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The map label for this gene is gluQ [H]

Identifier: 103488560

GI number: 103488560

Start: 3236276

End: 3237139

Strand: Direct

Name: gluQ [H]

Synonym: Sala_3084

Alternate gene names: 103488560

Gene position: 3236276-3237139 (Clockwise)

Preceding gene: 103488556

Following gene: 103488561

Centisome position: 96.74

GC content: 72.45

Gene sequence:

>864_bases
ATGGCACCGAAGATGCTGACCCGCTTCGCCCCCAGCCCGACCGGCGAGCTGCACCTTGGCCACGCCTATAGCGCGGTTCT
GGCGCACCATGCCGCACGCGCGGCGGGCGGGCGGTTCCGCATCCGCATCGACGACATCGACGGCAGCCGGTCGCGCGAAG
CCTATGTCGATGCCGCGCTTGCCGACCTTGCGTGGCTCGGGATCGGCCGGGACGGCGATCCGGTGCGCCAGTCCGACCGG
CTCGGCGATTATGCCGCGGCGCTCGACGATCTCGACGCGCGCGGCCTTGTCTATCCCTGTTTCTGCACGCGCGCCGACAT
CGCCGCGAGCCTGTCGGCGCCGCACGGGCCGTCCGGCGCCATCTATCCCGGCACCTGCCGCGATCTGCCCGCCGCCGAGC
GCGCGCGGCGCAGGGCGGCCGAACCCCATTGCTGGCGGCTCGACATGGCGCGCGCCGTCGCGCTGGCGGGCGAACTCGAC
TGGGAAGAGGTGGGGCAGGGGATGCGCCGCGCCGACCCCGCGGCGCACGGCGATATTGTGCTCGCACGCAAGGACGCGCC
CGCGAGCTATCATCTGGCGAGCACGCTCGACGACGCCGCGATGGGGGTTACGCATGTCATCCGCGGCGCGGACCTTGTCG
CCGCGACCGACATCCACCGGCTGCTCCAGGCGCTGCTCGGTCTCGCCACGCCTGCCTATCGCCACCATGCGCTCGTCTGC
GGCGTCGACGGCAAAAGGCTCGCGAAGCGCGACGCCGCCGCGTCGCTCGCGTCGCTGCGCGCCGCAGGCGTCGACGGAGC
CGCGCTCGCTGCCGATTTGCGGTGCGGACGGCTTCCCGCTGGATATTCGCTGCGAATGCCCTAA

Upstream 100 bases:

>100_bases
TGACACCATCATTACATGCCGCATCAGATTCTGGCGTCAAGGGCCTTCTGCCCGCAAGATATGGAATGATTCGCTTTGAC
TCGCCACAGTATATGGGTTG

Downstream 100 bases:

>100_bases
ATAGGGCTTATGGAAATCCTGCTCGTCCTTGGCGTCGTCATCGCCGCCGGTCTCGTCCTGTTCGCGCTCGCACGCGGGCT
TTTCCATTTCTCGCAGGGGC

Product: glutamyl-tRNA synthetase, class Ic

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MAPKMLTRFAPSPTGELHLGHAYSAVLAHHAARAAGGRFRIRIDDIDGSRSREAYVDAALADLAWLGIGRDGDPVRQSDR
LGDYAAALDDLDARGLVYPCFCTRADIAASLSAPHGPSGAIYPGTCRDLPAAERARRRAAEPHCWRLDMARAVALAGELD
WEEVGQGMRRADPAAHGDIVLARKDAPASYHLASTLDDAAMGVTHVIRGADLVAATDIHRLLQALLGLATPAYRHHALVC
GVDGKRLAKRDAAASLASLRAAGVDGAALAADLRCGRLPAGYSLRMP

Sequences:

>Translated_287_residues
MAPKMLTRFAPSPTGELHLGHAYSAVLAHHAARAAGGRFRIRIDDIDGSRSREAYVDAALADLAWLGIGRDGDPVRQSDR
LGDYAAALDDLDARGLVYPCFCTRADIAASLSAPHGPSGAIYPGTCRDLPAAERARRRAAEPHCWRLDMARAVALAGELD
WEEVGQGMRRADPAAHGDIVLARKDAPASYHLASTLDDAAMGVTHVIRGADLVAATDIHRLLQALLGLATPAYRHHALVC
GVDGKRLAKRDAAASLASLRAAGVDGAALAADLRCGRLPAGYSLRMP
>Mature_286_residues
APKMLTRFAPSPTGELHLGHAYSAVLAHHAARAAGGRFRIRIDDIDGSRSREAYVDAALADLAWLGIGRDGDPVRQSDRL
GDYAAALDDLDARGLVYPCFCTRADIAASLSAPHGPSGAIYPGTCRDLPAAERARRRAAEPHCWRLDMARAVALAGELDW
EEVGQGMRRADPAAHGDIVLARKDAPASYHLASTLDDAAMGVTHVIRGADLVAATDIHRLLQALLGLATPAYRHHALVCG
VDGKRLAKRDAAASLASLRAAGVDGAALAADLRCGRLPAGYSLRMP

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=270, Percent_Identity=32.5925925925926, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI226510925, Length=256, Percent_Identity=35.15625, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788743, Length=268, Percent_Identity=31.7164179104478, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71993394, Length=284, Percent_Identity=29.2253521126761, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324540, Length=274, Percent_Identity=33.2116788321168, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24665321, Length=277, Percent_Identity=32.4909747292419, Blast_Score=131, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 30313; Mature: 30182

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPKMLTRFAPSPTGELHLGHAYSAVLAHHAARAAGGRFRIRIDDIDGSRSREAYVDAAL
CCCHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
ADLAWLGIGRDGDPVRQSDRLGDYAAALDDLDARGLVYPCFCTRADIAASLSAPHGPSGA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHCHHHHHHHCCCCCCCCCC
IYPGTCRDLPAAERARRRAAEPHCWRLDMARAVALAGELDWEEVGQGMRRADPAAHGDIV
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHCCCCCCCCEE
LARKDAPASYHLASTLDDAAMGVTHVIRGADLVAATDIHRLLQALLGLATPAYRHHALVC
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHCCEEEE
GVDGKRLAKRDAAASLASLRAAGVDGAALAADLRCGRLPAGYSLRMP
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEECCC
>Mature Secondary Structure 
APKMLTRFAPSPTGELHLGHAYSAVLAHHAARAAGGRFRIRIDDIDGSRSREAYVDAAL
CCHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
ADLAWLGIGRDGDPVRQSDRLGDYAAALDDLDARGLVYPCFCTRADIAASLSAPHGPSGA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHCHHHHHHHCCCCCCCCCC
IYPGTCRDLPAAERARRRAAEPHCWRLDMARAVALAGELDWEEVGQGMRRADPAAHGDIV
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHCCCCCCCCEE
LARKDAPASYHLASTLDDAAMGVTHVIRGADLVAATDIHRLLQALLGLATPAYRHHALVC
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHCCEEEE
GVDGKRLAKRDAAASLASLRAAGVDGAALAADLRCGRLPAGYSLRMP
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA