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The map label for this gene is gmhB [H]

Identifier: 107022937

GI number: 107022937

Start: 1523399

End: 1524010

Strand: Reverse

Name: gmhB [H]

Synonym: Bcen_1385

Alternate gene names: 107022937

Gene position: 1524010-1523399 (Counterclockwise)

Preceding gene: 107022938

Following gene: 107022936

Centisome position: 46.26

GC content: 71.9

Gene sequence:

>612_bases
ATGGCCCTGAAGCGCGAACGGCGGCTGCCCGGCGCGGTGCTGCTCGACAAGGACGGCACGCTGCTCGACGACGTGCCGTA
CAACGTCGACCCCGCGCGCATGCGCCTCGCGCCGGGCGCCGCGCGTGCGCTGCGCACGCTCGGCGCGACCGGCATGCCGC
TGGCGGTCGTGTCGAACCAGCCGGGCGTCGCGCTCGGCCGCTTTACCGAAAACGAGCTTGGCGCGGTCCGCCAGCGTCTC
GCCGAACTGTTCGAAGCAAACGGCGCGACGCTGGCGGATTTTTTTTACTGCCCGCATCACCCGCGGGGCAGCGTGCCGCG
CTACACCTGTGACTGCATCTGCCGCAAGCCGCGCCCGGGCATGCTGCGCCGCGCGCTGAGCGCGCTCGGTGCCGTGCCCG
AATGGAGCTGGATGATCGGCGACATTCTCGACGACGTCGAGGCCGGCCGCACCGCGCGCTGCGGCACGATCCTGGTCGAC
TGCGGCAACGAGACCGAGTGGCAGCTCAACGCCGCGCGCACGCCGCACCACGTCGTCGATCGCATCGACCTGGCCGCCGA
CATCGTGGTGCGCGAAGCCGTGCGCCGGCACGGCTCGTGGGTGCGGCGATGA

Upstream 100 bases:

>100_bases
AGCCGCCGGAGCACGTCGCGGCCGCCGTGCGCTTCGTGCTGACGCAGCCGCCGGGCACCGTGGTGCCGGAGCTGATGGTG
CTGCCGATGAAGGAGACGTC

Downstream 100 bases:

>100_bases
GCACGGCCTGGAGCCGCGCCCGCCGCATCCTGTGCGTGCGGCTCGACAGCATCGGCGACGTGCTGATGACCACGCCCGCG
CTGCGCGCGCTGAAGGAGAG

Product: histidinol-phosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MALKRERRLPGAVLLDKDGTLLDDVPYNVDPARMRLAPGAARALRTLGATGMPLAVVSNQPGVALGRFTENELGAVRQRL
AELFEANGATLADFFYCPHHPRGSVPRYTCDCICRKPRPGMLRRALSALGAVPEWSWMIGDILDDVEAGRTARCGTILVD
CGNETEWQLNAARTPHHVVDRIDLAADIVVREAVRRHGSWVRR

Sequences:

>Translated_203_residues
MALKRERRLPGAVLLDKDGTLLDDVPYNVDPARMRLAPGAARALRTLGATGMPLAVVSNQPGVALGRFTENELGAVRQRL
AELFEANGATLADFFYCPHHPRGSVPRYTCDCICRKPRPGMLRRALSALGAVPEWSWMIGDILDDVEAGRTARCGTILVD
CGNETEWQLNAARTPHHVVDRIDLAADIVVREAVRRHGSWVRR
>Mature_202_residues
ALKRERRLPGAVLLDKDGTLLDDVPYNVDPARMRLAPGAARALRTLGATGMPLAVVSNQPGVALGRFTENELGAVRQRLA
ELFEANGATLADFFYCPHHPRGSVPRYTCDCICRKPRPGMLRRALSALGAVPEWSWMIGDILDDVEAGRTARCGTILVDC
GNETEWQLNAARTPHHVVDRIDLAADIVVREAVRRHGSWVRR

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=169, Percent_Identity=36.6863905325444, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082027, Length=138, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 22372; Mature: 22241

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKRERRLPGAVLLDKDGTLLDDVPYNVDPARMRLAPGAARALRTLGATGMPLAVVSNQ
CCCCCCCCCCCEEEECCCCCEECCCCCCCCHHHEEECCHHHHHHHHHCCCCCCEEEECCC
PGVALGRFTENELGAVRQRLAELFEANGATLADFFYCPHHPRGSVPRYTCDCICRKPRPG
CCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEHHEEECCCCCH
MLRRALSALGAVPEWSWMIGDILDDVEAGRTARCGTILVDCGNETEWQLNAARTPHHVVD
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCHHHHHH
RIDLAADIVVREAVRRHGSWVRR
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALKRERRLPGAVLLDKDGTLLDDVPYNVDPARMRLAPGAARALRTLGATGMPLAVVSNQ
CCCCCCCCCCEEEECCCCCEECCCCCCCCHHHEEECCHHHHHHHHHCCCCCCEEEECCC
PGVALGRFTENELGAVRQRLAELFEANGATLADFFYCPHHPRGSVPRYTCDCICRKPRPG
CCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEHHEEECCCCCH
MLRRALSALGAVPEWSWMIGDILDDVEAGRTARCGTILVDCGNETEWQLNAARTPHHVVD
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCHHHHHH
RIDLAADIVVREAVRRHGSWVRR
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]