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The map label for this gene is evgS [H]

Identifier: 107022927

GI number: 107022927

Start: 1510609

End: 1512915

Strand: Reverse

Name: evgS [H]

Synonym: Bcen_1375

Alternate gene names: 107022927

Gene position: 1512915-1510609 (Counterclockwise)

Preceding gene: 107022930

Following gene: 107022924

Centisome position: 45.92

GC content: 72.3

Gene sequence:

>2307_bases
ATGACCGAAATTGCACGGCCGCAGGCCGGAAATTACGCAACGGCCGTGATGCTGGTCGCGATCGCGACCGTGTTGCAGAC
GCTCGCGATCCGGTTCGGCGGCGTGAATCTGCCGTTCGTGCTGTATTACCCGCTGCTGGCCGGCGCTGCGTGGGCGACGT
CGTTCGTGTTCGGCATCGTGTCGACGGTGGTCAGCGGGCTGCTCGTCTGGACGCTGTTCCTGTCCGATCCGGCCGCCTAT
ACGACGCCGCTGCCCGACCGGCTCGTGCAGCTCGGCACGTTCATCCTGATCGGCGCGCTAGTGTGCGCGGTCGCGTCGCT
GCTGCATCACACGCGGCTGACGAACGATCGCGCGCGCCGACGCGAGGCGGCCGCGCGCCGGCAGTTCGAGGCCGTGCTGC
GCGCCCTGCCGCACGGCGTGATCGCGACCGACCCGAACGGGCGGCTCACCTATCTCAACGCGGCCGCGGCCGAACTCGTC
GGCTGCCGGCCGGACGAGGCGGTGGGGCGGCCGGTGCGCGACGTGCTGCGCATCGTCGATCACGAAGGCCGCCGCGTGCC
GACCACGCCGCTCGACCGTGCGCTCGGCGGCGCCGAGGCGACGTCCGACCGGCACTGGCTGCAGGCCGGCAGCGGCGATC
GGGTGCCGATCGTCGCGGTCGCGTCGCCGATCGGCGATGCGGACGGCAACCTGGACGGCGCGGTGCTGCTGCTGCGCGAT
GCCGGCGCGGACCGCGCGCGTGTCGATGCGTCGCGGCTCCAGCATGCGGTCGTCGAGGCGTCGCCGGACGCGATCGTCGG
GATCGACGCCGACGGCCGCATCGCCAGCTGGAACGCGGCTGCGCAGCGGATCTTCGGCTACGACGAGGCCGACGCGCGCG
GCCGCAGGTTCGACACGCTGATCGCGCGGCGCTGGCTGCGGCTCAATCCGCTCGCCGACGCGTTCGACGCGATGCACGAG
CCGGTCGGGCCGCTCGAACTGTTGTGCGTGCGGCGCGACGGGCGGCGCTTTCGGGCGACGGTATCGGCGTGCCCGGTGCA
GGGCGAGGCGCGGGCGTGCGTCACGCTGTCCCTGACGCTGCACGAAACCGGCGCGCAGCGTCGCCGCGACCTGCGGGCGC
AGCGCTCGCTGCAGGGCGCGCGCGATGCACGCGATCAGGCCGACACGTCGAACCGGCTGAAGGACGAGCTGCTGGCCACG
GTGTCGCATGAATTGCGCACGCCGCTGAACGTGATCTACGGGTGGATCGAGGTGCTGCGCAATACGGGCGATCACGCGTT
GCAGCATCAGGCGATCGACGCGATCGACCGCAGCGCGCGTTCGCTCACGCGGATGGTCGGCGACATCCTCGATGCGTCGT
CGCTCGCGACCGGCAAGCTGCGGCTCGACGCGACGCCGGTCGACGTCGTGCGGTTGTTCTCCGACCAGGTCGGCACGTTC
CAGACCGCCGCCTCGTCGGCCGGCATCCTGCTCGAATTCGACTGCGCCGCGTCCGCGTGCATCGTGTCGGGCGACGCCGA
GCGGTTGCGGCAGATGCTGTCGAACCTCATCTCGAATGCGCTGAAATTCACGCCGGGCGGCGGCAGCGTGACGGTCGGCC
TCGCGCGCGACGGCGGGCACGCGGTGTTGACCGTCGCCGATACGGGGCAGGGCATCGCGACGGAGTTCACGCCGTACGTG
TTCGACATGTTCCGCCGCGCGGACGATTCGCCCGCGTCGCCGCGGCGCGGGCTCGGTCTCGGCCTGTCGATCGTTCGTCA
CATCGCGCAACTGCACGGCGGCAACGTGACCGTCGCGAGCGCGGGCCGCGACCGCGGCACGACGTTCACGGTGACGCTGC
CGGCCGGCTGGCAGCCGGGCGGCGCGATGGCGTGGAGCATCGTGCAGGCGGGCGGGCAGCGCGAGGCGCTCGTGCTCGAT
ACGCAGCGCATCCTGATCGTCGACGACGACGCGACCACGCGGGCCAGTCTCACCGCCGCGCTGACCACGTTCGGCGCGGC
GGTCGCGATCGCGTCGTCGGGCCGCGAGGCGCTCGCGATGGTGGCCGACATGCGGCCGACGGTCGTGCTGTCCGACCTCG
CGATGCCCGACGGCGACGGCTTCTGGCTGCTGGAGGCCTTGCGGCGCGGCACGACGAACGGCGACAGCGGCCCGCTCGAC
GTGCGCGTGCTGGCCGTCACCGCGCACGCGGGCCTCGCCGACGAACGCCGCGCGCTGGAGGCCGGCTTCGACGGCTACCT
GTGCAAGCCGGTCGACGTGCGCGAACTGGCGCACAAGATCGCGCACGTGACGAAGCGCGACGGCTGA

Upstream 100 bases:

>100_bases
TGAGCGGCCGGGCCGCCGGTTCCGATCGGCCAGCATGCGTCGTGCCCGCGGGCGGCGCCCGCGCCGGCCGCTGTCGAGTG
TCCCCGCAGGAGCGTGTCCA

Downstream 100 bases:

>100_bases
CACGCGTCGCGTCTCGGTTGCTTCGGCCGCGTCAGCCGCGTCACGTCGTCGGCGCCGGCCGATTCTGCGTATGGACCTGG
GCGAGCAGATGCGACGCGAT

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 768; Mature: 767

Protein sequence:

>768_residues
MTEIARPQAGNYATAVMLVAIATVLQTLAIRFGGVNLPFVLYYPLLAGAAWATSFVFGIVSTVVSGLLVWTLFLSDPAAY
TTPLPDRLVQLGTFILIGALVCAVASLLHHTRLTNDRARRREAAARRQFEAVLRALPHGVIATDPNGRLTYLNAAAAELV
GCRPDEAVGRPVRDVLRIVDHEGRRVPTTPLDRALGGAEATSDRHWLQAGSGDRVPIVAVASPIGDADGNLDGAVLLLRD
AGADRARVDASRLQHAVVEASPDAIVGIDADGRIASWNAAAQRIFGYDEADARGRRFDTLIARRWLRLNPLADAFDAMHE
PVGPLELLCVRRDGRRFRATVSACPVQGEARACVTLSLTLHETGAQRRRDLRAQRSLQGARDARDQADTSNRLKDELLAT
VSHELRTPLNVIYGWIEVLRNTGDHALQHQAIDAIDRSARSLTRMVGDILDASSLATGKLRLDATPVDVVRLFSDQVGTF
QTAASSAGILLEFDCAASACIVSGDAERLRQMLSNLISNALKFTPGGGSVTVGLARDGGHAVLTVADTGQGIATEFTPYV
FDMFRRADDSPASPRRGLGLGLSIVRHIAQLHGGNVTVASAGRDRGTTFTVTLPAGWQPGGAMAWSIVQAGGQREALVLD
TQRILIVDDDATTRASLTAALTTFGAAVAIASSGREALAMVADMRPTVVLSDLAMPDGDGFWLLEALRRGTTNGDSGPLD
VRVLAVTAHAGLADERRALEAGFDGYLCKPVDVRELAHKIAHVTKRDG

Sequences:

>Translated_768_residues
MTEIARPQAGNYATAVMLVAIATVLQTLAIRFGGVNLPFVLYYPLLAGAAWATSFVFGIVSTVVSGLLVWTLFLSDPAAY
TTPLPDRLVQLGTFILIGALVCAVASLLHHTRLTNDRARRREAAARRQFEAVLRALPHGVIATDPNGRLTYLNAAAAELV
GCRPDEAVGRPVRDVLRIVDHEGRRVPTTPLDRALGGAEATSDRHWLQAGSGDRVPIVAVASPIGDADGNLDGAVLLLRD
AGADRARVDASRLQHAVVEASPDAIVGIDADGRIASWNAAAQRIFGYDEADARGRRFDTLIARRWLRLNPLADAFDAMHE
PVGPLELLCVRRDGRRFRATVSACPVQGEARACVTLSLTLHETGAQRRRDLRAQRSLQGARDARDQADTSNRLKDELLAT
VSHELRTPLNVIYGWIEVLRNTGDHALQHQAIDAIDRSARSLTRMVGDILDASSLATGKLRLDATPVDVVRLFSDQVGTF
QTAASSAGILLEFDCAASACIVSGDAERLRQMLSNLISNALKFTPGGGSVTVGLARDGGHAVLTVADTGQGIATEFTPYV
FDMFRRADDSPASPRRGLGLGLSIVRHIAQLHGGNVTVASAGRDRGTTFTVTLPAGWQPGGAMAWSIVQAGGQREALVLD
TQRILIVDDDATTRASLTAALTTFGAAVAIASSGREALAMVADMRPTVVLSDLAMPDGDGFWLLEALRRGTTNGDSGPLD
VRVLAVTAHAGLADERRALEAGFDGYLCKPVDVRELAHKIAHVTKRDG
>Mature_767_residues
TEIARPQAGNYATAVMLVAIATVLQTLAIRFGGVNLPFVLYYPLLAGAAWATSFVFGIVSTVVSGLLVWTLFLSDPAAYT
TPLPDRLVQLGTFILIGALVCAVASLLHHTRLTNDRARRREAAARRQFEAVLRALPHGVIATDPNGRLTYLNAAAAELVG
CRPDEAVGRPVRDVLRIVDHEGRRVPTTPLDRALGGAEATSDRHWLQAGSGDRVPIVAVASPIGDADGNLDGAVLLLRDA
GADRARVDASRLQHAVVEASPDAIVGIDADGRIASWNAAAQRIFGYDEADARGRRFDTLIARRWLRLNPLADAFDAMHEP
VGPLELLCVRRDGRRFRATVSACPVQGEARACVTLSLTLHETGAQRRRDLRAQRSLQGARDARDQADTSNRLKDELLATV
SHELRTPLNVIYGWIEVLRNTGDHALQHQAIDAIDRSARSLTRMVGDILDASSLATGKLRLDATPVDVVRLFSDQVGTFQ
TAASSAGILLEFDCAASACIVSGDAERLRQMLSNLISNALKFTPGGGSVTVGLARDGGHAVLTVADTGQGIATEFTPYVF
DMFRRADDSPASPRRGLGLGLSIVRHIAQLHGGNVTVASAGRDRGTTFTVTLPAGWQPGGAMAWSIVQAGGQREALVLDT
QRILIVDDDATTRASLTAALTTFGAAVAIASSGREALAMVADMRPTVVLSDLAMPDGDGFWLLEALRRGTTNGDSGPLDV
RVLAVTAHAGLADERRALEAGFDGYLCKPVDVRELAHKIAHVTKRDG

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=514, Percent_Identity=29.1828793774319, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1788713, Length=533, Percent_Identity=27.3921200750469, Blast_Score=159, Evalue=8e-40,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=31.6793893129771, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI87081816, Length=386, Percent_Identity=28.2383419689119, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=29.9559471365639, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1786600, Length=360, Percent_Identity=26.9444444444444, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=30.6772908366534, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=33.9366515837104, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=27.3092369477912, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1788549, Length=372, Percent_Identity=24.7311827956989, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1790436, Length=257, Percent_Identity=30.7392996108949, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1790551, Length=209, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=28.7610619469027, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=203, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=27.7056277056277, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=37.3913043478261, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787487, Length=110, Percent_Identity=34.5454545454545, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788394, Length=127, Percent_Identity=31.496062992126, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81871; Mature: 81740

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIARPQAGNYATAVMLVAIATVLQTLAIRFGGVNLPFVLYYPLLAGAAWATSFVFGIV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
STVVSGLLVWTLFLSDPAAYTTPLPDRLVQLGTFILIGALVCAVASLLHHTRLTNDRARR
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
REAAARRQFEAVLRALPHGVIATDPNGRLTYLNAAAAELVGCRPDEAVGRPVRDVLRIVD
HHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHCCCCCHHHCCCHHHHHHHHC
HEGRRVPTTPLDRALGGAEATSDRHWLQAGSGDRVPIVAVASPIGDADGNLDGAVLLLRD
CCCCCCCCCHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEE
AGADRARVDASRLQHAVVEASPDAIVGIDADGRIASWNAAAQRIFGYDEADARGRRFDTL
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECHHHHHHHHCCCCCCCCCCCHHHHH
IARRWLRLNPLADAFDAMHEPVGPLELLCVRRDGRRFRATVSACPVQGEARACVTLSLTL
HHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEEEHHHCCCCCCCCEEEEEEEEE
HETGAQRRRDLRAQRSLQGARDARDQADTSNRLKDELLATVSHELRTPLNVIYGWIEVLR
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
NTGDHALQHQAIDAIDRSARSLTRMVGDILDASSLATGKLRLDATPVDVVRLFSDQVGTF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHCCCCH
QTAASSAGILLEFDCAASACIVSGDAERLRQMLSNLISNALKFTPGGGSVTVGLARDGGH
HHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCC
AVLTVADTGQGIATEFTPYVFDMFRRADDSPASPRRGLGLGLSIVRHIAQLHGGNVTVAS
EEEEEECCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
AGRDRGTTFTVTLPAGWQPGGAMAWSIVQAGGQREALVLDTQRILIVDDDATTRASLTAA
CCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCEEEEECCCCCCHHHHHHH
LTTFGAAVAIASSGREALAMVADMRPTVVLSDLAMPDGDGFWLLEALRRGTTNGDSGPLD
HHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCE
VRVLAVTAHAGLADERRALEAGFDGYLCKPVDVRELAHKIAHVTKRDG
EEEEEEEECCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TEIARPQAGNYATAVMLVAIATVLQTLAIRFGGVNLPFVLYYPLLAGAAWATSFVFGIV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
STVVSGLLVWTLFLSDPAAYTTPLPDRLVQLGTFILIGALVCAVASLLHHTRLTNDRARR
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
REAAARRQFEAVLRALPHGVIATDPNGRLTYLNAAAAELVGCRPDEAVGRPVRDVLRIVD
HHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHCCCCCHHHCCCHHHHHHHHC
HEGRRVPTTPLDRALGGAEATSDRHWLQAGSGDRVPIVAVASPIGDADGNLDGAVLLLRD
CCCCCCCCCHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEE
AGADRARVDASRLQHAVVEASPDAIVGIDADGRIASWNAAAQRIFGYDEADARGRRFDTL
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECHHHHHHHHCCCCCCCCCCCHHHHH
IARRWLRLNPLADAFDAMHEPVGPLELLCVRRDGRRFRATVSACPVQGEARACVTLSLTL
HHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEEEHHHCCCCCCCCEEEEEEEEE
HETGAQRRRDLRAQRSLQGARDARDQADTSNRLKDELLATVSHELRTPLNVIYGWIEVLR
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
NTGDHALQHQAIDAIDRSARSLTRMVGDILDASSLATGKLRLDATPVDVVRLFSDQVGTF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHCCCCH
QTAASSAGILLEFDCAASACIVSGDAERLRQMLSNLISNALKFTPGGGSVTVGLARDGGH
HHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCC
AVLTVADTGQGIATEFTPYVFDMFRRADDSPASPRRGLGLGLSIVRHIAQLHGGNVTVAS
EEEEEECCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
AGRDRGTTFTVTLPAGWQPGGAMAWSIVQAGGQREALVLDTQRILIVDDDATTRASLTAA
CCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCEEEEECCCCCCHHHHHHH
LTTFGAAVAIASSGREALAMVADMRPTVVLSDLAMPDGDGFWLLEALRRGTTNGDSGPLD
HHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCE
VRVLAVTAHAGLADERRALEAGFDGYLCKPVDVRELAHKIAHVTKRDG
EEEEEEEECCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]