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The map label for this gene is ppx [H]

Identifier: 103488230

GI number: 103488230

Start: 2901908

End: 2902999

Strand: Direct

Name: ppx [H]

Synonym: Sala_2753

Alternate gene names: 103488230

Gene position: 2901908-2902999 (Clockwise)

Preceding gene: 103488229

Following gene: 103488231

Centisome position: 86.75

GC content: 69.78

Gene sequence:

>1092_bases
ATGCGGCAAATGGCAGCGCCATCAGAGCGACCGCCGCGGCCCGGGTCGGCGGCAAAAGGACGGAACAAGGCGAGCGCCCC
CCGGCGACCGATTCCGGTCGTTCGACCACGCAGCTATGCCGCAATCGACCTTGGCACCAACAATTGCCGCCTGCTCATTG
CCCGGCCGCAGGATGGCGAGCTGGTCGTCATCGACGCCTTTTCACGCATCGTGCGGCTTGGCGAAGGGCTGCACAGCACC
GGGCGAATCAGCGAGGCGGCGATGGATCGCACCGTCGCGGCGCTCGCCATCTGCGCCGACAAGCTGCGCCGCCGCCACGT
CTCGCTGTCGCGCGCGGTTGCGACCGAAGCGTGCCGCCGCGCGAGCAACGGCGCCGAGCTGGCCGAACGCGTCCGGCGCG
AAACGGGGATCGTTCTGGATATCATCTCCGCCGCCGAGGAGGCGCGACTGGCGGTGCTTGGCTGCCACAATCTGATGGAA
CCCGGCGACGGTCCCGCCCTGATCTTTGACATCGGCGGCGGCTCGACCGAGTTGATGCGCGTGGAAATGTCGGACCATGA
CGTCCAGATTCACGACTGGGTCAGCGTGCCGTGGGGCGTCGTGTCGCTGACCGAACATGCCCCGCTGCCCGACGACAGCC
TGTCCGGGCGCCAGGCGGCCTATGCGCATATGCGCGACGTGACGCGGCAGGCCTTTGCCGCCTTTGCCGACCGCGCGGGG
GCCTTTGCCGGTCAGCCGCTGCGCCTGCTCGGCACCAGCGGCACGGTGACGACGCTCGCCAGCGTGTTCCTGAACCTGCC
GCGATACGACCGGCGCGCGGTCGATGGCCTGGTCGTGCCCAGCGACGCGATGCGCGCGATCAGCCGCCGCCTCGCCGACG
CCAGCATCGCCGACCGCGCCGAAATCGCCTGCATCGGCCGCGAACGCGCCGATCTGGTCGTCGCGGGCTGCGCGATCCTC
GAAAGCATCATCGACCTGTGGCCCGCCGCGCGCGTCGGCGTCGCCGATCGCGGAATCCGCGAGGGCATCCTGCGCACGCT
GGCGATGCAGGGCCGCGACATTCCGGTCACGCGCCGCGAATATCGCAAATGA

Upstream 100 bases:

>100_bases
GCGCAGGGTGCTTGCCATCGGCCCGGCGCGCGCCTAGGTTTGCCGCCAAGTGCACGCCCGCGGTCCTGCGGGCGCGTGAG
CAGAACAGGTTACAATTGCC

Downstream 100 bases:

>100_bases
GCGGCAGCGGCGGCAAGGGCGGCGGCCGCGGCGGTCTGCACGTGCGGGTCAAGACCGCGAAAAGGCGCAGCGTGTCGTCG
ACGCGCTGGCTGCAGCGGCA

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MRQMAAPSERPPRPGSAAKGRNKASAPRRPIPVVRPRSYAAIDLGTNNCRLLIARPQDGELVVIDAFSRIVRLGEGLHST
GRISEAAMDRTVAALAICADKLRRRHVSLSRAVATEACRRASNGAELAERVRRETGIVLDIISAAEEARLAVLGCHNLME
PGDGPALIFDIGGGSTELMRVEMSDHDVQIHDWVSVPWGVVSLTEHAPLPDDSLSGRQAAYAHMRDVTRQAFAAFADRAG
AFAGQPLRLLGTSGTVTTLASVFLNLPRYDRRAVDGLVVPSDAMRAISRRLADASIADRAEIACIGRERADLVVAGCAIL
ESIIDLWPAARVGVADRGIREGILRTLAMQGRDIPVTRREYRK

Sequences:

>Translated_363_residues
MRQMAAPSERPPRPGSAAKGRNKASAPRRPIPVVRPRSYAAIDLGTNNCRLLIARPQDGELVVIDAFSRIVRLGEGLHST
GRISEAAMDRTVAALAICADKLRRRHVSLSRAVATEACRRASNGAELAERVRRETGIVLDIISAAEEARLAVLGCHNLME
PGDGPALIFDIGGGSTELMRVEMSDHDVQIHDWVSVPWGVVSLTEHAPLPDDSLSGRQAAYAHMRDVTRQAFAAFADRAG
AFAGQPLRLLGTSGTVTTLASVFLNLPRYDRRAVDGLVVPSDAMRAISRRLADASIADRAEIACIGRERADLVVAGCAIL
ESIIDLWPAARVGVADRGIREGILRTLAMQGRDIPVTRREYRK
>Mature_363_residues
MRQMAAPSERPPRPGSAAKGRNKASAPRRPIPVVRPRSYAAIDLGTNNCRLLIARPQDGELVVIDAFSRIVRLGEGLHST
GRISEAAMDRTVAALAICADKLRRRHVSLSRAVATEACRRASNGAELAERVRRETGIVLDIISAAEEARLAVLGCHNLME
PGDGPALIFDIGGGSTELMRVEMSDHDVQIHDWVSVPWGVVSLTEHAPLPDDSLSGRQAAYAHMRDVTRQAFAAFADRAG
AFAGQPLRLLGTSGTVTTLASVFLNLPRYDRRAVDGLVVPSDAMRAISRRLADASIADRAEIACIGRERADLVVAGCAIL
ESIIDLWPAARVGVADRGIREGILRTLAMQGRDIPVTRREYRK

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate of circa 500 residues long, while chains of circa 15 residues compete poorly with polyphosphate as substrate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=326, Percent_Identity=27.9141104294479, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI48994966, Length=306, Percent_Identity=28.1045751633987, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 39222; Mature: 39222

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQMAAPSERPPRPGSAAKGRNKASAPRRPIPVVRPRSYAAIDLGTNNCRLLIARPQDGE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCC
LVVIDAFSRIVRLGEGLHSTGRISEAAMDRTVAALAICADKLRRRHVSLSRAVATEACRR
EEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASNGAELAERVRRETGIVLDIISAAEEARLAVLGCHNLMEPGDGPALIFDIGGGSTELMR
CCCHHHHHHHHHHHCCCEEEHHHHHHHHHEEEEEHHHHCCCCCCCEEEEECCCCCEEEEE
VEMSDHDVQIHDWVSVPWGVVSLTEHAPLPDDSLSGRQAAYAHMRDVTRQAFAAFADRAG
EEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
AFAGQPLRLLGTSGTVTTLASVFLNLPRYDRRAVDGLVVPSDAMRAISRRLADASIADRA
CCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHCCEECCHHHHHHHHHHHHCCHHCCCC
EIACIGRERADLVVAGCAILESIIDLWPAARVGVADRGIREGILRTLAMQGRDIPVTRRE
CEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
YRK
HCC
>Mature Secondary Structure
MRQMAAPSERPPRPGSAAKGRNKASAPRRPIPVVRPRSYAAIDLGTNNCRLLIARPQDGE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCC
LVVIDAFSRIVRLGEGLHSTGRISEAAMDRTVAALAICADKLRRRHVSLSRAVATEACRR
EEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASNGAELAERVRRETGIVLDIISAAEEARLAVLGCHNLMEPGDGPALIFDIGGGSTELMR
CCCHHHHHHHHHHHCCCEEEHHHHHHHHHEEEEEHHHHCCCCCCCEEEEECCCCCEEEEE
VEMSDHDVQIHDWVSVPWGVVSLTEHAPLPDDSLSGRQAAYAHMRDVTRQAFAAFADRAG
EEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
AFAGQPLRLLGTSGTVTTLASVFLNLPRYDRRAVDGLVVPSDAMRAISRRLADASIADRA
CCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHCCEECCHHHHHHHHHHHHCCHHCCCC
EIACIGRERADLVVAGCAILESIIDLWPAARVGVADRGIREGILRTLAMQGRDIPVTRRE
CEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
YRK
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]