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The map label for this gene is dgk [H]

Identifier: 107021832

GI number: 107021832

Start: 298623

End: 299309

Strand: Reverse

Name: dgk [H]

Synonym: Bcen_0272

Alternate gene names: 107021832

Gene position: 299309-298623 (Counterclockwise)

Preceding gene: 107021833

Following gene: 107021831

Centisome position: 9.08

GC content: 66.96

Gene sequence:

>687_bases
ATGAACTCGACTCCGCTGACCGTCACCGCGCCCGACCTGCGCGCCCCGCACCGCTATCTCGTGATCGAAGGGCCGATCGG
CGTCGGCAAGACGTCGCTCGCGCGCCTGCTCGGCGAGCGCTGGTCGATGCAGACGCTGCTCGAGCGTCCGCAGGACAATC
CGTTCCTCGAACGCTTCTACCGCGACACCGCGCGCTACGCGCTGCCGGTCCAGCTGTCGTTCGCGCTGCAGCGCGCGCAG
CAGGCGCGCGAGCTGATCGGCGCGCTCGAAACCGGCCGCCCCGTCATCGCCGATTTCATGCCGCAGAAGAACGACATCTT
CGCGCGGCTGAACCTGCCGGAAGACGAGTGGCAGCTGTATCGCTCGATCGCCACGCACGTCGACGTGCCGCAGGCGCCGT
CGCCCGATCTCGTCGTCTATCTGCAGGCCAGCCCCGAAGTGCTGTTCTCGCGCATCCAGAAGCGCGGGCTGCCGATGGAA
CTGCAGATCAGCGACGCGTACCTGCGCTCGCTCGTCGACGCGTACAACGAATTCTTCTACCACTACGACCGCACGCCGGT
GCTGACGGTCGCAGCCGAACACCTGAACCCGCTGGATTCCCCCGACGATCTCGCCCTGCTGGTCGAGCGCATCGAGACGA
TGCGCGGCCGCAAGGAATTCTTCGTCAAGGGCGAGACGACGCGCTGA

Upstream 100 bases:

>100_bases
CCGCCGTCGCGGATCAGCGCGTCGAAAAGGTGCAAACCTGCCAGTGCCTGATGCAGAAGGCGCTCGCTGCCGGCGAAGAC
GCCGACAAGACCCGCTGCCG

Downstream 100 bases:

>100_bases
CGCGTCCCGCCTGTCGCTCTACCCCCATCGACCCGGATTTCCCATGACCTATCTCCAGGAATCGAGCCGGCCTGCCGTGA
CGGTACCCAAGCTGCAGGCA

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MNSTPLTVTAPDLRAPHRYLVIEGPIGVGKTSLARLLGERWSMQTLLERPQDNPFLERFYRDTARYALPVQLSFALQRAQ
QARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLYRSIATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPME
LQISDAYLRSLVDAYNEFFYHYDRTPVLTVAAEHLNPLDSPDDLALLVERIETMRGRKEFFVKGETTR

Sequences:

>Translated_228_residues
MNSTPLTVTAPDLRAPHRYLVIEGPIGVGKTSLARLLGERWSMQTLLERPQDNPFLERFYRDTARYALPVQLSFALQRAQ
QARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLYRSIATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPME
LQISDAYLRSLVDAYNEFFYHYDRTPVLTVAAEHLNPLDSPDDLALLVERIETMRGRKEFFVKGETTR
>Mature_228_residues
MNSTPLTVTAPDLRAPHRYLVIEGPIGVGKTSLARLLGERWSMQTLLERPQDNPFLERFYRDTARYALPVQLSFALQRAQ
QARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLYRSIATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPME
LQISDAYLRSLVDAYNEFFYHYDRTPVLTVAAEHLNPLDSPDDLALLVERIETMRGRKEFFVKGETTR

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 26140; Mature: 26140

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTPLTVTAPDLRAPHRYLVIEGPIGVGKTSLARLLGERWSMQTLLERPQDNPFLERFY
CCCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHH
RDTARYALPVQLSFALQRAQQARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLY
HHHHHEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCHHHHHHH
RSIATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPMELQISDAYLRSLVDAYNEFFY
HHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHH
HYDRTPVLTVAAEHLNPLDSPDDLALLVERIETMRGRKEFFVKGETTR
HCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHCCCHHEEEECCCCC
>Mature Secondary Structure
MNSTPLTVTAPDLRAPHRYLVIEGPIGVGKTSLARLLGERWSMQTLLERPQDNPFLERFY
CCCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHH
RDTARYALPVQLSFALQRAQQARELIGALETGRPVIADFMPQKNDIFARLNLPEDEWQLY
HHHHHEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCHHHHHHH
RSIATHVDVPQAPSPDLVVYLQASPEVLFSRIQKRGLPMELQISDAYLRSLVDAYNEFFY
HHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHH
HYDRTPVLTVAAEHLNPLDSPDDLALLVERIETMRGRKEFFVKGETTR
HCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHCCCHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]