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The map label for this gene is atoC [H]

Identifier: 107022930

GI number: 107022930

Start: 1514650

End: 1516017

Strand: Reverse

Name: atoC [H]

Synonym: Bcen_1378

Alternate gene names: 107022930

Gene position: 1516017-1514650 (Counterclockwise)

Preceding gene: 107022932

Following gene: 107022927

Centisome position: 46.02

GC content: 66.23

Gene sequence:

>1368_bases
ATGCCTTACGTCCTGATCGTCGAAGACGACGCCGATACGCGAACGATGCTCGCCACGCTCGCACGCACGCAGCAATTGAC
GTGCGATACGGCCGCGACGCTTGAAGAAGCGCGCACGCTCGTCTCGACGCATACCCCCGATCTCGTGCTGTGCGACCTCG
TGCTGCCCGACGGCAACGGGATGGATCTGTTCGACGCATTGCCCAAGCGCGCACATTGCGAAATAGTGTTGACCACCGGC
CACGCGAGCCTCGAAACCGCGATCGACGCATTGCGCCGCGGCGCGACCGATTACCTGGTGAAGCCGCTCAACATGCAGCG
GCTGAACAGCATCTTCGCGCGCGTGCCGCGCACGACCGCGCTGCACGAGGAAATCGCCGAGTTGCGCTCGGAATTGCAGC
GCCTCGGCCGTTTCGGCCGCATGCTCGGCAGTTCGCCCGCGATGCAGGCCGTGTACGACGCGATCGGCCGCGTCGCGCGC
ACCGAAGCGTCGGTGCTGCTCACCGGTGAGTCTGGCACCGGCAAGGAGCTCGCCGCGCAAACCGTGCACGACTTGAGCCT
GCGCCGCCGCGGCCCGTTCCTCGCGGTGAACTGCGGCGCGATCGCCGCGAATCTCGTCGAGAGCGAGATGTTCGGTCACG
ACCGAGGCAGCTTCACCGGCGCGGAACGCCAGCACAAGGGCTTCTTCGAACGCGCGGACGGCGGCACGCTGTTTCTCGAC
GAAATCACCGAGATGCCGCTCGAATCGCAGGTCAAGCTGCTGCGCGTGCTGGAGACCGGGCGCGTCACGCGGCTCGGCTC
GACGCGCGAGATCGACGTCGACGTGCGCATCGTCGCCGCGACCAATCGCGATCCGGAAGCCGCGATGGCGGACGGCAAGC
TGCGGCCCGACCTGTTCCACCGGATCAACGTGTTCCCGATTCCGCTGCCGTCGCTGCGCGAACGCGGCGACGACATCCCG
ATGCTCGCCGATGCCTTCCTGCAGCGCTACAACGAGGAAAGTGGCCGCAACCTGCGGTTCGCGCCCGCCGTCCGCGAAGC
GCTGAAGACCTACGAATGGCCCGGCAACGTGCGCGAGCTGCGCAACTTCGTGCAGCGCGCGAGCATCTTCACCGACGCCG
ATGTGATCGAAACGCTGCCGCCACCGATCATGGACGAGCTGTCCAGCATGGTCGATTCGCATGAAGATCGCGTGACGGTG
CCGTTCGGCACGCCGCTCGAGGAAGTCGACCGCAAGCTGATCCTCGGCACGATCGCGCAATGCGGCGGCGTGAAGGCGCA
AGCGGCCGAGGTGCTCGACGTCAGCCTGAAGACGATCTACAACCGGCTCGCGCAACTGGAAGACGAAGCGGAGAAGCCGG
ATTCCTGA

Upstream 100 bases:

>100_bases
GCCCGTTCGTGTGCAGCGTTGAAGATGATGACGCGCATGACGCTGCACGTGCCGCGGTGCCGGCCGATGCACGCGCCGGG
CCGCATTACAAGGAGCCTTG

Downstream 100 bases:

>100_bases
TGCCGCTACGACCGCGTTCACGTTTCCGTTCCGGCCTCGCGGCGCGTGTCGTGCTCGAGGCGGCGGCGCATGCGTTCGAC
GTGCGGCGGGATCGTGCGTC

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MPYVLIVEDDADTRTMLATLARTQQLTCDTAATLEEARTLVSTHTPDLVLCDLVLPDGNGMDLFDALPKRAHCEIVLTTG
HASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTTALHEEIAELRSELQRLGRFGRMLGSSPAMQAVYDAIGRVAR
TEASVLLTGESGTGKELAAQTVHDLSLRRRGPFLAVNCGAIAANLVESEMFGHDRGSFTGAERQHKGFFERADGGTLFLD
EITEMPLESQVKLLRVLETGRVTRLGSTREIDVDVRIVAATNRDPEAAMADGKLRPDLFHRINVFPIPLPSLRERGDDIP
MLADAFLQRYNEESGRNLRFAPAVREALKTYEWPGNVRELRNFVQRASIFTDADVIETLPPPIMDELSSMVDSHEDRVTV
PFGTPLEEVDRKLILGTIAQCGGVKAQAAEVLDVSLKTIYNRLAQLEDEAEKPDS

Sequences:

>Translated_455_residues
MPYVLIVEDDADTRTMLATLARTQQLTCDTAATLEEARTLVSTHTPDLVLCDLVLPDGNGMDLFDALPKRAHCEIVLTTG
HASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTTALHEEIAELRSELQRLGRFGRMLGSSPAMQAVYDAIGRVAR
TEASVLLTGESGTGKELAAQTVHDLSLRRRGPFLAVNCGAIAANLVESEMFGHDRGSFTGAERQHKGFFERADGGTLFLD
EITEMPLESQVKLLRVLETGRVTRLGSTREIDVDVRIVAATNRDPEAAMADGKLRPDLFHRINVFPIPLPSLRERGDDIP
MLADAFLQRYNEESGRNLRFAPAVREALKTYEWPGNVRELRNFVQRASIFTDADVIETLPPPIMDELSSMVDSHEDRVTV
PFGTPLEEVDRKLILGTIAQCGGVKAQAAEVLDVSLKTIYNRLAQLEDEAEKPDS
>Mature_454_residues
PYVLIVEDDADTRTMLATLARTQQLTCDTAATLEEARTLVSTHTPDLVLCDLVLPDGNGMDLFDALPKRAHCEIVLTTGH
ASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTTALHEEIAELRSELQRLGRFGRMLGSSPAMQAVYDAIGRVART
EASVLLTGESGTGKELAAQTVHDLSLRRRGPFLAVNCGAIAANLVESEMFGHDRGSFTGAERQHKGFFERADGGTLFLDE
ITEMPLESQVKLLRVLETGRVTRLGSTREIDVDVRIVAATNRDPEAAMADGKLRPDLFHRINVFPIPLPSLRERGDDIPM
LADAFLQRYNEESGRNLRFAPAVREALKTYEWPGNVRELRNFVQRASIFTDADVIETLPPPIMDELSSMVDSHEDRVTVP
FGTPLEEVDRKLILGTIAQCGGVKAQAAEVLDVSLKTIYNRLAQLEDEAEKPDS

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=38.4105960264901, Blast_Score=321, Evalue=6e-89,
Organism=Escherichia coli, GI1790437, Length=450, Percent_Identity=38, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1790299, Length=465, Percent_Identity=37.2043010752688, Blast_Score=287, Evalue=9e-79,
Organism=Escherichia coli, GI1788905, Length=376, Percent_Identity=39.0957446808511, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1789087, Length=406, Percent_Identity=40.1477832512315, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI87082117, Length=339, Percent_Identity=41.0029498525074, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=39.4984326018809, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1786524, Length=323, Percent_Identity=40.8668730650155, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87082152, Length=235, Percent_Identity=45.9574468085106, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=45.4148471615721, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787583, Length=253, Percent_Identity=39.5256916996047, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789828, Length=368, Percent_Identity=30.9782608695652, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI87081858, Length=291, Percent_Identity=29.553264604811, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1786838, Length=129, Percent_Identity=34.8837209302326, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50257; Mature: 50126

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYVLIVEDDADTRTMLATLARTQQLTCDTAATLEEARTLVSTHTPDLVLCDLVLPDGNG
CCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
MDLFDALPKRAHCEIVLTTGHASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTTA
CCHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCHHH
LHEEIAELRSELQRLGRFGRMLGSSPAMQAVYDAIGRVARTEASVLLTGESGTGKELAAQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
TVHDLSLRRRGPFLAVNCGAIAANLVESEMFGHDRGSFTGAERQHKGFFERADGGTLFLD
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEECCCCEEEHH
EITEMPLESQVKLLRVLETGRVTRLGSTREIDVDVRIVAATNRDPEAAMADGKLRPDLFH
HHHCCCHHHHHHHHHHHHCCCEEECCCCEEEEEEEEEEEECCCCCCHHHCCCCCCHHHHH
RINVFPIPLPSLRERGDDIPMLADAFLQRYNEESGRNLRFAPAVREALKTYEWPGNVREL
HCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECHHHHHHHHHCCCCCCHHHH
RNFVQRASIFTDADVIETLPPPIMDELSSMVDSHEDRVTVPFGTPLEEVDRKLILGTIAQ
HHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHH
CGGVKAQAAEVLDVSLKTIYNRLAQLEDEAEKPDS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PYVLIVEDDADTRTMLATLARTQQLTCDTAATLEEARTLVSTHTPDLVLCDLVLPDGNG
CEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
MDLFDALPKRAHCEIVLTTGHASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTTA
CCHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCHHH
LHEEIAELRSELQRLGRFGRMLGSSPAMQAVYDAIGRVARTEASVLLTGESGTGKELAAQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
TVHDLSLRRRGPFLAVNCGAIAANLVESEMFGHDRGSFTGAERQHKGFFERADGGTLFLD
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEECCCCEEEHH
EITEMPLESQVKLLRVLETGRVTRLGSTREIDVDVRIVAATNRDPEAAMADGKLRPDLFH
HHHCCCHHHHHHHHHHHHCCCEEECCCCEEEEEEEEEEEECCCCCCHHHCCCCCCHHHHH
RINVFPIPLPSLRERGDDIPMLADAFLQRYNEESGRNLRFAPAVREALKTYEWPGNVREL
HCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECHHHHHHHHHCCCCCCHHHH
RNFVQRASIFTDADVIETLPPPIMDELSSMVDSHEDRVTVPFGTPLEEVDRKLILGTIAQ
HHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHH
CGGVKAQAAEVLDVSLKTIYNRLAQLEDEAEKPDS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]