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The map label for this gene is 103488354

Identifier: 103488354

GI number: 103488354

Start: 3028408

End: 3029097

Strand: Direct

Name: 103488354

Synonym: Sala_2877

Alternate gene names: NA

Gene position: 3028408-3029097 (Clockwise)

Preceding gene: 103488353

Following gene: 103488355

Centisome position: 90.53

GC content: 73.04

Gene sequence:

>690_bases
ATGAGCGACGGCGCGCCGCTGATCGTCACGCGCCCCGAACCGGGCAATGCGGCGACGGTCGCGCGTGCGCGTGCGCTGGG
TTTTGATGTTCATGCGATGCCGCTGTTCGCCGCGCGGCCGCTCGACTGGACCCCGCCCGACGCCGCCGATTTCGACGCGC
TGCTGCTGACCAGCGCCTTTGCCGCGCGGCTCGCCGGGCCGGGGCTGGGCGCGCTCGCATCGCTTCCCGCCTATGCCGTC
GGCCCGGCCACGGCGGAGGCCGCGCGAGCGGCGGGGCTGACCGTCGCGATGGCCGGGGCGGCTGGCGCCGAGCGGCTTCT
TGACGACATGACATCATCTGAAATCGCGCGAATCCTGTGGCTTTGCGGGCGCGACCGAACGGCGCTTCGGGTTGGCGACG
CGATGCTGGCGCCGCTGCCCTGTTATGCGGTCGATCCGGTCGACCCGCCCCCGGCGTGGAGCGCGCTGATCGCGGCGCCG
GCGATATTGCTCGCGCATTCGGCGCGCGCGGCGGAGCGGGTTGCAGCACTGGCGGGGACGGCGCGCGGGCATCTGTCGCT
GGTGGCGATCAGCGCGGCGGTCGCGCAGGCTGCGGGTGCGGGGTGGCGCGTCTGTGCCGTGGCGGCGGAGGCGAATGATG
CCGCAATGTTGGCACAGGCGCGCGCTTTGTGGCACAAGGGTGCGAAATAG

Upstream 100 bases:

>100_bases
TCGCGGGGCATGTCATCGTCACCGACGCCGGGGTCGTCGCGGCGCTGGGGCATCGGCTGCTGGCCGAAGCGCCGCCGAGC
ATCCGGCGGTTGTTCGCGAC

Downstream 100 bases:

>100_bases
GGTCGTTCGAAAGAGACATATGGCAATCGACAATCTCGATACTTCCTCGTCCGTGGGCGAGGCGGTCCCCGCACGGGGGC
TATCGTTTCGAGCCCTCGCC

Product: uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSDGAPLIVTRPEPGNAATVARARALGFDVHAMPLFAARPLDWTPPDAADFDALLLTSAFAARLAGPGLGALASLPAYAV
GPATAEAARAAGLTVAMAGAAGAERLLDDMTSSEIARILWLCGRDRTALRVGDAMLAPLPCYAVDPVDPPPAWSALIAAP
AILLAHSARAAERVAALAGTARGHLSLVAISAAVAQAAGAGWRVCAVAAEANDAAMLAQARALWHKGAK

Sequences:

>Translated_229_residues
MSDGAPLIVTRPEPGNAATVARARALGFDVHAMPLFAARPLDWTPPDAADFDALLLTSAFAARLAGPGLGALASLPAYAV
GPATAEAARAAGLTVAMAGAAGAERLLDDMTSSEIARILWLCGRDRTALRVGDAMLAPLPCYAVDPVDPPPAWSALIAAP
AILLAHSARAAERVAALAGTARGHLSLVAISAAVAQAAGAGWRVCAVAAEANDAAMLAQARALWHKGAK
>Mature_228_residues
SDGAPLIVTRPEPGNAATVARARALGFDVHAMPLFAARPLDWTPPDAADFDALLLTSAFAARLAGPGLGALASLPAYAVG
PATAEAARAAGLTVAMAGAAGAERLLDDMTSSEIARILWLCGRDRTALRVGDAMLAPLPCYAVDPVDPPPAWSALIAAPA
ILLAHSARAAERVAALAGTARGHLSLVAISAAVAQAAGAGWRVCAVAAEANDAAMLAQARALWHKGAK

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 23049; Mature: 22918

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGAPLIVTRPEPGNAATVARARALGFDVHAMPLFAARPLDWTPPDAADFDALLLTSAF
CCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHH
AARLAGPGLGALASLPAYAVGPATAEAARAAGLTVAMAGAAGAERLLDDMTSSEIARILW
HHHHCCCCCHHHHHCCCHHCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
LCGRDRTALRVGDAMLAPLPCYAVDPVDPPPAWSALIAAPAILLAHSARAAERVAALAGT
HHCCCCCEEEECCHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ARGHLSLVAISAAVAQAAGAGWRVCAVAAEANDAAMLAQARALWHKGAK
CCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDGAPLIVTRPEPGNAATVARARALGFDVHAMPLFAARPLDWTPPDAADFDALLLTSAF
CCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHH
AARLAGPGLGALASLPAYAVGPATAEAARAAGLTVAMAGAAGAERLLDDMTSSEIARILW
HHHHCCCCCHHHHHCCCHHCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
LCGRDRTALRVGDAMLAPLPCYAVDPVDPPPAWSALIAAPAILLAHSARAAERVAALAGT
HHCCCCCEEEECCHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ARGHLSLVAISAAVAQAAGAGWRVCAVAAEANDAAMLAQARALWHKGAK
CCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA