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The map label for this gene is gpsA

Identifier: 103488351

GI number: 103488351

Start: 3025377

End: 3026369

Strand: Reverse

Name: gpsA

Synonym: Sala_2874

Alternate gene names: 103488351

Gene position: 3026369-3025377 (Counterclockwise)

Preceding gene: 103488352

Following gene: 103488350

Centisome position: 90.47

GC content: 71.9

Gene sequence:

>993_bases
ATGACGTCGTATCGCAATTTCGGCATTGTCGGCGGCGGAGCGTGGGGCACCGCGCTGGCGCAGCTCCTCGCCGCCGATGG
CGCGCCGGTGCGCCTGTGGGCGCGCGAGGCCGATGTGGTCGCCGCGATCAATGCCGAGCATCGCAATCCGGTCTTCCTTC
CCGGCGCGCCGCTCTCCTCGTCGCTCACCGCCACCACCGATCTGGCGGCGATGACCGATCTCGACGCGCTGCTGGTCGTC
GTCCCCGTGCCCTATCTGCGCGCCGTGCTCACCGAACTGCCGCCGGGCGACGCGCCGCTGGTCTTTTGCAGCAAGGGGAT
GGAGGCGGGCAGTTTCGCCTTCCCGGTCGACATGGCGCGCGACCTGGCGCCCGGTCGCCCGCACGCGGTGCTGTCGGGCC
CGACCTTTGCGCATGAAGTCGCCGCCGGCCTGCCGACCGCGATCACGCTCGCCGCCGCCGACCCCGCGCTCGCCACCGAG
CTTGCGCAGGCGCTCGCGCGCCCGCATTTCCGCCCCTATGTGTCGACCGACGTGATCGGCGCCGAAATCGGCGGGGCGGT
CAAGAACATCCTCGCGATCGCGTGCGGCATCGTCGAAGGGGCGGGACTCGGGCTCAACGCGCGCGCGGCGCTGATCAGCC
GGGGCTTTGCCGAAATGACGCGCTTCGGCCTGTCGCGCGGGGCAAAGGCCGAAACGCTCGCGGGTCTCGCCGGGCTCGGC
GACCTCGTGCTCACCTGCACCTCCGCCAATTCGCGCAATTTCGCGCTTGGTCAGGGACTGGGACGCGGCGAGGCGATCGA
GACGCTGATGGCCGACCGGCGCACGATCGCCGAGGGCGCATTCAGCGCCCCGGTCGTCGCCGCTGCGGCGCGTGCCGACG
GGGTCGACATGCCGATCACCGACACCGTCGCGCGCCTCGTCGCGGGCGAGATGCGCGTCGCCGACGCCATTCAGGCCCTG
CTCAGCCGCCCGCTGCGACCCGAAGGGCAATGA

Upstream 100 bases:

>100_bases
GCTTTGCCGCGGGGCTGACCGACCCGCTCGATACTGCGGCGCGCCCGCGCTGGCCGCTCGACCCCGCAGCCGAAGCAGTG
CGCGGCGCGGGAGTGAAAGC

Downstream 100 bases:

>100_bases
CAGATTTCCACCGATTGCCTGCCCCTTCCCGCCGCGCTAGGATGCCCGCCGGGGATCAGCAGAAGGGGCGCGAGGCTTGA
GCCAGACGGACAGCGCAGCC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTSYRNFGIVGGGAWGTALAQLLAADGAPVRLWAREADVVAAINAEHRNPVFLPGAPLSSSLTATTDLAAMTDLDALLVV
VPVPYLRAVLTELPPGDAPLVFCSKGMEAGSFAFPVDMARDLAPGRPHAVLSGPTFAHEVAAGLPTAITLAAADPALATE
LAQALARPHFRPYVSTDVIGAEIGGAVKNILAIACGIVEGAGLGLNARAALISRGFAEMTRFGLSRGAKAETLAGLAGLG
DLVLTCTSANSRNFALGQGLGRGEAIETLMADRRTIAEGAFSAPVVAAAARADGVDMPITDTVARLVAGEMRVADAIQAL
LSRPLRPEGQ

Sequences:

>Translated_330_residues
MTSYRNFGIVGGGAWGTALAQLLAADGAPVRLWAREADVVAAINAEHRNPVFLPGAPLSSSLTATTDLAAMTDLDALLVV
VPVPYLRAVLTELPPGDAPLVFCSKGMEAGSFAFPVDMARDLAPGRPHAVLSGPTFAHEVAAGLPTAITLAAADPALATE
LAQALARPHFRPYVSTDVIGAEIGGAVKNILAIACGIVEGAGLGLNARAALISRGFAEMTRFGLSRGAKAETLAGLAGLG
DLVLTCTSANSRNFALGQGLGRGEAIETLMADRRTIAEGAFSAPVVAAAARADGVDMPITDTVARLVAGEMRVADAIQAL
LSRPLRPEGQ
>Mature_329_residues
TSYRNFGIVGGGAWGTALAQLLAADGAPVRLWAREADVVAAINAEHRNPVFLPGAPLSSSLTATTDLAAMTDLDALLVVV
PVPYLRAVLTELPPGDAPLVFCSKGMEAGSFAFPVDMARDLAPGRPHAVLSGPTFAHEVAAGLPTAITLAAADPALATEL
AQALARPHFRPYVSTDVIGAEIGGAVKNILAIACGIVEGAGLGLNARAALISRGFAEMTRFGLSRGAKAETLAGLAGLGD
LVLTCTSANSRNFALGQGLGRGEAIETLMADRRTIAEGAFSAPVVAAAARADGVDMPITDTVARLVAGEMRVADAIQALL
SRPLRPEGQ

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=290, Percent_Identity=30, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI24307999, Length=342, Percent_Identity=27.7777777777778, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1790037, Length=326, Percent_Identity=42.0245398773006, Blast_Score=222, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI32564399, Length=348, Percent_Identity=27.0114942528736, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI193210136, Length=357, Percent_Identity=26.3305322128852, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32564403, Length=357, Percent_Identity=26.3305322128852, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17507425, Length=278, Percent_Identity=29.136690647482, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193210134, Length=337, Percent_Identity=25.2225519287834, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320181, Length=277, Percent_Identity=31.7689530685921, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324513, Length=345, Percent_Identity=28.695652173913, Blast_Score=105, Evalue=8e-24,
Organism=Drosophila melanogaster, GI17136204, Length=351, Percent_Identity=27.9202279202279, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI17136202, Length=351, Percent_Identity=27.9202279202279, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI17136200, Length=351, Percent_Identity=27.9202279202279, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI22026922, Length=342, Percent_Identity=25.1461988304094, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45551945, Length=342, Percent_Identity=25.1461988304094, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281362270, Length=231, Percent_Identity=27.7056277056277, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648969, Length=305, Percent_Identity=25.5737704918033, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA1_SPHAL (Q1GP43)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_617912.1
- ProteinModelPortal:   Q1GP43
- SMR:   Q1GP43
- GeneID:   4080667
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_2874
- NMPDR:   fig|317655.9.peg.2736
- HOGENOM:   HBG586392
- OMA:   AKGIEHG
- ProtClustDB:   PRK00094
- BioCyc:   SALA317655:SALA_2874-MONOMER
- BRENDA:   1.1.1.94
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 33648; Mature: 33517

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 188-188 BINDING 105-105 BINDING 105-105 BINDING 137-137 BINDING 252-252 BINDING 278-278

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYRNFGIVGGGAWGTALAQLLAADGAPVRLWAREADVVAAINAEHRNPVFLPGAPLSS
CCCCCCCCEEECCHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCEEECCCCCCC
SLTATTDLAAMTDLDALLVVVPVPYLRAVLTELPPGDAPLVFCSKGMEAGSFAFPVDMAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEECCHHHHH
DLAPGRPHAVLSGPTFAHEVAAGLPTAITLAAADPALATELAQALARPHFRPYVSTDVIG
HCCCCCCCEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHH
AEIGGAVKNILAIACGIVEGAGLGLNARAALISRGFAEMTRFGLSRGAKAETLAGLAGLG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
DLVLTCTSANSRNFALGQGLGRGEAIETLMADRRTIAEGAFSAPVVAAAARADGVDMPIT
CEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHH
DTVARLVAGEMRVADAIQALLSRPLRPEGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSYRNFGIVGGGAWGTALAQLLAADGAPVRLWAREADVVAAINAEHRNPVFLPGAPLSS
CCCCCCCEEECCHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCEEECCCCCCC
SLTATTDLAAMTDLDALLVVVPVPYLRAVLTELPPGDAPLVFCSKGMEAGSFAFPVDMAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEECCHHHHH
DLAPGRPHAVLSGPTFAHEVAAGLPTAITLAAADPALATELAQALARPHFRPYVSTDVIG
HCCCCCCCEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHH
AEIGGAVKNILAIACGIVEGAGLGLNARAALISRGFAEMTRFGLSRGAKAETLAGLAGLG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
DLVLTCTSANSRNFALGQGLGRGEAIETLMADRRTIAEGAFSAPVVAAAARADGVDMPIT
CEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHH
DTVARLVAGEMRVADAIQALLSRPLRPEGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA