

Start: 1715290

End: 1716060

Strand: Reverse

Name: deoR [H]

Synonym: Bcen_1542

Alternate gene names: 107023093

Gene position: 1716060-1715290 (Counterclockwise)

Preceding gene: 107023097

Following gene: 107023089

Centisome position: 52.09

GC content: 60.83

Gene sequence:

>771_bases
ATGGAAACAAAGAAGGGCGAACGGATCAAGACATTGATGAACGTGCTGCAAGGGCAGAACGCGATTCATCTGAGGGAAGT
CGCCGAGTTGTTCGGCGTATCCGAAATGACGATCCGCCGCGATCTCGCGGACAATCCGCACGGCCTCAGCCTGATCGGCG
GCTACGTGACGCGCCATTTCGCCGCGCAGCGCAGCGACATCGGCGAATACCTGATCAGCGCCGAGAACAACCGGCAGACC
GAGGAAAAGCGCCGCATCGGCAAGCTGGCCGCGCAGTTCGTGACGACCGGCGACACGATCTTCGTCGACTGCGGGTCGAC
CACGCCGTTCATCGTCGATTTCATCCCCGACGACCTCGAATTCACGGCGGTCTGCAATTCGCTGAACGTGTTCGCGAAGC
TGCAGCAAAAGCCGCATTGCAACGTGATCCTGTGCGGCGGCGCGTATCACCGCCAGAACATGGTGTTCGAATCGGTCGCC
GAAACGGGCATCCTCGATTCGGTGCGCGTGTCGAAGGCGTTCATCTCGGCGGCCGGCGTGAGCGAACGCTGCGGCGTCAC
GTGCTTCAATTTCCACGAAGTCGATGCGAAGAAGAAGGTGATGGCGCGCGCGCAGAACCGCTTTCTGCTGGTCGACCACA
CGAAATTCGACGAGGTGCGCGCGGCCTATTTCGCCGAACTGACCGATTTCAACTACGTGATCTCCGACGGGCAACTGAGC
CGCCGCTACGAAACGACGATCCGCGAGCACGGGATCGCGCTCGTGACCTGA

Upstream 100 bases:

>100_bases
TGATGTTTTCACATCGGTTTGTTACAAATACGACATTCCGGCCGGGCCCGCGCGCCCGGCACGACGAGCGACTCACGCGG
CGGGCACGCAGGATACAGGC

Downstream 100 bases:

>100_bases
TGCGGCGCGGGCGTGCGGCGCGCGCTGCGTCGCACTTTTCGTCGCGCTTTTCATCACATCACGCATCGCGGGCTTCCGCC
GCGCTCAGGTAGCCGGTGAC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
METKKGERIKTLMNVLQGQNAIHLREVAELFGVSEMTIRRDLADNPHGLSLIGGYVTRHFAAQRSDIGEYLISAENNRQT
EEKRRIGKLAAQFVTTGDTIFVDCGSTTPFIVDFIPDDLEFTAVCNSLNVFAKLQQKPHCNVILCGGAYHRQNMVFESVA
ETGILDSVRVSKAFISAAGVSERCGVTCFNFHEVDAKKKVMARAQNRFLLVDHTKFDEVRAAYFAELTDFNYVISDGQLS
RRYETTIREHGIALVT

Sequences:

>Translated_256_residues
METKKGERIKTLMNVLQGQNAIHLREVAELFGVSEMTIRRDLADNPHGLSLIGGYVTRHFAAQRSDIGEYLISAENNRQT
EEKRRIGKLAAQFVTTGDTIFVDCGSTTPFIVDFIPDDLEFTAVCNSLNVFAKLQQKPHCNVILCGGAYHRQNMVFESVA
ETGILDSVRVSKAFISAAGVSERCGVTCFNFHEVDAKKKVMARAQNRFLLVDHTKFDEVRAAYFAELTDFNYVISDGQLS
RRYETTIREHGIALVT
>Mature_256_residues
METKKGERIKTLMNVLQGQNAIHLREVAELFGVSEMTIRRDLADNPHGLSLIGGYVTRHFAAQRSDIGEYLISAENNRQT
EEKRRIGKLAAQFVTTGDTIFVDCGSTTPFIVDFIPDDLEFTAVCNSLNVFAKLQQKPHCNVILCGGAYHRQNMVFESVA
ETGILDSVRVSKAFISAAGVSERCGVTCFNFHEVDAKKKVMARAQNRFLLVDHTKFDEVRAAYFAELTDFNYVISDGQLS
RRYETTIREHGIALVT

Specific function: This protein is one of the repressors that regulate the expression of deoCABD genes, which encode nucleotide and deoxy ribonucleotide catabolizing enzymes. It also negatively regulates the expression of nupG (a transport protein) and tsx (a pore- forming

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787063, Length=236, Percent_Identity=44.0677966101695, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1790753, Length=252, Percent_Identity=28.968253968254, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI226510968, Length=257, Percent_Identity=26.4591439688716, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789829, Length=253, Percent_Identity=24.901185770751, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=26.6094420600858, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=25.5905511811024, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082344, Length=237, Percent_Identity=24.8945147679325, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788069, Length=259, Percent_Identity=25.0965250965251, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=20.8661417322835, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=23.0769230769231, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28675; Mature: 28675

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKKGERIKTLMNVLQGQNAIHLREVAELFGVSEMTIRRDLADNPHGLSLIGGYVTRHF
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
AAQRSDIGEYLISAENNRQTEEKRRIGKLAAQFVTTGDTIFVDCGSTTPFIVDFIPDDLE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCH
FTAVCNSLNVFAKLQQKPHCNVILCGGAYHRQNMVFESVAETGILDSVRVSKAFISAAGV
HHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SERCGVTCFNFHEVDAKKKVMARAQNRFLLVDHTKFDEVRAAYFAELTDFNYVISDGQLS
CCCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCHH
RRYETTIREHGIALVT
HHHHHHHHHCCEEEEC
>Mature Secondary Structure
METKKGERIKTLMNVLQGQNAIHLREVAELFGVSEMTIRRDLADNPHGLSLIGGYVTRHF
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
AAQRSDIGEYLISAENNRQTEEKRRIGKLAAQFVTTGDTIFVDCGSTTPFIVDFIPDDLE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCH
FTAVCNSLNVFAKLQQKPHCNVILCGGAYHRQNMVFESVAETGILDSVRVSKAFISAAGV
HHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SERCGVTCFNFHEVDAKKKVMARAQNRFLLVDHTKFDEVRAAYFAELTDFNYVISDGQLS
CCCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCHH
RRYETTIREHGIALVT
HHHHHHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]