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The map label for this gene is arsB [H]

Identifier: 103487885

GI number: 103487885

Start: 2539146

End: 2540210

Strand: Direct

Name: arsB [H]

Synonym: Sala_2405

Alternate gene names: 103487885

Gene position: 2539146-2540210 (Clockwise)

Preceding gene: 103487884

Following gene: 103487886

Centisome position: 75.9

GC content: 61.5

Gene sequence:

>1065_bases
ATGACAGAACCCAAGCGGGAACGGCTGTCGTTCCTCGATCGCTATCTCACCCTCTGGATCTTCCTCGCGATGGCGCTCGG
CGTGTTGCTCGGTTCGGTGTTCACCGGCCTGCCCGCCGCGATCGATGCCCTCTCGTGGGGCTCGACCAACATCCCGATCG
CGATCGGCCTTATCCTGATGATGTATCCGCCGCTCGCGCGCGTCCGCTACGAGGAATTGCCGCGCGTGTTCGAGGACAAA
AGGGTGCTCGCCATCTCGCTCATCCAGAACTGGATCATCGGTCCCGTGCTGATGTTCGCGCTCGCGGTGATCTTCCTGTC
AGACAAGCCCGAATATATGACCGGGCTGATCCTGATCGGCCTCGCGCGCTGCATCGCGATGGTGATCGTCTGGAACCAGC
TCGCGAAGGGCGACAATCAATATGTCGCGGCACTGGTGGCGTTCAACTCGATCTTCCAGATCCTGTTCTTCAGCATCTAT
GCCTGGTTCTTCCTGACGATATTGCCGCCGCTGTTCGGTCTCGAAGGCAGCGTTATCGACGTAAGCTTCTGGACCGTCGC
CGAAGCCGTCCTCATTTATCTCGGCGTTCCCTTTGCGGCGGGCTATCTCACTCGCAAGTGGCTCGCAGACGCCAAGGGCA
ACGAATGGTATGAGACGCGCTTCCTCCCGCGCATCGCGCCGATCACGCTTGTCGCGCTGCTCTTCACGATCGTCGCAATG
TTCAGCCTCAAGGGCGGTGAGATCGTCACCATTCCCGGCGACGTCGTGCGCATCGCCGTCCCGCTGACCATCTATTTCGT
CGTGCAGTTCGTCATCAGCTTCTGGATGGGCAAGCTGATCGAGGCCGATTATCCGCGCACGACCGCGGTCGCCTTCACCG
CCGCCGGAAATAATTTCGAGCTTGCGATCGCGGTTGCGATTGCCGCCTTCGGGCTCGCCTCGCCGGTCGCCTTCGCCGCC
GTCATCGGCCCGCTCGTCGAAGTTCCCGTGCTCATCCTGCTGGTGAGCGTCGCCTTCTGGTTCGGACGCCGCTGGTTCCC
GGCATCCACCCCCGCGAAAGACTGA

Upstream 100 bases:

>100_bases
CGACCTCATCCCTGCGGGGCAACGCGGCGCCTTCGCCAAGGAAGACGGCGAACAGGTAATCGACGCCGCTGGCAACCGCG
TCGGCGCCTGAGCCAAGCCG

Downstream 100 bases:

>100_bases
TTGTCATGGCTTCCCCCACCTTTTCGCGCCTGCGCGCGCTCGCCGATCCCACCCATCTTCCGGCGCTCAGCGCGGAATAT
ATCCGCTCGCAGCCCGCGCT

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTEPKRERLSFLDRYLTLWIFLAMALGVLLGSVFTGLPAAIDALSWGSTNIPIAIGLILMMYPPLARVRYEELPRVFEDK
RVLAISLIQNWIIGPVLMFALAVIFLSDKPEYMTGLILIGLARCIAMVIVWNQLAKGDNQYVAALVAFNSIFQILFFSIY
AWFFLTILPPLFGLEGSVIDVSFWTVAEAVLIYLGVPFAAGYLTRKWLADAKGNEWYETRFLPRIAPITLVALLFTIVAM
FSLKGGEIVTIPGDVVRIAVPLTIYFVVQFVISFWMGKLIEADYPRTTAVAFTAAGNNFELAIAVAIAAFGLASPVAFAA
VIGPLVEVPVLILLVSVAFWFGRRWFPASTPAKD

Sequences:

>Translated_354_residues
MTEPKRERLSFLDRYLTLWIFLAMALGVLLGSVFTGLPAAIDALSWGSTNIPIAIGLILMMYPPLARVRYEELPRVFEDK
RVLAISLIQNWIIGPVLMFALAVIFLSDKPEYMTGLILIGLARCIAMVIVWNQLAKGDNQYVAALVAFNSIFQILFFSIY
AWFFLTILPPLFGLEGSVIDVSFWTVAEAVLIYLGVPFAAGYLTRKWLADAKGNEWYETRFLPRIAPITLVALLFTIVAM
FSLKGGEIVTIPGDVVRIAVPLTIYFVVQFVISFWMGKLIEADYPRTTAVAFTAAGNNFELAIAVAIAAFGLASPVAFAA
VIGPLVEVPVLILLVSVAFWFGRRWFPASTPAKD
>Mature_353_residues
TEPKRERLSFLDRYLTLWIFLAMALGVLLGSVFTGLPAAIDALSWGSTNIPIAIGLILMMYPPLARVRYEELPRVFEDKR
VLAISLIQNWIIGPVLMFALAVIFLSDKPEYMTGLILIGLARCIAMVIVWNQLAKGDNQYVAALVAFNSIFQILFFSIYA
WFFLTILPPLFGLEGSVIDVSFWTVAEAVLIYLGVPFAAGYLTRKWLADAKGNEWYETRFLPRIAPITLVALLFTIVAMF
SLKGGEIVTIPGDVVRIAVPLTIYFVVQFVISFWMGKLIEADYPRTTAVAFTAAGNNFELAIAVAIAAFGLASPVAFAAV
IGPLVEVPVLILLVSVAFWFGRRWFPASTPAKD

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=320, Percent_Identity=34.375, Blast_Score=170, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39145; Mature: 39014

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPKRERLSFLDRYLTLWIFLAMALGVLLGSVFTGLPAAIDALSWGSTNIPIAIGLILM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHH
MYPPLARVRYEELPRVFEDKRVLAISLIQNWIIGPVLMFALAVIFLSDKPEYMTGLILIG
HCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LARCIAMVIVWNQLAKGDNQYVAALVAFNSIFQILFFSIYAWFFLTILPPLFGLEGSVID
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VSFWTVAEAVLIYLGVPFAAGYLTRKWLADAKGNEWYETRFLPRIAPITLVALLFTIVAM
EHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
FSLKGGEIVTIPGDVVRIAVPLTIYFVVQFVISFWMGKLIEADYPRTTAVAFTAAGNNFE
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCH
LAIAVAIAAFGLASPVAFAAVIGPLVEVPVLILLVSVAFWFGRRWFPASTPAKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TEPKRERLSFLDRYLTLWIFLAMALGVLLGSVFTGLPAAIDALSWGSTNIPIAIGLILM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHH
MYPPLARVRYEELPRVFEDKRVLAISLIQNWIIGPVLMFALAVIFLSDKPEYMTGLILIG
HCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LARCIAMVIVWNQLAKGDNQYVAALVAFNSIFQILFFSIYAWFFLTILPPLFGLEGSVID
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VSFWTVAEAVLIYLGVPFAAGYLTRKWLADAKGNEWYETRFLPRIAPITLVALLFTIVAM
EHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
FSLKGGEIVTIPGDVVRIAVPLTIYFVVQFVISFWMGKLIEADYPRTTAVAFTAAGNNFE
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCH
LAIAVAIAAFGLASPVAFAAVIGPLVEVPVLILLVSVAFWFGRRWFPASTPAKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]