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The map label for this gene is exoC [H]

Identifier: 103488478

GI number: 103488478

Start: 3143714

End: 3145096

Strand: Reverse

Name: exoC [H]

Synonym: Sala_3001

Alternate gene names: 103488478

Gene position: 3145096-3143714 (Counterclockwise)

Preceding gene: 103488479

Following gene: 103488477

Centisome position: 94.02

GC content: 65.94

Gene sequence:

>1383_bases
ATGACCCATGATTTCCATCCGACGATGCTGCGCGAATATGACATTCGCGGCGTCGTTGGCGATACGTTGTCCGAAAAGGA
CGCCTATGCCATCGGGCGCAGCTTTGCGACGCTGATCCGCCGCGCGGGGGGCGGACGAATTGCGGTCGGCTATGACGGAC
GGCTGTCGTCGCCGATGCTCGCCGAAGCGCTGGTCGCAGGGGTCAACGCTGCGGGCGTCGATGCGTTGAATGTCGGGCTG
GGACCGACGCCGATGCTCTATTATGCGGCCTCAACGCAGCAGGTCGATGGCGGCATACAGATAACCGGAAGCCATAATCC
CCCCGACTATAACGGCTTCAAGATGGTATTTCAGGGGCGCCCCTTCTTCGGCGCCGACATCCGGCGGATCGGTGAAATGG
CCGCGGCGGGCGACTGGGAGGCGGGCGAAGGCACGGCGGAGCGCATCGACATCGTCGATGCCTATGTCGACCGGCTGGTC
GAGGGGTTCGTCGGCGGCGCCTTCCGCATCGGCTGGGACGCCGGCAACGGGGCAGCGGGCCCCGTGATCGAGAAACTCAC
CGCGCGCTTGCCCGGCGAGCATCATTTGCTTTTCACAGACATTGACGGGCATTTCCCGAACCACCATCCCGATCCGACCG
AGGAGAAGAACCTCGCCGATCTGCGCAAGCTCGTCGCCGAAAAGAGCCTCGATTTCGGCGTCGCCTTCGATGGAGACGGC
GACCGTATCGGCGCGATCGACGGCCAGGGCCGCGTGATCTGGGGCGACCAGCTGCTGCAAATCTATGCCGCCGCGGTGTT
GACCGACCTGCCCGGCGCGACGGTGATCGCCGATGTGAAGGCGAGCCAGGCGCTGTTCGACCGCGTCGCGCAGCTCGGCG
GCACGCCCCTGATGTGGAAGACCGGTCACAGCCTCATCAAGGCGAAGATGAAGGAAACCGGCAGTCCGCTCGCCGGCGAG
ATGAGCGGGCACATCTTCTTCGCCGACCGCTATTACGGTTATGACGACGCCCCTTATGCGGCGGTGCGACTGATCGAGGC
GGCGACGAAGCTCGGGAAAAGCGTCACCGAATTGCGCGGCGGTATGGCGCCGATGGTCAACACGCCCGAAATGCGCTTCC
AGGTCGACGAGGTGCGCAAATTCGCCATTGTGGACGAGGTTCTGGACCGGCTGGCGACGTCGGGCGCGCGCGTCGATCGC
ACCGACGGGGCGCGGGTGATGACCGACGACGGCTGGTGGCTGCTCCGCGCGTCGAACACGCAGGACGTGCTCGTCGCCCG
CGCCGAGGCCGTGGACGAAGCCGCGCTGGCGCGGCTGCTGGTGGCGATCGACGAACAGCTCGCGCAATCGGGCGTCGCGC
GCGGAACGCAGGCGGCGCATTAG

Upstream 100 bases:

>100_bases
GCGATGGGCGGCCTCAACCTGCCCGCGCGCGAGCGACTGCATCCCGACGGCGACCTGTTTGCTGCCGCCTGACCTGCTTC
TCCCCCCAAGAGGATCGACG

Downstream 100 bases:

>100_bases
GCGCGGCCAGGGCGCATCGCATCCTTGCAATAATCCTGCCAGATTGACCTTGGCGCCGTCGCTGGGGTAACGCGGCAGCG
AAGCCAGACGGGAACCGACC

Product: phosphomannomutase

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTHDFHPTMLREYDIRGVVGDTLSEKDAYAIGRSFATLIRRAGGGRIAVGYDGRLSSPMLAEALVAGVNAAGVDALNVGL
GPTPMLYYAASTQQVDGGIQITGSHNPPDYNGFKMVFQGRPFFGADIRRIGEMAAAGDWEAGEGTAERIDIVDAYVDRLV
EGFVGGAFRIGWDAGNGAAGPVIEKLTARLPGEHHLLFTDIDGHFPNHHPDPTEEKNLADLRKLVAEKSLDFGVAFDGDG
DRIGAIDGQGRVIWGDQLLQIYAAAVLTDLPGATVIADVKASQALFDRVAQLGGTPLMWKTGHSLIKAKMKETGSPLAGE
MSGHIFFADRYYGYDDAPYAAVRLIEAATKLGKSVTELRGGMAPMVNTPEMRFQVDEVRKFAIVDEVLDRLATSGARVDR
TDGARVMTDDGWWLLRASNTQDVLVARAEAVDEAALARLLVAIDEQLAQSGVARGTQAAH

Sequences:

>Translated_460_residues
MTHDFHPTMLREYDIRGVVGDTLSEKDAYAIGRSFATLIRRAGGGRIAVGYDGRLSSPMLAEALVAGVNAAGVDALNVGL
GPTPMLYYAASTQQVDGGIQITGSHNPPDYNGFKMVFQGRPFFGADIRRIGEMAAAGDWEAGEGTAERIDIVDAYVDRLV
EGFVGGAFRIGWDAGNGAAGPVIEKLTARLPGEHHLLFTDIDGHFPNHHPDPTEEKNLADLRKLVAEKSLDFGVAFDGDG
DRIGAIDGQGRVIWGDQLLQIYAAAVLTDLPGATVIADVKASQALFDRVAQLGGTPLMWKTGHSLIKAKMKETGSPLAGE
MSGHIFFADRYYGYDDAPYAAVRLIEAATKLGKSVTELRGGMAPMVNTPEMRFQVDEVRKFAIVDEVLDRLATSGARVDR
TDGARVMTDDGWWLLRASNTQDVLVARAEAVDEAALARLLVAIDEQLAQSGVARGTQAAH
>Mature_459_residues
THDFHPTMLREYDIRGVVGDTLSEKDAYAIGRSFATLIRRAGGGRIAVGYDGRLSSPMLAEALVAGVNAAGVDALNVGLG
PTPMLYYAASTQQVDGGIQITGSHNPPDYNGFKMVFQGRPFFGADIRRIGEMAAAGDWEAGEGTAERIDIVDAYVDRLVE
GFVGGAFRIGWDAGNGAAGPVIEKLTARLPGEHHLLFTDIDGHFPNHHPDPTEEKNLADLRKLVAEKSLDFGVAFDGDGD
RIGAIDGQGRVIWGDQLLQIYAAAVLTDLPGATVIADVKASQALFDRVAQLGGTPLMWKTGHSLIKAKMKETGSPLAGEM
SGHIFFADRYYGYDDAPYAAVRLIEAATKLGKSVTELRGGMAPMVNTPEMRFQVDEVRKFAIVDEVLDRLATSGARVDRT
DGARVMTDDGWWLLRASNTQDVLVARAEAVDEAALARLLVAIDEQLAQSGVARGTQAAH

Specific function: Involved In The Biosynthesis Of The Capsular Polysaccharide Colanic Acid. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=460, Percent_Identity=35.2173913043478, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=29.372197309417, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 49294; Mature: 49163

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDFHPTMLREYDIRGVVGDTLSEKDAYAIGRSFATLIRRAGGGRIAVGYDGRLSSPML
CCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
AEALVAGVNAAGVDALNVGLGPTPMLYYAASTQQVDGGIQITGSHNPPDYNGFKMVFQGR
HHHHHHCCCCCCCCEEECCCCCCCEEEEECCCEECCCCEEEECCCCCCCCCCEEEEEECC
PFFGADIRRIGEMAAAGDWEAGEGTAERIDIVDAYVDRLVEGFVGGAFRIGWDAGNGAAG
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
PVIEKLTARLPGEHHLLFTDIDGHFPNHHPDPTEEKNLADLRKLVAEKSLDFGVAFDGDG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCC
DRIGAIDGQGRVIWGDQLLQIYAAAVLTDLPGATVIADVKASQALFDRVAQLGGTPLMWK
CEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEC
TGHSLIKAKMKETGSPLAGEMSGHIFFADRYYGYDDAPYAAVRLIEAATKLGKSVTELRG
CCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GMAPMVNTPEMRFQVDEVRKFAIVDEVLDRLATSGARVDRTDGARVMTDDGWWLLRASNT
CCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCEEEEEECCC
QDVLVARAEAVDEAALARLLVAIDEQLAQSGVARGTQAAH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
THDFHPTMLREYDIRGVVGDTLSEKDAYAIGRSFATLIRRAGGGRIAVGYDGRLSSPML
CCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
AEALVAGVNAAGVDALNVGLGPTPMLYYAASTQQVDGGIQITGSHNPPDYNGFKMVFQGR
HHHHHHCCCCCCCCEEECCCCCCCEEEEECCCEECCCCEEEECCCCCCCCCCEEEEEECC
PFFGADIRRIGEMAAAGDWEAGEGTAERIDIVDAYVDRLVEGFVGGAFRIGWDAGNGAAG
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
PVIEKLTARLPGEHHLLFTDIDGHFPNHHPDPTEEKNLADLRKLVAEKSLDFGVAFDGDG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCC
DRIGAIDGQGRVIWGDQLLQIYAAAVLTDLPGATVIADVKASQALFDRVAQLGGTPLMWK
CEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEC
TGHSLIKAKMKETGSPLAGEMSGHIFFADRYYGYDDAPYAAVRLIEAATKLGKSVTELRG
CCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GMAPMVNTPEMRFQVDEVRKFAIVDEVLDRLATSGARVDRTDGARVMTDDGWWLLRASNT
CCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCEEEEEECCC
QDVLVARAEAVDEAALARLLVAIDEQLAQSGVARGTQAAH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA