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The map label for this gene is argB

Identifier: 103488571

GI number: 103488571

Start: 3245259

End: 3246167

Strand: Direct

Name: argB

Synonym: Sala_3095

Alternate gene names: 103488571

Gene position: 3245259-3246167 (Clockwise)

Preceding gene: 103488570

Following gene: 103488572

Centisome position: 97.01

GC content: 65.46

Gene sequence:

>909_bases
ATGATGACGATGGCCGATCCTTCGAAAATGCCCGACCTGCTCGCCAAGGCCGAAACACTCGTCGAGGCGCTGCCCTATCT
GCAGCGTTATGCGGGCCAGACCTTTGTCATCAAATATGGCGGCCATGCGATGGGCGATCCGGAGGCGCAGCGCGATTTTG
CCGAGGATGTCGTGCTGCTCAAAGCCGTCGGCATCAACCCGGTCGTCGTCCATGGCGGCGGGCCGCAGATCGGCGCGATG
CTGAAACAGCTCGGGATCGAATCGACCTTCGTGGGCGGGCTGCGCGTCACCGACGCGGCGACGGCCGAGGTTGCGGAAAT
GGTGCTGGCGGGCAAGATCAACAAGGAAATCGTCGGCTGGATCGCGGGCCTCGGCGGCCGCGCGGTCGGCATTTCGGGCA
AGGACGCCAATCTCGTCCTCGCCGAAAAGGTGAAGCGCAGCGAGGCCGACCCCAGTTCGGGGATCGAGCGCCACGTCGAC
CTCGGTTTCGTCGGCGAGCCCGTCGCGGTCGATCCGACGATCCTTGCCAATCTGACGAACGACAATTTCATCCCGGTGGT
GGCGCCGGTCGCGCTCGGCGCCGACGGCGCGACCTATAATATCAACGCCGACACGATGGCGGGCGCGATCGCCGGGGCGC
TCGGCGCCAAGCGTTTCTTCCTGCTCACCGATGTCGCGGGGGTGCTCGACAAGTCGGGGGCCTTGCTCACCGACCTCGAC
CGTGCGGCGATCGATGCGCTCAAGGCGGACGACACGATAACCGGCGGCATGATCCCCAAGGTCGAAACCTGCGTCGCCGC
GGTCGACGCGGGGGTCGAGGCGGCGGTCATCCTCGACGGGCGGATCCCGCACGCGATGCTGCTCGAAATTTTTACCACAA
GGGGTGCGGGCACGCTCATTCACCGTTAA

Upstream 100 bases:

>100_bases
GACAGATGCTCGCCAAGGTCGTGCTGTCGGTGCTCGTCATTCCCTTCGTCATCACCGGGCTGGTCGCGCTGGGCCGCAGC
CTCGATGCGAAAAACGCCGG

Downstream 100 bases:

>100_bases
GATCGTCGCCATCGACCTTTCGGCCGGAGACTTTCCTTGTATTTCATGCTTCTCGATATTCTGTCGATCCTGCTCAACAT
CCTGTGGTGGATCATCATCG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MMTMADPSKMPDLLAKAETLVEALPYLQRYAGQTFVIKYGGHAMGDPEAQRDFAEDVVLLKAVGINPVVVHGGGPQIGAM
LKQLGIESTFVGGLRVTDAATAEVAEMVLAGKINKEIVGWIAGLGGRAVGISGKDANLVLAEKVKRSEADPSSGIERHVD
LGFVGEPVAVDPTILANLTNDNFIPVVAPVALGADGATYNINADTMAGAIAGALGAKRFFLLTDVAGVLDKSGALLTDLD
RAAIDALKADDTITGGMIPKVETCVAAVDAGVEAAVILDGRIPHAMLLEIFTTRGAGTLIHR

Sequences:

>Translated_302_residues
MMTMADPSKMPDLLAKAETLVEALPYLQRYAGQTFVIKYGGHAMGDPEAQRDFAEDVVLLKAVGINPVVVHGGGPQIGAM
LKQLGIESTFVGGLRVTDAATAEVAEMVLAGKINKEIVGWIAGLGGRAVGISGKDANLVLAEKVKRSEADPSSGIERHVD
LGFVGEPVAVDPTILANLTNDNFIPVVAPVALGADGATYNINADTMAGAIAGALGAKRFFLLTDVAGVLDKSGALLTDLD
RAAIDALKADDTITGGMIPKVETCVAAVDAGVEAAVILDGRIPHAMLLEIFTTRGAGTLIHR
>Mature_302_residues
MMTMADPSKMPDLLAKAETLVEALPYLQRYAGQTFVIKYGGHAMGDPEAQRDFAEDVVLLKAVGINPVVVHGGGPQIGAM
LKQLGIESTFVGGLRVTDAATAEVAEMVLAGKINKEIVGWIAGLGGRAVGISGKDANLVLAEKVKRSEADPSSGIERHVD
LGFVGEPVAVDPTILANLTNDNFIPVVAPVALGADGATYNINADTMAGAIAGALGAKRFFLLTDVAGVLDKSGALLTDLD
RAAIDALKADDTITGGMIPKVETCVAAVDAGVEAAVILDGRIPHAMLLEIFTTRGAGTLIHR

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=287, Percent_Identity=26.4808362369338, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI145693208, Length=237, Percent_Identity=32.0675105485232, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320913, Length=305, Percent_Identity=26.2295081967213, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_SPHAL (Q1GNH3)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_618132.1
- ProteinModelPortal:   Q1GNH3
- SMR:   Q1GNH3
- GeneID:   4082831
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_3095
- NMPDR:   fig|317655.9.peg.2947
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   SALA317655:SALA_3095-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31189; Mature: 31189

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: BINDING 95-95 BINDING 200-200

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTMADPSKMPDLLAKAETLVEALPYLQRYAGQTFVIKYGGHAMGDPEAQRDFAEDVVLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHEE
KAVGINPVVVHGGGPQIGAMLKQLGIESTFVGGLRVTDAATAEVAEMVLAGKINKEIVGW
EECCCCEEEEECCCCHHHHHHHHHCCCCEEECCEEECCHHHHHHHHHHHHCCCCHHHHHH
IAGLGGRAVGISGKDANLVLAEKVKRSEADPSSGIERHVDLGFVGEPVAVDPTILANLTN
HHCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCEECCEEEEECCC
DNFIPVVAPVALGADGATYNINADTMAGAIAGALGAKRFFLLTDVAGVLDKSGALLTDLD
CCCEEEEEHEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RAAIDALKADDTITGGMIPKVETCVAAVDAGVEAAVILDGRIPHAMLLEIFTTRGAGTLI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCCCC
HR
CC
>Mature Secondary Structure
MMTMADPSKMPDLLAKAETLVEALPYLQRYAGQTFVIKYGGHAMGDPEAQRDFAEDVVLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHEE
KAVGINPVVVHGGGPQIGAMLKQLGIESTFVGGLRVTDAATAEVAEMVLAGKINKEIVGW
EECCCCEEEEECCCCHHHHHHHHHCCCCEEECCEEECCHHHHHHHHHHHHCCCCHHHHHH
IAGLGGRAVGISGKDANLVLAEKVKRSEADPSSGIERHVDLGFVGEPVAVDPTILANLTN
HHCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCEECCEEEEECCC
DNFIPVVAPVALGADGATYNINADTMAGAIAGALGAKRFFLLTDVAGVLDKSGALLTDLD
CCCEEEEEHEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RAAIDALKADDTITGGMIPKVETCVAAVDAGVEAAVILDGRIPHAMLLEIFTTRGAGTLI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCCCC
HR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA