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The map label for this gene is gcp

Identifier: 103488352

GI number: 103488352

Start: 3026366

End: 3027400

Strand: Reverse

Name: gcp

Synonym: Sala_2875

Alternate gene names: 103488352

Gene position: 3027400-3026366 (Counterclockwise)

Preceding gene: 103488359

Following gene: 103488351

Centisome position: 90.5

GC content: 71.98

Gene sequence:

>1035_bases
ATGACCCTGATCCTCGGCCTCGAATCGAGCTGCGACGAAACGGCAGCGGCGCTTGTCACCGGCGACCGGCGCGTCCTCGC
GCACCGCGTTGCGGGACAGGAGGCCGAACACCGGCCCTATGGCGGCGTGGTACCCGAAATCGCCGCGCGCGCGCATGTCG
ACCGGCTCGCGCCGATCGTCGAAGGCGTGCTCGATGACGCGGGCGTGACGCTCGCCGACGTCGATGCGATCGCAGCGACC
GCCGGGCCGGGGCTGATCGGCGGGGTGATGGTCGGCCTCGTCACCGGCAAGGCGCTGGCGCACGCCGCGAACAAGCCGCT
GATCGCGGTCAACCATCTCGAGGGCCATGCGCTCAGCCCGCGGCTCGCCGATCCGACCCTCGACTTTCCCTATCTGCTGC
TGCTCGTCTCGGGCGGGCATTGCCAGTTGCTGCTCGTAAAGGGCGTCGGCGATTATCGCCGTCTCGCCACCACGATCGAC
GATGCCGCGGGCGAGGCGTTCGACAAGACCGCCAAGCTGCTCGGCCTCGGCTATCCGGGTGGTCCCGCGGTCGAACGCAT
CGCGGCCGAAGGCGACCCGCACGCCGTGCCGCTGCCGCGCCCGCTCGTCGGCAGCGCCGAGCCGCATTTCTCCTTTGCCG
GGCTGAAAAGCGCGGTCGCGCGCGCCGCGGCGAGCGGAACCCATGACGTTGCCGATCTCGCTGCCTCGTTCCAGCAGGCC
GTCGTCGACTGCCTCGTCGATCGCAGCCGCGGCGCGCTCGCGGCGTGCCCCGATGCCAGGGCCTTCGTCGTCGCGGGCGG
CGTCGCGGCCAATGGCGCGATCCGCACCGCGCTCACCGACCTCGCCGCGCGCTTCGACAAGCCCTTCGTCGCGCCGCCGC
TGTGGCTCTGCACCGACAATGGCGCGATGATCGCCTGGGCGGGCGCCGAACGCTTTGCCGCGGGGCTGACCGACCCGCTC
GATACTGCGGCGCGCCCGCGCTGGCCGCTCGACCCCGCAGCCGAAGCAGTGCGCGGCGCGGGAGTGAAAGCATGA

Upstream 100 bases:

>100_bases
TGCGAAGCGGGTTGTCGGGGGTCGCAAGCTCGTTCATCCGGCTGCTGCTAGCGCGGCTTGCCCTTCCGATAAAGGGGCGG
GTAAAGGAACGCGCGACAAT

Downstream 100 bases:

>100_bases
CGTCGTATCGCAATTTCGGCATTGTCGGCGGCGGAGCGTGGGGCACCGCGCTGGCGCAGCTCCTCGCCGCCGATGGCGCG
CCGGTGCGCCTGTGGGCGCG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTLILGLESSCDETAAALVTGDRRVLAHRVAGQEAEHRPYGGVVPEIAARAHVDRLAPIVEGVLDDAGVTLADVDAIAAT
AGPGLIGGVMVGLVTGKALAHAANKPLIAVNHLEGHALSPRLADPTLDFPYLLLLVSGGHCQLLLVKGVGDYRRLATTID
DAAGEAFDKTAKLLGLGYPGGPAVERIAAEGDPHAVPLPRPLVGSAEPHFSFAGLKSAVARAAASGTHDVADLAASFQQA
VVDCLVDRSRGALAACPDARAFVVAGGVAANGAIRTALTDLAARFDKPFVAPPLWLCTDNGAMIAWAGAERFAAGLTDPL
DTAARPRWPLDPAAEAVRGAGVKA

Sequences:

>Translated_344_residues
MTLILGLESSCDETAAALVTGDRRVLAHRVAGQEAEHRPYGGVVPEIAARAHVDRLAPIVEGVLDDAGVTLADVDAIAAT
AGPGLIGGVMVGLVTGKALAHAANKPLIAVNHLEGHALSPRLADPTLDFPYLLLLVSGGHCQLLLVKGVGDYRRLATTID
DAAGEAFDKTAKLLGLGYPGGPAVERIAAEGDPHAVPLPRPLVGSAEPHFSFAGLKSAVARAAASGTHDVADLAASFQQA
VVDCLVDRSRGALAACPDARAFVVAGGVAANGAIRTALTDLAARFDKPFVAPPLWLCTDNGAMIAWAGAERFAAGLTDPL
DTAARPRWPLDPAAEAVRGAGVKA
>Mature_343_residues
TLILGLESSCDETAAALVTGDRRVLAHRVAGQEAEHRPYGGVVPEIAARAHVDRLAPIVEGVLDDAGVTLADVDAIAATA
GPGLIGGVMVGLVTGKALAHAANKPLIAVNHLEGHALSPRLADPTLDFPYLLLLVSGGHCQLLLVKGVGDYRRLATTIDD
AAGEAFDKTAKLLGLGYPGGPAVERIAAEGDPHAVPLPRPLVGSAEPHFSFAGLKSAVARAAASGTHDVADLAASFQQAV
VDCLVDRSRGALAACPDARAFVVAGGVAANGAIRTALTDLAARFDKPFVAPPLWLCTDNGAMIAWAGAERFAAGLTDPLD
TAARPRWPLDPAAEAVRGAGVKA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=356, Percent_Identity=37.3595505617978, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI8923380, Length=342, Percent_Identity=31.8713450292398, Blast_Score=125, Evalue=7e-29,
Organism=Escherichia coli, GI1789445, Length=331, Percent_Identity=48.036253776435, Blast_Score=290, Evalue=8e-80,
Organism=Caenorhabditis elegans, GI17557464, Length=323, Percent_Identity=33.1269349845201, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71995670, Length=343, Percent_Identity=29.1545189504373, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320099, Length=363, Percent_Identity=31.6804407713499, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322891, Length=330, Percent_Identity=25.4545454545455, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129063, Length=360, Percent_Identity=34.4444444444444, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21357207, Length=344, Percent_Identity=28.4883720930233, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_SPHAL (Q1GP42)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_617913.1
- ProteinModelPortal:   Q1GP42
- SMR:   Q1GP42
- MEROPS:   M22.001
- GeneID:   4080668
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_2875
- NMPDR:   fig|317655.9.peg.2737
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   SALA317655:SALA_2875-MONOMER
- BRENDA:   3.4.24.57
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35076; Mature: 34945

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLILGLESSCDETAAALVTGDRRVLAHRVAGQEAEHRPYGGVVPEIAARAHVDRLAPIV
CEEEEECCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EGVLDDAGVTLADVDAIAATAGPGLIGGVMVGLVTGKALAHAANKPLIAVNHLEGHALSP
HHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
RLADPTLDFPYLLLLVSGGHCQLLLVKGVGDYRRLATTIDDAAGEAFDKTAKLLGLGYPG
CCCCCCCCHHEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GPAVERIAAEGDPHAVPLPRPLVGSAEPHFSFAGLKSAVARAAASGTHDVADLAASFQQA
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VVDCLVDRSRGALAACPDARAFVVAGGVAANGAIRTALTDLAARFDKPFVAPPLWLCTDN
HHHHHHHCCCCCEEECCCCCEEEEECCHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECC
GAMIAWAGAERFAAGLTDPLDTAARPRWPLDPAAEAVRGAGVKA
CCEEEECCHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
TLILGLESSCDETAAALVTGDRRVLAHRVAGQEAEHRPYGGVVPEIAARAHVDRLAPIV
EEEEECCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EGVLDDAGVTLADVDAIAATAGPGLIGGVMVGLVTGKALAHAANKPLIAVNHLEGHALSP
HHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
RLADPTLDFPYLLLLVSGGHCQLLLVKGVGDYRRLATTIDDAAGEAFDKTAKLLGLGYPG
CCCCCCCCHHEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GPAVERIAAEGDPHAVPLPRPLVGSAEPHFSFAGLKSAVARAAASGTHDVADLAASFQQA
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VVDCLVDRSRGALAACPDARAFVVAGGVAANGAIRTALTDLAARFDKPFVAPPLWLCTDN
HHHHHHHCCCCCEEECCCCCEEEEECCHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECC
GAMIAWAGAERFAAGLTDPLDTAARPRWPLDPAAEAVRGAGVKA
CCEEEECCHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA