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The map label for this gene is puuP [H]

Identifier: 107023080

GI number: 107023080

Start: 1700664

End: 1702085

Strand: Reverse

Name: puuP [H]

Synonym: Bcen_1529

Alternate gene names: 107023080

Gene position: 1702085-1700664 (Counterclockwise)

Preceding gene: 107023081

Following gene: 107023079

Centisome position: 51.66

GC content: 57.03

Gene sequence:

>1422_bases
ATGGATACTCATATTTCGCGCGGATCTGGAAGTCAGGCCGCTATTTCGTCAGCAGGGTTCGCCGGTGCGAATCCGTCTGA
ACAAACTGCCGGAATAAGCGAATCGTCCTTGAAATTGAGCCGCGAATTGAGTGTGCTCGATTTGATCGTGTACGGCATGG
TTTACATGCTTCCGATCGCGCCGTTCGCACTTTACGGAATCATTTCCAATGTCAGCGGCGGTATGGTGCCGCTGGTATAC
ATCGTGAGTGTCGTCGCGATGATGTTTACGGCCCGGAGTTACCAGATACTCAGCAAGGAATTTCCGGCAGCCGGGTCAGC
CTATACCTATGCTCAAAACGGCATCGGCGATCTGGCCGGTTTTCTGGCCGGATGGCTGGTGTTTCTCGACTACATCATCG
CGCCGGGACTGCTCGCGGTCGTCAGCGCGGTTGCGATGAACAGCCTGGTGCCCGAGATTCCCCGTTCCGTCTGGGTGATC
GGATTCGTCGGCCTCGGAACGATCCTGAATCTGGTCGGTATCTCGGTGACCGCGAAAGTGAACCAGGCGTTCCTCGTGAT
CATGCTGGTCATTCTGGCCGCGTTCGTCGGAGTCGGTCTCTTTGCGCTTTACAGCGGCATGGGGCACGGCCGGCTCACGT
TCGGTTCGCTCTTCAATGTCCATACTTTCACATGGGCGGGGCTCGGCACCGGCATCCTCATCGGTTCGACGAACTTTCTC
GGCTTCGACGCGATCACGACGCTCGGAGAAGAAGTCAGGAGCGAGAAGCGTCATCTGGCCAGCTTTGCCGGCATGGCATC
GCTGGTCATCATCGCGATCCTGTTCGTGCTGCAGACCTGGATTGCTGCCGACCTCGCGTCTGGCGCGAAGGTACTGTCGC
CGGATAGCGCCTTTTACGACATATCGGGTTACGCGGGCGGCCACTGGCTGTTCGCGATGACGTCCATCAGCACTGCACTG
GCATTCGGCGTGCCGTGCACGATCGTCTGCCAGATGGCAATCGCCCGCATCATCTTCGCGATGGGGCGCGACCGGCAGCT
TCCCAAGGTGTTTTCCCGTCTGTCGCGCAGATCGAAGCAACCGTATGTGGCGAATATTTTCGTTGCATCCATCTCGCTGA
TCATCGCATTGGTCTTTCAGGATCGGCTCGACGACCTGGCCTTGTTCCAGAACTTCGGCGCATTCTCTGCATTCATCCTG
GTCAACCTTTCCGTCATCGGTTACTTCAGGATCAAGAAGCAGTCGAAGGACACATGGAATCACGTGGTTCTGCCGGCGAT
CGGATTTCTCGTCATCGTTGCACTCATGGTCGCGATGAGGGCCGCAACGTTGAAGATGGGCATCATCTGGCTCGTGATCG
GGCTCGTCTATTACTTTGTGATGCGCCATGTGTTTGGACGCAGTGCGGCACTGAAGATCTGA

Upstream 100 bases:

>100_bases
TACGTATAAGTCAATGTTCAGTCTCATGGTCGGCTCAGGGCGACTGTCGGAGGCTGGATTCCGATCATGCCTCGAGCAAC
GAAGTGGAAGGACGTCTGGA

Downstream 100 bases:

>100_bases
GAACGACATCGATGATTCCGTTGCTCACGAGGAATTTTCGCTTGCAGGCTTGATGTGCGATGACTCGACGCCGGCCCTTC
GCGATGAAGGGCTCGTCGGG

Product: amino acid permease-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MDTHISRGSGSQAAISSAGFAGANPSEQTAGISESSLKLSRELSVLDLIVYGMVYMLPIAPFALYGIISNVSGGMVPLVY
IVSVVAMMFTARSYQILSKEFPAAGSAYTYAQNGIGDLAGFLAGWLVFLDYIIAPGLLAVVSAVAMNSLVPEIPRSVWVI
GFVGLGTILNLVGISVTAKVNQAFLVIMLVILAAFVGVGLFALYSGMGHGRLTFGSLFNVHTFTWAGLGTGILIGSTNFL
GFDAITTLGEEVRSEKRHLASFAGMASLVIIAILFVLQTWIAADLASGAKVLSPDSAFYDISGYAGGHWLFAMTSISTAL
AFGVPCTIVCQMAIARIIFAMGRDRQLPKVFSRLSRRSKQPYVANIFVASISLIIALVFQDRLDDLALFQNFGAFSAFIL
VNLSVIGYFRIKKQSKDTWNHVVLPAIGFLVIVALMVAMRAATLKMGIIWLVIGLVYYFVMRHVFGRSAALKI

Sequences:

>Translated_473_residues
MDTHISRGSGSQAAISSAGFAGANPSEQTAGISESSLKLSRELSVLDLIVYGMVYMLPIAPFALYGIISNVSGGMVPLVY
IVSVVAMMFTARSYQILSKEFPAAGSAYTYAQNGIGDLAGFLAGWLVFLDYIIAPGLLAVVSAVAMNSLVPEIPRSVWVI
GFVGLGTILNLVGISVTAKVNQAFLVIMLVILAAFVGVGLFALYSGMGHGRLTFGSLFNVHTFTWAGLGTGILIGSTNFL
GFDAITTLGEEVRSEKRHLASFAGMASLVIIAILFVLQTWIAADLASGAKVLSPDSAFYDISGYAGGHWLFAMTSISTAL
AFGVPCTIVCQMAIARIIFAMGRDRQLPKVFSRLSRRSKQPYVANIFVASISLIIALVFQDRLDDLALFQNFGAFSAFIL
VNLSVIGYFRIKKQSKDTWNHVVLPAIGFLVIVALMVAMRAATLKMGIIWLVIGLVYYFVMRHVFGRSAALKI
>Mature_473_residues
MDTHISRGSGSQAAISSAGFAGANPSEQTAGISESSLKLSRELSVLDLIVYGMVYMLPIAPFALYGIISNVSGGMVPLVY
IVSVVAMMFTARSYQILSKEFPAAGSAYTYAQNGIGDLAGFLAGWLVFLDYIIAPGLLAVVSAVAMNSLVPEIPRSVWVI
GFVGLGTILNLVGISVTAKVNQAFLVIMLVILAAFVGVGLFALYSGMGHGRLTFGSLFNVHTFTWAGLGTGILIGSTNFL
GFDAITTLGEEVRSEKRHLASFAGMASLVIIAILFVLQTWIAADLASGAKVLSPDSAFYDISGYAGGHWLFAMTSISTAL
AFGVPCTIVCQMAIARIIFAMGRDRQLPKVFSRLSRRSKQPYVANIFVASISLIIALVFQDRLDDLALFQNFGAFSAFIL
VNLSVIGYFRIKKQSKDTWNHVVLPAIGFLVIVALMVAMRAATLKMGIIWLVIGLVYYFVMRHVFGRSAALKI

Specific function: Imports putrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=423, Percent_Identity=23.6406619385343, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI114326544, Length=435, Percent_Identity=24.367816091954, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI114326550, Length=435, Percent_Identity=24.367816091954, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI87081869, Length=437, Percent_Identity=30.8924485125858, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI87082023, Length=440, Percent_Identity=31.8181818181818, Blast_Score=191, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17533459, Length=401, Percent_Identity=28.428927680798, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17532491, Length=414, Percent_Identity=24.6376811594203, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17531343, Length=414, Percent_Identity=23.4299516908213, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24668806, Length=407, Percent_Identity=24.0786240786241, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21356285, Length=407, Percent_Identity=24.0786240786241, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24668802, Length=407, Percent_Identity=24.0786240786241, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI221512776, Length=418, Percent_Identity=26.555023923445, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666159, Length=413, Percent_Identity=26.634382566586, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50643; Mature: 50643

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]