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The map label for this gene is clpB [H]

Identifier: 107022970

GI number: 107022970

Start: 1569218

End: 1571041

Strand: Reverse

Name: clpB [H]

Synonym: Bcen_1418

Alternate gene names: 107022970

Gene position: 1571041-1569218 (Counterclockwise)

Preceding gene: 107022971

Following gene: 107022969

Centisome position: 47.69

GC content: 60.91

Gene sequence:

>1824_bases
ATGCCTGCATACGTCAAACCAAGATGGTTAAGGGATCTGCTGCGTTTCCTCCCTTTGAAGAGCCAGTTCGTGCTATCGGG
AAACGTGCGCGACTTGCAGGCCGGTGAGATTGCACCTGAAGTCGTGACGGCGCAGTCGCTGGTCAATACGTTGGGCGACA
ATCTCCGGGAAGCAGGCTACGCGCAGTTGATTGTCTGGAATCCGGTTTCAGGTTTTACGGTGCCGGAAAGCCGGTTGCCG
CCGACGGAGCCTGCCGACGATACCTTGCGGCGCCTGGGCCTGACACCGGTCGACGGCGCAGCGCCCGGCGGCATCGATGC
GCTGACTGCGTGCCTCGATCGCCTTGCCGCGCTGCCGGGCTTGCCGGTTGCGCTCGTCGTCGATTTCGCTTCCCGGCTCG
CGATTCGCGCGGAAGCGCTGAATCCGGCCGAGCACGCACTTTTCACGCGGGCGCTGGTATTGGCGCATACGGCGGCACCG
CGCCCGGCGGGAGAATTACGACGTCCGTTTTTCAATACCGTGATTTGGATCGTCGACAAGGAGGGCGATTTGCCCGACTG
GTTGCTGGTCGACAATCCGCGTATTCGGCACATTCCCGTATCCAGACCCGATAGTGCCGCCCGTCGCGCATTGGCCGGCG
CGCTGCTCCGTGGCGTATCCGGCGCTCCGGCCGCTACGCCGGACAGTCTTGCCCAGGCGGAAGCCGCATTCGTCGATGGT
TCCGAGGGATTGCTGCTTGCGGACATGAATGCGATCGCCACGCTCGCTCGAGTCGAGCAGGTTCCCGTCGAGAAGATTGC
TGATGCCGTGCGGCGCTACAAGGTTGGCGTCACCGAAGATCCATGGTTGCAGATTGATCGCGACAAAATTCGTCGGGCAG
ACACGTTTGTGCGGCAGCGGGTCAAGGGGCAGGTGCACGCGGTCACGCATATGCTCGACCTCGTCAAGCGCGCCATGACC
GGCGTGGGGTCCGGCCGCAAGGGAAACCGGCCGCGCGGCGTTGCATTCCTCGCCGGCCCGACCGGGGTCGGGAAAACCGA
ACTCGCCAAGACCATCACGAGTTTGCTGTTCGGCGACGAAAGCGCCTACATTCGTTTCGACATGTCGGAATTCAGCGCCG
AGCATGCCGACCAGCGACTGATCGGCGCGCCGCCGGGCTATGTTGGCTACGATGTCGGCGGCGAATTGACGAATGCGATT
CGCGAACGTCCGTTCAGTGTCGTGCTCTTCGATGAAATCGAAAAGGCGCATCCGCGCATCCTCGACAAGTTCCTGCAGAT
CCTCGACGACGGCGTATTGACATCGGGGCGTGGCGATCGCGTCTATTTTTCCGAGGCGCTGATTGTTTTTACGTCGAACC
TCGGCATCTACCGTCAGGACGAATCGGGTCTGCGTGTGACGAACGTCCAGCCGGGCGACGATTTTGCGGCGATTCAGAGC
AAAGTACTCGGGGAAATCCAGCGGCATTTCAAGCTGGTCCTGAACCGTCCCGAGATTCTCAACCGCATCGGCGAGAACAT
CATCGTCTTCGACTTCATCCGCGAGGATGTCGCGACGGATATCTTCGATCAGATGGTCGGTGCCGTGCTCGGCGATATCG
CGTCTCAGGGAATTGCCATCGATCTGGATGCGCGATCCAGGGAAGCACTTCGGGCAAGATGCCTCGCCGATCTATCCAAC
GGTGGCCGCGGCATTCGCAATCAGATCGAGGCACATCTGCTTAATCCGCTGGCACGCGGTTTGTTCGATCAGGATGCGAA
TCCCGGCGATCGGTTTGTCATCTCGGGCATTGACGCAGGCGCGTTGCAATTGCAGAAGCAATAG

Upstream 100 bases:

>100_bases
CCCGCTATTGGTTTTTCTGATATTGACATCCATTCGGGATATGCCGATGGACGGGCTATGGTAACGTTTTGCTTTCGTTT
TCCGCGCTCGCCATTACGAC

Downstream 100 bases:

>100_bases
TCCATGGACATCCGTATTTCGCGCCTTCATTTTCCCGTTACGACACTCGGACCGGGGCAGCGGATCGGAATCTGGTTTCA
GGGTTGCTCGATTCGATGCC

Product: ATPase AAA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MPAYVKPRWLRDLLRFLPLKSQFVLSGNVRDLQAGEIAPEVVTAQSLVNTLGDNLREAGYAQLIVWNPVSGFTVPESRLP
PTEPADDTLRRLGLTPVDGAAPGGIDALTACLDRLAALPGLPVALVVDFASRLAIRAEALNPAEHALFTRALVLAHTAAP
RPAGELRRPFFNTVIWIVDKEGDLPDWLLVDNPRIRHIPVSRPDSAARRALAGALLRGVSGAPAATPDSLAQAEAAFVDG
SEGLLLADMNAIATLARVEQVPVEKIADAVRRYKVGVTEDPWLQIDRDKIRRADTFVRQRVKGQVHAVTHMLDLVKRAMT
GVGSGRKGNRPRGVAFLAGPTGVGKTELAKTITSLLFGDESAYIRFDMSEFSAEHADQRLIGAPPGYVGYDVGGELTNAI
RERPFSVVLFDEIEKAHPRILDKFLQILDDGVLTSGRGDRVYFSEALIVFTSNLGIYRQDESGLRVTNVQPGDDFAAIQS
KVLGEIQRHFKLVLNRPEILNRIGENIIVFDFIREDVATDIFDQMVGAVLGDIASQGIAIDLDARSREALRARCLADLSN
GGRGIRNQIEAHLLNPLARGLFDQDANPGDRFVISGIDAGALQLQKQ

Sequences:

>Translated_607_residues
MPAYVKPRWLRDLLRFLPLKSQFVLSGNVRDLQAGEIAPEVVTAQSLVNTLGDNLREAGYAQLIVWNPVSGFTVPESRLP
PTEPADDTLRRLGLTPVDGAAPGGIDALTACLDRLAALPGLPVALVVDFASRLAIRAEALNPAEHALFTRALVLAHTAAP
RPAGELRRPFFNTVIWIVDKEGDLPDWLLVDNPRIRHIPVSRPDSAARRALAGALLRGVSGAPAATPDSLAQAEAAFVDG
SEGLLLADMNAIATLARVEQVPVEKIADAVRRYKVGVTEDPWLQIDRDKIRRADTFVRQRVKGQVHAVTHMLDLVKRAMT
GVGSGRKGNRPRGVAFLAGPTGVGKTELAKTITSLLFGDESAYIRFDMSEFSAEHADQRLIGAPPGYVGYDVGGELTNAI
RERPFSVVLFDEIEKAHPRILDKFLQILDDGVLTSGRGDRVYFSEALIVFTSNLGIYRQDESGLRVTNVQPGDDFAAIQS
KVLGEIQRHFKLVLNRPEILNRIGENIIVFDFIREDVATDIFDQMVGAVLGDIASQGIAIDLDARSREALRARCLADLSN
GGRGIRNQIEAHLLNPLARGLFDQDANPGDRFVISGIDAGALQLQKQ
>Mature_606_residues
PAYVKPRWLRDLLRFLPLKSQFVLSGNVRDLQAGEIAPEVVTAQSLVNTLGDNLREAGYAQLIVWNPVSGFTVPESRLPP
TEPADDTLRRLGLTPVDGAAPGGIDALTACLDRLAALPGLPVALVVDFASRLAIRAEALNPAEHALFTRALVLAHTAAPR
PAGELRRPFFNTVIWIVDKEGDLPDWLLVDNPRIRHIPVSRPDSAARRALAGALLRGVSGAPAATPDSLAQAEAAFVDGS
EGLLLADMNAIATLARVEQVPVEKIADAVRRYKVGVTEDPWLQIDRDKIRRADTFVRQRVKGQVHAVTHMLDLVKRAMTG
VGSGRKGNRPRGVAFLAGPTGVGKTELAKTITSLLFGDESAYIRFDMSEFSAEHADQRLIGAPPGYVGYDVGGELTNAIR
ERPFSVVLFDEIEKAHPRILDKFLQILDDGVLTSGRGDRVYFSEALIVFTSNLGIYRQDESGLRVTNVQPGDDFAAIQSK
VLGEIQRHFKLVLNRPEILNRIGENIIVFDFIREDVATDIFDQMVGAVLGDIASQGIAIDLDARSREALRARCLADLSNG
GRGIRNQIEAHLLNPLARGLFDQDANPGDRFVISGIDAGALQLQKQ

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=276, Percent_Identity=31.5217391304348, Blast_Score=131, Evalue=2e-30,
Organism=Escherichia coli, GI1788943, Length=327, Percent_Identity=36.697247706422, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1787109, Length=326, Percent_Identity=33.7423312883436, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320464, Length=311, Percent_Identity=36.9774919614148, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6323002, Length=328, Percent_Identity=32.9268292682927, Blast_Score=162, Evalue=1e-40,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 66015; Mature: 65884

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAYVKPRWLRDLLRFLPLKSQFVLSGNVRDLQAGEIAPEVVTAQSLVNTLGDNLREAGY
CCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
AQLIVWNPVSGFTVPESRLPPTEPADDTLRRLGLTPVDGAAPGGIDALTACLDRLAALPG
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
LPVALVVDFASRLAIRAEALNPAEHALFTRALVLAHTAAPRPAGELRRPFFNTVIWIVDK
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEEEEEEC
EGDLPDWLLVDNPRIRHIPVSRPDSAARRALAGALLRGVSGAPAATPDSLAQAEAAFVDG
CCCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEECC
SEGLLLADMNAIATLARVEQVPVEKIADAVRRYKVGVTEDPWLQIDRDKIRRADTFVRQR
CCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHH
VKGQVHAVTHMLDLVKRAMTGVGSGRKGNRPRGVAFLAGPTGVGKTELAKTITSLLFGDE
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
SAYIRFDMSEFSAEHADQRLIGAPPGYVGYDVGGELTNAIRERPFSVVLFDEIEKAHPRI
CCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHH
LDKFLQILDDGVLTSGRGDRVYFSEALIVFTSNLGIYRQDESGLRVTNVQPGDDFAAIQS
HHHHHHHHCCCCEECCCCCEEEEEEEEEEEECCCCEEEECCCCCEEEECCCCCHHHHHHH
KVLGEIQRHFKLVLNRPEILNRIGENIIVFDFIREDVATDIFDQMVGAVLGDIASQGIAI
HHHHHHHHHHHHHCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DLDARSREALRARCLADLSNGGRGIRNQIEAHLLNPLARGLFDQDANPGDRFVISGIDAG
EECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
ALQLQKQ
CCEEECC
>Mature Secondary Structure 
PAYVKPRWLRDLLRFLPLKSQFVLSGNVRDLQAGEIAPEVVTAQSLVNTLGDNLREAGY
CCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
AQLIVWNPVSGFTVPESRLPPTEPADDTLRRLGLTPVDGAAPGGIDALTACLDRLAALPG
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
LPVALVVDFASRLAIRAEALNPAEHALFTRALVLAHTAAPRPAGELRRPFFNTVIWIVDK
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEEEEEEC
EGDLPDWLLVDNPRIRHIPVSRPDSAARRALAGALLRGVSGAPAATPDSLAQAEAAFVDG
CCCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEECC
SEGLLLADMNAIATLARVEQVPVEKIADAVRRYKVGVTEDPWLQIDRDKIRRADTFVRQR
CCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHH
VKGQVHAVTHMLDLVKRAMTGVGSGRKGNRPRGVAFLAGPTGVGKTELAKTITSLLFGDE
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
SAYIRFDMSEFSAEHADQRLIGAPPGYVGYDVGGELTNAIRERPFSVVLFDEIEKAHPRI
CCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHH
LDKFLQILDDGVLTSGRGDRVYFSEALIVFTSNLGIYRQDESGLRVTNVQPGDDFAAIQS
HHHHHHHHCCCCEECCCCCEEEEEEEEEEEECCCCEEEECCCCCEEEECCCCCHHHHHHH
KVLGEIQRHFKLVLNRPEILNRIGENIIVFDFIREDVATDIFDQMVGAVLGDIASQGIAI
HHHHHHHHHHHHHCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DLDARSREALRARCLADLSNGGRGIRNQIEAHLLNPLARGLFDQDANPGDRFVISGIDAG
EECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
ALQLQKQ
CCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA