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The map label for this gene is xseA [H]

Identifier: 103488581

GI number: 103488581

Start: 3253329

End: 3254756

Strand: Direct

Name: xseA [H]

Synonym: Sala_3105

Alternate gene names: 103488581

Gene position: 3253329-3254756 (Clockwise)

Preceding gene: 103488578

Following gene: 103488582

Centisome position: 97.25

GC content: 72.06

Gene sequence:

>1428_bases
ATGGCAGTTCCTTTTCCCGATGAGGCGCCCGGCGACGGCACCGACGCGCGGCTGTTAGCCGAGGCGGCGCCCGGCGACAA
TGTGCCGCCGCTGTCCGTCAGCCAATTGTCGGCGGCAATCAAGCGCACCGTCGAGGACGGTTTCGCGCGCGTGCGCGTGC
GCGGCGAGCTGTCGGGGGCGAAGCGCGCGGCATCGGGGCATTTTTATGCGGCGCTGAAAGACGACAATGCCCTCATCGAC
ATGGTGATGTGGAAGGGGCAGGCGGCGCGGCTCGCCTTCCGGCCCGAGGACGGAATCGAGGTGATCGCTACGGGTAAGCT
CACCACCTATCCGGGGCGCTCCAAATATCAGCTCGTCGTCGAAAGCCTGGAGGTCGCGGGCGAAGGCGCGCTGATGCTGC
TCTTCGAGAAATTGAAGGCGCGGCTGGGCGGCGAGGGGCTGTTCGATCGCGACAGAAAGCAGCCGCTTCCCTATCTGCCG
CGCACGATCGGCGTCGTGACCTCCCCCACCGGCGCGGTGATCCGCGACATTCTCCACCGCCTCGCCGACCGCTGCCCCAG
CCATGTGATCGTCTGGCCGGTGCTCGTGCAGGGCGAAGGCGCCGCGGCGCAGGTCGCGGCGGCGATTCGCGGTTTCGACG
CGCTCGCGCCCGGCGGGAAGGTAGCCCGCCCCGACCTGGTGATCGTCGCGCGCGGCGGCGGGTCGATCGAGGATCTGTGG
GCGTTCAACGAGGAGGTCGTCGTGCGCGCGATCGCCGATTGCCGCATCCCGACGATCAGCGCGGTGGGGCATGAAACCGA
CGTGACGCTCGCCGACTATGCCGCCGATATGCGCGCGCCGACGCCGACCGCCGCCGCCGAGATGGCGGTGCCGGTGCGCG
CCGAACTGCAAGCGCAGCTGGCGACGTGGGGCGGGCGGATGATCGGCGCCGCGAACCGGCAGCAGGCTTTGCGGGGCGAG
CGGCTGACGGCGCTCGCGCGGCACCTGCCGCGGCGCGACGCGCTCTATGCGCCGCAGCGCCAGCGGCTCGACGATGTCGG
CGAGCGGCTGGGCCGCGGACAAAGGCAGCGGCTGGCGATGCTGGGCGAGCGGCTTGGCGCGCGCGGCGCGGCGCTGCGCC
CGGCCCTGCTTGCGCGCGCGTGGGACCGCGACCGCGCGAAGCTCGACGGGCTGGGGCGCCTGCTCGCCTCGCTCGACCCG
CGCGCACTCTTGTCGCGCGGCTATGCGATGGTGCGCGATGCTGGCGGAGCGATCGTGACCAGCGCGGCGAAGGCGCGCGA
CGCGGGGCATCTGCGGCTCCAGTTCGCCGACGGCGAGCTGCCCGTGACGGTCGGGGAGGGGGGTGATCCGGCGCCATCGT
CTGGACCGCGCCCGGCGCGCAAGGCATCGCCATCTGCGCCGAAAGCGGGGCAGGGCGAGCTGTTCTGA

Upstream 100 bases:

>100_bases
GTTGCCCGGCGCGGCATAGAGCTTGGCGCAGCTTGGCGATTGTGCCAGTTGCCAGCTCAACGCATGTTCGCGGCCCCCCG
ACCCGATGAGCAGGATATTC

Downstream 100 bases:

>100_bases
GCGCGCAGGGGTGGCTCGCGCGGGCGATCCTGCTATAGTCGCCGCCAACCCTCCCCCGCTCACCGGATATATGCGCCATG
TTGATCGCCAGCCGTAACCG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MAVPFPDEAPGDGTDARLLAEAAPGDNVPPLSVSQLSAAIKRTVEDGFARVRVRGELSGAKRAASGHFYAALKDDNALID
MVMWKGQAARLAFRPEDGIEVIATGKLTTYPGRSKYQLVVESLEVAGEGALMLLFEKLKARLGGEGLFDRDRKQPLPYLP
RTIGVVTSPTGAVIRDILHRLADRCPSHVIVWPVLVQGEGAAAQVAAAIRGFDALAPGGKVARPDLVIVARGGGSIEDLW
AFNEEVVVRAIADCRIPTISAVGHETDVTLADYAADMRAPTPTAAAEMAVPVRAELQAQLATWGGRMIGAANRQQALRGE
RLTALARHLPRRDALYAPQRQRLDDVGERLGRGQRQRLAMLGERLGARGAALRPALLARAWDRDRAKLDGLGRLLASLDP
RALLSRGYAMVRDAGGAIVTSAAKARDAGHLRLQFADGELPVTVGEGGDPAPSSGPRPARKASPSAPKAGQGELF

Sequences:

>Translated_475_residues
MAVPFPDEAPGDGTDARLLAEAAPGDNVPPLSVSQLSAAIKRTVEDGFARVRVRGELSGAKRAASGHFYAALKDDNALID
MVMWKGQAARLAFRPEDGIEVIATGKLTTYPGRSKYQLVVESLEVAGEGALMLLFEKLKARLGGEGLFDRDRKQPLPYLP
RTIGVVTSPTGAVIRDILHRLADRCPSHVIVWPVLVQGEGAAAQVAAAIRGFDALAPGGKVARPDLVIVARGGGSIEDLW
AFNEEVVVRAIADCRIPTISAVGHETDVTLADYAADMRAPTPTAAAEMAVPVRAELQAQLATWGGRMIGAANRQQALRGE
RLTALARHLPRRDALYAPQRQRLDDVGERLGRGQRQRLAMLGERLGARGAALRPALLARAWDRDRAKLDGLGRLLASLDP
RALLSRGYAMVRDAGGAIVTSAAKARDAGHLRLQFADGELPVTVGEGGDPAPSSGPRPARKASPSAPKAGQGELF
>Mature_474_residues
AVPFPDEAPGDGTDARLLAEAAPGDNVPPLSVSQLSAAIKRTVEDGFARVRVRGELSGAKRAASGHFYAALKDDNALIDM
VMWKGQAARLAFRPEDGIEVIATGKLTTYPGRSKYQLVVESLEVAGEGALMLLFEKLKARLGGEGLFDRDRKQPLPYLPR
TIGVVTSPTGAVIRDILHRLADRCPSHVIVWPVLVQGEGAAAQVAAAIRGFDALAPGGKVARPDLVIVARGGGSIEDLWA
FNEEVVVRAIADCRIPTISAVGHETDVTLADYAADMRAPTPTAAAEMAVPVRAELQAQLATWGGRMIGAANRQQALRGER
LTALARHLPRRDALYAPQRQRLDDVGERLGRGQRQRLAMLGERLGARGAALRPALLARAWDRDRAKLDGLGRLLASLDPR
ALLSRGYAMVRDAGGAIVTSAAKARDAGHLRLQFADGELPVTVGEGGDPAPSSGPRPARKASPSAPKAGQGELF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=310, Percent_Identity=42.9032258064516, Blast_Score=248, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50380; Mature: 50249

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPFPDEAPGDGTDARLLAEAAPGDNVPPLSVSQLSAAIKRTVEDGFARVRVRGELSGA
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCH
KRAASGHFYAALKDDNALIDMVMWKGQAARLAFRPEDGIEVIATGKLTTYPGRSKYQLVV
HHCCCCCEEEEECCCCCEEEEEEECCCCEEEEECCCCCCEEEEECCEEECCCCCHHHHHH
ESLEVAGEGALMLLFEKLKARLGGEGLFDRDRKQPLPYLPRTIGVVTSPTGAVIRDILHR
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCEEECCHHHHHHHHHHH
LADRCPSHVIVWPVLVQGEGAAAQVAAAIRGFDALAPGGKVARPDLVIVARGGGSIEDLW
HHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCHHCCCCCCCCCCCEEEEECCCCCHHHHH
AFNEEVVVRAIADCRIPTISAVGHETDVTLADYAADMRAPTPTAAAEMAVPVRAELQAQL
HCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHH
ATWGGRMIGAANRQQALRGERLTALARHLPRRDALYAPQRQRLDDVGERLGRGQRQRLAM
HHCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
LGERLGARGAALRPALLARAWDRDRAKLDGLGRLLASLDPRALLSRGYAMVRDAGGAIVT
HHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCEEEE
SAAKARDAGHLRLQFADGELPVTVGEGGDPAPSSGPRPARKASPSAPKAGQGELF
CHHHCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVPFPDEAPGDGTDARLLAEAAPGDNVPPLSVSQLSAAIKRTVEDGFARVRVRGELSGA
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCH
KRAASGHFYAALKDDNALIDMVMWKGQAARLAFRPEDGIEVIATGKLTTYPGRSKYQLVV
HHCCCCCEEEEECCCCCEEEEEEECCCCEEEEECCCCCCEEEEECCEEECCCCCHHHHHH
ESLEVAGEGALMLLFEKLKARLGGEGLFDRDRKQPLPYLPRTIGVVTSPTGAVIRDILHR
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCEEECCHHHHHHHHHHH
LADRCPSHVIVWPVLVQGEGAAAQVAAAIRGFDALAPGGKVARPDLVIVARGGGSIEDLW
HHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCHHCCCCCCCCCCCEEEEECCCCCHHHHH
AFNEEVVVRAIADCRIPTISAVGHETDVTLADYAADMRAPTPTAAAEMAVPVRAELQAQL
HCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHH
ATWGGRMIGAANRQQALRGERLTALARHLPRRDALYAPQRQRLDDVGERLGRGQRQRLAM
HHCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
LGERLGARGAALRPALLARAWDRDRAKLDGLGRLLASLDPRALLSRGYAMVRDAGGAIVT
HHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCEEEE
SAAKARDAGHLRLQFADGELPVTVGEGGDPAPSSGPRPARKASPSAPKAGQGELF
CHHHCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA